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Volumn 7, Issue , 2013, Pages

Decision tree-based method for integrating gene expression, demographic, and clinical data to determine disease endotypes

Author keywords

Asthma; Endotypes; Gene Expression; Integrated analysis

Indexed keywords

ADOLESCENT; ARTICLE; ASTHMA; BIOLOGY; BLOOD; CHILD; CLUSTER ANALYSIS; DECISION TREE; DEMOGRAPHY; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETICS; HUMAN; METHODOLOGY;

EID: 84886735083     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-7-119     Document Type: Article
Times cited : (29)

References (79)
  • 1
    • 77953303583 scopus 로고    scopus 로고
    • An integrative systems biology approach to understanding pulmonary diseases
    • 10.1378/chest.09-1850, 20525651
    • Auffray C, Adcock IM, Chung KF, Djukanovic R, Pison C, Sterk PJ. An integrative systems biology approach to understanding pulmonary diseases. Chest 2010, 137:1410-1416. 10.1378/chest.09-1850, 20525651.
    • (2010) Chest , vol.137 , pp. 1410-1416
    • Auffray, C.1    Adcock, I.M.2    Chung, K.F.3    Djukanovic, R.4    Pison, C.5    Sterk, P.J.6
  • 2
    • 35448941232 scopus 로고    scopus 로고
    • Molecular epidemiology and biomarkers in etiologic cancer research: the new in light of the old
    • 10.1158/1055-9965.EPI-07-0457, 17932342
    • Vineis P, Perera F. Molecular epidemiology and biomarkers in etiologic cancer research: the new in light of the old. Cancer Epidemiol Biomarkers Prev 2007, 16:1954-1965. 10.1158/1055-9965.EPI-07-0457, 17932342.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1954-1965
    • Vineis, P.1    Perera, F.2
  • 3
    • 55249109737 scopus 로고    scopus 로고
    • Genetics and genomics: gene expression microarrays
    • 10.1161/CIRCULATIONAHA.107.714600, 18838575
    • Ballman KV. Genetics and genomics: gene expression microarrays. Circulation 2008, 118:1593-1597. 10.1161/CIRCULATIONAHA.107.714600, 18838575.
    • (2008) Circulation , vol.118 , pp. 1593-1597
    • Ballman, K.V.1
  • 4
    • 36249024700 scopus 로고    scopus 로고
    • Transcriptional responses to complex mixtures: a review
    • 10.1016/j.mrrev.2007.08.002, 17888717
    • Sen B, Mahadevan B, DeMarini DM. Transcriptional responses to complex mixtures: a review. Mutation research 2007, 636:144-177. 10.1016/j.mrrev.2007.08.002, 17888717.
    • (2007) Mutation research , vol.636 , pp. 144-177
    • Sen, B.1    Mahadevan, B.2    DeMarini, D.M.3
  • 6
    • 31544483914 scopus 로고    scopus 로고
    • Gene expression by human monocytes from peripheral blood in response to exposure to metals
    • Jost-Albrecht K, Hofstetter W. Gene expression by human monocytes from peripheral blood in response to exposure to metals. J Biomed Mater Res B Appl Biomater 2006, 76:449-455.
    • (2006) J Biomed Mater Res B Appl Biomater , vol.76 , pp. 449-455
    • Jost-Albrecht, K.1    Hofstetter, W.2
  • 12
    • 38149114028 scopus 로고    scopus 로고
    • Simultaneous clustering of gene expression data with clinical chemistry and pathological evaluations reveals phenotypic prototypes
    • 10.1186/1752-0509-1-15, 1839893, 17408499
    • Bushel PR, Wolfinger RD, Gibson G. Simultaneous clustering of gene expression data with clinical chemistry and pathological evaluations reveals phenotypic prototypes. BMC Syst Biol 2007, 1:15. 10.1186/1752-0509-1-15, 1839893, 17408499.
