-
2
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville, S., and Hall, A. (2002) Rho GTPases in cell biology. Nature 420, 629-635
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
3
-
-
27944479854
-
Rho GTPases. Biochemistry and biology
-
Jaffe, A. B., and Hall, A. (2005) Rho GTPases. Biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21, 247-269
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 247-269
-
-
Jaffe, A.B.1
Hall, A.2
-
4
-
-
50149083752
-
Mammalian Rho GTPases. New insights into their functions from in vivo studies
-
Heasman, S. J., and Ridley, A. J. (2008) Mammalian Rho GTPases. New insights into their functions from in vivo studies. Nat. Rev. Mol. Cell Biol. 9, 690-701
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
5
-
-
0037213689
-
Rho GTPase-activating proteins in cell regulation
-
Moon, S. Y., and Zheng, Y. (2003) Rho GTPase-activating proteins in cell regulation. Trends Cell Biol. 13, 13-22
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 13-22
-
-
Moon, S.Y.1
Zheng, Y.2
-
6
-
-
77953145912
-
Spatio-temporal Rho GTPase signaling. Where are we now?
-
Pertz, O. (2010) Spatio-temporal Rho GTPase signaling. Where are we now? J. Cell Sci. 123, 1841-1850
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1841-1850
-
-
Pertz, O.1
-
7
-
-
79960706295
-
The "invisible hand." Regulation of RHO GTPases by RHOGDIs
-
Garcia-Mata, R., Boulter, E., and Burridge, K. (2011) The "invisible hand." Regulation of RHO GTPases by RHOGDIs. Nat. Rev. Mol. Cell Biol. 12, 493-504
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 493-504
-
-
Garcia-Mata, R.1
Boulter, E.2
Burridge, K.3
-
8
-
-
34648844192
-
Taking Rho GT-Pases to the next level. The cellular functions of atypical Rho GTPases
-
Aspenström, P., Ruusala, A., and Pacholsky, D. (2007) Taking Rho GT-Pases to the next level. The cellular functions of atypical Rho GTPases. Exp. Cell Res. 313, 3673-3679
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 3673-3679
-
-
Aspenström, P.1
Ruusala, A.2
Pacholsky, D.3
-
9
-
-
84856531511
-
Off the beaten paths. Alternative and crosstalk regulationof Rho GTPases
-
Boulter, E., Estrach, S., Garcia-Mata, R., and Féral, C. C. (2012) Off the beaten paths. Alternative and crosstalk regulationof Rho GTPases. FASEB J. 26, 469-479
-
(2012)
FASEB J.
, vol.26
, pp. 469-479
-
-
Boulter, E.1
Estrach, S.2
Garcia-Mata, R.3
Féral, C.C.4
-
10
-
-
54449089270
-
Rho family GTPase modification and dependence on CAAX motif-signaled posttranslational modification
-
Roberts, P. J., Mitin, N., Keller, P. J., Chenette, E. J., Madigan, J. P., Currin, R. O., Cox, A. D., Wilson, O., Kirschmeier, P., and Der, C. J. (2008) Rho family GTPase modification and dependence on CAAX motif-signaled posttranslational modification.. J. Biol. Chem. 283, 25150-25163
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 25150-25163
-
-
Roberts, P.J.1
Mitin, N.2
Keller, P.J.3
Chenette, E.J.4
Madigan, J.P.5
Currin, R.O.6
Cox, A.D.7
Wilson, O.8
Kirschmeier, P.9
Der, C.J.10
-
11
-
-
77953162073
-
Focaladhesion targeting links caveolin-1 to a Rac1-degradation pathway
-
Nethe, M., Anthony, E. C., Fernandez-Borja, M., Dee, R., Geerts, D., Hensbergen, P. J., Deelder, A. M., Schmidt, G., and Hordijk, P. L. (2010) Focaladhesion targeting links caveolin-1 to a Rac1-degradation pathway. J. Cell Sci. 123, 1948-1958
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1948-1958
-
-
Nethe, M.1
Anthony, E.C.2
Fernandez-Borja, M.3
Dee, R.4
Geerts, D.5
Hensbergen, P.J.6
Deelder, A.M.7
Schmidt, G.8
Hordijk, P.L.9
-
12
-
-
0032489841
-
A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion
-
Nobes, C. D., Lauritzen, I., Mattei, M. G., Paris, S., Hall, A., and Chardin, P. (1998) A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion.. J. Cell Biol. 141, 187-197
-
(1998)
