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Volumn 10, Issue 4, 2013, Pages 798-807

Novel Protective Effects of Histone Deacetylase Inhibition on Stroke and White Matter Ischemic Injury

Author keywords

aging; Cerebral ischemia; infarct; mitochondria; p53; Zn dependent histone deacetylase

Indexed keywords

BUTYRIC ACID; GIVINOSTAT; GLUCOSE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; OXYGEN; PROTEIN P53; SHORT HAIRPIN RNA; TRICHOSTATIN A; VALPROIC ACID; VORINOSTAT; ZINC;

EID: 84886300259     PISSN: 19337213     EISSN: 18787479     Source Type: Journal    
DOI: 10.1007/s13311-013-0201-x     Document Type: Review
Times cited : (37)

References (62)
  • 1
    • 84872091789 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2013 update
    • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics-2013 update. Circulation 2013;127: e6-e245.
    • (2013) Circulation , vol.127
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 2
    • 79952602001 scopus 로고    scopus 로고
    • Epigenetic regulation of neurogenesis in the adult mammalian brain
    • Sun J, Sun J, Ming G-l, Song H. Epigenetic regulation of neurogenesis in the adult mammalian brain. Europ J Neurosci 2011;33: 1087-1093.
    • (2011) Europ J Neurosci , vol.33 , pp. 1087-1093
    • Sun, J.1    Sun, J.2    Ming, G.-L.3    Song, H.4
  • 3
    • 79952596383 scopus 로고    scopus 로고
    • The emerging role of epigenetics in stroke. III Neural stem cell biology and regenerative medicine
    • Qureshi IA, Mehler MF. The emerging role of epigenetics in stroke. III Neural stem cell biology and regenerative medicine. Arch Neurol 2011;68: 294-302.
    • (2011) Arch Neurol , vol.68 , pp. 294-302
    • Qureshi, I.A.1    Mehler, M.F.2
  • 4
    • 79952384705 scopus 로고    scopus 로고
    • Cancer epigenetics reaches mainstream oncology
    • Rodríguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat Med 2011;17: 330-339.
    • (2011) Nat Med , vol.17 , pp. 330-339
    • Rodríguez-Paredes, M.1    Esteller, M.2
  • 5
    • 80052266670 scopus 로고    scopus 로고
    • Epigenetics: an expanding new piece of the stroke puzzle
    • Pearce WJ. Epigenetics: an expanding new piece of the stroke puzzle. Transl Stroke Res 2011;2: 243-247.
    • (2011) Transl Stroke Res , vol.2 , pp. 243-247
    • Pearce, W.J.1
  • 6
    • 77952581350 scopus 로고    scopus 로고
    • Long non-coding RNAs in nervous system function and disease
    • Qureshi IA, Mattick JS, Mehler MF. Long non-coding RNAs in nervous system function and disease. Brain Res 2010;1338: 20-35.
    • (2010) Brain Res , vol.1338 , pp. 20-35
    • Qureshi, I.A.1    Mattick, J.S.2    Mehler, M.F.3
  • 7
    • 84866740972 scopus 로고    scopus 로고
    • Effect of focal ischemia on long noncoding RNAs
    • Dharap A, Nakka VP, Vemuganti R. Effect of focal ischemia on long noncoding RNAs. Stroke 2012;43: 2800-2802.
    • (2012) Stroke , vol.43 , pp. 2800-2802
    • Dharap, A.1    Nakka, V.P.2    Vemuganti, R.3
  • 8
    • 84886283181 scopus 로고    scopus 로고
    • Non-coding RNAs as potential neuroprotectants against ischemic brain injury
    • Kaur P, Liu F, Rong et al. Non-coding RNAs as potential neuroprotectants against ischemic brain injury. Brain Sci 2013;3: 360-395.