    • (2007) BMC Syst Biol , vol.1 , pp. 15
    • Bushel, P.R.1    Wolfinger, R.D.2    Gibson, G.3
  • 13
    • 33746260458 scopus 로고    scopus 로고
    • Phenotypic anchoring of arsenic and cadmium toxicity in three hepatic-related cell systems reveals compound- and cell-specific selective up-regulation of stress protein expression: implications for fingerprint profiling of cytotoxicity
    • 10.1016/j.cbi.2006.04.003, 16729991
    • Gottschalg E, Moore NE, Ryan AK, Travis LC, Waller RC, Pratt S, Atmaca M, Kind CN, Fry JR. Phenotypic anchoring of arsenic and cadmium toxicity in three hepatic-related cell systems reveals compound- and cell-specific selective up-regulation of stress protein expression: implications for fingerprint profiling of cytotoxicity. Chem Biol Interact 2006, 161:251-261. 10.1016/j.cbi.2006.04.003, 16729991.
    • (2006) Chem Biol Interact , vol.161 , pp. 251-261
    • Gottschalg, E.1    Moore, N.E.2    Ryan, A.K.3    Travis, L.C.4    Waller, R.C.5    Pratt, S.6    Atmaca, M.7    Kind, C.N.8    Fry, J.R.9
  • 14
    • 0038176487 scopus 로고    scopus 로고
    • Phenotypic anchoring: linking cause and effect
    • 10.1289/ehp.111-a338, 1241511, 12760838
    • Paules R. Phenotypic anchoring: linking cause and effect. Environ Health Perspect 2003, 111:A338-A339. 10.1289/ehp.111-a338, 1241511, 12760838.
    • (2003) Environ Health Perspect , vol.111
    • Paules, R.1
  • 15
    • 47649132170 scopus 로고    scopus 로고
    • The environmental contribution to gene expression profiles
    • Gibson G. The environmental contribution to gene expression profiles. Nat Rev Genet 2008, 9:575-581.
    • (2008) Nat Rev Genet , vol.9 , pp. 575-581
    • Gibson, G.1
  • 16
    • 33845336152 scopus 로고    scopus 로고
    • The balance between heritable and environmental aetiology of human disease
    • Hemminki K, Lorenzo Bermejo J, Forsti A
    • Hemminki K, Lorenzo Bermejo J, Forsti A. The balance between heritable and environmental aetiology of human disease. Nat Rev Genet 2006, 7(Hemminki K, Lorenzo Bermejo J, Forsti A):958-965.
    • (2006) Nat Rev Genet , vol.7 , pp. 958-965
    • Hemminki, K.1    Lorenzo Bermejo, J.2    Forsti, A.3
  • 17
    • 35948987588 scopus 로고    scopus 로고
    • Host defense genes in asthma and sepsis and the role of the environment
    • 10.1097/ACI.0b013e3282f1fb9a, 17989521
    • Gao L, Tsai YJ, Grigoryev DN, Barnes KC. Host defense genes in asthma and sepsis and the role of the environment. Curr Opin Allergy Clin Immunol 2007, 7:459-467. 10.1097/ACI.0b013e3282f1fb9a, 17989521.
    • (2007) Curr Opin Allergy Clin Immunol , vol.7 , pp. 459-467
    • Gao, L.1    Tsai, Y.J.2    Grigoryev, D.N.3    Barnes, K.C.4
  • 18
    • 0037184816 scopus 로고    scopus 로고
    • Influences on the development of allergy and asthma
    • Peden DB. Influences on the development of allergy and asthma. Toxicology 2002, 181-182:323-328.
    • (2002) Toxicology , vol.181-182 , pp. 323-328
    • Peden, D.B.1
  • 19
    • 2642585738 scopus 로고    scopus 로고
    • The case for a US prospective cohort study of genes and environment
    • 10.1038/nature02628, 15164074
    • Collins FS. The case for a US prospective cohort study of genes and environment. Nature 2004, 429:475-477. 10.1038/nature02628, 15164074.
    • (2004) Nature , vol.429 , pp. 475-477
    • Collins, F.S.1
  • 20
    • 33847022185 scopus 로고    scopus 로고
    • Genes, environment, health, and disease: facing up to complexity
    • 10.1159/000099178, 17283435
    • Manolio TA, Collins FS. Genes, environment, health, and disease: facing up to complexity. Hum Hered 2007, 63:63-66. 10.1159/000099178, 17283435.
