메뉴 건너뛰기




Volumn 54, Issue 11, 2013, Pages 2964-2978

10E,12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species

Author keywords

Carnitine palmitoyl transferase I; Etomoxir; Glucose uptake; Inflammation; Lipid metabolism

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE I; CARNITINE PALMITOYLTRANSFERASE IALPHA; CONJUGATED LINOLEIC ACID; REACTIVE OXYGEN METABOLITE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84885992782     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M035188     Document Type: Article
Times cited : (46)

References (76)
  • 1
    • 0037048640 scopus 로고    scopus 로고
    • Trends and correlates of class 3 obesity in the United States from 1990 through 2000
    • Freedman, D. S., L. K. Khan, M. K. Serdula, D. A. Galuska, and W. H. Dietz. 2002. Trends and correlates of class 3 obesity in the United States from 1990 through 2000. JAMA. 288: 1758-1761.
    • (2002) JAMA , vol.288 , pp. 1758-1761
    • Freedman, D.S.1    Khan, L.K.2    Serdula, M.K.3    Galuska, D.A.4    Dietz, W.H.5
  • 2
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2000
    • Flegal, K. M., M. D. Carroll, C. L. Ogden, and C. L. Johnson. 2002. Prevalence and trends in obesity among US adults, 1999-2000. JAMA. 288: 1723-1727.
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Johnson, C.L.4
  • 3
    • 57749093663 scopus 로고    scopus 로고
    • "Sick fat," metabolic disease, and atherosclerosis
    • Bays, H. E. 2009. "Sick fat," metabolic disease, and atherosclerosis. Am. J. Med. 122: S26-S37.
    • (2009) Am. J. Med. , vol.122
    • Bays, H.E.1
  • 7
    • 13644271674 scopus 로고    scopus 로고
    • Impaired lipid accumulation by trans10, cis12 CLA during adipocyte differentiation is dependent on timing and length of treatment
    • DOI 10.1016/j.bbalip.2004.08.018
    • Granlund, L., J. I. Pedersen, and H. I. Nebb. 2005. Impaired lipid accumulation by trans10, cis12 CLA during adipocyte differentiation is dependent on timing and length of treatment. Biochim. Biophys. Acta. 1687: 11-22. (Pubitemid 40233020)
    • (2005) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1687 , Issue.1-3 , pp. 11-22
    • Granlund, L.1    Pedersen, J.I.2    Nebb, H.I.3
  • 10
    • 34047257009 scopus 로고    scopus 로고
    • Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese
    • DOI 10.1017/S0007114507381324, PII S0007114507381324
    • Gaullier, J. M., J. Halse, H. O. Høivik, K. Høye, C. Syvertsen, M. Nurminiemi, C. Hassfeld, A. Einerhand, M. O'Shea, and O. Gudmundsen. 2007. Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese. Br. J. Nutr. 97: 550-560. (Pubitemid 46662046)
    • (2007) British Journal of Nutrition , vol.97 , Issue.3 , pp. 550-560
    • Gaullier, J.-M.1    Halse, J.2    Hoivik, H.O.3    Syvertsen, C.4    Nurminiemi, M.5    Hassfeld, C.6    Einerhand, A.7    O'Shea, M.8    Gudmundsen, O.9
  • 11
    • 0034858073 scopus 로고    scopus 로고
    • Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue
    • Brown, J. M., Y. D. Halvorsen, Y. R. Lea-Currie, C. Geigerman, and M. McIntosh. 2001. Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue. J. Nutr. 131: 2316-2321. (Pubitemid 32851875)
    • (2001) Journal of Nutrition , vol.131 , Issue.9 , pp. 2316-2321
    • Brown, J.M.1    Halvorsen, Y.D.2    Lea-Currie, Y.R.3    Geigerman, C.4    McIntosh, M.5
  • 12
    • 0035661902 scopus 로고    scopus 로고
    • Trans-10,Cis-12 conjugated linoleic acid reduces triglyceride content while differentially affecting peroxisome proliferator activated receptor γ2 and ap2 expression in 3T3-L1 preadipocytes
