TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth

Oncogene

Volumn 32, Issue 42, 2013, Pages 5038-5047

  Di, K ^a   Linskey, M E ^a,b   Bota, D A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

EGFR; Malignant glioma; Oncogene; TRIM11; Tumor formation

Indexed keywords

CD133 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NESTIN; TRIPARTITE MOTIF CONTAINING PROTEIN 11; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GENE OVEREXPRESSION; GLIOBLASTOMA; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUSE; NEURAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIMARY CULTURE; PRIORITY JOURNAL; RNA INTERFERENCE; TUMOR GROWTH; UPREGULATION; WESTERN BLOTTING;

ADULT; AGED; ANIMALS; ANTIGENS, CD; BRAIN NEOPLASMS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN D1; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GLIOBLASTOMA; GLIOMA; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; NESTIN; ONCOGENES; PEPTIDES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UBIQUITIN-PROTEIN LIGASES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84886094506     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.531     Document Type: Article

References (46)

1. Gladson CL, Prayson RA, Liu WM. The pathobiology of glioma tumors. Annu Rev Pathol 2010; 5: 33-50.
2. Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008; 359: 492-507.
3. von Deimling A, Korshunov A, Hartmann C. The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations. Brain Pathol 2011; 21: 74-87.
4. Ma YH, Mentlein R, Knerlich F, Kruse ML, Mehdorn HM, Held-Feindt J. Expression of stem cell markers in human astrocytomas of different WHO grades. J Neurooncol 2008; 86: 31-45. (Pubitemid 350263430)
5. Zhang M, Song T, Yang L, Chen R, Wu L, Yang Z et al. Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients. J Exp Clin Cancer Res 2008; 27: 85.
6. Singh S, Clarke I, Terasaki M, Bonn V, Hawkins C, Squire J et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003; 63: 5821-5828. (Pubitemid 37187480)
7. Singh S, Hawkins C, Clarke I, Squire J, Bayani J, Hide T et al. Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401. (Pubitemid 39551674)
8. Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG et al. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 2012; 488: 522-526.
9. Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006; 444: 756-760. (Pubitemid 44949604)
10. Li Z, Wang H, Eyler CE, Hjelmeland AB, Rich JN. Turning cancer stem cells inside out: an exploration of glioma stem cell signaling pathways. J Biol Chem 2009; 284: 16705-16709.
11. Dey M, Ulasov IV, Tyler MA, Sonabend AM, Lesniak MS. Cancer stem cells: the final frontier for glioma virotherapy. Stem Cell Rev 2011; 7: 119-129.
12. Uchida N, Buck DW, He D, Reitsma MJ, Masek M, Phan TV et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci USA 2000; 97: 14720-14725. (Pubitemid 32016642)
13. Zimmerman L, Parr B, Lendahl U, Cunningham M, McKay R, Gavin B et al. Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron 1994; 12: 11-24. (Pubitemid 24044383)
14. Gong X, Schwartz PH, Linskey ME, Bota DA. Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy. Neurology 2011; 76: 1126-1134.
15. Schmidinger M, Linzmayer L, Becherer A, Fazeny-Doemer B, Fakhrai N, Prayer D et al. Psychometric- and quality-of-life assessment in long-term glioblastoma survivors. J Neurooncol 2003; 63: 55-61. (Pubitemid 36681643)
16. Corn BW, Wang M, Fox S, Michalski J, Purdy J, Simpson J et al. Health related quality of life and cognitive status in patients with glioblastoma multiforme receiving escalating doses of conformal three dimensional radiation on RTOG 98-03. J Neurooncol 2009; 95: 247-257.
17. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L et al. The tripartite motif family identifies cell compartments. EMBO J 2001; 20: 2140-2151. (Pubitemid 32410584)
18. Saurin AJ, Borden KL, Boddy MN, Freemont PS. Does this have a familiar RING? Trends Biochem Sci 1996; 21: 208-214. (Pubitemid 26191224)
19. Borden KL. RING fingers and B-boxes: zinc-binding protein-protein interaction domains. Biochem Cell Biol 1998; 76: 351-358. (Pubitemid 29102020)
20. Hatakeyama S. TRIM proteins and cancer. Nat Rev Cancer 2011; 11: 792-804.