    • (2007) Hum Hered , vol.63 , pp. 63-66
    • Manolio, T.A.1    Collins, F.S.2
  • 22
    • 84862888802 scopus 로고    scopus 로고
    • Novel severe wheezy young children phenotypes: Boys atopic multiple-trigger and girls nonatopic uncontrolled wheeze
    • Just J, Gouvis-Echraghi R, Couderc R, Guillemot-Lambert N, Saint-Pierre P. Novel severe wheezy young children phenotypes: Boys atopic multiple-trigger and girls nonatopic uncontrolled wheeze. J Allergy Clin Immunol 2012, 130(103-110):e108.
    • (2012) J Allergy Clin Immunol , vol.130 , Issue.103-110
    • Just, J.1    Gouvis-Echraghi, R.2    Couderc, R.3    Guillemot-Lambert, N.4    Saint-Pierre, P.5
  • 24
    • 33747756534 scopus 로고    scopus 로고
    • Asthma: defining of the persistent adult phenotypes
    • 10.1016/S0140-6736(06)69290-8, 16935691
    • Wenzel SE. Asthma: defining of the persistent adult phenotypes. Lancet 2006, 368:804-813. 10.1016/S0140-6736(06)69290-8, 16935691.
    • (2006) Lancet , vol.368 , pp. 804-813
    • Wenzel, S.E.1
  • 26
    • 77952537973 scopus 로고    scopus 로고
    • Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation
    • 10.1186/1465-9921-11-30, 2850331, 20233420
    • Cho MH, Washko GR, Hoffmann TJ, Criner GJ, Hoffman EA, Martinez FJ, Laird N, Reilly JJ, Silverman EK. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respir Res 2010, 11:30. 10.1186/1465-9921-11-30, 2850331, 20233420.
    • (2010) Respir Res , vol.11 , pp. 30
    • Cho, M.H.1    Washko, G.R.2    Hoffmann, T.J.3    Criner, G.J.4    Hoffman, E.A.5    Martinez, F.J.6    Laird, N.7    Reilly, J.J.8    Silverman, E.K.9
  • 27
    • 74849094691 scopus 로고    scopus 로고
    • Phenotypic differences between pediatric and adult asthma
    • 10.1513/pats.200906-046DP, 20008882
    • Bush A, Menzies-Gow A. Phenotypic differences between pediatric and adult asthma. Proc Am Thorac Soc 2009, 6:712-719. 10.1513/pats.200906-046DP, 20008882.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 712-719
    • Bush, A.1    Menzies-Gow, A.2
  • 28
    • 79551500941 scopus 로고    scopus 로고
    • Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program
    • e381-313, 10.1016/j.jaci.2010.11.015, 3060668, 21195471, National Institutes of Health/National Heart L
    • Fitzpatrick AM, Teague WG, Meyers DA, Peters SP, Li X, Li H, Wenzel SE, Aujla S, Castro M, Bacharier LB, Gaston BM, Bleecker ER, Moore WC, National Institutes of Health/National Heart L Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol 2011, 127:382-389. e381-313, 10.1016/j.jaci.2010.11.015, 3060668, 21195471, National Institutes of Health/National Heart L.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 382-389
    • Fitzpatrick, A.M.1    Teague, W.G.2    Meyers, D.A.3    Peters, S.P.4    Li, X.5    Li, H.6    Wenzel, S.E.7    Aujla, S.8    Castro, M.9    Bacharier, L.B.10    Gaston, B.M.11    Bleecker, E.R.12    Moore, W.C.13
  • 31
    • 20344372908 scopus 로고    scopus 로고
    • Asthma phenotypes, risk factors, and measures of severity in a national sample of US children
    • 10.1542/peds.2004-0529, 15741378
    • Kelley CF, Mannino DM, Homa DM, Savage-Brown A, Holguin F. Asthma phenotypes, risk factors, and measures of severity in a national sample of US children. Pediatrics 2005, 115:726-731. 10.1542/peds.2004-0529, 15741378.