    • Evans, M., Y. Park, M. Pariza, L. Curtis, B. Kuebler, and M. McIntosh. 2001. Trans-10,cis-12 conjugated linoleic acid reduces triglyceride content while differentially affecting peroxisome proliferator activated receptor gamma2 and aP2 expression in 3T3-L1 preadipocytes. Lipids. 36: 1223-1232. (Pubitemid 34007976)
    • (2001) Lipids , vol.36 , Issue.11 , pp. 1223-1232
    • Evans, M.1    Park, Y.2    Pariza, M.3    Curtis, L.4    Kuebler, B.5    McIntosh, M.6
  • 13
    • 33748291462 scopus 로고    scopus 로고
    • Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue
    • DOI 10.2337/db06-0036
    • Poirier, H., J. S. Shapiro, R. J. Kim, and M. A. Lazar. 2006. Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue. Diabetes. 55: 1634-1641. (Pubitemid 44324115)
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1634-1641
    • Poirier, H.1    Shapiro, J.S.2    Kim, R.J.3    Lazar, M.A.4
  • 16
    • 0036730666 scopus 로고    scopus 로고
    • Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome
    • DOI 10.2337/diacare.25.9.1516
    • Risérus, U., P. Arner, K. Brismar, and B. Vessby. 2002. Treatment with dietary trans10,cis12 conjugated linoleic acid causes isomerspecifi c insulin resistance in obese men with the metabolic syndrome. Diabetes Care. 25: 1516-1521. (Pubitemid 41071104)
    • (2002) Diabetes Care , vol.25 , Issue.9 , pp. 1516-1521
    • Riserus, U.1    Arner, P.2    Brismar, K.3    Vessby, B.4
  • 17
    • 5144228885 scopus 로고    scopus 로고
    • Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus
    • Moloney, F., T. Yeow, A. Mullen, J. Nolan, and H. Roche. 2004. Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am. J. Clin. Nutr. 80: 887-895. (Pubitemid 41202087)
    • (2004) American Journal of Clinical Nutrition , vol.80 , Issue.4 , pp. 887-895
    • Moloney, F.1    Yeow, T.-P.2    Mullen, A.3    Nolan, J.J.4    Roche, H.M.5
  • 19
    • 77955844665 scopus 로고    scopus 로고
    • Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis
    • Ashwell, M. S., R. P. Ceddia, R. L. House, J. P. Cassady, E. J. Eisen, T. E. Eling, J. B. Collins, S. F. Grissom, and J. Odle. 2010. Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis. J. Nutr. Biochem. 21: 848-855.
    • (2010) J. Nutr. Biochem. , vol.21 , pp. 848-855
    • Ashwell, M.S.1    Ceddia, R.P.2    House, R.L.3    Cassady, J.P.4    Eisen, E.J.5    Eling, T.E.6    Collins, J.B.7    Grissom, S.F.8    Odle, J.9
  • 20
    • 52149083045 scopus 로고    scopus 로고
    • Conjugated linoleic acid isomers have no effect on atherosclerosis and adverse effects on lipoprotein and liver lipid metabolism in apoE-/- mice fed a high-cholesterol diet
    • Cooper, M. H., J. R. Miller, P. L. Mitchell, D. L. Currie, and R. S. McLeod. 2008. Conjugated linoleic acid isomers have no effect on atherosclerosis and adverse effects on lipoprotein and liver lipid metabolism in apoE-/- mice fed a high-cholesterol diet. Atherosclerosis. 200: 294-302.
    • (2008) Atherosclerosis , vol.200 , pp. 294-302
    • Cooper, M.H.1    Miller, J.R.2    Mitchell, P.L.3    Currie, D.L.4    McLeod, R.S.5
  • 21
    • 49449090273 scopus 로고    scopus 로고
    • An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women
    • Tholstrup, T., M. Raff, E. M. Straarup, P. Lund, S. Basu, and J. M. Bruun. 2008. An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women. J. Nutr. 138: 1445-1451.
