메뉴 건너뛰기




Volumn 16, Issue 5, 2013, Pages 386-395

A natural product telomerase activator as part of a health maintenance program: Metabolic and cardiovascular response

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHOLESTEROL; ENZYME ACTIVATOR; FOLIC ACID; GLUCOSE; HOMOCYSTEINE; INSULIN; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; MULTIVITAMIN; NITRIC OXIDE; PRASTERONE SULFATE; TA 65; TELOMERASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VITAMIN D;

EID: 84886018077     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2013.1430     Document Type: Article
Times cited : (74)

References (51)
  • 2
    • 84855481195 scopus 로고    scopus 로고
    • Telomeres and lifestyle factors: Roles in cellular aging
    • Lin J, Epel E, Blackburn E. Telomeres and lifestyle factors: Roles in cellular aging. Mutat Res 2012;730:85-89.
    • (2012) Mutat Res , vol.730 , pp. 85-89
    • Lin, J.1    Epel, E.2    Blackburn, E.3
  • 3
    • 84872054447 scopus 로고    scopus 로고
    • Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis
    • Kropski JA, Lawson WE, Young LR, Blackwell TS. Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. Disease Models Mech 2013;6:9-17.
    • (2013) Disease Models Mech , vol.6 , pp. 9-17
    • Kropski, J.A.1    Lawson, W.E.2    Young, L.R.3    Blackwell, T.S.4
  • 4
    • 84863641682 scopus 로고    scopus 로고
    • Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes
    • Aubert G, Baerlocher GM, Vulto I, Poon SS, Lansdorp PM. Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes. PLoS Genet 2012;8:e1002696.
    • (2012) PLoS Genet , vol.8
    • Aubert, G.1    Baerlocher, G.M.2    Vulto, I.3    Poon, S.S.4    Lansdorp, P.M.5
  • 5
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990;345:458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 9
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB, Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992;11: 1921-1929.
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    Lefeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 11
    • 0028198679 scopus 로고
    • Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
    • Counter CM, Botelho FM, Wang P, Harley CB, Bacchetti S. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. J Virol 1994; 68:3410-3414. (Pubitemid 24129794)
    • (1994) Journal of Virology , vol.68 , Issue.5 , pp. 3410-3414
    • Counter, C.M.1    Botelho, F.M.2    Wang, P.3    Harley, C.B.4    Bacchetti, S.5
  • 13
    • 74049111326 scopus 로고    scopus 로고
    • Telomeres and telomerase in cancer
    • Artandi SE, DePinho RA. Telomeres and telomerase in cancer. Carcinogenesis 2010;31:9-18.
    • (2010) Carcinogenesis , vol.31 , pp. 9-18
    • Artandi, S.E.1    Depinho, R.A.2
  • 14
    • 77950265945 scopus 로고    scopus 로고
    • Linking functional decline of telomeres, mitochondria and stem cells during ageing
    • Sahin E, Depinho RA. Linking functional decline of telomeres, mitochondria and stem cells during ageing. Nature 2010;464:520-528.
    • (2010) Nature , vol.464 , pp. 520-528
    • Sahin, E.1    Depinho, R.A.2
  • 15
    • 71149093724 scopus 로고    scopus 로고
    • How telomeres solve the end-protection problem
    • de Lange T. How telomeres solve the end-protection problem. Science 2009;326:948-952.
    • (2009) Science , vol.326 , pp. 948-952
    • De Lange, T.1
  • 16
    • 77949332406 scopus 로고    scopus 로고
    • Efficacy of rosuvastatin among men and women with moderate chronic kidney disease and elevated high-sensitivity C-reactive protein: A secondary analysis from the JUPITER (Justification for the Use of Statins in Prevention-an Intervention Trial Evaluating Rosuvastatin) trial