    • (2005) Pediatrics , vol.115 , pp. 726-731
    • Kelley, C.F.1    Mannino, D.M.2    Homa, D.M.3    Savage-Brown, A.4    Holguin, F.5
  • 32
    • 79959363586 scopus 로고    scopus 로고
    • Human asthma phenotypes: from the clinic, to cytokines, and back again
    • 10.1111/j.1600-065X.2011.01032.x, 3391010, 21682748
    • Bhakta NR, Woodruff PG. Human asthma phenotypes: from the clinic, to cytokines, and back again. Immunol Rev 2011, 242:220-232. 10.1111/j.1600-065X.2011.01032.x, 3391010, 21682748.
    • (2011) Immunol Rev , vol.242 , pp. 220-232
    • Bhakta, N.R.1    Woodruff, P.G.2
  • 36
    • 78650864775 scopus 로고    scopus 로고
    • Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples
    • 160 e151-159, 10.1016/j.jaci.2010.10.024, 21211650
    • Baines KJ, Simpson JL, Wood LG, Scott RJ, Gibson PG. Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples. J Allergy Clin Immunol 2011, 127:153-160. 160 e151-159, 10.1016/j.jaci.2010.10.024, 21211650.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 153-160
    • Baines, K.J.1    Simpson, J.L.2    Wood, L.G.3    Scott, R.J.4    Gibson, P.G.5
  • 40
    • 0036947892 scopus 로고    scopus 로고
    • Robust estimators for expression analysis
    • 10.1093/bioinformatics/18.12.1585, 12490442
    • Hubbell E, Liu WM, Mei R. Robust estimators for expression analysis. Bioinformatics 2002, 18:1585-1592. 10.1093/bioinformatics/18.12.1585, 12490442.
    • (2002) Bioinformatics , vol.18 , pp. 1585-1592
    • Hubbell, E.1    Liu, W.M.2    Mei, R.3
  • 41
    • 0003430544 scopus 로고    scopus 로고
    • Finding Groups in Data: an introduction to cluster analysis
    • Hoboken NJ: John Wiley & Sons, Inc
    • Kaufman LR, Rousseeuw PJ. Finding Groups in Data: an introduction to cluster analysis. Wiley Series in Probability and Statistics 2005, Hoboken NJ: John Wiley & Sons, Inc.
    • (2005) Wiley Series in Probability and Statistics
    • Kaufman, L.R.1    Rousseeuw, P.J.2
  • 42
    • 84950442671 scopus 로고
    • Approximate evaluation technique for the single-link and complete-link hierarchical clustering procedures
    • Hubert L. Approximate evaluation technique for the single-link and complete-link hierarchical clustering procedures. J Am Stat Assoc 1974, 69:698-704.
    • (1974) J Am Stat Assoc , vol.69 , pp. 698-704
    • Hubert, L.1
  • 43
    • 34250115918 scopus 로고
    • An examination of procedures of determining the number of cluster in a data set
    • Milligan GW, Cooper MC. An examination of procedures of determining the number of cluster in a data set. Psychometrika 1985, 50:159-179.
    • (1985) Psychometrika , vol.50 , pp. 159-179
    • Milligan, G.W.1    Cooper, M.C.2
  • 44
    • 65449186592 scopus 로고    scopus 로고
    • Clustering of gene expression data and end-point measurements by simulated annealing
    • 10.1142/S021972000900400X, 2853885, 19226667
    • Bushel PR. Clustering of gene expression data and end-point measurements by simulated annealing. J Bioinform Comput Biol 2009, 7:193-215. 10.1142/S021972000900400X, 2853885, 19226667.
    • (2009) J Bioinform Comput Biol , vol.7 , pp. 193-215
    • Bushel, P.R.1
  • 45
    • 0003500248 scopus 로고
    • C4.5: programs for machine learning
    • San Mateo, CA: Morgan Kaufmann Publishers, Inc
    • Quinlan JR. C4.5: programs for machine learning. Morgan Kaufmann Series in Machine Learning 1993, San Mateo, CA: Morgan Kaufmann Publishers, Inc.
