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Volumn 14, Issue 7, 2013, Pages 420-426

A TLR6 polymorphism is associated with increased risk of Legionnaires' disease

Author keywords

Legionella pneumophila; Legionnaires' disease; polymorphism; TLR6

Indexed keywords

TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6;

EID: 84886726374     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2013.34     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 11944258698 scopus 로고
    • New and emerging etiologies for community-acquired pneumonia with implications for therapy. A prospective multicenter study of 359 cases
    • Fang GD, Fine M, Orloff J, Arisumi D, Yu VL, Kapoor W et al. New and emerging etiologies for community-acquired pneumonia with implications for therapy. A prospective multicenter study of 359 cases. Medicine (Baltimore) 1990; 69: 307-316.
    • (1990) Medicine (Baltimore) , vol.69 , pp. 307-316
    • Fang, G.D.1    Fine, M.2    Orloff, J.3    Arisumi, D.4    Yu, V.L.5    Kapoor, W.6
  • 2
    • 77952458032 scopus 로고    scopus 로고
    • Clinical features and predictors of mortality in admitted patients with community- and hospital-acquired legionellosis: A Danish historical cohort study
    • Jespersen S, Søgaard OS, Schønheyder HC, Fine MJ, Østergaard L. Clinical features and predictors of mortality in admitted patients with community- and hospital-acquired legionellosis: A Danish historical cohort study. BMC Infect Dis 2010; 10: 124.
    • (2010) BMC Infect Dis , vol.10 , pp. 124
    • Jespersen, S.1    Søgaard, O.S.2    Schønheyder, H.C.3    Fine, M.J.4    Østergaard, L.5
  • 3
    • 0035059902 scopus 로고    scopus 로고
    • Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: Implications for management guidelines
    • Lim WS, Macfarlane JT, Boswell TC, Harrison TG, Rose D, Leinonen M et al. Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: Implications for management guidelines. Thorax 2001; 56: 296-301.
    • (2001) Thorax , vol.56 , pp. 296-301
    • Lim, W.S.1    Macfarlane, J.T.2    Boswell, T.C.3    Harrison, T.G.4    Rose, D.5    Leinonen, M.6
  • 4
    • 49449093755 scopus 로고    scopus 로고
    • Increasing incidence of legionellosis in the United States, 1990-2005 changing epidemiologic trends
    • Neil K, Berkelman R. Increasing incidence of legionellosis in the United States, 1990-2005: Changing epidemiologic trends. Clin Infect Dis 2008; 47: 591-599.
    • Clin Infect Dis , vol.2008 , Issue.47 , pp. 591-599
    • Neil, K.1    Berkelman, R.2
  • 6
    • 0036272487 scopus 로고    scopus 로고
    • Hospital-acquired legionellosis: Solutions for a preventable infection
    • Sabria M, Yu VL. Hospital-acquired legionellosis: Solutions for a preventable infection. Lancet Infect Dis 2002; 2: 368-373.
    • (2002) Lancet Infect Dis , vol.2 , pp. 368-373
    • Sabria, M.1    Yu, V.L.2
  • 7
    • 0025185498 scopus 로고
    • Nosocomial legionellosis
    • Hutchinson DN. Nosocomial legionellosis. Rev Med Micrbiol 1990; 1: 108-115.
    • (1990) Rev Med Micrbiol , vol.1 , pp. 108-115
    • Hutchinson, D.N.1
  • 8
    • 0033845771 scopus 로고    scopus 로고
    • Nosocomial legionellosis
    • Yu VL. Nosocomial legionellosis. Curr Opin Infect Dis 2000; 13: 385-388.
    • (2000) Curr Opin Infect Dis , vol.13 , pp. 385-388
    • Yu, V.L.1
  • 9
    • 0033198204 scopus 로고    scopus 로고
    • Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by Toll-like receptor 2
    • Hirschfeld M, Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM et al. Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by Toll-like receptor 2. J Immunol 1999; 163: 2382-2386.
    • (1999) J Immunol , vol.163 , pp. 2382-2386
    • Hirschfeld, M.1    Kirschning, C.J.2    Schwandner, R.3    Wesche, H.4    Weis, J.H.5    Wooten, R.M.6
  • 10
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 11
    • 0037439663 scopus 로고    scopus 로고
    • Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2