    • (2013) Brain Sci , vol.3 , pp. 360-395
    • Kaur, P.1    Liu, F.2    Rong3
  • 9
    • 78650112000 scopus 로고    scopus 로고
    • The emerging role of epigenetics in stroke II. RNA regulatory circuitry
    • Qureshi IA, Mehler MF. The emerging role of epigenetics in stroke II. RNA regulatory circuitry. Arch Neurol 2010;67: 1435-1441.
    • (2010) Arch Neurol , vol.67 , pp. 1435-1441
    • Qureshi, I.A.1    Mehler, M.F.2
  • 10
    • 73949091031 scopus 로고    scopus 로고
    • Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures
    • Liu D-Z, Tian Y, Ander BP et al. Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures J Cereb Blood Flow Metab 2010;30: 92-101.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 92-101
    • Liu, D.-Z.1    Tian, Y.2    Ander, B.P.3
  • 11
    • 84876706275 scopus 로고    scopus 로고
    • MicroRNAs: Innovative targets for cerebral ischemia and stroke
    • Ouyang YB, Stary CM, Yang GY, Giffard R. MicroRNAs: Innovative targets for cerebral ischemia and stroke. Curr Drug Targets 2013;14: 90-101.
    • (2013) Curr Drug Targets , vol.14 , pp. 90-101
    • Ouyang, Y.B.1    Stary, C.M.2    Yang, G.Y.3    Giffard, R.4
  • 13
    • 79957649500 scopus 로고    scopus 로고
    • MicroRNA in ischemic stroke etiology and pathology
    • Rink C, Khanna S. MicroRNA in ischemic stroke etiology and pathology. Physiol Genom 2011;43: 521-528.
    • (2011) Physiol Genom , vol.43 , pp. 521-528
    • Rink, C.1    Khanna, S.2
  • 14
    • 78149491805 scopus 로고    scopus 로고
    • Emerging role of epigenetics in stroke. Part 1: DNA methylation and chromatin modifications
    • Qureshi IA, Mehler MF. Emerging role of epigenetics in stroke. Part 1: DNA methylation and chromatin modifications. Arch Neurol 2010;67: 1316-1322.
    • (2010) Arch Neurol , vol.67 , pp. 1316-1322
    • Qureshi, I.A.1    Mehler, M.F.2
  • 15
    • 80052239705 scopus 로고    scopus 로고
    • Expression of histone deacetylases in cellular compartments of the mouse brain and the effects of ischemia
    • Baltan S, Bachleda A, Morrison RS, Murphy SP. Expression of histone deacetylases in cellular compartments of the mouse brain and the effects of ischemia. Trans Stroke Res 2011;2: 411-423.
    • (2011) Trans Stroke Res , vol.2 , pp. 411-423
    • Baltan, S.1    Bachleda, A.2    Morrison, R.S.3    Murphy, S.P.4
  • 16
    • 38949103746 scopus 로고    scopus 로고
    • White matter vulnerability to ischemic injury increases with age due to enhanced excitotoxicity
    • Baltan S, Besancon EF, Mbow B, Ye, ZC, Hamner M, Ransom BR. White matter vulnerability to ischemic injury increases with age due to enhanced excitotoxicity. J Neurosci 2008;28: 1479-1489.
    • (2008) J Neurosci , vol.28 , pp. 1479-1489
    • Baltan, S.1    Besancon, E.F.2    Mbow, B.3    Ye, Z.C.4    Hamner, M.5    Ransom, B.R.6
  • 17
    • 77958544846 scopus 로고    scopus 로고
    • Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies
    • Gibson CL, Murphy SP. Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies. J Neurochem 2010;115: 806-813.
    • (2010) J Neurochem , vol.115 , pp. 806-813
    • Gibson, C.L.1    Murphy, S.P.2
  • 18
    • 78650919356 scopus 로고    scopus 로고
    • Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition
    • Wang Z, Leng Y, Tsai L-K, Leeds P, Chuang D-M. Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition. J Cereb Blood Flow Metab 2011: 31;52-57.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 52-57
    • Wang, Z.1    Leng, Y.2    Tsai, L.-K.3    Leeds, P.4    Chuang, D.-M.5
  • 19
    • 84862824580 scopus 로고    scopus 로고
    • HDAC inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage
    • Wang B, Zhu X, Kim YT, et al. HDAC inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage. Free Rad Biol Med 2012;52: 928-936.
