Structural mechanism of replication stalling on a bulky amino-polycyclic aromatic hydrocarbon DNA adduct by a y family DNA polymerase

Journal of Molecular Biology

Volumn 425, Issue 22, 2013, Pages 4167-4176

  Kirouac, Kevin N ^a   Basu, Ashis K ^b   Ling, Hong ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

DNA damage; environmental pollution; polycyclic aromatic hydrocarbons; translesion DNA replication; Y family polymerase

Indexed keywords

AMINE; DEOXYGUANOSINE DERIVATIVE; DNA POLYMERASE; DNA POLYMERASE DPO4; N [DEOXYGUANOSINE 8 YL] 1 AMINOPYRENE; NITRO DERIVATIVE; NUCLEOTIDE; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE DERIVATIVE; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DNA ADDUCT; DNA CONFORMATION; DNA HELIX; DNA REPLICATION; DNA STRAND; DNA STRUCTURE; DNA TEMPLATE; ENZYME ACTIVE SITE; HYDROPHOBICITY; INTERCALATION COMPLEX; METABOLISM; MOLECULAR STABILITY; POLLUTION; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 84886721590     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.07.020     Document Type: Article

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