    • (2008) J. Nutr. , vol.138 , pp. 1445-1451
    • Tholstrup, T.1    Raff, M.2    Straarup, E.M.3    Lund, P.4    Basu, S.5    Bruun, J.M.6
  • 22
    • 33750620949 scopus 로고    scopus 로고
    • Isomer-specific effect of conjugated linoleic acid on inflammatory adipokines associated with fat accumulation in 3T3-L1 adipocytes
    • Ahn, I. S., B. H. Choi, J. H. Ha, J. M. Byun, H. G. Shin, K. Y. Park, and M. S. Do. 2006. Isomer-specific effect of conjugated linoleic acid on inflammatory adipokines associated with fat accumulation in 3T3-L1 adipocytes. J. Med. Food. 9: 307-312.
    • (2006) J. Med. Food. , vol.9 , pp. 307-312
    • Ahn, I.S.1    Choi, B.H.2    Ha, J.H.3    Byun, J.M.4    Shin, H.G.5    Park, K.Y.6    Do, M.S.7
  • 23
    • 2942755860 scopus 로고    scopus 로고
    • Conjugated linoleic acid induces human adipocyte delipidation: Autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines
    • DOI 10.1074/jbc.M401766200
    • Brown, J. M., M. S. Boysen, S. Chung, O. Fabiyi, R. F. Morrison, S. Mandrup, and M. K. McIntosh. 2004. Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines. J. Biol. Chem. 279: 26735-26747. (Pubitemid 38798831)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.25 , pp. 26735-26747
    • Brown, J.M.1    Boysen, M.S.2    Chung, S.3    Fabiyi, O.4    Morrison, R.F.5    Mandrup, S.6    McIntosh, M.K.7
  • 24
    • 72249102150 scopus 로고    scopus 로고
    • Conjugated linoleic acid activates AMP-activated protein kinase and reduces adiposity more effectively when used with metformin in mice
    • Jiang, S., Z. Wang, J. J. Riethoven, Y. Xia, J. Miner, and M. Fromm. 2009. Conjugated linoleic acid activates AMP-activated protein kinase and reduces adiposity more effectively when used with metformin in mice. J. Nutr. 139: 2244-2251.
    • (2009) J. Nutr. , vol.139 , pp. 2244-2251
    • Jiang, S.1    Wang, Z.2    Riethoven, J.J.3    Xia, Y.4    Miner, J.5    Fromm, M.6
  • 25
    • 77955276240 scopus 로고    scopus 로고
    • Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells
    • Zhai, J. J., Z. L. Liu, J. M. Li, J. P. Chen, L. Jiang, D. M. Wang, J. Yuan, J. G. Shen, D. P. Yang, and J. Q. Chen. 2010. Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells. J. Nutr. Biochem. 21: 1099-1105.
    • (2010) J. Nutr. Biochem. , vol.21 , pp. 1099-1105
    • Zhai, J.J.1    Liu, Z.L.2    Li, J.M.3    Chen, J.P.4    Jiang, L.5    Wang, D.M.6    Yuan, J.7    Shen, J.G.8    Yang, D.P.9    Chen, J.Q.10
  • 26
    • 70449726656 scopus 로고    scopus 로고
    • Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats
    • Gudbrandsen, O. A., E. Rodríguez, H. Wergedahl, S. Mørk, J. E. Reseland, J. Skorve, A. Palou, and R. K. Berge. 2009. Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. Br. J. Nutr. 102: 803-815.
    • (2009) Br. J. Nutr. , vol.102 , pp. 803-815
    • Gudbrandsen, O.A.1    Rodríguez, E.2    Wergedahl, H.3    Mørk, S.4    Reseland, J.E.5    Skorve, J.6    Palou, A.7    Berge, R.K.8
  • 27
    • 77449092780 scopus 로고    scopus 로고
    • Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: Dissociation of adipocyte hypertrophy from inflammation
    • Yeop Han, C., A. Kargi, M. Omer, C. Chan, M. Wabitsch, K. O'Brien, T. Wight, and A. Chait. 2010. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. Diabetes. 59: 386-396.
