Bradykinin Inhibits Oxidative Stress-Induced Cardiomyocytes Senescence via Regulating Redox State

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Dong, Ruolan ^a   Xu, Xizhen ^a   Li, Geng ^a   Feng, Wenjing ^a   Zhao, Gang ^a   Zhao, Junjie ^a   Wang, Dao Wen ^a   Tu, Ling ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; BRADYKININ B2 RECEPTOR; COPPER ZINC SUPEROXIDE DISMUTASE; GLYCOPROTEIN GP 91; HYDROGEN PEROXIDE; ICATIBANT; MANGANESE SUPEROXIDE DISMUTASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROTEIN P21; PROTEIN P47; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL AGING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVITY; HEART MUSCLE CELL; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; RAT; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; BRADYKININ; CELL AGING; CELL LINE; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLOW CYTOMETRY; HYDROGEN PEROXIDE; MYOCYTES, CARDIAC; NADPH OXIDASE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; RECEPTOR, BRADYKININ B2; SUPEROXIDE DISMUTASE;

EID: 84886445547     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077034     Document Type: Article

References (39)

1. Park SK, (2011) Genomic approaches for the understanding of aging in model organisms. BMB Rep 44: 291-297.
2. Bernhard D, Laufer G, (2008) The aging cardiomyocyte: a mini-review. Gerontology 54: 24-31.
3. Gandarillas A, (2000) Epidermal differentiation, apoptosis, and senescence: common pathways? Exp Gerontol 35: 53-62.
4. Freedman DA, Folkman J, (2005) CDK2 translational down-regulation during endothelial senescence. Exp Cell Res 307: 118-130.
5. Unterluggauer H, Hampel B, Zwerschke W, Jansen-Durr P, (2003) Senescence-associated cell death of human endothelial cells: the role of oxidative stress. Exp Gerontol 38: 1149-1160.
6. Oeseburg H, Iusuf D, van der Harst P, van Gilst WH, Henning RH, et al. (2009) Bradykinin protects against oxidative stress-induced endothelial cell senescence. Hypertension 53: 417-422.
7. Minamino T, Komuro I, (2007) Vascular cell senescence: contribution to atherosclerosis. Circ Res 100: 15-26.
8. Tikellis C, Bernardi S, Burns WC, (2011) Angiotensin-converting enzyme 2 is a key modulator of the renin-angiotensin system in cardiovascular and renal disease. Curr Opin Nephrol Hypertens 20: 62-68.
9. Cyr M, Eastlund T, Blais C Jr, Rouleau JL, Adam A, (2001) Bradykinin metabolism and hypotensive transfusion reactions. Transfusion 41: 136-150.
10. Xu X, Tu L, Jiang W, Feng W, Zhao CX, et al. (2012) Bradykinin prevents the apoptosis of NIT-1 cells induced by TNF-alpha via the PI3K/Akt and MAPK signaling pathways. Int J Mol Med 29: 891-898.
11. Tu L, Xu X, Wan H, Zhou C, Deng J, et al. (2008) Delivery of recombinant adeno-associated virus-mediated human tissue kallikrein for therapy of chronic renal failure in rats. Hum Gene Ther 19: 318-330.
12. Kintsurashvili E, Duka A, Ignjacev I, Pattakos G, Gavras I, et al. (2005) Age-related changes of bradykinin B1 and B2 receptors in rat heart. Am J Physiol Heart Circ Physiol 289: H202-205.
13. Linz W, Wohlfart P, Scholkens BA, Malinski T, Wiemer G, (1999) Interactions among ACE, kinins and NO. Cardiovasc Res 43: 549-561.
14. Kakoki M, Kizer CM, Yi X, Takahashi N, Kim HS, et al. (2006) Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. J Clin Invest 116: 1302-1309.
15. Dimri GP, Lee X, Basile G, Acosta M, Scott G, et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 92: 9363-9367.