    • Girard R, Pedron T, Uematsu S, Balloy V, Chignard M, Akira S et al. Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2. J Cell Sci 2003; 116(Pt 2): 293-302.
    • (2003) J Cell Sci , vol.116 , Issue.PART 2 , pp. 293-302
    • Girard, R.1    Pedron, T.2    Uematsu, S.3    Balloy, V.4    Chignard, M.5    Akira, S.6
  • 12
    • 0035879283 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling
    • Bulut Y, Faure E, Thomas L, Equils O, Arditi M. Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. J Immunol 2001; 167: 987-994.
    • (2001) J Immunol , vol.167 , pp. 987-994
    • Bulut, Y.1    Faure, E.2    Thomas, L.3    Equils, O.4    Arditi, M.5
  • 16
    • 11144338200 scopus 로고    scopus 로고
    • Differential roles of Toll-like receptors 2 and 4 in in vitro responses of macrophages to Legionella pneumophila
    • Akamine M, Higa F, Arakaki N, Kawakami K, Takeda K, Akira S et al. Differential roles of Toll-like receptors 2 and 4 in in vitro responses of macrophages to Legionella pneumophila. Infect Immun 2005; 73: 352-361.
    • (2005) Infect Immun , vol.73 , pp. 352-361
    • Akamine, M.1    Higa, F.2    Arakaki, N.3    Kawakami, K.4    Takeda, K.5    Akira, S.6
  • 17
    • 33744782563 scopus 로고    scopus 로고
    • Myeloid differentiation primary response gene (88)- and toll-like receptor 2-deficient mice are susceptible to infection with aerosolized Legionella pneumophila
    • Hawn TR, Smith KD, Aderem A, Skerrett SJ. Myeloid differentiation primary response gene (88)- and toll-like receptor 2-deficient mice are susceptible to infection with aerosolized Legionella pneumophila. J Infect Dis 2006; 193: 1693-1702.
    • (2006) J Infect Dis , vol.193 , pp. 1693-1702
    • Hawn, T.R.1    Smith, K.D.2    Aderem, A.3    Skerrett, S.J.4
  • 18
    • 33646948879 scopus 로고    scopus 로고
    • MyD88-dependent responses involving toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease
    • Archer KA, Roy CR. MyD88-dependent responses involving toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease. Infect Immun 2006; 74: 3325-3333.
    • (2006) Infect Immun , vol.74 , pp. 3325-3333
    • Archer, K.A.1    Roy, C.R.2
  • 19
    • 33847684773 scopus 로고    scopus 로고
    • Role of Tolllike receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model
    • Fuse ET, Tateda K, Kikuchi Y, Matsumoto T, Gondaira F, Azuma A et al. Role of Tolllike receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model. J Med Microbiol 2007; 56(Pt 3): 305-312.
    • (2007) J Med Microbiol , vol.56 , Issue.PART 3 , pp. 305-312
    • Fuse, E.T.1    Tateda, K.2    Kikuchi, Y.3    Matsumoto, T.4    Gondaira, F.5    Azuma, A.6
  • 20
    • 39549123040 scopus 로고    scopus 로고
    • Toll-like receptor polymorphisms and susceptibility to human disease
    • Misch EA, Hawn TR. Toll-like receptor polymorphisms and susceptibility to human disease. Clin Sci (Lond) 2008; 114: 347-360.
    • (2008) Clin Sci (Lond) , vol.114 , pp. 347-360
    • Misch, E.A.1    Hawn, T.R.2
  • 21
    • 34250205895 scopus 로고    scopus 로고
    • Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy
    • Johnson CM, Lyle EA, Omueti KO, Stepensky VA, Yegin O, Alpsoy E et al. Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy. J Immunol 2007; 178: 7520-7524.
    • (2007) J Immunol , vol.178 , pp. 7520-7524
    • Johnson, C.M.1    Lyle, E.A.2    Omueti, K.O.3    Stepensky, V.A.4    Yegin, O.5    Alpsoy, E.6
  • 22
    • 34547409225 scopus 로고    scopus 로고
    • A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis
    • Thuong NTT, Hawn TR, Thwaites GE, Chau TTH, Lan NTN, Quy HT et al. A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis. Genes Immun 2007; 8: 422-428.
    • (2007) Genes Immun , vol.8 , pp. 422-428
    • Thuong, N.T.T.1    Hawn, T.R.2    Thwaites, G.E.3    Chau, T.T.H.4    Lan, N.T.N.5    Quy, H.T.6
  • 23
    • 14044259411 scopus 로고    scopus 로고
    • Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