    • (1993) Morgan Kaufmann Series in Machine Learning
    • Quinlan, J.R.1
  • 46
    • 0041382385 scopus 로고    scopus 로고
    • The Netherlands: Kluwer Academic Publishers, Breiman L
    • Random Forests 2001, The Netherlands: Kluwer Academic Publishers, Breiman L.
    • (2001) Random Forests
  • 47
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • 10.1016/S0140-6736(08)61452-X, 18805339
    • Anderson GP. Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 2008, 372:1107-1119. 10.1016/S0140-6736(08)61452-X, 18805339.
    • (2008) Lancet , vol.372 , pp. 1107-1119
    • Anderson, G.P.1
  • 48
    • 84856845581 scopus 로고    scopus 로고
    • Severe asthma: from characteristics to phenotypes to endotypes
    • 10.1111/j.1365-2222.2011.03929.x, 22251060
    • Wenzel S. Severe asthma: from characteristics to phenotypes to endotypes. Clin Exp Allergy 2012, 42:650-658. 10.1111/j.1365-2222.2011.03929.x, 22251060.
    • (2012) Clin Exp Allergy , vol.42 , pp. 650-658
    • Wenzel, S.1
  • 51
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • 10.1038/nature05911, 2719288, 17554300
    • Consortium WTCC. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447:661-678. 10.1038/nature05911, 2719288, 17554300.
    • (2007) Nature , vol.447 , pp. 661-678
    • Consortium, W.T.C.C.1
  • 53
    • 77952557918 scopus 로고    scopus 로고
    • Missing heritability and strategies for finding the underlying causes of complex disease
    • 10.1038/nrg2809, 2942068, 20479774
    • Eichler EE, Flint J, Gibson G, Kong A, Leal SM, Moore JH, Nadeau JH. Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet 2010, 11:446-450. 10.1038/nrg2809, 2942068, 20479774.
    • (2010) Nat Rev Genet , vol.11 , pp. 446-450
    • Eichler, E.E.1    Flint, J.2    Gibson, G.3    Kong, A.4    Leal, S.M.5    Moore, J.H.6    Nadeau, J.H.7
  • 56
    • 70249134919 scopus 로고    scopus 로고
    • Molecular networks as sensors and drivers of common human diseases
    • 10.1038/nature08454, 19741703
    • Schadt EE. Molecular networks as sensors and drivers of common human diseases. Nature 2009, 461:218-223. 10.1038/nature08454, 19741703.
    • (2009) Nature , vol.461 , pp. 218-223
    • Schadt, E.E.1
  • 57
    • 78650623080 scopus 로고    scopus 로고
    • Implications of the exposome for exposure science
    • 10.1038/jes.2010.50, 21081972
    • Rappaport SM. Implications of the exposome for exposure science. J Expo Sci Environ Epidemiol 2011, 21:5-9. 10.1038/jes.2010.50, 21081972.
    • (2011) J Expo Sci Environ Epidemiol , vol.21 , pp. 5-9
    • Rappaport, S.M.1
  • 58
    • 23844523425 scopus 로고    scopus 로고
    • Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology
    • 10.1158/1055-9965.EPI-05-0456, 16103423
    • Wild CP. Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology. Cancer Epidemiol Biomarkers Prev 2005, 14:1847-1850. 10.1158/1055-9965.EPI-05-0456, 16103423.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1847-1850
    • Wild, C.P.1
  • 59
    • 61649092274 scopus 로고    scopus 로고
    • Environmental exposure measurement in cancer epidemiology
    • 2720689, 19033256
    • Wild CP. Environmental exposure measurement in cancer epidemiology. Mutagenesis 2009, 24:117-125. 2720689, 19033256.
    • (2009) Mutagenesis , vol.24 , pp. 117-125
    • Wild, C.P.1
  • 60
    • 77958192172 scopus 로고    scopus 로고
    • Epidemiology Environment and disease risks
    • 10.1126/science.1192603, 20966241
    • Rappaport SM, Smith MT. Epidemiology Environment and disease risks. Science 2010, 330:460-461. 10.1126/science.1192603, 20966241.
