Vitamin D in heart failure

Journal of Cardiac Failure

Volumn 19, Issue 10, 2013, Pages 692-711

  Meredith, Anna J ^a   McManus, Bruce M ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b PROOF Centre of Excellence   (Canada)

Author keywords

heart failure; remodeling; Vitamin D

Indexed keywords

25 HYDROXYERGOCALCIFEROL; ALFACALCIDOL; ANGIOTENSIN II; ATRIAL NATRIURETIC FACTOR; BETA CATENIN; BRAIN NATRIURETIC PEPTIDE; CALCITRIOL; CALCIUM; COLECALCIFEROL; GELATINASE A; GELATINASE B; PARATHYROID HORMONE; PARICALCITOL; TISSUE INHIBITOR OF METALLOPROTEINASE; VITAMIN D; VITAMIN D RECEPTOR;

BLOOD VESSEL CALCIFICATION; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CHRONIC KIDNEY DISEASE; CONGESTIVE HEART FAILURE; CORONARY ARTERY LIGATION; DIABETES MELLITUS; DISEASE ASSOCIATION; DYSLIPIDEMIA; EXTRACELLULAR MATRIX; FOLLOW UP; GENE DELETION; HEART FAILURE; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE INJURY; HEART VENTRICLE HYPERTROPHY; HEMODIALYSIS PATIENT; HUMAN; HYPERTENSION; INCIDENCE; INSULIN SENSITIVITY; ISCHEMIC HEART DISEASE; KIDNEY FAILURE; KNOCKOUT MOUSE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LOADING DRUG DOSE; META ANALYSIS (TOPIC); NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROMOTER REGION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGULATORY MECHANISM; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; SCIENTIFIC LITERATURE; SECONDARY HYPERPARATHYROIDISM; SIGNAL TRANSDUCTION; SUDDEN CARDIAC DEATH; SUN EXPOSURE; SYSTEMATIC REVIEW (TOPIC); ULTRAVIOLET RADIATION; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN D METABOLISM; VITAMIN SUPPLEMENTATION; WNT SIGNALING PATHWAY;

HEART FAILURE; REMODELING; VITAMIN D;

ANIMALS; DIETARY SUPPLEMENTS; HEART FAILURE; HUMANS; RECEPTORS, CALCITRIOL; RISK FACTORS; VITAMIN D;

EID: 84885939535     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2013.09.002     Document Type: Review

References (97)

