-
1
-
-
1242295282
-
Naturally-occurring CD4+CD25+ immunoregulatory T cells: Central players in the arena of peripheral tolerance
-
Piccirillo, C. A., and E. M. Shevach. 2004. Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance. Semin. Immunol. 16: 81-88.
-
(2004)
Semin. Immunol.
, vol.16
, pp. 81-88
-
-
Piccirillo, C.A.1
Shevach, E.M.2
-
2
-
-
82155170631
-
Thymic and peripheral differentiation of regulatory T cells
-
Lee, H. M., J. L. Bautista, and C. S. Hsieh. 2011. Thymic and peripheral differentiation of regulatory T cells. Adv. Immunol. 112: 25-71.
-
(2011)
Adv. Immunol.
, vol.112
, pp. 25-71
-
-
Lee, H.M.1
Bautista, J.L.2
Hsieh, C.S.3
-
3
-
-
65549123867
-
Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor?
-
Curotto de Lafaille, M. A., and J. J. Lafaille. 2009. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? Immunity 30: 626-635.
-
(2009)
Immunity
, vol.30
, pp. 626-635
-
-
Curotto De Lafaille, M.A.1
Lafaille, J.J.2
-
4
-
-
80054020840
-
Peripheral education of the immune system by colonic commensal microbiota
-
Lathrop, S. K., S. M. Bloom, S. M. Rao, K. Nutsch, C. W. Lio, N. Santacruz, D. A. Peterson, T. S. Stappenbeck, and C. S. Hsieh. 2011. Peripheral education of the immune system by colonic commensal microbiota. Nature 478: 250-254.
-
(2011)
Nature
, vol.478
, pp. 250-254
-
-
Lathrop, S.K.1
Bloom, S.M.2
Rao, S.M.3
Nutsch, K.4
Lio, C.W.5
Santacruz, N.6
Peterson, D.A.7
Stappenbeck, T.S.8
Hsieh, C.S.9
-
5
-
-
77951638740
-
Expression of helios, an ikaros transcription factor family member, differentiates thymic-derived from peripherally induced foxp3+ T regulatory cells
-
Thornton, A. M., P. E. Korty, D. Q. Tran, E. A. Wohlfert, P. E. Murray, Y. Belkaid, and E. M. Shevach. 2010. Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J. Immunol. 184: 3433-3441.
-
(2010)
J. Immunol.
, vol.184
, pp. 3433-3441
-
-
Thornton, A.M.1
Korty, P.E.2
Tran, D.Q.3
Wohlfert, E.A.4
Murray, P.E.5
Belkaid, Y.6
Shevach, E.M.7
-
6
-
-
80052287274
-
Helios expression is a marker of T cell activation and proliferation
-
Akimova, T., U. H. Beier, L. Wang, M. H. Levine, and W. W. Hancock. 2011. Helios expression is a marker of T cell activation and proliferation. PLoS ONE 6: e24226.
-
(2011)
PLoS ONE
, vol.6
-
-
Akimova, T.1
Beier, U.H.2
Wang, L.3
Levine, M.H.4
Hancock, W.W.5
-
7
-
-
84856567623
-
Expression of helios in peripherally induced foxp3+ regulatory T cells
-
Gottschalk, R. A., E. Corse, and J. P. Allison. 2012. Expression of Helios in peripherally induced Foxp3+ regulatory T cells. J. Immunol. 188: 976-980.
-
(2012)
J. Immunol.
, vol.188
, pp. 976-980
-
-
Gottschalk, R.A.1
Corse, E.2
Allison, J.P.3
-
8
-
-
84863360489
-
Oligodeoxynucleotides stabilize helios-expressing foxp3+ human T regulatory cells during in vitro expansion
-
Kim, Y. C., R. Bhairavabhotla, J. Yoon, A. Golding, A. M. Thornton, D. Q. Tran, and E. M. Shevach. 2012. Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion. Blood 119: 2810-2818.