    • (2010) Diabetes , vol.59 , pp. 386-396
    • Yeop Han, C.1    Kargi, A.2    Omer, M.3    Chan, C.4    Wabitsch, M.5    O'Brien, K.6    Wight, T.7    Chait, A.8
  • 30
    • 77951166692 scopus 로고    scopus 로고
    • Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage
    • Chakrabarti, P., T. English, J. Shi, C. M. Smas, and K. V. Kandror. 2010. Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage. Diabetes. 59: 775-781.
    • (2010) Diabetes , vol.59 , pp. 775-781
    • Chakrabarti, P.1    English, T.2    Shi, J.3    Smas, C.M.4    Kandror, K.V.5
  • 31
    • 80051849862 scopus 로고    scopus 로고
    • High density lipoprotein (HDL) promotes glucose uptake in adipocytes and glycogen synthesis in muscle cells
    • Zhang, Q., Y. Zhang, H. Feng, R. Guo, L. Jin, R. Wan, L. Wang, C. Chen, and S. Li. 2011. High density lipoprotein (HDL) promotes glucose uptake in adipocytes and glycogen synthesis in muscle cells. PLoS ONE. 6: e23556.
    • (2011) PLoS ONE , vol.6
    • Zhang, Q.1    Zhang, Y.2    Feng, H.3    Guo, R.4    Jin, L.5    Wan, R.6    Wang, L.7    Chen, C.8    Li, S.9
  • 32
    • 34748896026 scopus 로고    scopus 로고
    • Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components
    • DOI 10.1017/S0007114507750882, PII S0007114507750882
    • Laso, N., E. Brugué, J. Vidal, E. Ros, J. A. Arnaiz, X. Carné, S. Vidal, S. Mas, R. Deulofeu, and A. Lafuente. 2007. Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components. Br. J. Nutr. 98: 860-867. (Pubitemid 47487956)
    • (2007) British Journal of Nutrition , vol.98 , Issue.4 , pp. 860-867
    • Laso, N.1    Brugue, E.2    Vidal, J.3    Ros, E.4    Arnaiz, J.A.5    Carne, X.6    Vidal, S.7    Mas, S.8    Deulofeu, R.9    Lafuente, A.10
  • 34
    • 33646792244 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor δ (PPARδ), a novel target site for drug discovery in metabolic syndrome
    • DOI 10.1016/j.phrs.2006.03.019, PII S1043661806000442
    • Takahashi, S., T. Tanaka, T. Kodama, and J. Sakai. 2006. Peroxisome proliferator-activated receptor delta (PPARdelta), a novel target site for drug discovery in metabolic syndrome. Pharmacol. Res. 53: 501-507. (Pubitemid 43767554)
    • (2006) Pharmacological Research , vol.53 , Issue.6 , pp. 501-507
    • Takahashi, S.1    Tanaka, T.2    Kodama, T.3    Sakai, J.4
  • 35
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity
    • DOI 10.1016/S0092-8674(03)00269-1
    • Wang, Y. X., C. H. Lee, S. Tiep, R. T. Yu, J. Ham, H. Kang, and R. M. Evans. 2003. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell. 113: 159-170. (Pubitemid 36514968)
    • (2003) Cell , vol.113 , Issue.2 , pp. 159-170
    • Wang, Y.-X.1    Lee, C.-H.2    Tiep, S.3    Yu, R.T.4    Ham, J.5    Kang, H.6    Evans, R.M.7
  • 36
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten, S., J. Seydoux, J. M. Peters, F. J. Gonzalez, B. Desvergne, and W. Wahli. 1999. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J. Clin. Invest. 103: 1489-1498.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1489-1498
    • Kersten, S.1    Seydoux, J.2    Peters, J.M.3    Gonzalez, F.J.4    Desvergne, B.5    Wahli, W.6
  • 37
    • 0025408816 scopus 로고
    • Effect of beta-adrenergic agonists on lipolysis and lipogenesis by porcine adipose tissue in vitro
    • Peterla, T. A., and C. G. Scanes. 1990. Effect of beta-adrenergic agonists on lipolysis and lipogenesis by porcine adipose tissue in vitro. J. Anim. Sci. 68: 1024-1029.
