Clinical features and predictors of mortality in admitted patients with community- and hospital-acquired legionellosis: A Danish historical cohort study

BMC Infectious Diseases

Volumn 10, Issue , 2010, Pages

  Jespersen, Sanne ^a   Søgaard, Ole S ^a   Schønheyder, Henrik C ^a   Fine, Michael J ^b,c   Østergaard, Lars ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROLIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; TETRACYCLINE;

ADULT; AGE DISTRIBUTION; AGED; ANTIBIOTIC THERAPY; ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; COMMUNICABLE DISEASE; COMORBIDITY; CONTROLLED STUDY; DENMARK; DISEASE DURATION; FATALITY; FEMALE; HEALTH SURVEY; HIGH RISK PATIENT; HOSPITAL INFECTION; HUMAN; LABORATORY TEST; LEGIONNAIRE DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROGNOSIS; CROSS INFECTION; HOSPITALIZATION; ISOLATION AND PURIFICATION; LEGIONELLA; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY;

AGED; COHORT STUDIES; COMMUNITY-ACQUIRED INFECTIONS; CROSS INFECTION; DENMARK; FEMALE; HOSPITALIZATION; HUMANS; LEGIONELLA; LEGIONELLOSIS; MALE; MIDDLE AGED; PROGNOSIS;

EID: 77952458032     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-10-124     Document Type: Article

References (21)

1. Fields BS, Benson RF, Besser RE. Legionella and Legionnaires' disease: 25 years of investigation. Clin Microbiol Rev 2002, 15(3):506-26. 10.1128/CMR.15.3.506-526.2002, 118082, 12097254.
2. Neil K, Berkelman R. Increasing incidence of legionellosis in the United States, 1990-2005: changing epidemiologic trends. Clin Infect Dis 2008, 47(5):591-9. 10.1086/590557, 18665818.
3. Dedicoat M, Venkatesan P. The treatment of Legionnaires' disease. J Antimicrob Chemother 1999, 43(6):747-52. 10.1093/jac/43.6.747, 10404312.
4. Vergis EN, Indorf A, File TM, et al. Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. Arch Intern Med 2000, 160(9):1294-300. 10.1001/archinte.160.9.1294, 10809032.
5. Dournon E, Mayaud C, Wolff M, et al. Comparison of the activity of three antibiotic regimens in severe Legionnaires' disease. J Antimicrob Chemother 1990, 26(Suppl B):129-39.
6. Cunha BA. Clinical features of legionnaires' disease. Semin Respir Infect 1998, 13(2):116-27.
7. Strampfer MJ, Cunha BA. Clinical and laboratory aspects of Legionnaire's disease. Smin Respir Infect 1987, 2(4):228-34.
8. Sopena N, Sabria-Leal M, Pedro-Botet ML, et al. Comparative study of the clinical presentation of Legionella pneumonia and other community-acquired pneumonias. Chest 1998, 113(5):1195-200. 10.1378/chest.113.5.1195, 9596294.
9. Heath CH, Grove DI, Looke DF. Delay in appropriate therapy of Legionella pneumonia associated with increased mortality. Eur J Clin Microbiol Infect Dis 1996, 15(4):286-90. 10.1007/BF01695659, 8781878.
10. Gacouin A, Le Tulzo Y, Lavoue S, et al. Severe pneumonia due to Legionella pneumophila: prognostic factors, impact of delayed appropriate antimicrobial therapy. Intensive Care Med 2002, 28(6):686-91. 10.1007/s00134-002-1304-8, 12107671.
11. el-Ebiary M, Sarmiento X, Torres A, et al. Prognostic factors of severe Legionella pneumonia requiring admission to ICU. Am J Respir Crit Care Med 1997, 156(5):1467-72.
12. Danmarks statistik. , http://www.statistikbanken.dk/BEF1A
13. Jespersen S, Sogaard OS, Fine MJ, Ostergaard L. The relationship between diagnostic tests and case characteristics in Legionnaires' disease. Scand J Infect Dis 2009, 8:1-8.
14. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987, 40(5):373-83. 10.1016/0021-9681(87)90171-8, 3558716.
15. de Groot V, Beckerman H, Lankhorst GJ, Bouter LM. How to measure comorbidity. a critical review of available methods. J Clin Epidemiol 2003, 56(3):221-9. 10.1016/S0895-4356(02)00585-1, 12725876.
16. Lim WS, Eerden MM, Laing R, et al. Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax 2003, 58(5):377-82. 10.1136/thorax.58.5.377, 1746657, 12728155.
17. Fine MJ, Auble TE, Yealy DM, et al. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 1997, 336(4):243-50. 10.1056/NEJM199701233360402, 8995086.
18. Helms CM, Viner JP, Weisenburger DD, Chiu LC, Renner ED, Johnson W. Sporadic Legionnaires' disease: clinical observations on 87 nosocomial and community-acquired cases. Am J Med Sci 1984, 288(1):2-12. 10.1097/00000441-198407000-00001, 6465187.
19. Pedro-Botet ML, Sabria-Leal M, Haro M, et al. Nosocomial and community-acquired Legionella pneumonia: clinical comparative analysis. Eur Respir J 1995, 8(11):1929-33. 10.1183/09031936.95.08111929, 8620964.
20. Benin AL, Benson RF, Besser RE. Trends in legionnaires disease, 1980-1998: declining mortality and new patterns of diagnosis. Clin Infect Dis 2002, 35(9):1039-46. 10.1086/342903, 12384836.
21. Marston BJ, Lipman HB, Breiman RF. Surveillance for Legionnaires' disease. Risk factors for morbidity and mortality. Arch Intern Med 1994, 154(21):2417-22. 10.1001/archinte.154.21.2417, 7979837.