-
(2012)
Blood
, vol.119
, pp. 2810-2818
-
-
Kim, Y.C.1
Bhairavabhotla, R.2
Yoon, J.3
Golding, A.4
Thornton, A.M.5
Tran, D.Q.6
Shevach, E.M.7
-
9
-
-
66649115650
-
Human memory FOXP3+ tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t
-
Ayyoub, M., F. Deknuydt, I. Raimbaud, C. Dousset, L. Leveque, G. Bioley, and D. Valmori. 2009. Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t. Proc. Natl. Acad. Sci. USA 106: 8635-8640.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8635-8640
-
-
Ayyoub, M.1
Deknuydt, F.2
Raimbaud, I.3
Dousset, C.4
Leveque, L.5
Bioley, G.6
Valmori, D.7
-
10
-
-
78650628082
-
Human RORγt+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors
-
Valmori, D., C. Raffin, I. Raimbaud, and M. Ayyoub. 2010. Human RORγt+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors. Proc. Natl. Acad. Sci. USA 107: 19402-19407.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 19402-19407
-
-
Valmori, D.1
Raffin, C.2
Raimbaud, I.3
Ayyoub, M.4
-
11
-
-
81455135858
-
Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of th17 from FOXP3+ naive regulatory T cells
-
Raffin, C., I. Raimbaud, D. Valmori, and M. Ayyoub. 2011. Ex vivo IL-1 receptor type I expression in human CD4+ T cells identifies an early intermediate in the differentiation of Th17 from FOXP3+ naive regulatory T cells. J. Immunol. 187: 5196-5202.
-
(2011)
J. Immunol.
, vol.187
, pp. 5196-5202
-
-
Raffin, C.1
Raimbaud, I.2
Valmori, D.3
Ayyoub, M.4
-
12
-
-
66949171924
-
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
-
Miyara, M., Y. Yoshioka, A. Kitoh, T. Shima, K. Wing, A. Niwa, C. Parizot, C. Taflin, T. Heike, D. Valeyre, et al. 2009. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity 30: 899-911.
-
(2009)
Immunity
, vol.30
, pp. 899-911
-
-
Miyara, M.1
Yoshioka, Y.2
Kitoh, A.3
Shima, T.4
Wing, K.5
Niwa, A.6
Parizot, C.7
Taflin, C.8
Heike, T.9
Valeyre, D.10
-
13
-
-
69549120242
-
Eos mediates foxp3dependent gene silencing in CD4+ regulatory T cells
-
Pan, F., H. Yu, E. V. Dang, J. Barbi, X. Pan, J. F. Grosso, D. Jinasena, S. M. Sharma, E. M. McCadden, D. Getnet, et al. 2009. Eos mediates Foxp3dependent gene silencing in CD4+ regulatory T cells. Science 325: 1142-1146.
-
(2009)
Science
, vol.325
, pp. 1142-1146
-
-
Pan, F.1
Yu, H.2
Dang, E.V.3
Barbi, J.4
Pan, X.5
Grosso, J.F.6
Jinasena, D.7
Sharma, S.M.8
McCadden, E.M.9
Getnet, D.10
-
14
-
-
77955859470
-
Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and foxp3(+) regulatory T cells
-
Gandhi, R., D. Kumar, E. J. Burns, M. Nadeau, B. Dake, A. Laroni, D. Kozoriz, H. L. Weiner, and F. J. Quintana. 2010. Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells. Nat. Immunol. 11: 846-853.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 846-853
-
-
Gandhi, R.1
Kumar, D.2
Burns, E.J.3
Nadeau, M.4
Dake, B.5
Laroni, A.6
Kozoriz, D.7
Weiner, H.L.8
Quintana, F.J.9
-
15
-
-
84864146433
-
Aiolos promotes TH17 differentiation by directly silencing il2 expression
-
Quintana, F. J., H. Jin, E. J. Burns, M. Nadeau, A. Yeste, D. Kumar, M. Rangachari, C. Zhu, S. Xiao, J. Seavitt, et al. 2012. Aiolos promotes TH17 differentiation by directly silencing Il2 expression. Nat. Immunol. 13: 770-777.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 770-777
-
-
Quintana, F.J.1
Jin, H.2
Burns, E.J.3
Nadeau, M.4
Yeste, A.5
Kumar, D.6
Rangachari, M.7
Zhu, C.8
Xiao, S.9
Seavitt, J.10
-
16
-
-
58349116249
-
Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue
-
Wieczorek, G., A. Asemissen, F. Model, I. Turbachova, S. Floess, V. Liebenberg, U. Baron, D. Stauch, K. Kotsch, J. Pratschke, et al. 2009. Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. Cancer Res. 69: 599-608.
-
(2009)
Cancer Res.