21. Niikura T, Hashimoto Y, Tajima H, Ishizaka M, Yamagishi Y, Kawasumi M et al. A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease-relevant insults. Eur J Neurosci 2003; 17: 1150-1158. (Pubitemid 36459769)
22. Ishikawa H, Tachikawa H, Miura Y, Takahashi N. TRIM11 binds to and destabilizes a key component of the activator-mediated cofactor complex (ARC105) through the ubiquitin-proteasome system. FEBS Lett 2006; 580: 4784-4792. (Pubitemid 44286834)
23. Tuoc TC, Stoykova A. Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system. Genes Dev 2008; 22: 1972-1986. (Pubitemid 352008644)
24. Hong SJ, Chae H, Lardaro T, Hong S, Kim KS. Trim11 increases expression of dopamine beta-hydroxylase gene by interacting with Phox2b. Biochem Biophys Res Commun 2008; 368: 650-655.
25. Sanai N, Alvarez-Buylla A, Berger MS. Neural stem cells and the origin of gliomas. N Engl J Med 2005; 353: 811-822.
26. Schwartz PH, Bryant PJ, Fuja TJ, Su H, O'Dowd DK, Klassen H. Isolation and characterization of neural progenitor cells from post-mortem human cortex. J Neurosci Res 2003; 74: 838-851. (Pubitemid 37490416)
27. Kurihara H, Zama A, Tamura M, Takeda J, Sasaki T, Takeuchi T. Glioma/glioblastoma-specific adenoviral gene expression using the nestin gene regulator. Gene Ther 2000; 7: 686-693. (Pubitemid 30255773)
28. Griguer CE, Oliva CR, Gobin E, Marcorelles P, Benos DJ, Lancaster Jr. JR et al. CD133 is a marker of bioenergetic stress in human glioma. PLoS One 2008; 3: e3655.
29. Zhou XD, Wang XY, Qu FJ, Zhong YH, Lu XD, Zhao P et al. Detection of cancer stem cells from the C6 glioma cell line. J Int Med Res 2009; 37: 503-510.
30. Lim DA, Cha S, Mayo MC, Chen MH, Keles E, Vanden Berg S et al. Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype. Neuro Oncol 2007; 9: 424-429.
31. Rao RD, Uhm JH, Krishnan S, James CD. Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies. Front Biosci 2003; 8: e270-e280.
32. Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007; 26: 3291-3310. (Pubitemid 46763022)
33. Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2000; 103: 211-225.
34. Eramo A, Ricci-Vitiani L, Zeuner A, Pallini R, Lotti F, Sette G et al. Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ 2006; 13: 1238-1241. (Pubitemid 43905604)
35. Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell 2008; 132: 645-660. (Pubitemid 351253687)
36. Kordes C, Sawitza I, Muller-Marbach A, Ale-Agha N, Keitel V, Klonowski-Stumpe H et al. CD133+ hepatic stellate cells are progenitor cells. Biochem Biophys Res Commun 2007; 352: 410-417. (Pubitemid 44838502)
37. Sherman JH, Redpath GT, Redick JA, Purow BW, Laws ER, Jane Jr JA et al. A novel fixative for immunofluorescence staining of CD133-positive glioblastoma stem cells. J Neurosci Methods 2011; 198: 99-102.
38. Fredens K, Dahl R, Venge P. An immunofluorescent method for a specific demonstration of granulocytes and some of their proteins (ECP and CCP). Histochemistry 1986; 84: 247-250. (Pubitemid 16141200)
39. Bigner SH, Humphrey PA, Wong AJ, Vogelstein B, Mark J, Friedman HS et al. Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts. Cancer Res 1990; 50: 8017-8022.
40. Raab G, Klagsbrun M. Heparin-binding EGF-like growth factor. Biochim Biophys Acta 1997; 1333: F179-F199. (Pubitemid 28015313)
41. Suo Z, Risberg B, Karlsson MG, Villman K, Skovlund E, Nesland JM. The expression of EGFR family ligands in breast carcinomas. Int J Surg Pathol 2002; 10: 91-99. (Pubitemid 34655095)
42. Tarbe N, Losch S, Burtscher H, Jarsch M, Weidle UH. Identification of rat pancreatic carcinoma genes associated with lymphogenous metastasis. Anticancer Res 2002; 22: 2015-2027. (Pubitemid 34857018)
43. Mishima K, Higashiyama S, Asai A, Yamaoka K, Nagashima Y, Taniguchi N et al. Heparin-binding epidermal growth factor-like growth factor stimulates mitogenic signaling and is highly expressed in human malignant gliomas. Acta Neuropathol 1998; 96: 322-328. (Pubitemid 28451136)
44. McCarthy SA, Samuels ML, Pritchard CA, Abraham JA, McMahon M. Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes. Genes Dev 1995; 9: 1953-1964.
45. Ongusaha PP, Kwak JC, Zwible AJ, Macip S, Higashiyama S, Taniguchi N et al. HBEGF is a potent inducer of tumor growth and angiogenesis. Cancer Res 2004; 64: 5283-5290. (Pubitemid 39006548)
46. Pistollato F, Chen H-L, Rood BR, Zhang H-Z, D'Avella D, Denaro L et al. Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma. Stem Cells 2009; 27: 7-17.