Autophagy suppresses interleukin-1β (IL-1β) signaling by activation of p62 degradation via lysosomal and proteasomal pathways

Journal of Biological Chemistry

Volumn 287, Issue 6, 2012, Pages 4033-4040

  Lee, Jongdae ^a   Kim, Hye Ri ^a   Quinley, Christine ^a   Kim, Joanna ^a   Gonzalez Navajas, Jose ^a   Xavier, Ramnik ^b   Raz, Eyal ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CROHN DISEASE; CYTOKINES; ESSENTIAL COMPONENT; INTERLEUKIN-1; MOUSE EMBRYONIC FIBROBLASTS; NOVEL FUNCTIONS; PROTEASOMAL DEGRADATION; PROTEASOMAL PATHWAY; UBIQUITIN LIGASES;

CELL CULTURE; SIGNAL TRANSDUCTION;

DEGRADATION;

AUTOPHAGY PROTEIN 16 LIKE 1 PROTEIN; CELL PROTEIN; CULLIN; CULLIN 3; INTERLEUKIN 1BETA; PROTEASOME; PROTEIN P62; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOLYSOSOME; AUTOPHAGY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; FIBROBLAST; GENE DELETION; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AUTOPHAGY; CARRIER PROTEINS; CELLS, CULTURED; CULLIN PROTEINS; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; FIBROBLASTS; GENE DELETION; HEAT-SHOCK PROTEINS; INTERLEUKIN-1BETA; MICE; MICE, KNOCKOUT; PROTEASOME ENDOPEPTIDASE COMPLEX; SIGNAL TRANSDUCTION;

EID: 84863078686     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.280065     Document Type: Article

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