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Volumn 19, Issue 14, 2011, Pages 4377-4385

Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP

(8) Kawamura, Tatsuro a Matsubara, Kohei a Otaka, Hitomi a Tashiro, Etsu a Shindo, Kazutoshi b Yanagita, Ryo C c Irie, Kazuhiro c Imoto, Masaya a

a KEIO UNIVERSITY (Japan)

b JAPAN WOMEN'S UNIVERSITY (Japan)

c KYOTO UNIVERSITY (Japan)

Author keywords

C38OX6; Cancer; Chemical library; Natural product; Unnatural Natural Product; XIAP

Indexed keywords

ANTINEOPLASTIC AGENT; C 38OX6; CASPASE 3; PROTEIN INHIBITOR; PROTEIN KINASE C; TELEOCIDIN B; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; X LINKED INHIBITOR OF APOPTOSIS INHIBITOR;

ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DIODE; DRUG IDENTIFICATION; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG PURIFICATION; DRUG SENSITIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MOLECULAR LIBRARY; PROTEIN PROTEIN INTERACTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL AGENTS; CASPASE 3; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; HELA CELLS; HUMANS; IMIDES; INDOLE ALKALOIDS; LYNGBYA TOXINS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 79959929573 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.05.009 Document Type: Article

Times cited : (29)

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