Anti-inflammatory effects of lipoic acid through inhibition of GSK-3β in lipopolysaccharide-induced BV-2 microglial cells

Neuroscience Research

Volumn 77, Issue 1-2, 2013, Pages 87-96

  Koriyama, Yoshiki ^a   Nakayama, Yuya ^a   Matsugo, Seiichi ^a   Sugitani, Kayo ^a   Ogai, Kazuhiro ^a   Takadera, Tsuneo ^b   Kato, Satoru ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b HOKURIKU UNIVERSITY   (Japan)

Author keywords

Akt; GSK 3 ; Inflammation; Lipoic acid; Microglia; NF B

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRITE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; THIOCTIC ACID; TRANSCRIPTION FACTOR RELA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE PREPARATION; UPREGULATION; WESTERN BLOTTING;

AKT; GLYCOGEN SYNTHASE KINASE-3Β; GSK-3Β; IL-1Β; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLAMMATION; INOS; INTERLEUKIN-1Β; LA; LICL; LIPOIC ACID; LIPOPOLYSACCHARIDE; LITHIUM CHLORIDE; LPS; LY; LY294002; MICROGLIA; NF-ΚB; NUCLEAR FACTOR-KAPPA B; TNFΑ; TUMOR NECROSIS FACTOR Α;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CEREBRAL CORTEX; GLYCOGEN SYNTHASE KINASE 3; LIPOPOLYSACCHARIDES; LITHIUM CHLORIDE; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; THIOCTIC ACID; TRANSCRIPTION FACTOR RELA;

EID: 84886441627     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2013.07.001     Document Type: Article

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