Impaired neoangiogenesis in β2-adrenoceptor gene-deficient mice: Restoration by intravascular human β2-adrenoceptor gene transfer and role of NFkB and CREB transcription factors

British Journal of Pharmacology

Volumn 162, Issue 3, 2011, Pages 712-721

  Ciccarelli, Michele ^a,b   Sorriento, Daniela ^a   Cipolletta, Ersilia ^a   Santulli, Gaetano ^a   Fusco, Anna ^a   Zhou, Rui Hai ^b   Eckhart, Andrea D ^b   Peppel, Karsten ^b   Koch, Walter J ^b   Trimarco, Bruno ^a   Iaccarino, Guido ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

adrenergic signaling; gene therapy; ischaemic hindlimb; NFkB activity

Indexed keywords

ADENOVIRUS VECTOR; BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOPRENALINE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; HINDLIMB; LIMB ISCHEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; VIRAL GENE THERAPY;

ANIMALS; BLOOD FLOW VELOCITY; CELLS, CULTURED; CREB-BINDING PROTEIN; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENE THERAPY; GENETIC VECTORS; HUMANS; ISCHEMIA; LUCIFERASES; MALE; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC; NF-KAPPA B; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 78651417065     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01078.x     Document Type: Article

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