Feeding animals with GM crops: Boon or bane?

Indian Journal of Biotechnology

Volumn 12, Issue 3, 2013, Pages 311-322

  Deb, Rajib ^a   Sajjanar, Basavraj ^b   Devi, Karuna ^c   Reddy, K M ^d   Prasad, Rajendra ^a   Kumar, Sushil ^a   Sharma, Arjava ^a  

^a Project Directorate on Cattle   (India)

^b ICAR NATIONAL INSTITUTE OF ABIOTIC STRESS MANAGEMENT   (India)

^c INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^d National Academy of Agricultural Research Management India   (India)

Author keywords

Genetically modified (GM) crops; Livestock; Safety assessment

Indexed keywords

ANIMAL FOOD; ARTICLE; CROP; DIGESTION; ECONOMIC ASPECT; FARM ANIMAL; FEEDING; FISHERY; FOOD COMPOSITION; FOOD SAFETY; GENETICALLY MODIFIED FOOD; HEALTH HAZARD; LIVESTOCK; NONHUMAN; NUTRITIONAL ASSESSMENT; POULTRY; RISK ASSESSMENT;

EID: 84886004149     PISSN: 09725849     EISSN: 09750967     Source Type: Journal    
DOI: None     Document Type: Article

References (94)

1. Delgado C, Rosegrant M, Steinfeld H, Ehui S&Courbois C,. Livestock to 2020: The next food revolution, Food, Agriculture and the Environment Discussion Paper 28 (International Food Policy Research Institute, Washington, DC; Food and Agriculture Organization, Rome, Italy&International Livestock Research Institute, Nairobi, Kenya) 1999.
2. Rosegrant M W, Paisner M S, Meijer S&Witcover J,. 2020 global food outlook: Trends, alternatives, and choices (International Food Policy Research Institute, Washington, DC, USA) 2001-2020.
3. Brown L R,. The United States and China, the soybean connection, Press notice 9 November 1999 (World Watch Institute, Washington, DC, USA) 1999.
4. Annual Dairy Report (2001-2002) (University of Nebraska, Lincoln, USA).
5. Agnihotri A&Kaushik N,. Transgressive segregation and selection of erucic acid strain from intergeneric crosses of Brassica, Indian J Plant Genet Resour, 11 (1998) 251-255.
6. th Pacific Rim Conf on 'Biotechnology of Bacillus thuringiensis and its environmental impact' (Australian National University, Canberra, Australia) 2001, 246-253. [Abstract S 6.1]
7. Pailan G H&Singhal K K,. Effect of dietary glucosinolates on nutrient utilization, milk yield and blood constituents of lactating goats, Small Ruminants Res, 71 (1997) 31-37.
8. Papas A, Ingalls J R&Campbell L D,. Studies on the effects of rapeseed meal on thyroid status of cattle, glucosinolate and iodine content of milk and other parameters, J Nutr, 109 (1979) 1129-1139.
9. James C,. Global review of commercialized transgenic crops: 1999. ISAAA Brief No.12: Preview (International Service for the Acquisition of Agri-Biotech Applications, Ithaca, NY, USA) 1999.
10. The World of Corn, US corn consumption-Livestock (National Corn Growers Association) 2000. [http://www.ncga.com/03world/main/corn_consumption_livestock.html]
11. Phipps R H,. Safety of food products derived from livestock receiving GM feed ingredients, paper presented at International Conference on Food and Feed Safety, Doha, Qatar, held on September, 2002.
12. Bell J M,. Nutrients and toxicants in rapeseed meal-A review, J Anim Sci, 58 (1984) 996-1010.
13. Nordlee J A, Taylor S L, Townsend J A, Thomas L A&Bush R K,. Identification of a Brazil-nut allergen in transgenic soybeans, N Engl J Med, 334 (1996) 688-692.
14. Ewen SW&Pusztai A,. Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine, Lancet, 354 (1999) 1353-1354.
15. Piva G, Morlacchini M, Pietri A, Rossi F&Prandini A,. Growth performance of broilers fed insect-protected (MON810) or near isogenic control corn, J Poult Sci, 80 Suppl 1 (2001) 320. [Abstr 1324]
16. de Vendômois J S, Roullier F, Cellier D&Seralini G-E,. A comparison of the effects of three GM corn varieties on mammalian health, Int J Biol Sci, 5 (2009) 706-726.
17. Steinfeld H, Gerber P, Wassenaar T, Castel V, Rosales M et al,. Livestock's long shadow: Environmental issues and options (FAO, Rome) 2006, p 406.
18. Losey J E, Rayor L S&Carter M E,. Transgenic pollen harms monarch larvae, Nature (Lond), 399 (1999) 214.