    • Ridker PM, MacFadyen J, Cressman M, Glynn RJ. Efficacy of rosuvastatin among men and women with moderate chronic kidney disease and elevated high-sensitivity C-reactive protein: A secondary analysis from the JUPITER (Justification for the Use of Statins in Prevention-an Intervention Trial Evaluating Rosuvastatin) trial. J Am Coll Cardiol 2010;55: 1266-1273.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1266-1273
    • Ridker, P.M.1    MacFadyen, J.2    Cressman, M.3    Glynn, R.J.4
  • 17
    • 33749534161 scopus 로고    scopus 로고
    • Telomeres and telomerase: The path from maize, Tetrahymena and yeast to human cancer and aging
    • DOI 10.1038/nm1006-1133, PII NM10061133
    • Blackburn EH, Greider CW, Szostak JW. Telomeres and telomerase: The path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med 2006;12: 1133-1138. (Pubitemid 44527346)
    • (2006) Nature Medicine , vol.12 , Issue.10 , pp. 1133-1138
    • Blackburn, E.H.1    Greider, C.W.2    Szostak, J.W.3
  • 22
    • 79960322707 scopus 로고    scopus 로고
    • The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
    • Bernardes de Jesus BB, Schneeberger K, Vera E, Tejera, A, Harley CB, Blasco MA. The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell 2011;10:604-621.
    • (2011) Aging Cell , vol.10 , pp. 604-621
    • Bernardes De Jesus, B.B.1    Schneeberger, K.2    Vera, E.3    Tejera, A.4    Harley, C.B.5    Blasco, M.A.6
  • 26
    • 74549184608 scopus 로고    scopus 로고
    • Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease
    • Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA 2010;303:250-257.
    • (2010) JAMA , vol.303 , pp. 250-257
    • Farzaneh-Far, R.1    Lin, J.2    Epel, E.S.3    Harris, W.S.4    Blackburn, E.H.5    Whooley, M.A.6
  • 28
    • 84866739365 scopus 로고    scopus 로고
    • A randomized controlled trial of qigong exercise on fatigue symptoms, functioning, and telomerase activity in persons with chronic fatigue or chronic fatigue syndrome
    • Ho RT, Chan JS, Wang CW, Lau BW, So KF, Yuen LP, Sham JS, Chan CL. A randomized controlled trial of qigong exercise on fatigue symptoms, functioning, and telomerase activity in persons with chronic fatigue or chronic fatigue syndrome. Ann Behav Med 2012;44:160-170.
    • (2012) Ann Behav Med , vol.44 , pp. 160-170
    • Ho, R.T.1    Chan, J.S.2    Wang, C.W.3    Lau, B.W.4    So, K.F.5    Yuen, L.P.6    Sham, J.S.7    Chan, C.L.8
  • 30
    • 84870892573 scopus 로고    scopus 로고
    • A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: Effects on mental health, cognition, and telomerase activity
    • Lavretsky H, Epel ES, Siddarth P, Nazarian N, Cyr NS, Khalsa DS, Lin J, Blackburn E, Irwin MR. A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: Effects on mental health, cognition, and telomerase activity. Int J Geriatr Psychiatry 2013;28: 57-65.
    • (2013) Int J Geriatr Psychiatry , vol.28 , pp. 57-65
    • Lavretsky, H.1    Epel, E.S.2    Siddarth, P.3    Nazarian, N.4    Cyr, N.S.5    Khalsa, D.S.6    Lin, J.7    Blackburn, E.8    Irwin, M.R.9
  • 31
    • 84867364065 scopus 로고    scopus 로고
    • How "reversible" is telomeric aging?
    • Epel E. How "reversible" is telomeric aging? Cancer Prev Res 2012;5:1163-1168.
    • (2012) Cancer Prev Res , vol.5 , pp. 1163-1168
    • Epel, E.1
  • 33
    • 84856285216 scopus 로고    scopus 로고
    • Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types
    • Yung LY, Lam WS, Ho MK, Hu Y, Ip FC, Pang H, Chin AC, Harley CB, Ip NY, Wong YH. Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types. Planta Medica 2012;78:115-121.
    • (2012) Planta Medica , vol.78 , pp. 115-121
    • Yung, L.Y.1    Lam, W.S.2    Ho, M.K.3    Hu, Y.4    Ip, F.C.5    Pang, H.6    Chin, A.C.7    Harley, C.B.8    Ip, N.Y.9    Wong, Y.H.10
  • 34
    • 78449260398 scopus 로고    scopus 로고
