Development of an in vitro model to test the efficacy of novel therapies for IVD degeneration

Journal of Tissue Engineering and Regenerative Medicine

Volumn 3, Issue 6, 2009, Pages 461-469

  Le Maitre, Christine L ^a   Fotheringham, Andrew P ^b   Freemont, Anthony J ^b   Hoyland, Judith A ^b  

^a SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Culture system; Intervertebral disc; Loading; Low back pain; Therapeutic testing; Tissue culture

Indexed keywords

CELL ENGINEERING; METABOLISM; TISSUE; TISSUE ENGINEERING;

CULTURE SYSTEMS; HUMAN SPINE; IN-VITRO MODELS; IN-VIVO; INTER-VERTEBRAL DISC DEGENERATION; INTERVERTEBRAL DISC TISSUES; INTERVERTEBRAL DISK; LOADING ENVIRONMENT; LOWER BACK PAIN; THERAPEUTIC TESTING;

TISSUE CULTURE;

GLYCOSAMINOGLYCAN; MESSENGER RNA; PROTEOGLYCAN; AGGRECAN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; POLYADENYLIC ACID;

ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CELL METABOLISM; CELL THERAPY; CONTROLLED STUDY; COW; EXPLANT; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; LOADING TEST; LOW BACK PAIN; NONHUMAN; NUCLEUS PULPOSUS; PHENOTYPE; PRIORITY JOURNAL; TISSUE CULTURE; TISSUE ENGINEERING; TISSUE REGENERATION; ANIMAL; BIOLOGICAL MODEL; CATTLE; GENETICS; HUMAN; HYDROSTATIC PRESSURE; INTERVERTEBRAL DISK HERNIA; METABOLISM; METHODOLOGY;

AGGRECANS; ANIMALS; CATTLE; COLLAGEN TYPE I; COLLAGEN TYPE II; HUMANS; HYDROSTATIC PRESSURE; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISK DISPLACEMENT; MODELS, BIOLOGICAL; PHENOTYPE; POLY A; PROTEOGLYCANS; TISSUE ENGINEERING;

EID: 70350732694     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.180     Document Type: Article

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