J. Cell Biol.
, vol.141
, pp. 187-197
-
-
Nobes, C.D.1
Lauritzen, I.2
Mattei, M.G.3
Paris, S.4
Hall, A.5
Chardin, P.6
-
13
-
-
33644843642
-
Function and regulation of Rnd proteins
-
Chardin, P. (2006) Function and regulation of Rnd proteins. Nat. Rev. Mol. Cell Biol. 7, 54-62
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 54-62
-
-
Chardin, P.1
-
14
-
-
44449178868
-
Rho GTPases in cancer cell biology
-
Vega, F. M., and Ridley, A. J. (2008) Rho GTPases in cancer cell biology. FEBS Lett. 582, 2093-2101
-
(2008)
FEBS Lett.
, vol.582
, pp. 2093-2101
-
-
Vega, F.M.1
Ridley, A.J.2
-
15
-
-
77958198472
-
Rnd proteins. Multifunctional regulators of the cytoskeleton and cell cycle progression
-
Riou, P., Villalonga, P., and Ridley, A. J. (2010) Rnd proteins. Multifunctional regulators of the cytoskeleton and cell cycle progression. Bioessays 32, 986-992
-
(2010)
Bioessays
, vol.32
, pp. 986-992
-
-
Riou, P.1
Villalonga, P.2
Ridley, A.J.3
-
16
-
-
0029894664
-
Identification of a novel human Rho protein with unusual properties. GTPase deficiency and in vivo farnesylation
-
Foster, R., Hu, K. Q., Lu, Y., Nolan, K. M., Thissen, J., and Settleman, J. (1996) Identification of a novel human Rho protein with unusual properties. GTPase deficiency and in vivo farnesylation. Mol. Cell. Biol. 16, 2689-2699
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2689-2699
-
-
Foster, R.1
Hu, K.Q.2
Lu, Y.3
Nolan, K.M.4
Thissen, J.5
Settleman, J.6
-
17
-
-
0031877714
-
RhoE regulates actin cytoskeleton organization and cell migration
-
Guasch, R. M., Scambler, P., Jones, G. E., and Ridley, A. J. (1998) RhoE regulates actin cytoskeleton organization and cell migration. Mol. Cell. Biol. 18, 4761-4771
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4761-4771
-
-
Guasch, R.M.1
Scambler, P.2
Jones, G.E.3
Ridley, A.J.4
-
18
-
-
0038655599
-
RhoE binds to ROCK I and inhibits downstream signaling
-
Riento, K., Guasch, R. M., Garg, R., Jin, B., and Ridley, A. J. (2003) RhoE binds to ROCK I and inhibits downstream signaling. Mol. Cell. Biol. 23, 4219-4229
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4219-4229
-
-
Riento, K.1
Guasch, R.M.2
Garg, R.3
Jin, B.4
Ridley, A.J.5
-
19
-
-
0038686581
-
Rnd proteins function as RhoA antagonists by activating p190 RhoGAP
-
Wennerberg, K., Forget, M. A., Ellerbroek, S. M., Arthur, W. T., Burridge, K., Settleman, J., Der, C. J., and Hansen, S. H. (2003) Rnd proteins function as RhoA antagonists by activating p190 RhoGAP. Curr. Biol. 13, 1106-1115
-
(2003)
Curr. Biol.