    • (1990) J. Anim. Sci. , vol.68 , pp. 1024-1029
    • Peterla, T.A.1    Scanes, C.G.2
  • 40
    • 0027008279 scopus 로고
    • Possible new therapeutic approach in diabetes mellitus by inhibition of carnitine palmitoyltransferase 1 (CPT1)
    • Wolf, H. P. 1992. Possible new therapeutic approach in diabetes mellitus by inhibition of carnitine palmitoyltransferase 1 (CPT1). Horm. Metab. Res. Suppl. 26: 62-67. (Pubitemid 23017869)
    • (1992) Hormone and Metabolic Research, Supplement , Issue.26 , pp. 62-67
    • Wolf, H.P.O.1
  • 42
    • 0037044425 scopus 로고    scopus 로고
    • Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: A potential link to fatty acid-induced insulin resistance
    • DOI 10.1161/01.CIR.0000033589.15413.48
    • Risérus, U., S. Basu, S. Jovinge, G. N. Fredrikson, J. Arnlöv, and B. Vessby. 2002. Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Circulation. 106: 1925-1929. (Pubitemid 35176296)
    • (2002) Circulation , vol.106 , Issue.15 , pp. 1925-1929
    • Riserus, U.1    Basu, S.2    Jovinge, S.3    Fredrikson, G.N.4    Arnlov, J.5    Vessby, B.6
  • 45
    • 67549115722 scopus 로고    scopus 로고
    • Effects of conjugated linoleic acid plus n-3 polyunsaturated fatty acids on insulin secretion and estimated insulin sensitivity in men
    • Ahrén, B., A. Mari, C. L. Fyfe, F. Tsofliou, A. A. Sneddon, K. W. Wahle, M. S. Winzell, G. Pacini, and L. M. Williams. 2009. Effects of conjugated linoleic acid plus n-3 polyunsaturated fatty acids on insulin secretion and estimated insulin sensitivity in men. Eur. J. Clin. Nutr. 63: 778-786.
    • (2009) Eur. J. Clin. Nutr. , vol.63 , pp. 778-786
    • Ahrén, B.1    Mari, A.2    Fyfe, C.L.3    Tsofliou, F.4    Sneddon, A.A.5    Wahle, K.W.6    Winzell, M.S.7    Pacini, G.8    Williams, L.M.9
  • 46
    • 33644680390 scopus 로고    scopus 로고
    • Conjugated linoleic acid promotes human adipocyte insulin resistance through NFκB-dependent cytokine production
    • DOI 10.1074/jbc.M508159200
    • Chung, S., J. Brown, J. Provo, R. Hopkins, and M. McIntosh. 2005. Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production. J. Biol. Chem. 280: 38445-38456. (Pubitemid 43853742)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.46 , pp. 38445-38456
    • Chung, S.1    Brown, J.M.2    Provo, J.N.3    Hopkins, R.4    McIntosh, M.K.5
  • 47
    • 0036195963 scopus 로고    scopus 로고
    • Trans-10, cis-12 conjugated linoleic acid increases fatty acid oxidation in 3T3-l1 preadipocytes
    • Evans, M., X. Lin, J. Odle, and M. McIntosh. 2002. Trans-10, cis-12 conjugated linoleic acid increases fatty acid oxidation in 3T3-L1 preadipocytes. J. Nutr. 132: 450-455. (Pubitemid 34208748)
    • (2002) Journal of Nutrition , vol.132 , Issue.3 , pp. 450-455
    • Evans, M.1    Lin, X.2    Odle, J.3    McIntosh, M.4
  • 48
    • 47949121252 scopus 로고    scopus 로고
    • Effects of trans-10, cis-12 conjugated linoleic acid on gene expression and lipid metabolism of adipose tissue of growing pigs
    • José, A. A., M. A. Gama, and D. D. Lanna. 2008. Effects of trans-10, cis-12 conjugated linoleic acid on gene expression and lipid metabolism of adipose tissue of growing pigs. Genet. Mol. Res. 7: 284-294.
