Improved accuracy of low affinity protein-ligand equilibrium dissociation constants directly determined by electrospray ionization mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 5, 2012, Pages 908-922

  Jaquillard, Lucie ^a   Saab, Fabienne ^a   Schoentgen, Françoise ^b   Cadene, Martine ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

Author keywords

Accuracy; Aggregation; Equilibrium dissociation constant; ESI; Gas phase dissociation; Interaction; KD; Low affinity; Mass spectrometry; Model; Protein ligand

Indexed keywords

ACCURACY; EQUILIBRIUM DISSOCIATION CONSTANT; ESI; GAS-PHASE DISSOCIATION; INTERACTION; KD; LOW AFFINITY; PROTEIN-LIGAND;

AGGLOMERATION; COMPLEXATION; MASS SPECTROMETRY; MATHEMATICAL MODELS; MODELS;

DISSOCIATION;

LIGAND; PROTEIN;

ACCURACY; ARTICLE; DISSOCIATION CONSTANT; ELECTROSPRAY MASS SPECTROMETRY; FILTRATION; GAS; GEL FILTRATION; KINETICS; MATHEMATICAL MODEL; MEASUREMENT; MOLECULAR INTERACTION; VALIDATION PROCESS;

ANIMALS; CATTLE; CHICKENS; GASES; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; NUCLEOTIDES; PROTEIN BINDING; PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84862515709     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0305-7     Document Type: Article

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