    • Hawn TR, Verbon A, Janer M, Zhao LP, Beutler B, Aderem A. Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci USA 2005; 102: 2487-2489.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2487-2489
    • Hawn, T.R.1    Verbon, A.2    Janer, M.3    Zhao, L.P.4    Beutler, B.5    Aderem, A.6
  • 24
    • 10744226016 scopus 로고    scopus 로고
    • A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to Legionnaires' disease
    • Hawn TR, Verbon A, Lettinga KD, Zhao LP, Li SS, Laws RJ et al. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to Legionnaires' disease. J Exp Med 2003; 198: 1563-1572.
    • (2003) J Exp Med , vol.198 , pp. 1563-1572
    • Hawn, T.R.1    Verbon, A.2    Lettinga, K.D.3    Zhao, L.P.4    Li, S.S.5    Laws, R.J.6
  • 25
    • 67650105333 scopus 로고    scopus 로고
    • Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women
    • Hawn TR, Scholes D, Li SS, Wang H, Yang Y, Roberts PL et al. Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women. PLoS One 2009; 4: E5990.
    • (2009) PLoS One , vol.4
    • Hawn, T.R.1    Scholes, D.2    Li, S.S.3    Wang, H.4    Yang, Y.5    Roberts, P.L.6
  • 26
    • 34547868501 scopus 로고    scopus 로고
    • A common human TLR1 polymorphism regulates the innate immune response to lipopeptides
    • Hawn TR, Misch EA, Dunstan SJ, Thwaites GE, Lan NT, Quy HT et al. A common human TLR1 polymorphism regulates the innate immune response to lipopeptides. Eur J Immunol 2007; 37: 2280-2289.
    • (2007) Eur J Immunol , vol.37 , pp. 2280-2289
    • Hawn, T.R.1    Misch, E.A.2    Dunstan, S.J.3    Thwaites, G.E.4    Lan, N.T.5    Quy, H.T.6
  • 27
    • 48949118047 scopus 로고    scopus 로고
    • Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction
    • Misch EA, Macdonald M, Ranjit C, Sapkota BR, Wells RD, Siddiqui MR et al. Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction. PLoS Negl Trop Dis 2008; 2: E231.
    • (2008) PLoS Negl Trop Dis , vol.2
    • Misch, E.A.1    Macdonald, M.2    Ranjit, C.3    Sapkota, B.R.4    Wells, R.D.5    Siddiqui, M.R.6
  • 30
    • 78650903053 scopus 로고    scopus 로고
    • Progress in the surveillance and control of legionella infection in france, rfpy1 1998 ì2008
    • Campèse C, Bitar D, Jarraud S, Maine C, Forey Fo, Etienne J et al. Progress in the surveillance and control of Legionella infection in France, 1998-ì2008. Int J Infect Dis 2011; 15: E30-e37.
    • (2011) Int J Infect Dis , vol.15
    • Campèse, C.1    Bitar, D.2    Jarraud, S.3    Maine, C.4    Forey, F.5    Etienne, J.6
  • 32
    • 72149088217 scopus 로고    scopus 로고
    • The relationship between diagnostic tests and case characteristics in Legionnaires' disease
    • Jespersen S, Søgaard OS, Fine MJ, Østergaard L. The relationship between diagnostic tests and case characteristics in Legionnaires' disease. Scand J Infect Dis 2009; 41: 425-432.
    • (2009) Scand J Infect Dis , vol.41 , pp. 425-432
    • Jespersen, S.1    Søgaard, O.S.2    Fine, M.J.3    Østergaard, L.4
  • 34
    • 77951601179 scopus 로고    scopus 로고
    • Induction of human beta-defensin-2 in pulmonary epithelial cells by Legionella pneumophila: Involvement of TLR2 and TLR5, p38 MAPK, JNK, NF-kB, and AP-1
    • Scharf S, Hippenstiel S, Flieger A, Suttorp N, N'Guessan PD. Induction of human beta-defensin-2 in pulmonary epithelial cells by Legionella pneumophila: Involvement of TLR2 and TLR5, p38 MAPK, JNK, NF-kB, and AP-1. Am J Physiol Lung Cell Mol Physiol 2010; 298: L687-L695.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298
    • Scharf, S.1    Hippenstiel, S.2    Flieger, A.3    Suttorp, N.4    N'Guessan, P.D.5
  • 35
    • 84886729254 scopus 로고    scopus 로고
    • The genetics and immunology of host resistance to Legionella infection
    • In Heuner K, Swanson M (eds) Caister Academic Press: Ann Arbor, MI, USA
