Assessment of the matrix degenerative Effects of MMP-3, ADAMTS-4, and HTRA1, injected into a bovine intervertebral disc organ culture model

Spine

Volumn 38, Issue 22, 2013, Pages

  Furtwängler, Tina ^a   Chan, Samantha C W ^a   Bahrenberg, Gregor ^b   Richards, Peter J ^b   Gantenbein Ritter, Benjamin ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

ADAMTS 4; cattle; DNA; gene expression; histology.; HO proline; HTRA1; intervertebral disc degeneration; large animal model; metalloproteinase 3; organ culture; proteoglycan

Indexed keywords

AGGRECANASE 1; COLLAGEN; DNA; GLYCOSAMINOGLYCAN; HTRA1 PROTEIN; PAPAIN; SERINE PROTEINASE; STROMELYSIN; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; COW; ENZYME STRUCTURE; GENE EXPRESSION; IN VITRO STUDY; INJECTION; INTERVERTEBRAL DISK DEGENERATION; NONHUMAN; NUCLEUS PULPOSUS; ORGAN CULTURE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; TISSUE SECTION;

ADAM PROTEINS; ANIMALS; CATTLE; COLLAGEN; DISEASE MODELS, ANIMAL; DNA; GENE EXPRESSION; GLYCOSAMINOGLYCANS; HUMANS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 3; ORGAN CULTURE TECHNIQUES; PROCOLLAGEN N-ENDOPEPTIDASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERINE ENDOPEPTIDASES; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-3;

EID: 84886098562     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e31829ffde8     Document Type: Article

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