    • (2012) Free Rad Biol Med , vol.52 , pp. 928-936
    • Wang, B.1    Zhu, X.2    Kim, Y.T.3
  • 20
    • 84877015491 scopus 로고    scopus 로고
    • HDAC4/5-HMGB1 signaling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury
    • He M, Zhang B, Wei X, Wang Z, Fan B, Du P, et al. HDAC4/5-HMGB1 signaling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury. J Cell Mol Med 2013;17: 531-542:.
    • (2013) J Cell Mol Med , vol.17 , pp. 531-542
    • He, M.1    Zhang, B.2    Wei, X.3    Wang, Z.4    Fan, B.5    Du, P.6
  • 21
    • 0028923459 scopus 로고
    • Why do all drugs work in animals but none in stroke patients? 1. Drugs promoting cerebral blood flow
    • Del Zoppo GJ. Why do all drugs work in animals but none in stroke patients? 1. Drugs promoting cerebral blood flow. J Intern Med 1995;237: 79-88.
    • (1995) J Intern Med , vol.237 , pp. 79-88
    • Del Zoppo, G.J.1
  • 22
    • 0031685142 scopus 로고    scopus 로고
    • Clinical trials in acute stroke: why have they not been successful?
    • Del Zoppo GJ. Clinical trials in acute stroke: why have they not been successful? Neurology 1998;51: S59-S61.
    • (1998) Neurology , vol.51
    • Del Zoppo, G.J.1
  • 23
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999;22: 391-397.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 27
    • 79952759556 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors preserve white matter structure and function during ischemia by conserving ATP and reducing excitotoxicity
    • Baltan S, Murphy SP, Danilov AC, Bachleda A, Morrison R. Histone deacetylase inhibitors preserve white matter structure and function during ischemia by conserving ATP and reducing excitotoxicity. J Neurosci 2011;31: 3990-3999.
    • (2011) J Neurosci , vol.31 , pp. 3990-3999
    • Baltan, S.1    Murphy, S.P.2    Danilov, A.C.3    Bachleda, A.4    Morrison, R.5
  • 28
    • 84867543740 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors preserve function in aging axons
    • Baltan S. Histone deacetylase inhibitors preserve function in aging axons. J Neurochem 2012;123(Suppl. 2): 108-115.
    • (2012) J Neurochem , vol.123 , Issue.SUPPL. 2 , pp. 108-115
    • Baltan, S.1
  • 29
    • 63349104552 scopus 로고    scopus 로고
    • Ischemic injury to white matter: An age-dependent process
    • Baltan S. Ischemic injury to white matter: An age-dependent process. Neuroscientist 2009;15: 126-133.
    • (2009) Neuroscientist , vol.15 , pp. 126-133
    • Baltan, S.1
  • 30
    • 34250720823 scopus 로고    scopus 로고
    • Excitotoxic mechanisms of ischemic injury in myelinated white matter
    • Tekkok SB, Ye ZC, Ransom BR. Excitotoxic mechanisms of ischemic injury in myelinated white matter. J Cereb Blood Flow Metab 2007;27: 1540-1552.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1540-1552
    • Tekkok, S.B.1    Ye, Z.C.2    Ransom, B.R.3
  • 31
    • 13344286293 scopus 로고    scopus 로고
    • Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
    • Rothstein JD, Dykes-Hoberg M, Pardo CA, et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 1996;16: 675-686.
    • (1996) Neuron , vol.16 , pp. 675-686
    • Rothstein, J.D.1    Dykes-Hoberg, M.2    Pardo, C.A.3
  • 32
    • 0028923784 scopus 로고
    • A BDNF autocrine loop in adult sensory neurons prevents cell death
    • Acheson A, Conover JC, Fandl JP, et al. A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature 1995;374: 450-453.