, vol.13
, pp. 1106-1115
-
-
Wennerberg, K.1
Forget, M.A.2
Ellerbroek, S.M.3
Arthur, W.T.4
Burridge, K.5
Settleman, J.6
Der, C.J.7
Hansen, S.H.8
-
20
-
-
23944518729
-
Small G-protein RhoE is underexpressed in prostate cancer and induces cell cycle arrest and apoptosis
-
Bektic, J., Pfeil, K., Berger, A. P., Ramoner, R., Pelzer, A., Schäfer, G., Kofler, K., Bartsch, G., and Klocker, H. (2005) Small G-protein RhoE is underexpressed in prostate cancer and induces cell cycle arrest and apoptosis.. Prostate 64, 332-340
-
(2005)
Prostate
, vol.64
, pp. 332-340
-
-
Bektic, J.1
Pfeil, K.2
Berger, A.P.3
Ramoner, R.4
Pelzer, A.5
Schäfer, G.6
Kofler, K.7
Bartsch, G.8
Klocker, H.9
-
21
-
-
33846661640
-
RhoE interferes with Rb inactivation and regulates the proliferation and survival of the U87 human glioblastoma cell line
-
Poch, E., Miñambres, R., Mocholí, E., Ivorra, C., Pérez-Aragó, A., Guerri, C., Pérez-Roger, I., and Guasch, R. M. (2007) RhoE interferes with Rb inactivation and regulates the proliferation and survival of the U87 human glioblastoma cell line.. Exp. Cell Res. 313, 719-731
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 719-731
-
-
Poch, E.1
Miñambres, R.2
Mocholí, E.3
Ivorra, C.4
Pérez-Aragó, A.5
Guerri, C.6
Pérez-Roger, I.7
Guasch, R.M.8
-
22
-
-
4444355324
-
RhoE inhibits cell cycle progression and Ras-induced transformation
-
Villalonga, P., Guasch, R. M., Riento, K., and Ridley, A. J. (2004) RhoE inhibits cell cycle progression and Ras-induced transformation. Mol. Cell. Biol. 24, 7829-7840
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7829-7840
-
-
Villalonga, P.1
Guasch, R.M.2
Riento, K.3
Ridley, A.J.4
-
23
-
-
84868099035
-
RhoE functions as a tumor suppressor in esophageal squamous cell carcinoma and modulates the PTEN/PI3K/Akt signaling pathway
-
Zhao, H., Yang, J., Fan, T., Li, S., and Ren, X. (2012) RhoE functions as a tumor suppressor in esophageal squamous cell carcinoma and modulates the PTEN/PI3K/Akt signaling pathway.. Tumour Biol. 33, 1363-1374
-
(2012)
Tumour Biol.
, vol.33
, pp. 1363-1374
-
-
Zhao, H.1
Yang, J.2
Fan, T.3
Li, S.4
Ren, X.5
-
24
-
-
33845420563
-
RhoE is a prosurvival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress
-
Ongusaha, P. P., Kim, H. G., Boswell, S. A., Ridley, A. J., Der, C. J., Dotto, G. P., Kim, Y. B., Aaronson, S. A., and Lee, S. W. (2006) RhoE is a prosurvival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress.. Curr. Biol. 16, 2466-2472
-
(2006)
Curr. Biol.