, vol.69
, pp. 599-608
-
-
Wieczorek, G.1
Asemissen, A.2
Model, F.3
Turbachova, I.4
Floess, S.5
Liebenberg, V.6
Baron, U.7
Stauch, D.8
Kotsch, K.9
Pratschke, J.10
-
17
-
-
22144466887
-
A peripheral circulating compartment of natural naive CD4 tregs
-
Valmori, D., A. Merlo, N. E. Souleimanian, C. S. Hesdorffer, and M. Ayyoub. 2005. A peripheral circulating compartment of natural naive CD4 Tregs. J. Clin. Invest. 115: 1953-1962.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1953-1962
-
-
Valmori, D.1
Merlo, A.2
Souleimanian, N.E.3
Hesdorffer, C.S.4
Ayyoub, M.5
-
18
-
-
79958074214
-
Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of foxp3 expression
-
Serre, K., C. Bénézech, G. Desanti, S. Bobat, K. M. Toellner, R. Bird, S. Chan, P. Kastner, A. F. Cunningham, I. C. Maclennan, and E. Mohr. 2011. Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression. PLoS ONE 6: e20731.
-
(2011)
PLoS ONE
, vol.6
-
-
Serre, K.1
Bénézech, C.2
Desanti, G.3
Bobat, S.4
Toellner, K.M.5
Bird, R.6
Chan, S.7
Kastner, P.8
Cunningham, A.F.9
Maclennan, I.C.10
Mohr, E.11
-
19
-
-
65549136983
-
Mechanisms of foxp3+ T regulatory cell-mediated suppression
-
Shevach, E. M. 2009. Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 30: 636-645.
-
(2009)
Immunity
, vol.30
, pp. 636-645
-
-
Shevach, E.M.1
-
20
-
-
39149118909
-
Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ tregs
-
Tosello, V., K. Odunsi, N. E. Souleimanian, S. Lele, P. Shrikant, L. J. Old, D. Valmori, and M. Ayyoub. 2008. Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs. Clin. Immunol. 126: 291-302.
-
(2008)
Clin. Immunol.
, vol.126
, pp. 291-302
-
-
Tosello, V.1
Odunsi, K.2
Souleimanian, N.E.3
Lele, S.4
Shrikant, P.5
Old, L.J.6
Valmori, D.7
Ayyoub, M.8
-
21
-
-
0033554726
-
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
-
Sallusto, F., D. Lenig, R. Förster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401: 708-712.
-
(1999)
Nature
, vol.401
, pp. 708-712
-
-
Sallusto, F.1
Lenig, D.2
Förster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
22
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
-
Liu, W., A. L. Putnam, Z. Xu-Yu, G. L. Szot, M. R. Lee, S. Zhu, P. A. Gottlieb, P. Kapranov, T. R. Gingeras, B. Fazekas de St Groth, et al. 2006. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J. Exp. Med. 203: 1701-1711.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
Gottlieb, P.A.7
Kapranov, P.8
Gingeras, T.R.9
De St Groth, B.F.10
-
23
-
-
34548755672
-
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells
-
Baron, U., S. Floess, G. Wieczorek, K. Baumann, A. Grützkau, J. Dong, A. Thiel, T. J. Boeld, P. Hoffmann, M. Edinger, et al. 2007. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. Eur. J. Immunol. 37: 2378-2389.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 2378-2389
-
-
Baron, U.1
Floess, S.2
Wieczorek, G.3
Baumann, K.4
Grützkau, A.5
Dong, J.6
Thiel, A.7
Boeld, T.J.8
Hoffmann, P.9
Edinger, M.10
-
24
-
-
23944509107
-
Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function
-
Peng, G., Z. Guo, Y. Kiniwa, K. S. Voo, W. Peng, T. Fu, D. Y. Wang, Y. Li, H. Y. Wang, and R. F. Wang. 2005. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 309: 1380-1384.
-
(2005)
Science
, vol.309
, pp. 1380-1384
-
-
Peng, G.1
Guo, Z.2
Kiniwa, Y.3
Voo, K.S.4
Peng, W.5
Fu, T.6
Wang, D.Y.7
Li, Y.8
Wang, H.Y.9
Wang, R.F.10
-
25
-
-
55149105005
-
The Interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress
-
O'Neill, L. A. 2008. The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol. Rev. 226: 10-18.
-
(2008)
Immunol. Rev.
