메뉴 건너뛰기




Volumn 587, Issue 21, 2013, Pages 3487-3494

Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages

Author keywords

ARK ct; GRK2; Inflammation; Mitochondria; Subcellular localization

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOCHONDRIAL DNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE;

EID: 84886308017     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.09.002     Document Type: Article
Times cited : (30)

References (46)
  • 1
    • 0141629679 scopus 로고    scopus 로고
    • Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. (Translated from eng)
    • (in eng)
    • P. Penela, C. Ribas, and F. Mayor Jr. Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. (Translated from eng) Cell Signal. 15 11 2003 973 981 (in eng)
    • (2003) Cell Signal. , vol.15 , Issue.11 , pp. 973-981
    • Penela, P.1    Ribas, C.2    Mayor, Jr.F.3
  • 2
    • 33947375174 scopus 로고    scopus 로고
    • Physiological roles of G protein-coupled receptor kinases and arrestins. (Translated from eng)
    • (in eng)
    • R.T. Premont, and R.R. Gainetdinov Physiological roles of G protein-coupled receptor kinases and arrestins. (Translated from eng) Annu. Rev. Physiol. 69 2007 511 534 (in eng)
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 511-534
    • Premont, R.T.1    Gainetdinov, R.R.2
  • 3
    • 33947354585 scopus 로고    scopus 로고
    • Regulation of receptor tyrosine kinase signaling by GRKs and beta-arrestins. (Translated from eng)
    • (in eng)
    • C.J. Hupfeld, and J.M. Olefsky Regulation of receptor tyrosine kinase signaling by GRKs and beta-arrestins. (Translated from eng) Annu. Rev. Physiol. 69 2007 561 577 (in eng)
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 561-577
    • Hupfeld, C.J.1    Olefsky, J.M.2
  • 4
    • 70450227198 scopus 로고    scopus 로고
    • The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance. (Translated from eng)
    • (in eng)
    • E. Cipolletta The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance. (Translated from eng) Cardiovasc. Res. 84 3 2009 407 415 (in eng)
    • (2009) Cardiovasc. Res. , vol.84 , Issue.3 , pp. 407-415
    • Cipolletta, E.1
  • 5
    • 33750218229 scopus 로고    scopus 로고
    • Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK. (Translated from eng)
    • (in eng)
    • S. Peregrin Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK. (Translated from eng) Curr. Biol. 16 20 2006 2042 2047 (in eng)
    • (2006) Curr. Biol. , vol.16 , Issue.20 , pp. 2042-2047
    • Peregrin, S.1
  • 6
    • 33947424008 scopus 로고    scopus 로고
    • The G protein-coupled receptor kinase (GRK) interactome: Role of GRKs in GPCR regulation and signaling. (Translated from eng)
    • (in eng)
    • C. Ribas The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling. (Translated from eng) Biochim. Biophys. Acta 1768 4 2007 913 922 (in eng)
    • (2007) Biochim. Biophys. Acta , vol.1768 , Issue.4 , pp. 913-922
    • Ribas, C.1
  • 7
    • 72449146904 scopus 로고    scopus 로고
    • G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha. (Translated from eng)
    • (in eng)
    • Patial S, Luo J, Porter KJ, Benovic JL, & Parameswaran N. (G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha. (Translated from eng), Biochem. J. 425 (1):169-178 (in eng).