, vol.16
, pp. 2466-2472
-
-
Ongusaha, P.P.1
Kim, H.G.2
Boswell, S.A.3
Ridley, A.J.4
Der, C.J.5
Dotto, G.P.6
Kim, Y.B.7
Aaronson, S.A.8
Lee, S.W.9
-
25
-
-
33947499358
-
The protective role of a small GTPase RhoE against UVB-induced DNA damage in keratinocytes
-
Boswell, S. A., Ongusaha, P. P., Nghiem, P., and Lee, S. W. (2007) The protective role of a small GTPase RhoE against UVB-induced DNA damage in keratinocytes. J. Biol. Chem. 282, 4850-4858
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4850-4858
-
-
Boswell, S.A.1
Ongusaha, P.P.2
Nghiem, P.3
Lee, S.W.4
-
26
-
-
79955736859
-
RhoE deficiency produces postnatal lethality, profound motor deficits and neurodevelopmental delay in mice
-
Mocholí, E., Ballester-Lurbe, B., Arqué, G., Poch, E., Peris, B., Guerri, C., Dierssen, M., Guasch, R. M., Terrado, J., and Pérez-Roger, I. (2011) RhoE deficiency produces postnatal lethality, profound motor deficits and neurodevelopmental delay in mice.. PLoS One 6, e19236
-
(2011)
PLoS One
, vol.6
-
-
Mocholí, E.1
Ballester-Lurbe, B.2
Arqué, G.3
Poch, E.4
Peris, B.5
Guerri, C.6
Dierssen, M.7
Guasch, R.M.8
Terrado, J.9
Pérez-Roger, I.10
-
27
-
-
79952763999
-
Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling
-
Pacary, E., Heng, J., Azzarelli, R., Riou, P., Castro, D., Lebel-Potter, M., Parras, C., Bell, D. M., Ridley, A. J., Parsons, M., and Guillemot, F. (2011) Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling.. Neuron 69, 1069-1084
-
(2011)
Neuron
, vol.69
, pp. 1069-1084
-
-
Pacary, E.1
Heng, J.2
Azzarelli, R.3
Riou, P.4
Castro, D.5
Lebel-Potter, M.6
Parras, C.7
Bell, D.M.8
Ridley, A.J.9
Parsons, M.10
Guillemot, F.11
-
28
-
-
84862022750
-
Neuronal polarization is impaired in mice lacking RhoE expression
-
Peris, B., Gonzalez-Granero, S., Ballester-Lurbe, B., García-Verdugo, J. M., Pérez-Roger, I., Guerri, C., Terrado, J., and Guasch, R. M. (2012) Neuronal polarization is impaired in mice lacking RhoE expression. J. Neurochem. 121, 903-914
-
(2012)
J. Neurochem.
, vol.121
, pp. 903-914
-
-
Peris, B.1
Gonzalez-Granero, S.2
Ballester-Lurbe, B.3
García-Verdugo, J.M.4
Pérez-Roger, I.5
Guerri, C.6
Terrado, J.7
Guasch, R.M.8
-
29
-
-
38849185196
-
PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE
-
Pinner, S., and Sahai, E. (2008) PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. Nat. Cell Biol. 10, 127-137
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 127-137
-
-
Pinner, S.1
Sahai, E.2
-
30
-
-
78650512223
-
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
-
Hidalgo-Carcedo, C., Hooper, S., Chaudhry, S. I., Williamson, P., Harrington, K., Leitinger, B., and Sahai, E. (2011) Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.. Nat. Cell Biol. 13, 49-58
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 49-58
-
-
Hidalgo-Carcedo, C.1
Hooper, S.2
Chaudhry, S.I.3
Williamson, P.4
Harrington, K.5
Leitinger, B.6
Sahai, E.7
-
31
-
-
78649771814
-
Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells
-
Belgiovine, C, Frapolli, R., Bonezzi, K., Chiodi, I., Favero, F., Mello-Grand, M., Dei Tos, A. P., Giulotto, E., Taraboletti, G., D'Incalci, M., and Mondello, C. (2010) Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells.. PLoS One 5, e14154
-
(2010)
PLoS One
, vol.5
-
-
Belgiovine, C.1
Frapolli, R.2
Bonezzi, K.3
Chiodi, I.4
Favero, F.5
Mello-Grand, M.6
Dei Tos, A.P.7
Giulotto, E.8
Taraboletti, G.9
D'Incalci, M.10
Mondello, C.11
-
32
-
-
84861552793
-
The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis
-
Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D., Hung, M. C, Nakayama, K. I., and Lin, H. K. (2012) The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.. Cell 149, 1098-1111
-
(2012)
Cell
, vol.149
, pp. 1098-1111
-
-
Chan, C.H.1
Li, C.F.2
Yang, W.L.3
Gao, Y.4
Lee, S.W.5
Feng, Z.6
Huang, H.Y.7
Tsai, K.K.8
Flores, L.G.9
Shao, Y.10
Hazle, J.D.11
Yu, D.12
Wei, W.13
Sarbassov, D.14
Hung, M.C.15
Nakayama, K.I.16
Lin, H.K.17
-
33
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart, C. M. (2001) Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70, 503-533
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
34
-
-
2342477917
-
The novel functions of ubiquitination in signaling
-
Sun, L., and Chen, Z. J. (2004) The novel functions of ubiquitination in signaling. Curr. Opin Cell Biol. 16, 119-126
-
(2004)
Curr. Opin Cell Biol.
