Determining whether transgenic and endogenous plant DNA and transgenic protein are detectable in muscle from swine fed Roundup Ready soybean meal

Journal of Animal Science

Volumn 81, Issue 6, 2003, Pages 1447-1455

  Jennings, J C ^a,c   Kolwyck, D C ^a   Kays, S B ^a   Whetsell, A J ^a   Surber, J B ^a   Cromwell, G L ^b   Lirette, R P ^a   Glenn, K C ^a  

^a MONSANTO COMPANY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c Mail Stop BB5B ^*  (United Kingdom)

Author keywords

Biotechnology; Enzyme linked immunosorbent assay; Pigs; Polymerase chain reaction; Soybeans

Indexed keywords

AGROBACTERIUM; AGROBACTERIUM SP.; ANIMALIA; GLYCINE MAX; RHIZOBIUM; SUIDAE; SUS SCROFA;

PLANT DNA; VEGETABLE PROTEIN;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETICS; GROWTH, DEVELOPMENT AND AGING; MALE; METABOLISM; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SOUTHERN BLOTTING; SOYBEAN; SWINE; TRANSGENIC PLANT;

ANIMAL FEED; ANIMALS; BASE SEQUENCE; BLOTTING, SOUTHERN; DNA, PLANT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; MALE; MUSCLE, SKELETAL; PLANT PROTEINS; PLANTS, GENETICALLY MODIFIED; POLYMERASE CHAIN REACTION; SOYBEANS; SWINE;

EID: 0642337850     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/2003.8161447x     Document Type: Article

References (20)

1. Arumuganathan, K., and E. D. Earle. 1991. Nuclear DNA content of some important plant species. Plant Mol. Biol. Reporter 9:208-218.
2. Ash, J. A., E. Scheideler, and C. L. Novak. 2000. The fate of genetically modified protein from Roundup Ready® soybeans in the laying hen. Poult. Sci. 79(Suppl. 1):26. (Abstr.)
3. Beever, D. E., and C. F. Kemp. 2000. Safety issues associated with the DNA in animal feed derived from genetically modified crops. A review of scientific and regulatory procedures. Nutr. Abstr. Rev., Ser. B: Livest. Feeds Feeding 70:175-182.
4. Cromwell, G. L., M. D. Lindemann, J. H. Randolph, G. R. Parker, R. D. Coffey, K. M. Laurent, C. L. Armstrong, W. B. Mikel, E. P. Stanisiewski, and G. F. Hartnell. 2002. Soybean meal from Roundup Ready or conventional soybeans in diets for growing-finishing swine. J. Anim. Sci. 80:708-715.
5. FAO/WHO. 1991. Strategies for Assessing the Safety of Foods Processed by Biotechnology. Report of a joint FAO/WHO consultation. WHO, Geneva, Switzerland.
6. FAO/WHO. 1996. Biotechnology and Food Safety. Report of a joint FAO/WHO consultation. FAO, Food and Nutr. Paper 61. WHO, Geneva, Switzerland.
7. Faust, M. A. 2002. New feeds from genetically modified plants: The U.S. approach to safety for animals and the food chain. Livest. Prod. Sci. 74:239-254.
8. Flachowsky, G., and K. Aulrich. 2001. The use of genetically modified organisms (GMOs) in animal nutrition. Surveys Anim. Nutr. 29:45-79.
9. Harrison, L. A., M. R. Bailey, M. W. Naylor, J. E. Ream, B. G. Hammond, D. L. Nida, B. L. Burnette, T. E. Nickson, T. A. Mitsky, M. L. Taylor, R. L. Fuchs, and S. R. Padgette. 1996. The expressed protein in glyphosate-tolerant soybean, 5-enolpyruvylshikimate-3 phosphate synthase from Agrobacterium sp. strain CP4, is rapidly digested in vitro and is not toxic to acutely gavaged mice. J. Nutr. 126:728-740.
10. Jennings, J. C., L. D. Albee, D. C. Kolwyck, J. B. Surber, M. L. Taylor, G. F. Hartnell, R. P. Lirette, and K. C. Glenn. 2003. Attempts to detect transgenic and endogenous plant DNA and transgenic protein in muscle from broilers fed YieldGard Corn Borer corn. Poult. Sci. 82:371-380.
11. Jonas, D. A., I. Elmadfa, K.-H. Engel, K. J. Heller, G. Kozianowski, A. König, D. Müller, J. F. Narbonne, W. Wackernagel, and J. Kleiner. 2001. Safety considerations of DNA in food. Ann. Nutr. Metab. 45:235-254.
12. Khumnirdpetch, V., U. Intarachote, S. Treemanee, S. Tragoonroong, and S. Thummabood. 2001. Detection of GMOs in the broilers that utilized genetically modified soybeanmeals as a feed ingredient. Plant Anim. Genome IX Conf., San Diego, CA. (Abstr. 585).
13. Klotz, A., and R. Einspanier. 1998. Detection of "novel-feed" in animals? Injury of consumers of meat or milk is not expected. Mais 3:109-111.
14. Lipp, M., E. Anklam, and J. W. Stave. 2000. Validation of an immunoasssay for detection and quantitation of a genetically modified soybean in food and food fractions using reference materials: Interlaboratory study. J. AOAC Int. 83:919-927.
15. Metcalfe, D. D., J. D. Astwood, R. Townsend, H. A. Sampson, S. L. Taylor, and R. L. Fuchs. 1996. Assessment of the allergenic potential of foods derived from genetically engineered crop plants. Crit. Rev. Food Sci. Nutr. 36:165-186.
16. NRC. 1994. Nutritional Requirements of Poultry. 9th ed. Natl. Acad. Press, Washington, DC.
17. NRC. 1998. Nutritional Requirements of Swine. 10th ed. Natl. Acad. Press, Washington, DC.
18. OECD. 1998. Report of the OECD Workshop on the Toxicological and Nutritional Testing of Novel Foods. Paris, France.
19. OECD. 2000. Report of the OECD Task Force for the Safety of Novel Foods and Feeds. Okinawa, Japan.
20. Phipps, R. H., D. E. Beever, and D. J. Humphries. 2002. Detection of transgenic DNA in milk from cows receiving herbicide tolerant (CP4EPSPS) soyabean meal. Livest. Prod. Sci. 74:269-273.