    • (2010) Science , vol.330 , pp. 460-461
    • Rappaport, S.M.1    Smith, M.T.2
  • 62
    • 77953886372 scopus 로고    scopus 로고
    • An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus
    • 10.1371/journal.pone.0010746, 2873978, 20505766
    • Patel CJ, Bhattacharya J, Butte AJ. An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. PLoS One 2010, 5:e10746. 10.1371/journal.pone.0010746, 2873978, 20505766.
    • (2010) PLoS One , vol.5
    • Patel, C.J.1    Bhattacharya, J.2    Butte, A.J.3
  • 64
    • 84888022733 scopus 로고    scopus 로고
    • Workshop on Emerging Technologies for Measuring Individual Expsomes
    • Workshop on Emerging Technologies for Measuring Individual Expsomes Emerging Science for Environmental Health Decisions. December 8-9, Washington, DC http://nas-sites.org/emergingscience/workshops/individual-exposomes/, Workshop on Emerging Technologies for Measuring Individual Expsomes.
    • Emerging Science for Environmental Health Decisions. December 8-9, Washington, DC
  • 65
    • 70349241725 scopus 로고    scopus 로고
    • Inflammatory phenotypes in adult asthma: clinical applications
    • 10.1111/j.1752-699X.2009.00162.x, 20298405
    • Gibson PG. Inflammatory phenotypes in adult asthma: clinical applications. Clin Respir J 2009, 3:198-206. 10.1111/j.1752-699X.2009.00162.x, 20298405.
    • (2009) Clin Respir J , vol.3 , pp. 198-206
    • Gibson, P.G.1
  • 67
    • 77950910419 scopus 로고    scopus 로고
    • Revealing strengths and weaknesses of methods for gene network inference
    • 10.1073/pnas.0913357107, 2851985, 20308593
    • Marbach D, Prill RJ, Schaffter T, Mattiussi C, Floreano D, Stolovitzky G. Revealing strengths and weaknesses of methods for gene network inference. Proc Natl Acad Sci USA 2010, 107:6286-6291. 10.1073/pnas.0913357107, 2851985, 20308593.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 6286-6291
    • Marbach, D.1    Prill, R.J.2    Schaffter, T.3    Mattiussi, C.4    Floreano, D.5    Stolovitzky, G.6
  • 68
    • 0033707946 scopus 로고    scopus 로고
    • Using Bayesian networks to analyze expression data
    • 10.1089/106652700750050961, 11108481
    • Friedman N, Linial M, Nachman I, Pe'er D. Using Bayesian networks to analyze expression data. J Comput Biol 2000, 7:601-620. 10.1089/106652700750050961, 11108481.
    • (2000) J Comput Biol , vol.7 , pp. 601-620
    • Friedman, N.1    Linial, M.2    Nachman, I.3    Pe'er, D.4
  • 69
    • 79952112313 scopus 로고    scopus 로고
    • Reconstructing transcriptional regulatory networks using three-way mutual information and Bayesian networks
    • 10.1007/978-1-60761-854-6_23, 20827604
    • Luo W, Woolf PJ. Reconstructing transcriptional regulatory networks using three-way mutual information and Bayesian networks. Methods Mol Biol 2010, 674:401-418. 10.1007/978-1-60761-854-6_23, 20827604.
    • (2010) Methods Mol Biol , vol.674 , pp. 401-418
    • Luo, W.1    Woolf, P.J.2
  • 70
    • 67650258730 scopus 로고    scopus 로고
    • Disentangling molecular relationships with a causal inference test
    • 3224661, 19473544
    • Millstein J, Zhang B, Zhu J, Schadt EE. Disentangling molecular relationships with a causal inference test. BMC Genet 2009, 10:23. 3224661, 19473544.
    • (2009) BMC Genet , vol.10 , pp. 23
    • Millstein, J.1    Zhang, B.2    Zhu, J.3    Schadt, E.E.4
  • 71
    • 79957872153 scopus 로고    scopus 로고
    • Inferring Boolean network structure via correlation
    • 10.1093/bioinformatics/btr166, 21471013
    • Maucher M, Kracher B, Kuhl M, Kestler HA. Inferring Boolean network structure via correlation. Bioinformatics 2011, 27:1529-1536. 10.1093/bioinformatics/btr166, 21471013.