, vol.16
, pp. 119-126
-
-
Sun, L.1
Chen, Z.J.2
-
35
-
-
23144449208
-
Ubiquitin and ubiquitin-like proteins as multifunctional signals
-
Welchman, R. L., Gordon, C, and Mayer, R. J. (2005) Ubiquitin and ubiquitin-like proteins as multifunctional signals. Nat. Rev. Mol. Cell Biol. 6, 599-609
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 599-609
-
-
Welchman, R.L.1
Gordon, C.2
Mayer, R.J.3
-
36
-
-
33847705665
-
Role of ubiquitin- and Ubl-binding proteins in cell signaling
-
Kirkin, V., and Dikic, I. (2007) Role of ubiquitin- and Ubl-binding proteins in cell signaling. Curr. Opin. Cell Biol. 19, 199-205
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 199-205
-
-
Kirkin, V.1
Dikic, I.2
-
37
-
-
18744379729
-
CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion
-
Doye, A., Mettouchi, A., Bossis, G., Clément, R., Buisson-Touati, C, Flatau, G., Gagnoux, L., Piechaczyk, M., Boquet, P., and Lemichez, E. (2002) CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion.. Cell 111, 553-564
-
(2002)
Cell
, vol.111
, pp. 553-564
-
-
Doye, A.1
Mettouchi, A.2
Bossis, G.3
Clément, R.4
Buisson-Touati, C.5
Flatau, G.6
Gagnoux, L.7
Piechaczyk, M.8
Boquet, P.9
Lemichez, E.10
-
38
-
-
6344231828
-
The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1
-
Lanning, C. C, Daddona, J. L., Ruiz-Velasco, R., Shafer, S. H, and Williams, C. L. (2004) The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1. J. Biol. Chem. 279, 44197-44210
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44197-44210
-
-
Lanning, C.C.1
Daddona, J.L.2
Ruiz-Velasco, R.3
Shafer, S.H.4
Williams, C.L.5
-
39
-
-
33744755685
-
-/- cells
-
-/- cells.. Mol. Biol. Cell 17, 2489-2497
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2489-2497
-
-
Boyer, L.1
Turchi, L.2
Desnues, B.3
Doye, A.4
Ponzio, G.5
Mege, J.L.6
Yamashita, M.7
Zhang, Y.E.8
Bertoglio, J.9
Flatau, G.10
Boquet, P.11
Lemichez, E.12
-
40
-
-
78649729521
-
The role of ubiquitylation and degradation in RhoGTPase signalling. J
-
Nethe, M., and Hordijk, P. L. (2010) The role of ubiquitylation and degradation in RhoGTPase signalling. J. CellSci. 123, 4011-4018
-
(2010)
CellSci.
, vol.123
, pp. 4011-4018
-
-
Nethe, M.1
Hordijk, P.L.2
-
41
-
-
0033214995
-
Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27 (Kip1) and p21 (Cip1)
-
Perez-Roger, I., Kim, S. H, Griffiths, B., Sewing, A., and Land, H. (1999) Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27 (Kip1) and p21 (Cip1). EMBO J. 18, 5310-5320
-
(1999)
EMBO J.
, vol.18
, pp. 5310-5320
-
-
Perez-Roger, I.1
Kim, S.H.2
Griffiths, B.3
Sewing, A.4
Land, H.5
-
42
-
-
20244376911
-
BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells
-
Andreu, E. J., Lledó, E., Poch, E., Ivorra, C, Albero, M. P., Martínez-Climent, J. A., Montiel-Duarte, C, Rifón, J., Pérez-Calvo, J., Arbona, C, Prósper, F., and Pérez-Roger, I. (2005) BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells.. Cancer Res. 65, 3264-3272
-
(2005)
Cancer Res.
