Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease

PLoS ONE

Volumn 2, Issue 12, 2007, Pages

  Ma, Xin ^a   Liu, Yuhua ^b,e   Gowen, Brian B ^b,f   Graviss, Edward A ^a   Clark, Andrew G ^c   Musser, James M ^b,d  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Department of Obstetrics Gynecology   (United States)

^d HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f UTAH STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIMYCOBACTERIAL AGENT; GENOMIC DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 6;

ADULT; AFRICAN AMERICAN; AMINO ACID SEQUENCE; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE TRANSMISSION; ETHNIC DIFFERENCE; EXON; EXTRAPULMONARY TUBERCULOSIS; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETIC VARIABILITY; HAPLOTYPE; HOMOZYGOTE; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; INFECTION RISK; INNATE IMMUNITY; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; POPULATION BASED CASE CONTROL STUDY; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TUBERCULOSIS; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; MIDDLE AGED; MOLECULAR GENETICS; MULTIGENE FAMILY; MYCOBACTERIUM TUBERCULOSIS; SITE DIRECTED MUTAGENESIS;

ADULT; CASE-CONTROL STUDIES; EXONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; TOLL-LIKE RECEPTORS; TUBERCULOSIS;

EID: 42949132877     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001318     Document Type: Article

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