Nutritional potential of metabolic remodelling of white adipose tissue

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 16, Issue 6, 2013, Pages 650-656

  Palou, Andreu ^a   Picó, Catalina ^a   Luisa Bonet, Maria ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

Author keywords

early life nutrition; metabolic programming; obesity; white adipose tissue browning

Indexed keywords

LEPTIN;

ADIPOCYTE; ADIPOGENESIS; BODY FAT; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; DIETARY INTAKE; ENERGY METABOLISM; EXERCISE; HUMAN; NONHUMAN; OBESITY; PERINATAL PERIOD; REVIEW; SYMPATHETIC INNERVATION; THERMOGENESIS; WHITE ADIPOSE TISSUE;

ANIMALIA; RATTUS; RODENTIA;

ADIPOGENESIS; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ADIPOSITY; ANIMALS; DIET; ENERGY METABOLISM; HUMANS; LEPTIN; LIFE STYLE; NUTRITIONAL STATUS; OBESITY; STEM CELLS;

EID: 84886445603     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e328365980f     Document Type: Review

References (57)

1. Pico C, PalouM, Priego T, et al.Metabolic programming of obesity by energy restriction during the perinatal period: different outcomes depending on gender and period, type and severity of restriction. Front Physiol 2012; 3:436.
2. Spencer SJ. Early life programming of obesity: the impact of the perinatal environment on the development of obesity and metabolic dysfunction in the offspring. Curr Diabetes Rev 2012; 8:55-68.
3. Breton C. The hypothalamus-adipose axis is a key target of developmental programming by maternal nutritional manipulation. J Endocrinol 2013; 216:R19-31.
4. Zhang T, Guan H, Arany E, et al. Maternal protein restriction permanently programs adipocyte growth and development in adult male rat offspring. J Cell Biochem 2007; 101:381-388.
5. Guan H, Arany E, van Beek JP, et al. Adipose tissue gene expression profiling reveals distinct molecular pathways that define visceral adiposity in offspring of maternal protein-restricted rats. Am J Physiol Endocrinol Metab 2005; 288:E663-E673.
6. Garcia AP, Palou M, Sanchez J, et al. Moderate caloric restriction during gestation in rats alters adipose tissue sympathetic innervation and later adiposity in offspring. PLoS One 2011; 6:e17313.
7. Xue B, Rim JS, Hogan JC, et al. Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat. J Lipid Res 2007; 48:41-51.
8. Ailhaud G, Hauner H. Development of white adipose tissue. Bray GA, Bouchard C, editors. , 2nd edition New York: Marcel Decker, Inc; 2004.
9. Oliver P, Pico C, Palou A. Differential expression of genes for uncoupling proteins 1, 2 and 3 in brown and white adipose tissue depots during rat development. Cell Mol Life Sci 2001; 58:470-476.
10. Delahaye F, Lukaszewski MA, Wattez JS, et al. Maternal perinatal undernutrition programs a 'brown-like' phenotype of gonadal white fat in male rat at weaning. Am J Physiol Regul Integr Comp Physiol 2010; 299:R101-R110.
11. Bonet ML, Oliver P, Palou A. Pharmacological and nutritional agents promoting browning of white adipose tissue. Biochim Biophys Acta 2013; 1831:969-985.
12. Palou M, Priego T, Sanchez J, et al. Moderate caloric restriction in lactating rats protects offspring against obesity and insulin resistance in later life. Endocrinology 2010; 151:1030-1041.
13. Palou M, Torrens JM, Priego T, et al. Moderate caloric restriction in lactating rats programs their offspring for a better response to HF diet feeding in a sexdependent manner. J Nutr Biochem 2011; 22:574-584.
14. Kozak LP, Koza RA, Anunciado-Koza R, et al. Inherent plasticity of brown adipogenesis in white fat of mice allows for recovery from effects of postnatal malnutrition. PLoS One 2012; 7:e30392.