    • (2008) Genet. Mol. Res. , vol.7 , pp. 284-294
    • José, A.A.1    Gama, M.A.2    Lanna, D.D.3
  • 51
    • 0028058197 scopus 로고
    • Effect of cheddar cheese consumption on plasma conjugated linoleic acid concentrations in men
    • Huang, Y., L. Luedecke, and T. Schultz. 1994. The effects of cheddar cheese consumption on plasma conjugated linoleicacid concentration in men. Nutr. Res. 14: 373-386. (Pubitemid 24068806)
    • (1994) Nutrition Research , vol.14 , Issue.3 , pp. 373-386
    • Huang, Y.-C.1    Luedecke, L.O.2    Shultz, T.D.3
  • 52
    • 0036729159 scopus 로고    scopus 로고
    • The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects
    • DOI 10.1079/BJN2002615
    • Noone, E. J., H. M. Roche, A. P. Nugent, and M. J. Gibney. 2002. The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. Br. J. Nutr. 88: 243-251. (Pubitemid 34987661)
    • (2002) British Journal of Nutrition , vol.88 , Issue.3 , pp. 243-251
    • Noone, E.J.1    Roche, H.M.2    Nugent, A.P.3    Gibney, M.J.4
  • 53
    • 70449534620 scopus 로고    scopus 로고
    • Conjugated linoleic acid isomers, t10c12 and c9t11, are differentially incorporated into adipose tissue and skeletal muscle in humans
    • Goedecke, J. H., D. E. Rae, C. M. Smuts, E. V. Lambert, and M. O'Shea. 2009. Conjugated linoleic acid isomers, t10c12 and c9t11, are differentially incorporated into adipose tissue and skeletal muscle in humans. Lipids. 44: 983-988.
    • (2009) Lipids , vol.44 , pp. 983-988
    • Goedecke, J.H.1    Rae, D.E.2    Smuts, C.M.3    Lambert, E.V.4    O'Shea, M.5
  • 54
    • 1842427555 scopus 로고    scopus 로고
    • Positional distribution of fatty acids in triacylglycerols from subcutaneous adipose tissue of pigs fed diets enriched with conjugated linoleic acid, corn oil, or beef tallow
    • DOI 10.1016/j.meatsci.2004.01.006, PII S0309174004000245
    • King, D. A., J. M. Behrends, B. E. Jenschke, R. D. Rhoades, and S. B. Smith. 2004. Positional distribution of fatty acids in triacylglycerols from subcutaneous adipose tissue of pigs fed diets enriched with conjugated linoleic acid, corn oil, or beef tallow. Meat Sci. 67: 675-681. (Pubitemid 38416890)
    • (2004) Meat Science , vol.67 , Issue.4 , pp. 675-681
    • King, D.A.1    Behrends, J.M.2    Jenschke, B.E.3    Rhoades, R.D.4    Smith, S.B.5
  • 56
    • 78449256948 scopus 로고    scopus 로고
    • Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosis
    • Henique, C., A. Mansouri, G. Fumey, V. Lenoir, J. Girard, F. Bouillaud, C. Prip-Buus, and I. Cohen. 2010. Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosis. J. Biol. Chem. 285: 36818-36827.
    • (2010) J. Biol. Chem. , vol.285 , pp. 36818-36827
    • Henique, C.1    Mansouri, A.2    Fumey, G.3    Lenoir, V.4    Girard, J.5    Bouillaud, F.6    Prip-Buus, C.7    Cohen, I.8
  • 57
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle, P. J., P. B. Garland, C. N. Hales, and E. A. Newsholme. 1963. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet. 1: 785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 58
    • 69049098306 scopus 로고    scopus 로고
    • The Randle cycle revisited: A new head for an old hat
    • Hue, L., and H. Taegtmeyer. 2009. The Randle cycle revisited: a new head for an old hat. Am. J. Physiol. Endocrinol. Metab. 297: E578-E591.
