The ATM/p53/p21 pathway influences cell fate decision between apoptosis and senescence in reoxygenated hematopoietic progenitor cells

Journal of Biological Chemistry

Volumn 280, Issue 20, 2005, Pages 19635-19640

  Zhang, Xiaoling ^a   Li, June ^a   Sejas, Daniel P ^a   Pang, Qishen ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; BONE; CYTOLOGY; DNA; ENZYME INHIBITION; KETONES; OXIDATION; TISSUE;

APOPTOSIS; HEMATOPOIETIC CELLS; OXIDATIVE STRESS; TRANSIENT HYPOXIA;

CELLS;

ATM PROTEIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BETA GALACTOSIDASE; CASPASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; PROTEIN P16INK4A; PROTEIN P21; PROTEIN P53; CDKN1A PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA BINDING PROTEIN; FANCC PROTEIN, MOUSE; FANCONI ANEMIA GROUP C PROTEIN; FANCONI ANEMIA PROTEIN; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL FATE; CELL LINEAGE; CELL MATURATION; CELL MIGRATION; COLONY FORMATION; CONTROLLED STUDY; DNA DAMAGE; HEMATOPOIETIC STEM CELL; HYPOXIA; KNOCKOUT MOUSE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REOXYGENATION; SENESCENCE; SIGNAL TRANSDUCTION; STRESS; ANIMAL; CELL AGING; CELL CYCLE; CHEMISTRY; CLONOGENIC ASSAY; CYTOLOGY; FANCONI ANEMIA; GENETICS; IN VITRO STUDY; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; APOPTOSIS; BETA-GALACTOSIDASE; CELL AGING; CELL CYCLE; CELL CYCLE PROTEINS; COLONY-FORMING UNITS ASSAY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA-BINDING PROTEINS; FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP C PROTEIN; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; HEMATOPOIETIC STEM CELLS; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 21244450353     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502262200     Document Type: Article

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