15. Palou M, Priego T, Sanchez J, et al. Moderate caloric restriction in lactating rats protects offspring against obesity and insulin resistance in later life. Endocrinology 2010; 151:1030-1041.
16. Palou M, Torrens JM, Priego T, et al. Moderate caloric restriction in lactating rats programs their offspring for a better response to HF diet feeding in a sexdependent manner. J Nutr Biochem 2011; 22:574-584.
17. Kozak LP, Koza RA, Anunciado-Koza R, et al. Inherent plasticity of brown adipogenesis in white fat of mice allows for recovery from effects of postnatal malnutrition. PLoS One 2012; 7:e30392.
18. Symonds ME. Brown adipose tissue growth and development. Scientifica 2013; http://dx.doi.org/10.1155/2013/305763 [Epub ahead of print]. doi: 10.1155/2013/305763.
19. Priego T, Sanchez J, Palou A, Pico C. Effect of high-fat diet feeding on leptin receptor expression in white adipose tissue in rats: depot- and sex-related differential response. Genes Nutr 2009; 4:151-156.
20. Desai M, Gayle D, Babu J, Ross MG. The timing of nutrient restriction during rat pregnancy/lactation alters metabolic syndrome phenotype. Am J Obstet Gynecol 2007; 196:555; e551-557.
21. Breton C, Lukaszewski MA, Risold PY, et al. Maternal prenatal undernutrition alters the response of POMC neurons to energy status variation in adult male rat offspring. Am J Physiol Endocrinol Metab 2009; 296: E462-E472.
22. Garcia AP, Palou M, Priego T, et al. Moderate caloric restriction during gestation results in lower arcuate nucleus NPY- and aMSH-neurons and impairs hypothalamic response to fed/fasting conditions in weaned rats. Diabetes, obesity and metabolism 2010; 12:403-413.
23. Palou M, Konieczna J, Torrens JM, et al. Impaired insulin and leptin sensitivity in the offspring of moderate caloric-restricted dams during gestation is early programmed. J Nutr Biochem 2012; 23:1627-1639.
24. Palou A, Pico C. Leptin intake during lactation prevents obesity and affects food intake and food preferences in later life. Appetite 2009; 52:249-252.
25. Bouret SG, Simerly RB. Minireview: leptin and development of hypothalamic feeding circuits. Endocrinology 2004; 145:2621-2626.
26. Pico C, Jilkova ZM, Kus V, et al. Perinatal programming of body weight control by leptin: putative roles of AMP kinase and muscle thermogenesis. Am J Clin Nutr 2011; 94:1830S-1837S.
27. Yura S, Itoh H, Sagawa N, et al. Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metab 2005; 1:371-378.
28. Pico C, Oliver P, Sanchez J, et al. The intake of physiological doses of leptin during lactation in rats prevents obesity in later life. Int J Obes (Lond) 2007; 31:1199-1209.
29. Sanchez J, Priego T, Palou M, et al. Oral supplementation with physiological doses of leptin during lactation in rats improves insulin sensitivity and affects food preferences later in life. Endocrinology 2008; 149:733-740.
30. Priego T, Sanchez J, Palou A, Pico C. Leptin intake during the suckling period improves the metabolic response of adipose tissue to a high-fat diet. Int J Obes (Lond) 2010; 34:809-819.
31. Jones R. Obesity: leptin intake during the suckling period may protect against obesity and metabolic-related disorders. Nat Rev Gastroenterol Hepatol 2010; 7:359.
32. Boss O, Farmer SR. Recruitment of brown adipose tissue as a therapy for obesity-associated diseases. Front Endocrinol (Lausanne) 2012; 3:14.
33. Petrovic N, Walden TB, Shabalina IG, et al. Chronic peroxisome proliferatoractivated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem 2010; 285:7153-7164.
34. Wu J, Bostrom P, Sparks LM, et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 2012; 150:366-376.