    • Biochem. J , vol.425 , Issue.1 , pp. 169-178
    • Patial, S.1    Luo, J.2    Porter, K.J.3    Benovic, J.L.4    Parameswaran, N.5
  • 8
    • 0034111099 scopus 로고    scopus 로고
    • Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: Direct interaction of kinase N terminus with activated galphaq (Translated from eng)
    • (in eng)
    • M. Sallese, S. Mariggio, E. D'Urbano, L. Iacovelli, and A. De Blasi Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated galphaq (Translated from eng) Mol. Pharmacol. 57 4 2000 826 831 (in eng)
    • (2000) Mol. Pharmacol. , vol.57 , Issue.4 , pp. 826-831
    • Sallese, M.1    Mariggio, S.2    D'Urbano, E.3    Iacovelli, L.4    De Blasi, A.5
  • 9
    • 33947585981 scopus 로고    scopus 로고
    • Phosphorylation-independent attenuation of GPCR signalling. (Translated from eng)
    • (in eng)
    • S.S. Ferguson Phosphorylation-independent attenuation of GPCR signalling. (Translated from eng) Trends Pharmacol. Sci. 28 4 2007 173 179 (in eng)
    • (2007) Trends Pharmacol. Sci. , vol.28 , Issue.4 , pp. 173-179
    • Ferguson, S.S.1
  • 10
    • 84856427725 scopus 로고    scopus 로고
    • GRK2 at the control shaft of cellular metabolism. (Translated from eng)
    • M. Ciccarelli, E. Cipolletta, and G. Iaccarino GRK2 at the control shaft of cellular metabolism. (Translated from eng) Curr. Pharm. Des. 18 2 2012 121 127
    • (2012) Curr. Pharm. Des. , vol.18 , Issue.2 , pp. 121-127
    • Ciccarelli, M.1    Cipolletta, E.2    Iaccarino, G.3
  • 11
    • 79955782045 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia. (Translated from eng)
    • (in eng)
    • M. Ciccarelli G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia. (Translated from eng) Circulation 123 18 2012 1953 1962 (in eng)
    • (2012) Circulation , vol.123 , Issue.18 , pp. 1953-1962
    • Ciccarelli, M.1
  • 12
    • 77952840083 scopus 로고    scopus 로고
    • The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets. (Translated from eng)
    • P. Penela, C. Murga, C. Ribas, V. Lafarga, and F. Mayor Jr. The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets. (Translated from eng) Br. J. Pharmacol. 160 4 2010 821 832
    • (2010) Br. J. Pharmacol. , vol.160 , Issue.4 , pp. 821-832
    • Penela, P.1    Murga, C.2    Ribas, C.3    Lafarga, V.4    Mayor, Jr.F.5
  • 13
    • 67049101075 scopus 로고    scopus 로고
    • New roles of G protein-coupled receptor kinase 2 (GRK2) in cell migration
    • P. Penela, C. Ribas, I. Aymerich, and F. Mayor Jr. New roles of G protein-coupled receptor kinase 2 (GRK2) in cell migration Cell Adh. Migr. 3 1 2009 19 23
    • (2009) Cell Adh. Migr. , vol.3 , Issue.1 , pp. 19-23
    • Penela, P.1    Ribas, C.2    Aymerich, I.3    Mayor, Jr.F.4
  • 14
    • 33845412884 scopus 로고    scopus 로고
    • GRKs and arrestins: Regulators of migration and inflammation. (Translated from eng)
    • (in eng)
    • A. Vroon, C.J. Heijnen, and A. Kavelaars GRKs and arrestins: regulators of migration and inflammation. (Translated from eng) J. Leukoc. Biol. 80 6 2006 1214 1221 (in eng)
    • (2006) J. Leukoc. Biol. , vol.80 , Issue.6 , pp. 1214-1221
    • Vroon, A.1    Heijnen, C.J.2    Kavelaars, A.3
  • 15
    • 78650656888 scopus 로고    scopus 로고
    • Myeloid-specific GPCR kinase-2 negatively regulates NF-kappaB1p105-ERK pathway and limits endotoxemic shock in mice. (Translated from eng)
    • (in eng)
    • S. Patial Myeloid-specific GPCR kinase-2 negatively regulates NF-kappaB1p105-ERK pathway and limits endotoxemic shock in mice. (Translated from eng) J. Cell. Physiol. 226 3 2011 627 637 (in eng)
    • (2011) J. Cell. Physiol. , vol.226 , Issue.3 , pp. 627-637
    • Patial, S.1
  • 16
    • 33751167423 scopus 로고    scopus 로고
    • Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation. (Translated from eng)
    • (in eng)
    • S.M. Arraes Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation. (Translated from eng) Blood 108 9 2006 2906 2913 (in eng)
    • (2006) Blood , vol.108 , Issue.9 , pp. 2906-2913
    • Arraes, S.M.1
