Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Shao, Weijuan ^a   Yu, Zhiwen ^b   Chiang, Yuting ^a,c   Yang, Yi ^a,e   Chai, Tuanyao ^a   Foltz, Warren ^d   Lu, Huogen ^a,c   Fantus, I George ^a,c   Jin, Tianru ^a,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

^e NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMIN; GLUCOSE; PYRUVIC ACID; WNT PROTEIN; INSULIN; PROTEIN KINASE B;

ADIPOCYTE; ADIPOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL LINEAGE; CONTROLLED STUDY; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPOGENESIS; MACROPHAGE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WEIGHT GAIN; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; CELL STRAIN HEPG2; DIET SUPPLEMENTATION; DRUG EFFECT; FAT INTAKE; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; LIVER; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RAT; TIME;

MUS; RATTUS;

ADIPOCYTES; ADIPOSE TISSUE; ADIPOSITY; ANIMALS; CURCUMIN; DIETARY FATS; DIETARY SUPPLEMENTS; GENE EXPRESSION REGULATION; GLUCOSE; HEP G2 CELLS; HUMANS; INFLAMMATION; INSULIN; INSULIN RESISTANCE; LIPOGENESIS; LIVER; MALE; MICE; MICE, INBRED C57BL; OBESITY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION; TIME FACTORS; WEIGHT GAIN;

EID: 84855503887     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028784     Document Type: Article

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