Phenotypic anchoring of arsenic and cadmium toxicity in three hepatic-related cell systems reveals compound- and cell-specific selective up-regulation of stress protein expression: Implications for fingerprint profiling of cytotoxicity

Chemico-Biological Interactions

Volumn 161, Issue 3, 2006, Pages 251-261

  Gottschalg, Elke ^a   Moore, Nicholas E ^a   Ryan, Abigail K ^a   Travis, Lucy C ^a   Waller, Ruth C ^a   Pratt, Steven ^a   Atmaca, Mukadder ^a,b   Kind, Clive N ^c   Fry, Jeffrey R ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b DICLE UNIVERSITY   (Turkey)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Arsenic; Cadmium; Cytotoxicity; FGC4 cells; Heat shock proteins; HepG2 cells; Metallothionein; Phenotypic anchoring; Rat hepatocytes; Stress proteins

Indexed keywords

ARSENIC; CADMIUM; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; METALLOTHIONEIN; NEUTRAL RED;

ANIMAL CELL; ARTICLE; CELL TYPE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENOMICS; HUMAN; HUMAN CELL; LIVER CELL CULTURE; MALE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PROTEIN EXPRESSION; PROTEOMICS; RAT; UPREGULATION;

ANIMALS; ARSENIC; CADMIUM; CELL SURVIVAL; CELLS, CULTURED; DNA FINGERPRINTING; HEAT-SHOCK PROTEINS; HEPATOCYTES; HUMANS; LIVER NEOPLASMS; MALE; PHENOTYPE; RATS; RATS, WISTAR; UP-REGULATION;

EID: 33746260458     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2006.04.003     Document Type: Article

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