19. Pirondini A&Marmiroli N, Environmental risk assessment in GMO analysis, Riv Biol, 103 (2010) 371-402.
20. Guzin C G, Gameze A&Remziye Y,. Qualitative detection of GM maize (Bt 11) in food and feed sold commercially in Turkey by PCR based methods, Indian J Biotechnol, 10 (2011) 143-146.
21. ILSI,. Best practices for the conduct of animal studies to evaluate crops genetically modified for output traits (International Life Science Institute, Washington DC, USA) 2007
22. Novak W K&Haslberger A G,. Substantial equivalence of antinutrients and inherent plant toxins in genetically modified novel foods, Food Chem Toxicol, 38 (2000) 473-483.
23. OECD,. Safety evaluation of foods derived from modern biotechnology-Concepts and principles (Organization for Economic Cooperation and Development, Paris, France) 1993.
24. OECD,. Biotechnology regulatory contacts in OECD member countries (Organization for Economic Cooperation and Development, Paris, France) 1996.
25. OECD,. Biotechnology regulatory contacts in OECD member countries (Organization for Economic Cooperation and Development, Paris, France) 1998.
26. Aumaitre A, Aulrich K, Chesson A, Flachowsky G&Piva G,. New feeds from genetically modified plants: Substantial equivalence, digestibility, and safety for animals and the food chain, Livest Prod Sci, 74 (2002) 223-238.
27. Kuiper H A, Kleter G A, Noteborn H P&Kok E J,. Assessment of the food safety issues related to genetically modified foods, Plant J, 27 (2001) 503-528.
28. Faust M A,. Livestock products: Corn composition and detection of transgenic DNA/proteins, paper presented in Symposium held in conjunction with American Dairy Science Association and American Society of Animal Science Meeting, Baltimore, USA, July 2000.
29. Flachowsky G&Aulrich K,. Nutritional assessment of feeds from genetically modified organism, J Anim Feed Sci, 10 (2001) 181-194.
30. WHO,. Principles of the safety assessment of food additives and contaminants in food-Environmental health criteria no. 70 (World Health Organisation, Geneva, Switzerland) 1993.
31. Beever D E&Kemp C F,. Safety issues associated with the DNA in animal feed derived from genetically modified crops: A review of scientific and regulatory procedures, Nutr Abstr Rev, Sers B, 70 (2000) 175-182.
32. Beever D E&Phipps R H,. The fate of plant DNA and novel proteins in feeds for farm livestock: A United Kingdom perspective, J Anim Sci, 79 (2001) E290-E295.
33. Clark J H&Ipharranguerre I R,. Livestock performance: Feeding biotech crops, J Dairy Sci, 84 (2001) E9-E18.
34. Clark J H&Bateman H G II,. Use and future prospects of soy products in dairy cattle diets, in Opportunities for soy products in animal nutrition, edited by J K Drackley (Federation of Animal Science Societies, Savoy, IL, USA) 1999, 87-105.
35. Gold M,. The global benefit of eating less meat (Compassion in World Farming Trust) 2004.[www.ciwf.org.uk/includes/./global_benefits_of_eating_less_meat.pdf]
36. Singhal K K,. Oil seed cake for live stock feeding, Publ no. 220 (National Dairy Research Institute, Karnal, India) 1986.
37. Singh M, Tiwari D P, Kumar A,. Effects of feeding transgenic cottonseed on nutrients utilization, milk production and its composition in lactating Murrah buffaloes, Buffalo J, 19 (2003) 117-126.
38. Castillo A R, Gallardo M R, Maciel M, Giordano J M, Conti G A et al,. Effects of feeding rations with genetically modified whole cottonseed to lactating dairy cows, J Dairy Sci, 87 (2004) 1778-1785.
39. Folmer J., Grant R J, Milton C T&Beck J,. Utilization of Bt corn residues by grazing beef steers and Bt corn silage and grain by growing beef cattle and lactating dairy cows, J Anim Sci, 80 (2002) 1352-1361.
40. Bohme H, Aulrich K, Daenicke R&Flachowsky G,. Genetically modified feeds in animal nutrition. 2nd communication: Glufosinate tolerant sugar beets (roots and silage) and maize grains for ruminants and pigs, Arch Tierernahr, 54 (2001) 197-207.