1. A.S. Go, D. Mozaffarian, V.L. Roger, E.J. Benjamin, J.D. Berry, and W.B. Borden Heart disease and stroke statistics - 2013 update: a report from the American Heart Association Circulation 127 2013 e6 e245
2. S. Neubauer The failing heart - an engine out of fuel N Engl J Med 356 2007 1140 1151
3. S. Yusuf, S. Hawken, S. Ounpuu, T. Dans, A. Avezum, and F. Lanas Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study Lancet 364 2004 937 952
4. E. Hypponen, E. Laara, A. Reunanen, M.R. Jarvelin, and S.M. Virtanen Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study Lancet 358 2001 1500 1503
5. M.F. Holick Vitamin D deficiency N Engl J Med 357 2007 266 281
6. S. Chen, D.J. Glenn, W. Ni, C.L. Grigsby, K. Olsen, and M. Nishimoto Expression of the vitamin d receptor is increased in the hypertrophic heart Hypertension 52 2008 1106 1112
7. A. Fleck Latitude and ischaemic heart disease Lancet 1 1989 613
8. D.S. Grimes, E. Hindle, and T. Dyer Sunlight, cholesterol and coronary heart disease QJM 89 1996 579 589
9. A.S. Douglas, M.G. Dunnigan, T.M. Allan, and J.M. Rawles Seasonal variation in coronary heart disease in Scotland J Epidemiol Community Health 49 1995 575 582
10. E.A. Mortimer Jr., R.R. Monson, and B. MacMahon Reduction in mortality from coronary heart disease in men residing at high altitude N Engl J Med 296 1977 581 585
11. F. Enquselassie, A.J. Dobson, H.M. Alexander, and P.L. Steele Seasons, temperature and coronary disease Int J Epidemiol 22 1993 632 636
12. S.G. Rostand Ultraviolet light may contribute to geographic and racial blood pressure differences Hypertension 30 1997 150 156
13. R. Ebert, N. Schutze, J. Adamski, and F. Jakob Vitamin D signaling is modulated on multiple levels in health and disease Mol Cell Endocrinol 248 2006 149 159
14. H.H. Swales, and T.J. Wang Vitamin D and cardiovascular disease risk: emerging evidence Curr Opin Cardiol 25 2010 513 517
15. R. Vieth Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety Am J Clin Nutr 69 1999 842 856
16. R. Vieth, H. Bischoff-Ferrari, B.J. Boucher, B. Dawson-Hughes, C.F. Garland, and R.P. Heaney The urgent need to recommend an intake of vitamin D that is effective Am J Clin Nutr 85 2007 649 650
17. J.H. Lee, J.H. O'Keefe, D. Bell, D.D. Hensrud, and M.F. Holick Vitamin D deficiency an important, common, and easily treatable cardiovascular risk factor? J Am Coll Cardiol 52 2008 1949 1956
18. W.B. Grant In defense of the sun: an estimate of changes in mortality rates in the United States if mean serum 25-hydroxyvitamin D levels were raised to 45 ng/mL by solar ultraviolet-B irradiance Dermatoendocrinol 1 2009 207 214
19. W.B. Grant, and G.E. Schuitemaker Health benefits of higher serum 25-hydroxyvitamin D levels in The Netherlands J Steroid Biochem Mol Biol 121 2010 456 458
20. M.K. Thomas, D.M. Lloyd-Jones, R.I. Thadhani, A.C. Shaw, D.J. Deraska, and B.T. Kitch Hypovitaminosis D in medical inpatients N Engl J Med 338 1998 777 783
21. M.F. Holick High prevalence of vitamin D inadequacy and implications for health Mayo Clin Proc 81 2006 353 373
22. S. Nesby-O'Dell, K.S. Scanlon, M.E. Cogswell, C. Gillespie, B.W. Hollis, and A.C. Looker Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: Third National Health and Nutrition Examination Survey, 1988-1994 Am J Clin Nutr 76 2002 187 192
23. R.P. van der Wielen, M.R. Lowik, H. van den Berg, L.C. de Groot, J. Haller, and O. Moreiras Serum vitamin D concentrations among elderly people in Europe Lancet 346 1995 207 210
24. E. Hypponen, and C. Power Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors Am J Clin Nutr 85 2007 860 868
25. A.A. Ginde, M.C. Liu, and C.A. Camargo Jr. Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004 Arch Intern Med 169 2009 626 632
26. D.H. Kim, S. Sabour, U.N. Sagar, S. Adams, and D.J. Whellan Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004) Am J Cardiol 102 2008 1540 1544
27. R.K. Scragg, C.A. Camargo Jr., and R.U. Simpson Relation of serum 25-hydroxyvitamin D to heart rate and cardiac work (from the National Health and Nutrition Examination Surveys) Am J Cardiol 105 2010 122 128