    • In vitro intestinal absorption and firstpass intestinal and hepatic metabolism of cycloastragenol, a potent small molecule telomerase activator
    • Zhu J, Lee S, Ho MK, Hu Y, Pang H, Ip FC, Chin AC, Harley CB, Ip NY, Wong YH. In vitro intestinal absorption and firstpass intestinal and hepatic metabolism of cycloastragenol, a potent small molecule telomerase activator. Drug Metab Pharmacokinet 2010;25:477-486.
    • (2010) Drug Metab Pharmacokinet , vol.25 , pp. 477-486
    • Zhu, J.1    Lee, S.2    Ho, M.K.3    Hu, Y.4    Pang, H.5    Ip, F.C.6    Chin, A.C.7    Harley, C.B.8    Ip, N.Y.9    Wong, Y.H.10
  • 35
    • 84874016802 scopus 로고    scopus 로고
    • Association between telomere length and experimentally induced upper respiratory viral infection in healthy adults
    • Cohen S, Janicki-Deverts D, Turner RB, Casselbrant ML, Li-Korotky HS, Epel ES, Doyle WJ. Association between telomere length and experimentally induced upper respiratory viral infection in healthy adults. JAMA 2013;309: 699-705.
    • (2013) JAMA , vol.309 , pp. 699-705
    • Cohen, S.1    Janicki-Deverts, D.2    Turner, R.B.3    Casselbrant, M.L.4    Li-Korotky, H.S.5    Epel, E.S.6    Doyle, W.J.7
  • 41
    • 0035099978 scopus 로고    scopus 로고
    • The inverse association between age and cholesterol level among older patients: The role of poor health status
    • DOI 10.1159/000052768
    • Volpato S, Zuliani G, Guralnik JM, Palmieri E, Fellin R. The inverse association between age and cholesterol level among older patients: The role of poor health status. Gerontology 2001;47:36-45. (Pubitemid 32215815)
    • (2001) Gerontology , vol.47 , Issue.1 , pp. 36-45
    • Volpato, S.1    Zuliani, G.2    Guralnik, J.M.3    Palmieri, E.4    Fellin, R.5
  • 42
    • 84858749132 scopus 로고    scopus 로고
    • Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials
    • Kelley GA, Kelley KS, Roberts S, Haskell W. Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: A meta-analysis of randomized controlled trials. Clin Nutr 2012;31:156-167.
    • (2012) Clin Nutr , vol.31 , pp. 156-167
    • Kelley, G.A.1    Kelley, K.S.2    Roberts, S.3    Haskell, W.4
  • 44
  • 46
    • 0036999173 scopus 로고    scopus 로고
    • Vitamins, homocysteine and cardiovascular risk
    • DOI 10.1023/A:1022126100625
    • Graham IM, O'Callaghan P. Vitamins, homocysteine and cardiovascular risk. Cardiovasc Drugs Ther 2002;16:383-389. (Pubitemid 36255738)
    • (2002) Cardiovascular Drugs and Therapy , vol.16 , Issue.5 , pp. 383-389
    • Graham, I.M.1    O'Callaghan, P.2
  • 48
    • 58149138834 scopus 로고    scopus 로고
    • Too much folate: A risk factor for cancer and cardiovascular disease?
    • Sauer J, Mason JB, Choi SW. Too much folate: A risk factor for cancer and cardiovascular disease? Curr Opin Clin Nutr Metabol Care 2009;12:30-36.
    • (2009) Curr Opin Clin Nutr Metabol Care , vol.12 , pp. 30-36
    • Sauer, J.1    Mason, J.B.2    Choi, S.W.3
  • 49
    • 0030763532 scopus 로고    scopus 로고
    • Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older
    • DOI 10.1056/NEJM199709043371003
    • Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 1997;337:670-676. (Pubitemid 27375473)
    • (1997) New England Journal of Medicine , vol.337 , Issue.10 , pp. 670-676
    • Dawson-Hughes, B.1    Harris, S.S.2    Krall, E.A.3    Dallal, G.E.4
  • 51
    • 79960322707 scopus 로고    scopus 로고
    • The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
    • Bernardes de Jesus B, Schneeberger K, Vera E, Tejera A, Harley CB, Blasco MA. The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell 2011;10:604-621.
    • (2011) Aging Cell , vol.10 , pp. 604-621
    • Bernardes De Jesus, B.1    Schneeberger, K.2    Vera, E.3    Tejera, A.4    Harley, C.B.5    Blasco, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.