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297
    • Hue, L.1    Taegtmeyer, H.2
  • 59
    • 77953507643 scopus 로고    scopus 로고
    • Inflammation and insulin resistance induced by trans-10, cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes
    • Kennedy, A., K. Martinez, S. Chung, K. LaPoint, R. Hopkins, S. F. Schmidt, K. Andersen, S. Mandrup, and M. McIntosh. 2010. Inflammation and insulin resistance induced by trans-10, cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes. J. Lipid Res. 51: 1906-1917.
    • (2010) J. Lipid Res. , vol.51 , pp. 1906-1917
    • Kennedy, A.1    Martinez, K.2    Chung, S.3    Lapoint, K.4    Hopkins, R.5    Schmidt, S.F.6    Andersen, K.7    Mandrup, S.8    McIntosh, M.9
  • 60
    • 77952910553 scopus 로고    scopus 로고
    • Trans-10,cis-12-Conjugated linoleic acid instigates inflammation in human adipocytes compared with preadipocytes
    • Martinez, K., A. Kennedy, T. West, D. Milatovic, M. Aschner, and M. McIntosh. 2010. trans-10,cis-12-Conjugated linoleic acid instigates inflammation in human adipocytes compared with preadipocytes. J. Biol. Chem. 285: 17701-17712.
    • (2010) J. Biol. Chem. , vol.285 , pp. 17701-17712
    • Martinez, K.1    Kennedy, A.2    West, T.3    Milatovic, D.4    Aschner, M.5    McIntosh, M.6
  • 61
    • 33846248378 scopus 로고    scopus 로고
    • Dietary fish oil n-3 fatty acids increase regulatory cytokine production and exert anti-inflammatory effects in two murine models of inflammation
    • DOI 10.1007/s11745-006-5061-2
    • Sierra, S., F. Lara-Villoslada, M. Comalada, M. Olivares, and J. Xaus. 2006. Dietary fish oil n-3 fatty acids increase regulatory cytokine production and exert anti-inflammatory effects in two murine models of inflammation. Lipids. 41: 1115-1125. (Pubitemid 46095224)
    • (2006) Lipids , vol.41 , Issue.12 , pp. 1115-1125
    • Sierra, S.1    Lara-Villoslada, F.2    Comalada, M.3    Olivares, M.4    Xaus, J.5
  • 63
    • 79958786534 scopus 로고    scopus 로고
    • Activated AMPK and prostaglandins are involved in the response to conjugated linoleic acid and are sufficient to cause lipid reductions in adipocytes
    • Jiang, S., H. Chen, Z. Wang, J. J. Riethoven, Y. Xia, J. Miner, and M. Fromm. 2011. Activated AMPK and prostaglandins are involved in the response to conjugated linoleic acid and are sufficient to cause lipid reductions in adipocytes. J. Nutr. Biochem. 22: 656-664.
    • (2011) J. Nutr. Biochem. , vol.22 , pp. 656-664
    • Jiang, S.1    Chen, H.2    Wang, Z.3    Riethoven, J.J.4    Xia, Y.5    Miner, J.6    Fromm, M.7
  • 64
    • 33745183847 scopus 로고    scopus 로고
    • Functions of AMP-activated protein kinase in adipose tissue
    • DOI 10.1113/jphysiol.2006.111484
    • Daval, M., F. Foufelle, and P. Ferré. 2006. Functions of AMPactivated protein kinase in adipose tissue. J. Physiol. 574: 55-62. (Pubitemid 43905796)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 55-62
    • Daval, M.1    Foufelle, F.2    Ferre, P.3
  • 65
    • 33847009048 scopus 로고    scopus 로고
    • AICAR potentiates ROS production induced by chronic high glucose: Roles of AMPK in pancreatic β-cell apoptosis
    • DOI 10.1016/j.cellsig.2006.10.004, PII S0898656806002737
    • Kim, W. H., J. W. Lee, Y. H. Suh, H. J. Lee, S. H. Lee, Y. K. Oh, B. Gao, and M. H. Jung. 2007. AICAR potentiates ROS production induced by chronic high glucose: roles of AMPK in pancreatic betacell apoptosis. Cell. Signal. 19: 791-805. (Pubitemid 46275369)
    • (2007) Cellular Signalling , vol.19 , Issue.4 , pp. 791-805
    • Kim, W.-H.1    Lee, J.W.2    Suh, Y.H.3    Lee, H.J.4    Lee, S.H.5    Oh, Y.K.6    Gao, B.7    Jung, M.H.8
  • 66
    • 58149358854 scopus 로고    scopus 로고
    • Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes
    • Xie, Z., J. Zhang, J. Wu, B. Viollet, and M. H. Zou. 2008. Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes. Diabetes. 57: 3222-3230.