, vol.65
, pp. 3264-3272
-
-
Andreu, E.J.1
Lledó, E.2
Poch, E.3
Ivorra, C.4
Albero, M.P.5
Martínez-Climent, J.A.6
Montiel-Duarte, C.7
Rifón, J.8
Pérez-Calvo, J.9
Arbona, C.10
Prósper, F.11
Pérez-Roger, I.12
-
43
-
-
77953232989
-
Bortezomib decreases Rb phosphorylation and induces caspase-dependent apoptosis in Imatinib-sensitive and -resistant Bcr-Abl1-expressing cells
-
Albero, M. P., Vaquer, J. M., Andreu, E. J., Villanueva, J. J., Franch, L., Ivorra, C, Poch, E., Agirre, X., Prosper, F., and Pérez-Roger, I. (2010) Bortezomib decreases Rb phosphorylation and induces caspase-dependent apoptosis in Imatinib-sensitive and -resistant Bcr-Abl1-expressing cells.. Oncogene 29, 3276-3286
-
(2010)
Oncogene
, vol.29
, pp. 3276-3286
-
-
Albero, M.P.1
Vaquer, J.M.2
Andreu, E.J.3
Villanueva, J.J.4
Franch, L.5
Ivorra, C.6
Poch, E.7
Agirre, X.8
Prosper, F.9
Pérez-Roger, I.10
-
44
-
-
2342500360
-
The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
-
Lu, L., Schulz, H, and Wolf, D. A. (2002) The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.. BMC Cell Biol. 3, 22
-
(2002)
BMC Cell Biol.
, vol.3
, pp. 22
-
-
Lu, L.1
Schulz, H.2
Wolf, D.A.3
-
45
-
-
0030867904
-
Interleukin 3-dependent survival by the Akt protein kinase
-
Songyang, Z., Baltimore, D., Cantley, L. C, Kaplan, D. R., and Franke, T. F. (1997) Interleukin 3-dependent survival by the Akt protein kinase. Proc. Natl. Acad. Sci. U. S. A. 94, 11345-11350
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 11345-11350
-
-
Songyang, Z.1
Baltimore, D.2
Cantley, L.C.3
Kaplan, D.R.4
Franke, T.F.5
-
46
-
-
32144456975
-
Degradation of RhoA by Smurf1 ubiquitin ligase
-
Wang, H. R., Ogunjimi, A. A., Zhang, Y., Ozdamar, B., Bose, R., and Wrana, J. L. (2006) Degradation of RhoA by Smurf1 ubiquitin ligase. Methods Enzymol. 406, 437-447
-
(2006)
Methods Enzymol.
, vol.406
, pp. 437-447
-
-
Wang, H.R.1
Ogunjimi, A.A.2
Zhang, Y.3
Ozdamar, B.4
Bose, R.5
Wrana, J.L.6
-
47
-
-
77954152739
-
Ubiquitylation and proteasomal degradation of the p21 (Cip1), p27 (Kip1) and p57 (Kip2) CDK inhibitors
-
Lu, Z., and Hunter, T. (2010) Ubiquitylation and proteasomal degradation of the p21 (Cip1), p27 (Kip1) and p57 (Kip2) CDK inhibitors.. Cell Cycle 9, 2342-2352
-
(2010)
Cell Cycle
, vol.9
, pp. 2342-2352
-
-
Lu, Z.1
Hunter, T.2
-
48
-
-
44349122993
-
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP. Tipping the scales of cancer
-
Frescas, D., and Pagano, M. (2008) Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP. Tipping the scales of cancer. Nat. Rev. Cancer 8, 438-449
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 438-449
-
-
Frescas, D.1
Pagano, M.2
-
49
-
-
84866130598
-
The GTPase-deficient Rnd proteins are stabilized by their effectors. J
-
Goh, L. L., and Manser, E. (2012) The GTPase-deficient Rnd proteins are stabilized by their effectors. J. Biol. Chem. 287, 31311-31320
-
(2012)
Biol. Chem.