41. Donkin S S, Velez J C, Totten A K, Stanisiewski E P&Hartnell G F,. Effects of feeding silage and grain from glyphosate-tolerant or insect-protected corn hybrids on feed intake, ruminal digestion, and milk production in dairy cattle, J Dairy Sci, 86 (2003) 1780-1788.
42. Grant R J, Fanning K C, Kleinschmit D, Stanisiewski E P&Hartnell G F,. Influence of glyphosate-tolerant (event nk603) and corn rootworm protected (event MON863) corn silage and grain on feed consumption and milk production in Holstein cattle, J Dairy Sci, 86 (2003) 1707-1715.
43. Chowdhury E H, Mikami O, Murata H, Sultana P, Shimada N et al,. Fate of maize intrinsic and recombinant genes in calves fed genetically modified maize Bt11, J Food Prot, 67 (2004) 365-370.
44. Einspanier R, Lutz B, Rief S, Berezina O, Zverlov V et al,. Tracing residual recombinant feed molecules during digestion and rumen bacterial diversity in cattle fed transgene maize, Eur Food Res Technol, 218 (2004) 269-273.
45. Hamilton K A, Pyla P D, Breeze M, Olson T, Li M H et al,. Bollgard II cotton: Compositional analysis and feeding studies of cottonseed from insect-protected cotton (Gossypium hirsutum L.) producing the Cry1Ac and Cry2Ab2 proteins, J Agric Food Chem, 52 (2004) 6969-6976.
46. Russell J, Farnham D, Berryman R K, Hersom M J, Pugh A et al,. Nutritive value of the crop residues from bt-corn hybrids and their effects on performance of grazing beef cows, Beef Res Rep-Iowa State Univ, A S Leaflet R1723 (2000) 56-61.
47. Onkin S S, Velez J C, Totten A K, Stanisiewski E P&Hartnell G F,. Effects of feeding silage and grain from glyphosate-tolerant or insect-protected corn hybrids on feed intake, ruminal digestion, and milk composition in dairy cattle, J Dairy Sci, 86 (2003) 1780-1788.
48. Folmer J D, Grant R J, Milton C T&Beck J,. Utilization of Bt corn residues by grazing beef steers and Bt corn silage and grain by growing beef cattle and lactating dairy cows, J Anim Sci, 80 (2002) 1352-1361.
49. Munkvold G P, Hellmich R L&Rice L G,. Comparison of fumonisin concentrations in kernels of transgenic Bt maize hybrids and nontransgenic hybrids, Plant Dis, 83 (1999) 130-138.
50. Munkvold G P, Hellmich R L&Showers W B,. Reduced Fusarium ear rot and symptom less infection in kernels of maize genetically engineered for European corn borer resistance, Phytopathology, 87 (1997) 1071-1077.
51. Calsamiglia S, Hernandez B, Hartnell G F&Phipps R,. Effects of corn silage derived from a genetically modified variety containing two transgenes on feed intake, milk production, and composition, and the absence of detectable transgenic deoxyribonucleic acid in milk in Holstein dairy cows, J Dairy Sci, 90 (2007) 4718-4723.
52. Phipps R H, Jones A K, Tingey A P&Abeyasekera S,. Effect of corn silage from an herbicide-tolerant genetically modified variety on milk production and absence of transgenic DNA in milk, J Dairy Sci, 88 (2005) 2870-2878.
53. Padgette S R, Taylor N B, Nida D I, Bailey M R, MacDonald J et al,. The composition of glyphosate-tolerant soybean seed is equivalent to that of conventional soybeans, J Nutr, 126 (1996) 702-716.
54. Sidhu R S, Hammond B G, Fuchs R L, Mutz J, Holden L R et al,. Glyphosate-tolerant corn: The composition and feeding value of grain from glyphosate-tolerant corn is equivalent to that of conventional corn (Zea mays L.), J Agric Food Chem, 48 (2000) 2305-2312.
55. Singh M, Tiwari D P, Kumar A and Kumar M R,. Effect of feeding transgenic cottonseed vis-à-vis non-transgenic cottonseed on haematobiochemical constituents in lactating Murrah buffaloes, Asian-Australasian J Anim Sci, 16 (2003) 1732-1737.
56. Combs D K&Hartnell G F,. Alfalfa containing the glyphosate-tolerant trait has no effect on feed intake, milk composition, or milk production of dairy cattle, J Dairy Sci, 91 (2008) 673-678.
57. Mohanta R K, Singhal K K, Tyagi A K, Rajput Y S&Prasad S,. Nutritional evaluation of transgenic cottonseed in the ration of lactating dairy cows, Trop Anim Health Prod, 42 (2010) 431-438.