28. J. Kendrick, G. Targher, G. Smits, and M. Chonchol 25-Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Third National Health and Nutrition Examination Survey Atherosclerosis 205 2009 255 260
29. A. Zittermann, S.S. Schleithoff, G. Tenderich, H.K. Berthold, R. Korfer, and P. Stehle Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure? J Am Coll Cardiol 41 2003 105 112
30. T.J. Wang, M.J. Pencina, S.L. Booth, P.F. Jacques, E. Ingelsson, and K. Lanier Vitamin D deficiency and risk of cardiovascular disease Circulation 117 2008 503 511
31. E. Giovannucci, Y. Liu, B.W. Hollis, and E.B. Rimm 25-Hydroxyvitamin D and risk of myocardial infarction in men: a prospective study Arch Intern Med 168 2008 1174 1180
32. H. Dobnig, S. Pilz, H. Scharnagl, W. Renner, U. Seelhorst, and B. Wellnitz Independent association of low serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels with all-cause and cardiovascular mortality Arch Intern Med 168 2008 1340 1349
33. S. Pilz, W. Marz, B. Wellnitz, U. Seelhorst, A. Fahrleitner-Pammer, and H.P. Dimai Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography J Clin Endocrinol Metab 93 2008 3927 3935
34. A.A. Ginde, R. Scragg, R.S. Schwartz, and C.A. Camargo Jr. Prospective study of serum 25-hydroxyvitamin D level, cardiovascular disease mortality, and all-cause mortality in older U.S. adults J Am Geriatr Soc 57 2009 1595 1603
35. R.S. Boxer, D.A. Dauser, S.J. Walsh, W.D. Hager, and A.M. Kenny The association between vitamin D and inflammation with the 6-minute walk and frailty in patients with heart failure J Am Geriatr Soc 56 2008 454 461
36. A. Zittermann, S.S. Schleithoff, C. Gotting, O. Dronow, U. Fuchs, and J. Kuhn Poor outcome in end-stage heart failure patients with low circulating calcitriol levels Eur J Heart Fail 10 2008 321 327
37. R. Jorde, M. Sneve, M. Hutchinson, N. Emaus, Y. Figenschau, and G. Grimnes Tracking of serum 25-hydroxyvitamin D levels during 14 years in a population-based study and during 12 months in an intervention study Am J Epidemiol 171 2010 903 908
38. A.D. Wood, K.R. Secombes, F. Thies, L. Aucott, A.J. Black, and A. Mavroeidi Vitamin D3 supplementation has no effect on conventional cardiovascular risk factors: a parallel-group, double-blind, placebo-controlled RCT J Clin Endocrinol Metab 97 2012 3557 3568
39. L.M. Meems, P. van der Harst, W.H. van Gilst, and R.A. de Boer Vitamin D biology in heart failure: molecular mechanisms and systematic review Curr Drug Targets 12 2011 29 41
40. K.E. Watson, M.L. Abrolat, L.L. Malone, J.M. Hoeg, T. Doherty, and R. Detrano Active serum vitamin D levels are inversely correlated with coronary calcification Circulation 96 1997 1755 1760
41. K.C. Chiu, A. Chu, V.L. Go, and M.F. Saad Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction Am J Clin Nutr 79 2004 820 825
42. G. Isaia, R. Giorgino, and S. Adami High prevalence of hypovitaminosis D in female type 2 diabetic population Diabetes Care 24 2001 1496
43. J. Auwerx, R. Bouillon, and H. Kesteloot Relation between 25-hydroxyvitamin D3, apolipoprotein A-I, and high density lipoprotein cholesterol Arterioscler Thromb 12 1992 671 674
44. S. Bae, S.S. Singh, H. Yu, J.Y. Lee, B.R. Cho, and P.M. Kang Vitamin D signaling pathway plays an important role in the development of heart failure after myocardial infarction J Appl Physiol 114 2013 979 987
45. N. Bodyak, J.C. Ayus, S. Achinger, V. Shivalingappa, Q. Ke, and Y.S. Chen Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animals Proc Natl Acad Sci U S A 104 2007 16810 16815
46. S. Bae, B. Yalamarti, Q. Ke, S. Choudhury, H. Yu, and S.A. Karumanchi Preventing progression of cardiac hypertrophy and development of heart failure by paricalcitol therapy in rats Cardiovasc Res 91 2011 632 639
47. A. Rahman, S. Hershey, S. Ahmed, K. Nibbelink, and R.U. Simpson Heart extracellular matrix gene expression profile in the vitamin D receptor knockout mice J Steroid Biochem Mol Biol 103 2007 416 419