, vol.226
, pp. 10-18
-
-
O'Neill, L.A.1
-
26
-
-
45149109643
-
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ foxp3+ RORgamma t+ T cells
-
Lochner, M., L. Peduto, M. Cherrier, S. Sawa, F. Langa, R. Varona, D. Riethmacher, M. Si-Tahar, J. P. Di Santo, and G. Eberl. 2008. In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells. J. Exp. Med. 205: 1381-1393.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1381-1393
-
-
Lochner, M.1
Peduto, L.2
Cherrier, M.3
Sawa, S.4
Langa, F.5
Varona, R.6
Riethmacher, D.7
Si-Tahar, M.8
Di Santo, J.P.9
Eberl, G.10
-
27
-
-
77954738601
-
Inducible foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
-
Round, J. L., and S. K. Mazmanian. 2010. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc. Natl. Acad. Sci. USA 107: 12204-12209.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 12204-12209
-
-
Round, J.L.1
Mazmanian, S.K.2
-
28
-
-
77957371028
-
Stability of the regulatory T cell lineage in vivo
-
Rubtsov, Y. P., R. E. Niec, S. Josefowicz, L. Li, J. Darce, D. Mathis, C. Benoist, and A. Y. Rudensky. 2010. Stability of the regulatory T cell lineage in vivo. Science 329: 1667-1671.
-
(2010)
Science
, vol.329
, pp. 1667-1671
-
-
Rubtsov, Y.P.1
Niec, R.E.2
Josefowicz, S.3
Li, L.4
Darce, J.5
Mathis, D.6
Benoist, C.7
Rudensky, A.Y.8
-
29
-
-
15444363794
-
T cells that cannot respond to TGF-beta escape control by CD4 (+)CD25(+) regulatory T cells
-
Fahlén, L., S. Read, L. Gorelik, S. D. Hurst, R. L. Coffman, R. A. Flavell, and F. Powrie. 2005. T cells that cannot respond to TGF-beta escape control by CD4 (+)CD25(+) regulatory T cells. J. Exp. Med. 201: 737-746.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 737-746
-
-
Fahlén, L.1
Read, S.2
Gorelik, L.3
Hurst, S.D.4
Coffman, R.L.5
Flavell, R.A.6
Powrie, F.7
-
30
-
-
77950628840
-
A role for the transcription factor helios in human CD4(+)CD25(+) regulatory T cells
-
Getnet, D., J. F. Grosso, M. V. Goldberg, T. J. Harris, H. R. Yen, T. C. Bruno, N. M. Durham, E. L. Hipkiss, K. J. Pyle, S. Wada, et al 2010. A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells. Mol. Immunol. 47: 1595-1600.
-
(2010)
Mol. Immunol.
, vol.47
, pp. 1595-1600
-
-
Getnet, D.1
Grosso, J.F.2
Goldberg, M.V.3
Harris, T.J.4
Yen, H.R.5
Bruno, T.C.6
Durham, N.M.7
Hipkiss, E.L.8
Pyle, K.J.9
Wada, S.10
-
31
-
-
84872740201
-
Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells
-
Baine, I., S. Basu, R. Ames, R. S. Sellers, and F. Macian. 2013. Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells. J. Immunol. 190: 1008-1016.
-
(2013)
J. Immunol.
, vol.190
, pp. 1008-1016
-
-
Baine, I.1
Basu, S.2
Ames, R.3
Sellers, R.S.4
Macian, F.5
-
32
-
-
84874232301
-
Helios+ and helios-cells coexist within the natural FOXP3 + T regulatory cell subset in humans
-
Himmel, M. E., K. G. MacDonald, R. V. Garcia, T. S. Steiner, and M. K. Levings. 2013. Helios+ and Helios-cells coexist within the natural FOXP3 + T regulatory cell subset in humans. J. Immunol. 190: 2001-2008.
-
(2013)
J. Immunol.
, vol.190
, pp. 2001-2008
-
-
Himmel, M.E.1
MacDonald, K.G.2
Garcia, R.V.3
Steiner, T.S.4
Levings, M.K.5
-
33
-
-
84876796640
-
Comment on "helios+ and helioscells coexist within the natural FOXP3+ T regulatory cell subset in humans"
-
Ayyoub, M., C. Raffin, and D. Valmori. 2013. Comment on "helios+ and helioscells coexist within the natural FOXP3+ T regulatory cell subset in humans". J. Immunol. 190: 4439-4440.
-
(2013)
J. Immunol.
, vol.190
, pp. 4439-4440
-
-
Ayyoub, M.1
Raffin, C.2
Valmori, D.3
|