Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer

Carcinogenesis

Volumn 29, Issue 4, 2008, Pages 747-753

  Perera, Samanthi A ^a   Maser, Richard S ^a   Xia, Huili ^a   McNamara, Kate ^a   Protopopov, Alexei ^a   Chen, Liang ^a   F hezel, Aram ^a   Kim, Carla F ^b   Bronson, Roderick T ^b   Castrillon, Diego H ^c   Chin, Lynda ^a   Bardeesy, Nabeel ^d   DePinho, Ronald A ^a,b   Wong, Kwok Kin ^a,e  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

K RAS PROTEIN; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER MODEL; CHROMOSOME ABERRATION; CONTROLLED STUDY; GENE MUTATION; GENETIC MODEL; GENOMIC INSTABILITY; HETEROZYGOSITY; HISTOPATHOLOGY; LIFESPAN; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; LUNG CARCINOGENESIS; METASTASIS POTENTIAL; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TELOMERE;

ANIMALS; DISEASE MODELS, ANIMAL; GENES, RAS; GENOMIC INSTABILITY; LUNG NEOPLASMS; MICE; MICE, TRANSGENIC; MUTATION; NEOPLASM METASTASIS; TELOMERE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 41849143017     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn050     Document Type: Article

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