48. S. Chen, C.S. Law, C.L. Grigsby, K. Olsen, T.T. Hong, and Y. Zhang Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy Circulation 124 2011 1838 1847
49. K.T. Weber, W.B. Weglicki, and R.U. Simpson Macro- and micronutrient dyshomeostasis in the adverse structural remodelling of myocardium Cardiovasc Res 81 2009 500 508
50. M. Agarwal, A. Phan, R. Willix Jr., M. Barber, and E.R. Schwarz Is vitamin D deficiency associated with heart failure? A review of current evidence J Cardiovasc Pharmacol Ther 16 2011 354 363
51. L.E. Felkin, E. Lara-Pezzi, R. George, M.H. Yacoub, E.J. Birks, and P.J. Barton Expression of extracellular matrix genes during myocardial recovery from heart failure after left ventricular assist device support J Heart Lung Transplant 28 2009 117 122
52. P. Rouet-Benzineb, J.M. Buhler, P. Dreyfus, A. Delcourt, R. Dorent, and J. Perennec Altered balance between matrix gelatinases (MMP-2 and MMP-9) and their tissue inhibitors in human dilated cardiomyopathy: potential role of MMP-9 in myosin-heavy chain degradation Eur J Heart Fail 1 1999 337 352
53. V. Polyakova, I. Loeffler, S. Hein, S. Miyagawa, I. Piotrowska, and S. Dammer Fibrosis in endstage human heart failure: severe changes in collagen metabolism and MMP/TIMP profiles Int J Cardiol 151 2011 18 33
54. P. Mancuso, A. Rahman, S.D. Hershey, L. Dandu, K.A. Nibbelink, and R.U. Simpson 1,25-Dihydroxyvitamin-D3 treatment reduces cardiac hypertrophy and left ventricular diameter in spontaneously hypertensive heart failure-prone (cp/+) rats independent of changes in serum leptin J Cardiovasc Pharmacol 51 2008 559 564
55. Y. Li, B.C. Spataro, J. Yang, C. Dai, and Y. Liu 1,25-Dihydroxyvitamin D inhibits renal interstitial myofibroblast activation by inducing hepatocyte growth factor expression Kidney Int 68 2005 1500 1510
56. A.M. Ramirez, C. Wongtrakool, T. Welch, A. Steinmeyer, U. Zugel, and J. Roman Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells J Steroid Biochem Mol Biol 118 2010 142 150
57. W. He, Y.S. Kang, C. Dai, and Y. Liu Blockade of Wnt/beta-catenin signaling by paricalcitol ameliorates proteinuria and kidney injury J Am Soc Nephrol 22 2011 90 103
58. S. Shah, M.N. Islam, S. Dakshanamurthy, I. Rizvi, M. Rao, and R. Herrell The molecular basis of vitamin D receptor and beta-catenin crossregulation Mol Cell 21 2006 799 809
59. M.J. Larriba, P. Ordonez-Moran, I. Chicote, G. Martin-Fernandez, I. Puig, and A. Munoz Vitamin D receptor deficiency enhances Wnt/beta-catenin signaling and tumor burden in colon cancer PLoS One 6 2011 e23524
60. R.E. Stubbins, A. Hakeem, and N.P. Nunez Using components of the vitamin D pathway to prevent and treat colon cancer Nutr Rev 70 2012 721 729
61. M.E. Beildeck, M. Islam, S. Shah, J. Welsh, and S.W. Byers Control of TCF-4 expression by VDR and vitamin D in the mouse mammary gland and colorectal cancer cell lines PLoS One 4 2009 e7872
62. 2+ release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction J Mol Cell Cardiol 50 2011 390 400
63. R.E. Weishaar, and R.U. Simpson Vitamin D3 and cardiovascular function in rats J Clin Invest 79 1987 1706 1712
64. R.E. Weishaar, S.N. Kim, D.E. Saunders, and R.U. Simpson Involvement of vitamin D3 with cardiovascular function. III. Effects on physical and morphological properties Am J Physiol 258 1990 E134 E142
65. R.U. Simpson, G.A. Thomas, and A.J. Arnold Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscle J Biol Chem 260 1985 8882 8891
66. D.X. Tishkoff, K.A. Nibbelink, K.H. Holmberg, L. Dandu, and R.U. Simpson Functional vitamin D receptor (VDR) in the T-tubules of cardiac myocytes: VDR knockout cardiomyocyte contractility Endocrinology 149 2008 558 564
67. C.W. Park, Y.S. Oh, Y.S. Shin, C.M. Kim, Y.S. Kim, and S.Y. Kim Intravenous calcitriol regresses myocardial hypertrophy in hemodialysis patients with secondary hyperparathyroidism Am J Kidney Dis 33 1999 73 81
68. R.J. McGonigle, M.B. Fowler, A.B. Timmis, M.J. Weston, and V. Parsons Uremic cardiomyopathy: potential role of vitamin D and parathyroid hormone Nephron 36 1984 94 100