  • 17
    • 4444352439 scopus 로고    scopus 로고
    • Post-receptorial mechanisms underlie functional disregulation of beta2-adrenergic receptors in lymphocytes from multiple sclerosis patients. (Translated from eng)
    • (in eng)
    • M. Giorelli, P. Livrea, and M. Trojano Post-receptorial mechanisms underlie functional disregulation of beta2-adrenergic receptors in lymphocytes from multiple sclerosis patients. (Translated from eng) J. Neuroimmunol. 155 1-2 2004 143 149 (in eng)
    • (2004) J. Neuroimmunol. , vol.155 , Issue.12 , pp. 143-149
    • Giorelli, M.1    Livrea, P.2    Trojano, M.3
  • 18
    • 0035253491 scopus 로고    scopus 로고
    • Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system. (Translated from eng)
    • (in eng)
    • M.S. Lombardi Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system. (Translated from eng) J. Immunol. 166 3 2001 1635 1640 (in eng)
    • (2001) J. Immunol. , vol.166 , Issue.3 , pp. 1635-1640
    • Lombardi, M.S.1
  • 19
    • 0032919035 scopus 로고    scopus 로고
    • Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis. (Translated from eng)
    • (in eng)
    • M.S. Lombardi Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis. (Translated from eng) FASEB J. 13 6 1999 715 725 (in eng)
    • (1999) FASEB J. , vol.13 , Issue.6 , pp. 715-725
    • Lombardi, M.S.1
  • 20
    • 15444372618 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. (Translated from eng)
    • (in eng)
    • A. Vroon G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. (Translated from eng) J. Immunol. 174 7 2005 4400 4406 (in eng)
    • (2005) J. Immunol. , vol.174 , Issue.7 , pp. 4400-4406
    • Vroon, A.1
  • 21
    • 0037377235 scopus 로고    scopus 로고
    • Changes in the G-protein-coupled receptor desensitization machinery during relapsing-progressive experimental allergic encephalomyelitis. (Translated from eng)
    • (in eng)
    • A. Vroon, M.S. Lombardi, A. Kavelaars, and C.J. Heijnen Changes in the G-protein-coupled receptor desensitization machinery during relapsing- progressive experimental allergic encephalomyelitis. (Translated from eng) J. Neuroimmunol. 137 1-2 2003 79 86 (in eng)
    • (2003) J. Neuroimmunol. , vol.137 , Issue.12 , pp. 79-86
    • Vroon, A.1    Lombardi, M.S.2    Kavelaars, A.3    Heijnen, C.J.4
  • 22
    • 34548176581 scopus 로고    scopus 로고
    • Mitochondrial function in sepsis: Acute phase versus multiple organ failure. (Translated from eng)
    • (in eng)
    • M. Singer Mitochondrial function in sepsis: acute phase versus multiple organ failure. (Translated from eng) Crit. Care Med. 35 9 Suppl 2007 S441 448 (in eng)
    • (2007) Crit. Care Med. , vol.35 , Issue.9 SUPPL. , pp. 441-448
    • Singer, M.1
  • 23
    • 35349015667 scopus 로고    scopus 로고
    • Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis. (Translated from eng)
    • (in eng)
    • D.W. Haden Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis. (Translated from eng) Am. J. Respir. Crit. Care Med. 176 8 2007 768 777 (in eng)
    • (2007) Am. J. Respir. Crit. Care Med. , vol.176 , Issue.8 , pp. 768-777
    • Haden, D.W.1
  • 24
    • 84857388966 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. (Translated from eng)
    • (in eng)
    • C.A. Piantadosi, and H.B. Suliman Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. (Translated from eng) Biochim. Biophys. Acta 1820 4 2012 532 541 (in eng)
    • (2012) Biochim. Biophys. Acta , vol.1820 , Issue.4 , pp. 532-541
    • Piantadosi, C.A.1    Suliman, H.B.2
  • 25
    • 83555174502 scopus 로고    scopus 로고
    • Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis. (Translated from eng)
    • (in eng)
    • A. Fusco Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis. (Translated from eng) Cell Signal 24 2 2012 468 475 (in eng)
    • (2012) Cell Signal , vol.24 , Issue.2 , pp. 468-475
    • Fusco, A.1
  • 26
    • 56649094511 scopus 로고    scopus 로고
    • The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha. (Translated from eng)
    • (in eng)
