Using functional signature ontology (FUSION) to identify mechanisms of action for Natural products

Science Signaling

Volumn 6, Issue 297, 2013, Pages

  Potts, Malia B ^a   Kim, Hyun Seok ^a   Fisher, Kurt W ^b   Hu, Youcai ^c   Carrasco, Yazmin P ^c   Bulut, Gamze Betul ^a   Ou, Yi Hung ^a   Herrera Herrera, Mireya L ^a   Cubillos, Federico ^a   Mendiratta, Saurabh ^a   Xiao, Guanghua ^a   Hofree, Matan ^d   Ideker, Trey ^d   Xie, Yang ^a,e   Huang, Lily Jun Shen ^a   Lewis, Robert E ^b   MacMillan, John B ^c   White, Michael A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BAFILOMYCIN A1; BAFILOMYCIN B1; BAFILOMYCIN B2; BAFILOMYCIN D; DISCOIDIN; DISCOIPYRROLE A; MICRORNA; NATURAL PRODUCT; PROTEIN KINASE B; SMALL INTERFERING RNA; SNB 003 CMP1; UNCLASSIFIED DRUG;

ALPHAPROTEOBACTERIA; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BACILLUS; BACTERIAL STRAIN; BIOLOGICAL ACTIVITY; CELL DIFFERENTIATION; CELL FUNCTION; CHEMOTAXIS; COLORECTAL CARCINOMA; COMPETITIVE INHIBITION; CRYSTALLIZATION; DRUG SCREENING; ENZYME ACTIVATION; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; GENE EXPRESSION; GENE MAPPING; HUMAN; MARINE ENVIRONMENT; MEDICAL RESEARCH; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REPORTER GENE; SQUAMOUS CELL CARCINOMA; STREPTOMYCES; STRUCTURE ACTIVITY RELATION; TARGET CELL; WESTERN BLOTTING;

ANIMALS; AUTOPHAGY; BACTERIA; BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; CELLS, CULTURED; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE ONTOLOGY; GENE REGULATORY NETWORKS; HCT116 CELLS; HUMANS; INVERTEBRATES; MARINE BIOLOGY; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICRORNAS; MOLECULAR STRUCTURE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA INTERFERENCE; TRANSCRIPTOME;

EID: 84886402348     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004657     Document Type: Article

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