    • Vance R, Hawn TR. The genetics and immunology of host resistance to Legionella infection. In: Heuner K, Swanson M (eds) Legionella: Molecular Microbiology. Caister Academic Press: Ann Arbor, MI, USA, 2008.
    • (2008) Legionella: Molecular Microbiology
    • Vance, R.1    Hawn, T.R.2
  • 36
    • 19044386832 scopus 로고    scopus 로고
    • Legionella pneumophila mediated activation of dendritic cells involves CD14 and TLR2
    • Braedel-Ruoff S, Faigle M, Hilf N, Neumeister B, Schild H. Legionella pneumophila mediated activation of dendritic cells involves CD14 and TLR2. J Endotoxin Res 2005; 11: 89-96.
    • (2005) J Endotoxin Res , vol.11 , pp. 89-96
    • Braedel-Ruoff, S.1    Faigle, M.2    Hilf, N.3    Neumeister, B.4    Schild, H.5
  • 37
    • 70350728797 scopus 로고    scopus 로고
    • Legionella lipoprotein activates toll-like receptor 2 and induces cytokine production and expression of costimulatory molecules in peritoneal macrophages
    • Shim HK, Kim JY, Kim MJ, Sim HS, Park DW, Sohn JW. Legionella lipoprotein activates toll-like receptor 2 and induces cytokine production and expression of costimulatory molecules in peritoneal macrophages. Exp Mol Med 2009; 41: 687-694.
    • (2009) Exp Mol Med , vol.41 , pp. 687-694
    • Shim, H.K.1    Kim, J.Y.2    Kim, M.J.3    Sim, H.S.4    Park, D.W.5    Sohn, J.W.6
  • 38
    • 42949132877 scopus 로고    scopus 로고
    • Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease
    • Ma X, Liu Y, Gowen BB, Graviss EA, Clark AG, Musser JM. Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease. PLoS One 2007; 2: E1318.
    • (2007) PLoS One , vol.2
    • Ma, X.1    Liu, Y.2    Gowen, B.B.3    Graviss, E.A.4    Clark, A.G.5    Musser, J.M.6
  • 39
    • 33745492610 scopus 로고    scopus 로고
    • TLR1 and TLR6 polymorphisms are associated with susceptibility to invasive aspergillosis after allogeneic stem cell transplantation
    • Kesh S, Mensah NY, Peterlongo P, Jaffe D, Hsu K, Van Den Brink M et al. TLR1 and TLR6 polymorphisms are associated with susceptibility to invasive aspergillosis after allogeneic stem cell transplantation. Ann N Y Acad Sci 2005; 1062: 95-103.
    • (2005) Ann N Y Acad Sci , vol.1062 , pp. 95-103
    • Kesh, S.1    Mensah, N.Y.2    Peterlongo, P.3    Jaffe, D.4    Hsu, K.5    Van Den Brink, M.6
  • 40
    • 77958153817 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion
    • Shey MS, Randhawa AK, Bowmaker M, Smith E, Scriba TJ, de Kock M et al. Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion. Genes Immun 2010; 11: 561-572.
    • (2010) Genes Immun , vol.11 , pp. 561-572
    • Shey, M.S.1    Randhawa, A.K.2    Bowmaker, M.3    Smith, E.4    Scriba, T.J.5    De Kock, M.6
  • 41
    • 0034610291 scopus 로고    scopus 로고
    • The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
    • Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB et al. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors. Proc Natl Acad Sci USA 2000; 97: 13766-13771.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13766-13771
    • Ozinsky, A.1    Underhill, D.M.2    Fontenot, J.D.3    Hajjar, A.M.4    Smith, K.D.5    Wilson, C.B.6
  • 42
    • 37549043217 scopus 로고    scopus 로고
    • Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
    • Sanjuan MA, Dillon CP, Tait SWG, Moshiach S, Dorsey F, Connell S et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 2007; 450: 1253-1257.
    • (2007) Nature , vol.450 , pp. 1253-1257
    • Sanjuan, M.A.1    Dillon, C.P.2    Tait, S.W.G.3    Moshiach, S.4    Dorsey, F.5    Connell, S.6
  • 43
    • 0035165287 scopus 로고    scopus 로고
    • Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin
    • Hajjar AM, O'Mahony DS, Ozinsky A, Underhill DM, Aderem A, Klebanoff SJ et al. Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin. J Immunol 2001; 166: 15-19.
    • (2001) J Immunol , vol.166 , pp. 15-19
    • Hajjar, A.M.1    O'Mahony, D.S.2    Ozinsky, A.3    Underhill, D.M.4    Aderem, A.5    Klebanoff, S.J.6


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