, vol.287
, pp. 31311-31320
-
-
Goh, L.L.1
Manser, E.2
-
50
-
-
0344758986
-
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
-
Wang, H. R., Zhang, Y., Ozdamar, B., Ogunjimi, A. A., Alexandrova, E., Thomsen, G. H., and Wrana, J. L. (2003) Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302, 1775-1779
-
(2003)
Science
, vol.302
, pp. 1775-1779
-
-
Wang, H.R.1
Zhang, Y.2
Ozdamar, B.3
Ogunjimi, A.A.4
Alexandrova, E.5
Thomsen, G.H.6
Wrana, J.L.7
-
51
-
-
70349168448
-
Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement
-
Chen, Y., Yang, Z., Meng, M., Zhao, Y., Dong, N., Yan, H., Liu, L., Ding, M., Peng, H. B., and Shao, F. (2009) Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement.. Mol. Cell 35, 841-855
-
(2009)
Mol. Cell
, vol.35
, pp. 841-855
-
-
Chen, Y.1
Yang, Z.2
Meng, M.3
Zhao, Y.4
Dong, N.5
Yan, H.6
Liu, L.7
Ding, M.8
Peng, H.B.9
Shao, F.10
-
52
-
-
37849050182
-
Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process
-
Visvikis, O., Lorès, P., Boyer, L., Chardin, P., Lemichez, E., and Gacon, G. (2008) Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process.. FEBS J. 275, 386-396
-
(2008)
FEBS J.
, vol.275
, pp. 386-396
-
-
Visvikis, O.1
Lorès, P.2
Boyer, L.3
Chardin, P.4
Lemichez, E.5
Gacon, G.6
-
53
-
-
17144377069
-
RhoE function is regulated by ROCK I-mediated phosphorylation
-
Riento, K., Totty, N., Villalonga, P., Garg, R., Guasch, R., and Ridley, A. J. (2005) RhoE function is regulated by ROCK I-mediated phosphorylation. EMBOJ. 24, 1170-1180
-
(2005)
EMBOJ.
, vol.24
, pp. 1170-1180
-
-
Riento, K.1
Totty, N.2
Villalonga, P.3
Garg, R.4
Guasch, R.5
Ridley, A.J.6
-
54
-
-
84876937357
-
14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins
-
Riou, P., Kjaer, S., Garg, R., Purkiss, A., George, R., Cain, R. J., Bineva, G., Reymond, N., McColl, B., Thompson, A. J., O'Reilly, N., McDonald, N. Q., Parker, P. J., and Ridley, A. J. (2013) 14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins. Cell 153, 640-653
-
(2013)
Cell
, vol.153
, pp. 640-653
-
-
Riou, P.1
Kjaer, S.2
Garg, R.3
Purkiss, A.4
George, R.5
Cain, R.J.6
Bineva, G.7
Reymond, N.8
McColl, B.9
Thompson, A.J.10
O'Reilly, N.11
McDonald, N.Q.12
Parker, P.J.13
Ridley, A.J.14
-
55
-
-
70350695998
-
Regulation of Rnd3 localization and function by protein kinase Ca-mediated phosphorylation
-
Madigan, J. P., Bodemann, B. O., Brady, D. C, Dewar, B. J., Keller, P. J., Leitges, M., Philips, M. R., Ridley, A. J., Der, C. J., and Cox, A. D. (2009) Regulation of Rnd3 localization and function by protein kinase Ca-mediated phosphorylation. Biochem. J. 424, 153-161
-
(2009)
Biochem. J.
, vol.424
, pp. 153-161
-
-
Madigan, J.P.1
Bodemann, B.O.2
Brady, D.C.3
Dewar, B.J.4
Keller, P.J.5
Leitges, M.6
Philips, M.R.7
Ridley, A.J.8
Der, C.J.9
Cox, A.D.10
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