Inflammation and insulin resistance induced by trans-10, cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes

Journal of Lipid Research

Volumn 51, Issue 7, 2010, Pages 1906-1917

  Kennedy, Arion ^a   Martinez, Kristina ^a   Chung, Soonkyu ^b   LaPoint, Kathy ^a   Hopkins, Robin ^a   Schmidt, Soren F ^c   Andersen, Kenneth ^c   Mandrup, Susanne ^c   McIntosh, Michael ^a  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Cell signaling; Fatty acid; Reactive oxygen species

Indexed keywords

CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CONJUGATED LINOLEIC ACID; CYCLOOXYGENASE 2; INSULIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN F2 ALPHA; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; 10,12-OCTADECADIENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C;

ADIPOCYTE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INDUCTION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INSULIN RESISTANCE; PRIORITY JOURNAL; PROMOTER REGION; ADULT; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; METABOLISM; MIDDLE AGED; MITOCHONDRION; MOUSE; PHYSIOLOGY; YOUNG ADULT;

ADIPOCYTES; ADULT; ANIMALS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INSULIN RESISTANCE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LINOLEIC ACIDS, CONJUGATED; MICE; MIDDLE AGED; MITOCHONDRIA; NF-KAPPA B; REACTIVE OXYGEN SPECIES; TYPE C PHOSPHOLIPASES; YOUNG ADULT;

EID: 77953507643     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M005447     Document Type: Article

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