    • (1995) Nature , vol.374 , pp. 450-453
    • Acheson, A.1    Conover, J.C.2    Fandl, J.P.3
  • 33
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • Huang EJ, Reichardt LF. Neurotrophins: Roles in neuronal development and function. Annu Rev Neurosci 2001;24: 677-736.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 34
    • 58049196879 scopus 로고    scopus 로고
    • The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons
    • Yasuda S, Liang MH, Marinova Z, Yahyavi A, Chuang DM. The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons. Mol Psych 2009;14: 51-59.
    • (2009) Mol Psych , vol.14 , pp. 51-59
    • Yasuda, S.1    Liang, M.H.2    Marinova, Z.3    Yahyavi, A.4    Chuang, D.M.5
  • 35
    • 84864746911 scopus 로고    scopus 로고
    • Valproic acid increases white matter repair and neurogenesis after stroke
    • Liu XS, Chopp M, Kassis H, et al. Valproic acid increases white matter repair and neurogenesis after stroke. Neuroscience 2012;220: 313-321.
    • (2012) Neuroscience , vol.220 , pp. 313-321
    • Liu, X.S.1    Chopp, M.2    Kassis, H.3
  • 36
    • 84865595109 scopus 로고    scopus 로고
    • Chronic valproate treatment enhances postischemic angiogenesis and promotes functional recovery in a rat model of ischemic stroke
    • Wang Z, Tsai LK, Munasinghe J, et al. Chronic valproate treatment enhances postischemic angiogenesis and promotes functional recovery in a rat model of ischemic stroke. Stroke 2012;43: 2430-2436.
    • (2012) Stroke , vol.43 , pp. 2430-2436
    • Wang, Z.1    Tsai, L.K.2    Munasinghe, J.3
  • 37
    • 84866387948 scopus 로고    scopus 로고
    • Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity
    • Fass DM, Reis SA, et al. Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology 2013;64: 81-96.
    • (2013) Neuropharmacology , vol.64 , pp. 81-96
    • Fass, D.M.1    Reis, S.A.2
  • 38
    • 83755224359 scopus 로고    scopus 로고
    • Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage
    • Chen SH, Wu HM, Ossola B, et al. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage. Br J Pharmacol 2012;165: 494-505.
    • (2012) Br J Pharmacol , vol.165 , pp. 494-505
    • Chen, S.H.1    Wu, H.M.2    Ossola, B.3
  • 40
    • 75949124394 scopus 로고    scopus 로고
    • Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia
    • Son TG, Camandola S, Arumugam TV, et al. Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia. J Neurochem 2010;112: 1316-1326.
    • (2010) J Neurochem , vol.112 , pp. 1316-1326
    • Son, T.G.1    Camandola, S.2    Arumugam, T.V.3
  • 42
    • 36048973184 scopus 로고    scopus 로고
    • Apoptotic actions of p53 require transcriptional activation of PUMA and do not involve a direct mitochondrial/cytoplasmic site of action in postnatal cortical neurons
    • Uo T, Kinoshita Y, Morrison RS. Apoptotic actions of p53 require transcriptional activation of PUMA and do not involve a direct mitochondrial/cytoplasmic site of action in postnatal cortical neurons. J Neurosci 2007;27: 12198-12210.
    • (2007) J Neurosci , vol.27 , pp. 12198-12210
    • Uo, T.1    Kinoshita, Y.2    Morrison, R.S.3
  • 43
    • 38149116286 scopus 로고    scopus 로고
    • Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21waf1/cip1 in cell cycle-independent neuroprotection
    • Langley B, D'Annibale MA, Suh K, et al. Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21waf1/cip1 in cell cycle-independent neuroprotection. J Neurosci 2008;28: 163-176.