    • D. Sorriento The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha. (Translated from eng) Proc. Natl. Acad. Sci. USA 105 46 2008 17818 17823 (in eng)
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.46 , pp. 17818-17823
    • Sorriento, D.1
  • 27
    • 13444291851 scopus 로고    scopus 로고
    • Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. (Translated from eng)
    • (in eng)
    • J. Kim Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. (Translated from eng) Proc Natl Acad Sci U S A 102 5 2005 1442 1447 (in eng)
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.5 , pp. 1442-1447
    • Kim, J.1
  • 28
    • 2642574211 scopus 로고    scopus 로고
    • AKT participates in endothelial dysfunction in hypertension. (Translated from eng)
    • (in eng)
    • G. Iaccarino AKT participates in endothelial dysfunction in hypertension. (Translated from eng) Circulation 109 21 2004 2587 2593 (in eng)
    • (2004) Circulation , vol.109 , Issue.21 , pp. 2587-2593
    • Iaccarino, G.1
  • 29
    • 78651417065 scopus 로고    scopus 로고
    • Impaired neoangiogenesis in beta(2)-adrenoceptor gene-deficient mice: Restoration by intravascular human beta(2)-adrenoceptor gene transfer and role of NFkappaB and CREB transcription factors. (Translated from eng)
    • (in eng)
    • A. Ciccarelli Impaired neoangiogenesis in beta(2)-adrenoceptor gene-deficient mice: restoration by intravascular human beta(2)-adrenoceptor gene transfer and role of NFkappaB and CREB transcription factors. (Translated from eng) Br. J. Pharmacol. 162 3 2011 712 721 (in eng)
    • (2011) Br. J. Pharmacol. , vol.162 , Issue.3 , pp. 712-721
    • Ciccarelli, A.1
  • 30
    • 70449413985 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 protects from vascular stenosis and accelerates re-endothelialization in a rat model of carotid artery injury. (Translated from eng)
    • (in eng)
    • A. Cittadini Insulin-like growth factor-1 protects from vascular stenosis and accelerates re-endothelialization in a rat model of carotid artery injury. (Translated from eng) J. Thromb. Haemostat. 7 11 2009 1920 1928 (in eng)
    • (2009) J. Thromb. Haemostat. , vol.7 , Issue.11 , pp. 1920-1928
    • Cittadini, A.1
  • 31
    • 33845385712 scopus 로고    scopus 로고
    • Beta2-adrenergic receptor polymorphisms and treatment-induced regression of left ventricular hypertrophy in hypertension. (Translated from eng)
    • (in eng)
    • G. Iaccarino Beta2-adrenergic receptor polymorphisms and treatment-induced regression of left ventricular hypertrophy in hypertension. (Translated from eng) Clin. Pharmacol. Ther. 80 6 2006 633 645 (in eng)
    • (2006) Clin. Pharmacol. Ther. , vol.80 , Issue.6 , pp. 633-645
    • Iaccarino, G.1
  • 32
    • 33644693118 scopus 로고    scopus 로고
    • Ischemic neoangiogenesis enhanced by beta2-adrenergic receptor overexpression: A novel role for the endothelial adrenergic system. (Translated from eng)
    • (in eng)
    • G. Iaccarino Ischemic neoangiogenesis enhanced by beta2-adrenergic receptor overexpression: a novel role for the endothelial adrenergic system. (Translated from eng) Circ. Res. 97 11 2005 1182 1189 (in eng)
    • (2005) Circ. Res. , vol.97 , Issue.11 , pp. 1182-1189
    • Iaccarino, G.1
  • 33
    • 71049134493 scopus 로고    scopus 로고
    • A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFkappaB activity
    • D. Sorriento A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFkappaB activity Mol. Cancer 8 2009 97
    • (2009) Mol. Cancer , vol.8 , pp. 97
    • Sorriento, D.1
  • 34
    • 79251571503 scopus 로고    scopus 로고
    • G-protein coupled receptor kinase 5 mediates lipopolysaccharide-induced NFkappaB activation in primary macrophages and modulates inflammation in vivo in mice. (Translated from eng)
    • (in eng)
    • Patial S, et al. (G-protein coupled receptor kinase 5 mediates lipopolysaccharide-induced NFkappaB activation in primary macrophages and modulates inflammation in vivo in mice. (Translated from eng), J Cell Physiol 226(5):1323-1333 (in eng).