    • (2011) Bioinformatics , vol.27 , pp. 1529-1536
    • Maucher, M.1    Kracher, B.2    Kuhl, M.3    Kestler, H.A.4
  • 72
    • 6044247613 scopus 로고    scopus 로고
    • A Boolean algorithm for reconstructing the structure of regulatory networks
    • 10.1016/j.ymben.2004.05.002, 15491862
    • Mehra S, Hu WS, Karypis G. A Boolean algorithm for reconstructing the structure of regulatory networks. Metab Eng 2004, 6:326-339. 10.1016/j.ymben.2004.05.002, 15491862.
    • (2004) Metab Eng , vol.6 , pp. 326-339
    • Mehra, S.1    Hu, W.S.2    Karypis, G.3
  • 73
    • 79951948526 scopus 로고    scopus 로고
    • A Boolean-based systems biology approach to predict novel genes associated with cancer: application to colorectal cancer
    • 10.1186/1752-0509-5-35, 3051904, 21352556
    • Nagaraj SH, Reverter A. A Boolean-based systems biology approach to predict novel genes associated with cancer: application to colorectal cancer. BMC Syst Biol 2011, 5:35. 10.1186/1752-0509-5-35, 3051904, 21352556.
    • (2011) BMC Syst Biol , vol.5 , pp. 35
    • Nagaraj, S.H.1    Reverter, A.2
  • 74
    • 78149461178 scopus 로고    scopus 로고
    • DREAM3: network inference using dynamic context likelihood of relatedness and the inferelator
    • 10.1371/journal.pone.0009803, 2842436, 20339551
    • Madar A, Greenfield A, Vanden-Eijnden E, Bonneau R. DREAM3: network inference using dynamic context likelihood of relatedness and the inferelator. PLoS One 2010, 5:e9803. 10.1371/journal.pone.0009803, 2842436, 20339551.
    • (2010) PLoS One , vol.5
    • Madar, A.1    Greenfield, A.2    Vanden-Eijnden, E.3    Bonneau, R.4
  • 76
  • 77
    • 80052176477 scopus 로고    scopus 로고
    • Quantitative utilization of prior biological knowledge in the Bayesian network modeling of gene expression data
    • Gao S, Wang X. Quantitative utilization of prior biological knowledge in the Bayesian network modeling of gene expression data. BMC Bioinforma 2011, 12:359.
    • (2011) BMC Bioinforma , vol.12 , pp. 359
    • Gao, S.1    Wang, X.2
  • 78
    • 84864946487 scopus 로고    scopus 로고
    • Integrating external biological knowledge in the construction of regulatory networks from time-series expression data
    • 10.1186/1752-0509-6-101, 3465231, 22898396
    • Lo K, Raftery AE, Dombek KM, Zhu J, Schadt EE, Bumgarner RE, Yeung KY. Integrating external biological knowledge in the construction of regulatory networks from time-series expression data. BMC Syst Biol 2012, 6:101. 10.1186/1752-0509-6-101, 3465231, 22898396.
    • (2012) BMC Syst Biol , vol.6 , pp. 101
    • Lo, K.1    Raftery, A.E.2    Dombek, K.M.3    Zhu, J.4    Schadt, E.E.5    Bumgarner, R.E.6    Yeung, K.Y.7
  • 79
    • 34247556038 scopus 로고    scopus 로고
    • Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations
    • 10.1371/journal.pcbi.0030069, 1851982, 17432931
    • Zhu J, Wiener MC, Zhang C, Fridman A, Minch E, Lum PY, Sachs JR, Schadt EE. Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations. PLoS Comput Biol 2007, 3:e69. 10.1371/journal.pcbi.0030069, 1851982, 17432931.
    • (2007) PLoS Comput Biol , vol.3
    • Zhu, J.1    Wiener, M.C.2    Zhang, C.3    Fridman, A.4    Minch, E.5    Lum, P.Y.6    Sachs, J.R.7    Schadt, E.E.8


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