58. Lutz B, Wiedemann S, Einspanier R, Mayer J&Albrecht C,. Degradation of Cry1Ab protein from genetically modified maize in the bovine gastrointestinal tract, J Agric Food Chem, 53 (2005) 1453-1456.
59. Reuter T&Aulrich K,. Investigations on genetically modified maize (Bt-maize) in pig nutrition: Fate of feedingested foreign DNA in pig bodies, Eur Food Res Technol, 216 (2003) 185-192.
60. Jennings J C, Kolwyck D C, Kays S B, Whetsell A J, Surber J B et al,. Determining whether transgenic and endogenous plant DNA and transgenic protein are detectable in muscle from swine fed Roundup Ready soybean meal, J Anim Sci, 81 (2003) 1447-1455.
61. Hyun Y, Bressner G E, Ellis M, Lewis A J, Fischer R et al,. Performance of growing-finishing pigs fed diets containing Roundup Ready corn (event nk603), a nontransgenic genetically similar corn, or conventional corn lines, J Anim Sci, 82 (2004) 571-580.
62. Broll H, Zagon J, Butschke A, Leffke A, Spiegelberg A et al,. The fate of DNA of transgenic inulin synthesizing potatoes in pigs, J Anim Feed Sci, 14 (2005) 337-340.
63. Barriere Y, Verite R, Brunschwig P, Surault F&Emile J C,. Feeding value of corn silage estimated with sheep and dairy cows is not altered by genetic incorporation of Bt1376 resistance to Ostrinia nubilalis, J Dairy Sci, 84 (2001) 1863-1871.
64. Alexander T W, Reuter T, Okine E, Sharma R&Mc Allister T A,. Conventional and real-time polymerase chain reaction assessment of the fate of transgenic DNA in sheep fed Roundup Ready rapeseed meal, Br J Nutr, 96 (2006) 997-1005.
65. Cromwell G L, Lindemann M D, Randolph J H, Parker G R, Coffey R D et al,. Soybean meal from Roundup Ready or conventional soybeans in diets for growing-finishing swine J Anim Sci, 80 (2002) 708-715.
66. Qiu X, Apgar G A, Griswold K E, Beagle J M, Martin M P et al,. Digestive fate of a gdhA gene from a genetically modified corn fed to growing pigs, J Anim Sci, 82 Suppl 1 (2004) 329. [Abstr W66]
67. Reuter T, Aulrich K&Berk A,. Investigations on genetically modified maize (Bt-maize) in pig nutrition: Fattening performance and slaughtering results, Arch Tierernahr, 56 (2002) 319-326.
68. Sissener N H, Sanden M, Bakke A M, Krogdahl Å&Hemre G-I,. A long term trial with Atlantic Salmon (Salmo salar L.) fed genetically modified soy; focusing general health and performance before, during and after the parr-smolt transformation, Aquaculture, 294 (2009) 108-117.
69. Vander Pol K J, Erickson G E, Robbins N D, Berger L L, Wilson C B et al,. Effects of grazing residues or feeding corn from a corn rootworm-protected hybrid (MON 863) compared with reference hybrids on animal performance and carcass characteristics, J Anim Sci, 83 (2005) 2826-2834.
70. Peterson B A, Hyun Y, Stanisiewski E P, Hartnell G F&Ellis M,. Performance of growing-finishing pigs fed diets containing Roundup Ready wheat (MON 71800), a nontransgenic genetically similar wheat, or conventional wheat varieties, Animal, 2 (2008) 1602-1609.
71. Rizzi A, Brusetti L, Arioli S, Nielsen K M, Tamagnini I et al,. Detection of feed-derived maize DNA in goat milk and evaluation of the potential of horizontal transfer to bacteria, Eur Food Res Technol, 227 (2008) 1699-1709.
72. Thomas B R&Bradford K J, Crop biotechnology: Feeds for livestock (Seed Biotechnology Centre, University of California, Davis, USA) 2001. [http://sbc.ucdavis.edu/outreach/abc/livestock_feeds_abc.htm.]
73. Hartnell G F, Hvelplund T&Weisbjerg M R,. Nutrient digestibility in sheep fed diets containing Roundup Ready or conventional fodder beet, sugar beet, and beet pulp, J Anim Sci, 83 (2005) 400-407.
74. Anilkumar B, Reddy A G, Kalakumar B, Rani M U, Anjaneyulu Y et al,. Sero-biochemical studies in sheep fed with Bt cotton plants, Toxicol Int, 17 (2010) 99-101.
75. Tripathi M K, Mondal D, Somvanshi R&Karim S A,. Haematology, blood biochemistry and tissue histopathology of lambs maintained on diets containing an insect controlling protein (Cry1Ac) in Bt-cotton seed, J Anim Physiol Anim Nutr (Berl), 95 (2011) 545-555.