    • (2008) J Neurosci , vol.28 , pp. 163-176
    • Langley, B.1    D'Annibale, M.A.2    Suh, K.3
  • 44
    • 77956525855 scopus 로고    scopus 로고
    • HDAC6 regulates mitochondrial transport in hippocampal neurons
    • Chen S, Owens GC, Makarenkova H, Edelman DB. HDAC6 regulates mitochondrial transport in hippocampal neurons. PLoS One 2010;5: e10848.
    • (2010) PLoS One , vol.5
    • Chen, S.1    Owens, G.C.2    Makarenkova, H.3    Edelman, D.B.4
  • 45
    • 34047175919 scopus 로고    scopus 로고
    • Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation
    • Dompierre JP, Godin JD, Charrin BC, Cordelières FP, et al. Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation. J Neurosci 2007;27: 3571-3583.
    • (2007) J Neurosci , vol.27 , pp. 3571-3583
    • Dompierre, J.P.1    Godin, J.D.2    Charrin, B.C.3    Cordelières, F.P.4
  • 46
    • 75549089982 scopus 로고    scopus 로고
    • HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage
    • Kim JY, Shen S, Dietz K, He Y, Reynolds R, Casaccia P. HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. Nat Neurosci 2010;13: 180-189.
    • (2010) Nat Neurosci , vol.13 , pp. 180-189
    • Kim, J.Y.1    Shen, S.2    Dietz, K.3    He, Y.4    Reynolds, R.5    Casaccia, P.6
  • 47
    • 84872737271 scopus 로고    scopus 로고
    • Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death
    • Wang DB, Garden GA, Kinoshita C, et al. Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death. J Neurosci 2013;33: 1357-1365.
    • (2013) J Neurosci , vol.33 , pp. 1357-1365
    • Wang, D.B.1    Garden, G.A.2    Kinoshita, C.3
  • 48
    • 63849206749 scopus 로고    scopus 로고
    • HDAC inhibitors prevent p53-dependent and -independent Bax-mediate neuronal apoptosis through two distinct mechanisms
    • Uo T, Veenstra TD, Morrison RS. HDAC inhibitors prevent p53-dependent and -independent Bax-mediate neuronal apoptosis through two distinct mechanisms. J Neurosci 2009;29: 2824-2832.
    • (2009) J Neurosci , vol.29 , pp. 2824-2832
    • Uo, T.1    Veenstra, T.D.2    Morrison, R.S.3
  • 49
    • 70350133780 scopus 로고    scopus 로고
    • Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation
    • Marinova Z, Ren M, Wendland JR, Leng Y, et al. Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation. J Neurochem 2009;111: 976-987.
    • (2009) J Neurochem , vol.111 , pp. 976-987
    • Marinova, Z.1    Ren, M.2    Wendland, J.R.3    Leng, Y.4
  • 50
    • 40449135649 scopus 로고    scopus 로고
    • Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition
    • Leng Y, Liang MH, Ren M, et al. Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition. J Neurosci 2008;28: 2576-2588.
    • (2008) J Neurosci , vol.28 , pp. 2576-2588
    • Leng, Y.1    Liang, M.H.2    Ren, M.3
  • 51
    • 26844518082 scopus 로고    scopus 로고
    • Intracellular trafficking of histone deacetylase 4 regulates neuronal cell death
    • Bolger TA, Yao TP. Intracellular trafficking of histone deacetylase 4 regulates neuronal cell death. J Neurosci 2005;25: 9544-9553.
    • (2005) J Neurosci , vol.25 , pp. 9544-9553
    • Bolger, T.A.1    Yao, T.P.2
  • 52
    • 79960331579 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ is inhibited by histone deacetylase 4 in cortical neurons under oxidative stress
    • Yang Y, Qin X, Liu S, et al. Peroxisome proliferator-activated receptor γ is inhibited by histone deacetylase 4 in cortical neurons under oxidative stress. J Neurochem 2011;118: 429-439.