    • (2008) Diabetes , vol.57 , pp. 3222-3230
    • Xie, Z.1    Zhang, J.2    Wu, J.3    Viollet, B.4    Zou, M.H.5
  • 67
    • 0037122766 scopus 로고    scopus 로고
    • Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
    • DOI 10.1038/415339a
    • Minokoshi, Y., Y. B. Kim, O. D. Peroni, L. G. Fryer, C. Müller, D. Carling, and B. B. Kahn. 2002. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature. 415: 339-343. (Pubitemid 34087557)
    • (2002) Nature , vol.415 , Issue.6869 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.-B.2    Peroni, O.D.3    Fryer, L.G.D.4    Muller, C.5    Carling, D.6    Kahn, B.B.7
  • 70
    • 57049084022 scopus 로고    scopus 로고
    • Time course of high-fat diet-induced reductions in adipose tissue mitochondrial proteins: Potential mechanisms and the relationship to glucose intolerance
    • Sutherland, L. N., L. C. Capozzi, N. J. Turchinsky, R. C. Bell, and D. C. Wright. 2008. Time course of high-fat diet-induced reductions in adipose tissue mitochondrial proteins: potential mechanisms and the relationship to glucose intolerance. Am. J. Physiol. Endocrinol. Metab. 295: E1076-E1083.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295
    • Sutherland, L.N.1    Capozzi, L.C.2    Turchinsky, N.J.3    Bell, R.C.4    Wright, D.C.5
  • 72
    • 84863121852 scopus 로고    scopus 로고
    • Upregulation of UCP2 by adiponectin: The involvement of mitochondrial superoxide and hnRNP K
    • Zhou, M., A. Xu, P. K. Tam, K. S. Lam, B. Huang, Y. Liang, I. K. Lee, D. Wu, and Y. Wang. 2012. Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K. PLoS ONE. 7: e32349.
    • (2012) PLoS ONE , vol.7
    • Zhou, M.1    Xu, A.2    Tam, P.K.3    Lam, K.S.4    Huang, B.5    Liang, Y.6    Lee, I.K.7    Wu, D.8    Wang, Y.9
  • 74
    • 84870302181 scopus 로고    scopus 로고
    • MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
    • Kusminski, C. M., W. L. Holland, K. Sun, J. Park, S. B. Spurgin, Y. Lin, G. R. Askew, J. A. Simcox, D. A. McClain, C. Li, et al. 2012. MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nat. Med. 18: 1539-1549.
    • (2012) Nat. Med. , vol.18 , pp. 1539-1549
    • Kusminski, C.M.1    Holland, W.L.2    Sun, K.3    Park, J.4    Spurgin, S.B.5    Lin, Y.6    Askew, G.R.7    Simcox, J.A.8    McClain, D.A.9    Li, C.10
  • 75
    • 84870670121 scopus 로고    scopus 로고
    • Dietary docosahexaenoic acid (22:6) incorporates into cardiolipin at the expense of linoleic acid (18:2): Analysis and potential implications
    • Cortie, C. H., and P. L. Else. 2012. Dietary docosahexaenoic acid (22:6) incorporates into cardiolipin at the expense of linoleic acid (18:2): analysis and potential implications. Int. J. Mol. Sci. 13: 15447-15463.
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 15447-15463
    • Cortie, C.H.1    Else, P.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.