76. Tudisco R, Lombardi P, Bovera F, d'Angelo D, Cutrignelli M I et al,. Genetically modified soya bean in rabbit feeding: Detection of DNA fragments and evaluation of metabolic effects by enzymatic analysis, Anim Sci, 82 (2006) 193-199.
77. Chesson A&Flachowsky G,. Transgenic plants in poultry nutrition, World Poult Sci J, 59 (2003) 201-208.
78. Aeschbacher K, Messikommer R, Meile L&Wenk C,. Bt176 corn in poultry nutrition: Physiological characteristics and fate of recombinant plant DNA in chickens, Poult Sci, 84 (2005) 385-394.
79. Scheideler S E, Hileman R E, Weber T, Robeson L&Hartnell G F,. The in vivo digestive fate of the Cry3Bb1 protein in laying hens fed diets containing MON 863 corn, Poult Sci, 87 (2008) 1089-1097.
80. Mejia L, Jacobs C M, Utterback P L, Parsons C M, Rice D et al,. Evaluation of the nutritional equivalency of soybean meal with the genetically modified trait DP-3O5423-1 when fed to laying hens, Poult Sci, 89 (2010) 2634-2639.
81. Jacobs C M, Utterback P L, Parsons C M, Smith B, Hinds M et al,. Feeding performance in laying hens fed diets containing DAS-59122-7 maize grain compared with diets containing non-transgenic maize grain, Poult Sci, 87 (2008) 475-479.
82. Hammond B G, Vicini J L, Hartnell G F, Naylor M W, Knight C D et al,. The feeding value of soybeans fed to rats, chickens, catfish and dairy cattle is not altered by genetic incorporation of glyphosate tolerance, J Nutr, 126 (1996) 717-727.
83. Sauvé A&Brake J T,. Safety evaluation of event 5307 transgenic corn in broiler chickens, Poult Sci, 89 E-Suppl 1 (2010) 96. [Abstr M245]
84. Scholtz N, Flachowsky G, Halle I&Sauerwein H,. Metabolic and histological evaluation of quails with or without genetically modified Bt-maize, J Anim Sci, 87 E-Suppl 2 (2009) 390. [Abstr W19]
85. Flachowsky G, Halle I&Aulrich K,. Long term feeding of Bt-corn-A ten-generation study with quails, Arch Anim Nutr, 59 (2005) 449-451.
86. Halver J E&Hardy R W,. Fish nutrition, 3rd edn (Academic Press, California, USA) 2002, pp 824.
87. Brown P B, Wilson K A, Jonker Y&Nickson T E, Glyphosate tolerant canola meal is equivalent to the parental line in diets fed to rainbow trout, J Agric Food Chem, 51 (2003) 4268-4272.
88. Sanden M, Berntssen M H, Krogdahl A, Herme G I&Mc Kellep A M,. An examination of the intestinal tract of Atlantic salmon, Salmo salar L., parr fed different varieties of soy and maize, J Fish Dis, 28 (2005) 317-330.
89. Li M H, Hartnell G F, Robinson E H, Kronenberg J M, Healy C E et al,. Evaluation of cottonseed meal derived from genetically modified cotton as feed ingredients for channel catfish, Ictalurus punctatus, Aquacult Nutr, 14 (2008) 490-498.
90. Chainark P, Satoh S, Hirono S I, Aoki T&Endo M,. Availability of genetically modified feed ingredient: Investigations of ingested foreign DNA in rainbow trout Oncorhynchus mykiss, Fish Sci, 74 (2008) 380-390.
91. Glencross B J, Curnow W, Hawkins G W, Kissil M&Peterson D,. Evaluation of the feed value of a transgenic strain of the narrow-leaf lupin (Lupinus angustifolius) in the diet of the marine fish, Pagrus auratus, Aquacult Nutr, 9 (2003) 197-206.
92. Bakke-McKellep A M, Koppang C O, Gunnes G, Sanden M, Hemre G I et al,. Histological, digestive, metabolic, hormonal and some immune factor responses in Atlantic salmon, Salmo salar L., fed genetically modified soybeans, J Fish Dis, 30 (2007) 65-79.
93. Sanden M, Bruce I J, Rahman M A&Hemre G-I,. The fate of transgenic sequences present in genetically modified plant products in fish feed, investigating the survival of GM soybean DNA fragments during feeding trials in Atlantic salmon, Salmo salar L., Aquaculture, 237 (2004) 391-405.
94. Frøystad-Saugen M K, Lilleeng E, Bakke-McKellep A M, Vekterud K, Valen E C et al,. Distal intestinal gene expression in Atlantic salmon (Salmo salar L.) fed genetically modified maize, Aquacult Nutr, 15 (2009) 104-115.