Editorial: Memory CD8 T cells now join "Club 21"

Journal of Leukocyte Biology

Volumn 87, Issue 1, 2010, Pages 13-15

  Tagaya, Yutaka ^a  

^a Dermaheal USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 21; INTERLEUKIN 7; STAT3 PROTEIN;

CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CYTOLOGY; HOMEOSTASIS; HUMAN; MEMORY T LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKINS; MICE; MICE, KNOCKOUT; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTE SUBSETS; TRANSLATIONAL RESEARCH; X-LINKED COMBINED IMMUNODEFICIENCY DISEASES;

EID: 74949118308     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0909597     Document Type: Review

References (13)

1. Nguyen, H., Weng, N-P. (2009) IL-21 preferentially enhances IL-15 mediated homeostatic proliferation of human CD28+CD8 memory T cells throughout the adult age span. J. Leukoc. Biol.
2. Spolski, R., Leonard, W. J. (2008) The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer. Curr. Opin. Immunol. 20, 295-301.
3. Ozaki, K., Spolski, R., Feng, C. G., Qi, C. F., Cheng, J., Sher, A., Morse III, H. C., Liu, C., Schwartzberg, P. L., Leonard, W. J. (2002) A critical role for IL-21 in regulating immunoglobulin production. Science 298, 1630-1634.
4. Zhou, L., Ivanov, I. I., Spolski, R., Min, R., Shenderov, K., Egawa, T., Levy, D. E., Leonard, W. J., Littman, D. R. (2007) IL-6 promotes T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 8, 967-974.
5. + T cell expansion and function. J. Exp. Med. 201, 139-148.
6. + memory T cell accumulation. Eur. J. Immunol. 37, 3069-3077.
7. Elsaesser, H., Sauer, K., Brooks, D. G. (2009) IL-21 is required to control chronic viral infection. Science 324, 1569-1572.
8. Yi, J. S., Du, M., Zajac, A. J. (2009) A vital role for interleukin-21 in the control of a chronic viral infection. Science 324, 1572-1576.
9. Frohlich, A., Kisielow, J., Schmitz, I., Freigang, S., Shamshiev, A. T., Weber, J., Marsland, B. J., Oxenius, A., Kopf, M. (2009) IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science 324, 1576-1580.
10. Boesteanu, A. C., Katsikis, P. D. (2009) Memory T cells need CD28 costimulation to remember. Semin. Immunol. 21, 69-77.
11. Rochman, Y., Spolski, R., Leonard, W. J. (2009) New insights into the regulation of T cells by γc-family cytokines. Nat. Rev. Immunol. 9, 480-490.
12. Zeng, R., Spolski, R., Casas, E., Zhu, W., Levy, D. E., Leonard, W. J. (2007) The molecular basis of IL-21-mediated proliferation. Blood 109, 4135-4142.
13. Hankey, P. A. (2009) Regulation of hematopoietic cell development and function by Stat3. Front. Biosci. 14, 5273-5290.