    • (2011) J Neurochem , vol.118 , pp. 429-439
    • Yang, Y.1    Qin, X.2    Liu, S.3
  • 53
    • 84877275312 scopus 로고    scopus 로고
    • Neuronal restoration following ischemic stroke: influences, barriers, and therapeutic potential
    • Kahle MP, Bix GJ. Neuronal restoration following ischemic stroke: influences, barriers, and therapeutic potential. Neurorehabil Neural Repair 2013;27: 469-478.
    • (2013) Neurorehabil Neural Repair , vol.27 , pp. 469-478
    • Kahle, M.P.1    Bix, G.J.2
  • 54
    • 9344252804 scopus 로고    scopus 로고
    • Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
    • Hsieh J, Nakashima K, Kuwabara T, Mejia E, Gage FH Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci USA 2004;101: 16659-16664.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16659-16664
    • Hsieh, J.1    Nakashima, K.2    Kuwabara, T.3    Mejia, E.4    Gage, F.H.5
  • 55
    • 34447343304 scopus 로고    scopus 로고
    • Effects of HDAC inhibition on neuronal differentiation of embryonic mouse neural stem cells
    • Balasubramaniyan V, Boddeke E, Bakels R Effects of HDAC inhibition on neuronal differentiation of embryonic mouse neural stem cells. Neuroscience 2006: 143; 939-951.
    • (2006) Neuroscience , vol.143 , pp. 939-951
    • Balasubramaniyan, V.1    Boddeke, E.2    Bakels, R.3
  • 56
    • 77952348698 scopus 로고    scopus 로고
    • Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation
    • Dovey OM, Foster CT, Cowley SM. Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation. Proc Natl Acad Sci U S A 2010;107: 8242-8247.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 8242-8247
    • Dovey, O.M.1    Foster, C.T.2    Cowley, S.M.3
  • 57
    • 76749144535 scopus 로고    scopus 로고
    • Crucial roles of histone-modifying enzymes in mediating neural cell-type specification
    • Lee S, Lee S-K. Crucial roles of histone-modifying enzymes in mediating neural cell-type specification. Curr Opin Neurobiol 2010;20: 29-36.
    • (2010) Curr Opin Neurobiol , vol.20 , pp. 29-36
    • Lee, S.1    Lee, S.-K.2
  • 59
    • 42049099275 scopus 로고    scopus 로고
    • Complementary roles for HDACs 1,2,and 3 in differentiation of pluripotent stem cells
    • Humphrey GW, Wang Y-H, Hirai T, et al. Complementary roles for HDACs 1, 2, and 3 in differentiation of pluripotent stem cells. Differentiation 2008;76: 348-356.
    • (2008) Differentiation , vol.76 , pp. 348-356
    • Humphrey, G.W.1    Wang, Y.-H.2    Hirai, T.3
  • 60
    • 34248530339 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action
    • Kim H J, Rowe M, Ren M, Hong J-S, Chen P-S, Chuang D-M. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther 2007;321: 892-901.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 892-901
    • Kim, H.J.1    Rowe, M.2    Ren, M.3    Hong, J.-S.4    Chen, P.-S.5    Chuang, D.-M.6
  • 61
    • 65549123471 scopus 로고    scopus 로고
    • HDAC2 negatively regulates memory formation and synaptic plasticity
    • Guan J-S, Haggarty SJ, Giacometti E, et al. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 2009;459: 55-60.
    • (2009) Nature , vol.459 , pp. 55-60
    • Guan, J.-S.1    Haggarty, S.J.2    Giacometti, E.3
  • 62
    • 52149108919 scopus 로고    scopus 로고
    • S-nitrosylation of HDAC2 induces chromatin remodeling in neurons
    • Nott A, Watson PM, Robinson JD, Crepaldi L, Riccio A. S-nitrosylation of HDAC2 induces chromatin remodeling in neurons. Nature 2008;455: 411-415.
    • (2008) Nature , vol.455 , pp. 411-415
    • Nott, A.1    Watson, P.M.2    Robinson, J.D.3    Crepaldi, L.4    Riccio, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.