35. Schulz TJ, Huang P, Huang TL, et al. Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature 2013; 495:379-383.
36. Ricquier D, Nechad M, Mory G. Ultrastructural and biochemical characterization of human brown adipose tissue in pheochromocytoma. J Clin Endocrinol Metab 1982; 54:803-807.
37. Lee P, Werner CD, Kebebew E, Celi FS. Functional thermogenic beige adipogenesis is inducible in human neck fat. Int J Obes (Lond) 2013. [Epub ahead of print]. doi: 10.1038/ijo.2013.82.
38. Flachs P, Rossmeisl M, Kuda O, Kopecky J. Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: a key to lean phenotype. Biochim Biophys Acta 2013; 1831:986-1003.
39. Kusminski CM, Scherer PE. Mitochondrial dysfunction in white adipose tissue. Trends Endocrinol Metab 2012; 23:435-443.
40. Flachs P, Ruhl R, Hensler M, et al. Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids. Diabetologia 2011; 54:2626-2638.
41. Vogler O, Lopez-Bellan A, Alemany R, et al. Structure-effect relation of C18 long-chain fatty acids in the reduction of body weight in rats. Int J Obes (Lond) 2008; 32:464-473.
42. Wendel AA, Purushotham A, Liu LF, Belury MA. Conjugated linoleic acid induces uncoupling protein 1 in white adipose tissue of ob/ob mice. Lipids 2009; 44:975-982.
43. Liu YC, Satoh K, Hasegawa Y. Feeding scallop shell powder induces the expression of uncoupling protein 1 (UCP1) in white adipose tissue of rats. Biosci Biotechnol Biochem 2006; 70:2733-2738.
44. Akagiri S, Naito Y, Ichikawa H, et al. Bofutsushosan, an oriental herbal medicine, attenuates the weight gain of white adipose tissue and the increased size of adipocytes associated with the increase in their expression of uncoupling protein 1 in high-fat diet-fed male KK/Ta mice. J Clin Biochem Nutr 2008; 42:158-166.
45. Maeda H, Hosokawa M, Sashima T, et al. Fucoxanthin from edible seaweed, undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Biochem Biophys Res Commun 2005; 332:392-397.
46. Yoneshiro T, Aita S, Kawai Y, et al. Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans. Am J Clin Nutr 2012; 95:845-850.
47. Timmers S, Konings E, Bilet L, et al. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 2011; 14:612-622.
48. Gaullier JM, Halse J, Hoye K, et al. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am J Clin Nutr 2004; 79:1118-1125.
49. Buckley JD, Howe PR. Long-chain omega-3 polyunsaturated fatty acids may be beneficial for reducing obesity-a review. Nutrients 2010; 2:1212-1230.
50. De Matteis R, Lucertini F, Guescini M, et al. Exercise as a new physiological stimulus for brown adipose tissue activity. Nutr Metab Cardiovasc Dis 2013; 23:582-590.
51. Ringholm S, Grunnet Knudsen J, Leick L, et al. PGC-1alpha is required for exercise- and exercise training-induced UCP1 up-regulation in mouse white adipose tissue. PLoS One 2013; 8:e64123.
52. Bostrom P, Wu J, Jedrychowski MP, et al. A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012; 481:463-468.
53. Elbelt U, Hofmann T, Stengel A. Irisin: what promise does it hold? Curr Opin Clin Nutr Metab Care 2013; 16:541-547.
54. Fisher FM, Kleiner S, Douris N, et al. FGF21 regulates PGC-1alpha and browning of white adipose tissues in adaptive thermogenesis. Genes Dev 2012; 26:271-281.
55. Kim KH, Jeong YT, Oh H, et al. Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med 2013; 19:83-92.
56. Cuevas-Ramos D, Almeda-Valdes P, Meza-Arana CE, et al. Exercise increases serum fibroblast growth factor 21 (FGF21) levels. PLoS One 2012; 7:e38022.
57. Kim KH, Kim SH, Min YK, et al. Acute exercise induces FGF21 expression in mice and in healthy humans. PLoS One 2013; 8:e63517.