16. Iglesias-Ara A, Zenarruzabeitia O, Fernandez-Rueda J, Sánchez-Tilló E, Field SJ, et al. (2010) Accelerated DNA replication in E2F1- and E2F2-deficient macrophages leads to induction of the DNA damage response and p21(CIP1)-dependent senescence. Oncogene 29: 5579-5590.
17. Wang H, Joseph JA, (1999) Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic Biol Med 27: 612-616.
18. Feng J, Damrauer SM, Lee M, Sellke FW, Ferran C, et al. (2010) Endothelium-Dependent Coronary Vasodilatation Requires NADPH Oxidase-Derived Reactive Oxygen Species. Arterioscler Thromb Vasc Biol 30: 1703-1710.
19. Yang S, Chen C, Wang DW, (2012) Protective effects of Acyl-coA thioesterase 1 on diabetic heart via PPAR alpha/PGC1alpha signaling. PLoS One 7 (11) (): e50376.
20. Zhang M, Song P, Xu J, Zou MH, (2011) Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase. Arterioscler Thromb Vasc Biol Jan 31 (1) (): 125-32.
21. Vulliamy TJ, (2009) Premature aging. Cell Mol Life Sci 66: 3091-3094.
22. Passos JF, Saretzki G, von Zglinicki T, (2007) DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? Nucleic Acids Res 35: 7505-7513.
23. Clarke R, Shajahan AN, Riggins RB, Cho Y, Crawford A, et al. (2009) Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells. J Steroid Biochem Mol Biol 114: 8-20.
24. Rahman K, (2007) Studies on free radicals, antioxidants, and co-factors. Clin Interv Aging 2: 219-236.
25. Nystrom T, (2005) Role of oxidative carbonylation in protein quality control and senescence. EMBO J 24: 1311-1317.
26. Uttara B, Singh AV, Zamboni P, Mahajan RT, (2009) Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 7: 65-74.
27. Kanai AJ, Mesaros S, Finkel MS, Oddis CV, Birder LA, et al. (1997) Beta-adrenergic regulation of constitutive nitric oxide synthase in cardiac myocytes. Am J Physiol 273: C1371-1377.
28. Palmer RM, Ferrige AG, Moncada S, (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526.
29. Gao F, Gao E, Yue TL, Ohlstein EH, Lopez BL, et al. (2002) Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation 105: 1497-1502.
30. Yin H, Chao L, Chao J, (2008) Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion. Life Sci 82: 156-165.
31. Frank A, Bonney M, Bonney S, Weitzel L, Koeppen M, et al. (2012) Myocardial ischemia reperfusion injury: from basic science to clinical bedside. Semin Cardiothorac Vasc Anesth 16: 123-132.
32. Bokov A, Chaudhuri A, Richardson A, (2004) The role of oxidative damage and stress in aging. Mech Ageing Dev 125: 811-826.
33. Sayama K, Shirakata Y, Midorikawa K, Hanakawa Y, Hashimoto K, (1999) Possible involvement of p21 but not of p16 or p53 in keratinocyte senescence. J Cell Physiol 179: 40-44.
34. Westin ER, Aykin-Burns N, Buckingham EM, Spitz DR, Goldman FD, et al. (2011) The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency. Antioxid Redox Signal 14: 985-997.
35. Zhang X, Li J, Sejas DP, Pang Q, (2005) The ATM/p53/p21 pathway influences cell fate decision between apoptosis and senescence in reoxygenated hematopoietic progenitor cells. J Biol Chem 280: 19635-19640.
36. Zieman SJ, Gerstenblith G, Lakatta EG, Rosas GO, Vandegaer K, et al. (2001) Upregulation of the nitric oxide-cGMP pathway in aged myocardium: physiological response to l-arginine. Circ Res 88: 97-102.
37. Vasa M, Breitschopf K, Zeiher AM, Dimmeler S, (2000) Nitric oxide activates telomerase and delays endothelial cell senescence. Circ Res 87: 540-542.
38. Lou Z, Chen J, (2006) Cellular senescence and DNA repair. Exp Cell Res 312: 2641-2646.
39. Frantz S, Brandes RP, Hu K, Rammelt K, Wolf J, et al. (2006) Left ventricular remodeling after myocardial infarction in mice with targeted deletion of the NADPH oxidase subunit gp91PHOX. Basic Res Cardiol 101: 127-132.