    • J Cell Physiol , vol.226 , Issue.5 , pp. 1323-1333
    • Patial, S.1
  • 35
    • 0030615225 scopus 로고    scopus 로고
    • Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases. (Translated from eng)
    • (in eng)
    • Y. Daaka Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases. (Translated from eng) Proc. Natl. Acad. Sci. USA 94 6 1997 2180 2185 (in eng)
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , Issue.6 , pp. 2180-2185
    • Daaka, Y.1
  • 36
    • 29144497998 scopus 로고    scopus 로고
    • Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. (Translated from eng)
    • (in eng)
    • P. Penela Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. (Translated from eng) Cardiovasc. Res. 69 1 2006 46 56 (in eng)
    • (2006) Cardiovasc. Res. , vol.69 , Issue.1 , pp. 46-56
    • Penela, P.1
  • 37
    • 84859747948 scopus 로고    scopus 로고
    • Involvement of nuclear factor kappaB (NF-kappaB) signaling pathway in regulation of cardiac G protein-coupled receptor kinase 5 (GRK5) expression. (Translated from eng)
    • (in eng)
    • K.N. Islam, and W.J. Koch Involvement of nuclear factor kappaB (NF-kappaB) signaling pathway in regulation of cardiac G protein-coupled receptor kinase 5 (GRK5) expression. (Translated from eng) J. Biol. Chem. 287 16 2012 12771 12778 (in eng)
    • (2012) J. Biol. Chem. , vol.287 , Issue.16 , pp. 12771-12778
    • Islam, K.N.1    Koch, W.J.2
  • 38
  • 39
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G protein-coupled receptor regulation. (Translated from eng)
    • (in eng)
    • J.G. Krupnick, and J.L. Benovic The role of receptor kinases and arrestins in G protein-coupled receptor regulation. (Translated from eng) Annu. Rev. Pharmacol. Toxicol. 38 1998 289 319 (in eng)
    • (1998) Annu. Rev. Pharmacol. Toxicol. , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 40
    • 83555168220 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases: More than just kinases and not only for GPCRs. (Translated from eng)
    • (in eng)
    • Gurevich EV, Tesmer JJ, Mushegian A, and Gurevich VV (G protein-coupled receptor kinases: more than just kinases and not only for GPCRs. (Translated from eng), Pharmacol. Ther. 133 (1):40-69 (in eng).
    • Pharmacol. Ther. , vol.133 , Issue.1 , pp. 40-69
    • Gurevich, E.V.1    Tesmer, J.J.2    Mushegian, A.3    Gurevich, V.V.4
  • 41
    • 50449087071 scopus 로고    scopus 로고
    • Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. (Translated from eng)
    • (in eng)
    • J.S. Martini Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. (Translated from eng) Proc. Natl. Acad. Sci. USA 105 34 2008 12457 12462 (in eng)
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.34 , pp. 12457-12462
    • Martini, J.S.1
  • 42
    • 34250828549 scopus 로고    scopus 로고
    • The localization of protein kinase Cdelta in different subcellular sites affects its proapoptotic and antiapoptotic functions and the activation of distinct downstream signaling pathways. (Translated from eng)
    • (in eng)
    • R. Gomel The localization of protein kinase Cdelta in different subcellular sites affects its proapoptotic and antiapoptotic functions and the activation of distinct downstream signaling pathways. (Translated from eng) Mol. Cancer Res. 5 6 2007 627 639 (in eng)
    • (2007) Mol. Cancer Res. , vol.5 , Issue.6 , pp. 627-639
    • Gomel, R.1
  • 43
    • 84873172359 scopus 로고    scopus 로고
    • GRK2 and beta-arrestins in cardiovascular disease: Something old, something new
    • Translated from eng (in eng)
    • Lymperopoulos A (GRK2 and beta-arrestins in cardiovascular disease: Something old, something new. (Translated from eng) Am J, Cardiovasc. Dis. 1 (2):126-137 (in eng).
    • Am J Cardiovasc. Dis. , vol.1 , Issue.2 , pp. 126-137
    • Lymperopoulos, A.1
  • 44
    • 84886236451 scopus 로고    scopus 로고
    • AAV6.BetaARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model (Translated from Eng)
    • Raake PW, et al. (AAV6.betaARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model. (Translated from Eng) Eur. Heart J. (in eng).
    • Eur. Heart J. (In Eng)
    • Raake, P.W.1
  • 45
    • 84876413668 scopus 로고    scopus 로고
    • Prodeath signaling of g protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting. (Translated from eng)
    • (in eng)
    • Chen M, et al. (Prodeath signaling of g protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting. (Translated from eng), Circ. Res. 112 (8):1121-1134 (in eng).
    • Circ. Res. , vol.112 , Issue.8 , pp. 1121-1134
    • Chen, M.1
  • 46
    • 0036009115 scopus 로고    scopus 로고
    • NF-kappaB at the crossroads of life and death. (Translated from eng)
    • (in eng)
    • M. Karin, and A. Lin NF-kappaB at the crossroads of life and death. (Translated from eng) Nat. Immunol. 3 3 2002 221 227 (in eng)
    • (2002) Nat. Immunol. , vol.3 , Issue.3 , pp. 221-227
    • Karin, M.1    Lin, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.