69. 2D3 suppresses expression and secretion of atrial natriuretic peptide from cardiac myocytes Am J Physiol 268 1995 E1108 E1113
70. J. Wu, M. Garami, T. Cheng, and D.G. Gardner 1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes J Clin Invest 97 1996 1577 1588
71. M. Freundlich, Y. Quiroz, Z. Zhang, Y. Zhang, Y. Bravo, and J.R. Weisinger Suppression of renin-angiotensin gene expression in the kidney by paricalcitol Kidney Int 74 2008 1394 1402
72. I.H. Porsti Expanding targets of vitamin D receptor activation: downregulation of several RAS components in the kidney Kidney Int 74 2008 1371 1373
73. R.S. Vasan, L.M. Sullivan, R. Roubenoff, C.A. Dinarello, T. Harris, and E.J. Benjamin Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study Circulation 107 2003 1486 1491
74. S.S. Schleithoff, A. Zittermann, G. Tenderich, H.K. Berthold, P. Stehle, and R. Koerfer Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial Am J Clin Nutr 83 2006 754 759
75. K. Muller, P.M. Haahr, M. Diamant, K. Rieneck, A. Kharazmi, and K. Bendtzen 1,25-Dihydroxyvitamin D3 inhibits cytokine production by human blood monocytes at the post-transcriptional level Cytokine 4 1992 506 512
76. W. Lee, and P.M. Kang Vitamin D deficiency and cardiovascular disease: is there a role for vitamin D therapy in heart failure? Curr Opin Investig Drugs 11 2010 309 314
77. E.A. Gonzalez, A. Sachdeva, D.A. Oliver, and K.J. Martin Vitamin D insufficiency and deficiency in chronic kidney disease. A single center observational study Am J Nephrol 24 2004 503 510
78. A. Levin, G.L. Bakris, M. Molitch, M. Smulders, J. Tian, and L.A. Williams Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease Kidney Int 71 2007 31 38
79. G. Coen, D. Mantella, M. Manni, A. Balducci, I. Nofroni, and D. Sardella 25-Hydroxyvitamin D levels and bone histomorphometry in hemodialysis renal osteodystrophy Kidney Int 68 2005 1840 1848
80. M. Wolf, A. Shah, O. Gutierrez, E. Ankers, M. Monroy, and H. Tamez Vitamin D levels and early mortality among incident hemodialysis patients Kidney Int 72 2007 1004 1013
81. S.G. Achinger, and J.C. Ayus The role of vitamin D in left ventricular hypertrophy and cardiac function Kidney Int Suppl 95 2005 S37 S42
82. United States Renal Data System 1999 Annual Data Report Am J Kidney Dis 34 1999 S87 S94
83. A. Zittermann, S.S. Schleithoff, and R. Koerfer Vitamin D and vascular calcification Curr Opin Lipidol 18 2007 41 46
84. H.W. Kim, C.W. Park, Y.S. Shin, Y.S. Kim, S.J. Shin, and E.J. Choi Calcitriol regresses cardiac hypertrophy and QT dispersion in secondary hyperparathyroidism on hemodialysis Nephron Clin Pract 102 2006 c21 c29
85. E. Hagstrom, P. Hellman, T.E. Larsson, E. Ingelsson, L. Berglund, and J. Sundstrom Plasma parathyroid hormone and the risk of cardiovascular mortality in the community Circulation 119 2009 2765 2771
86. B. Kestenbaum, R. Katz, I. de Boer, A. Hoofnagle, M.J. Sarnak, and M.G. Shlipak Vitamin D, parathyroid hormone, and cardiovascular events among older adults J Am Coll Cardiol 58 2011 1433 1441
87. F.N. Saleh, H. Schirmer, J. Sundsfjord, and R. Jorde Parathyroid hormone and left ventricular hypertrophy Eur Heart J 24 2003 2054 2060
88. A.J. van Ballegooijen, M. Visser, M.F. Cotch, A.E. Arai, M. Garcia, and T.B. Harris Serum vitamin D and parathyroid hormone in relation to cardiac structure and function: the ICELAND-MI substudy of AGES-Reykjavik J Clin Endocrinol Metab 98 2013 2544 2552
89. P. Autier, and S. Gandini Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials Arch Intern Med 167 2007 1730 1737
90. L. Wang, J.E. Manson, Y. Song, and H.D. Sesso Systematic review: vitamin D and calcium supplementation in prevention of cardiovascular events Ann Intern Med 152 2010 315 323
91. I. Gotsman, A. Shauer, D.R. Zwas, Y. Hellman, A. Keren, and C. Lotan Vitamin D deficiency is a predictor of reduced survival in patients with heart failure; vitamin D supplementation improves outcome Eur J Heart Fail 14 2012 357 366
92. J. Hsia, G. Heiss, H. Ren, M. Allison, N.C. Dolan, and P. Greenland Calcium/vitamin D supplementation and cardiovascular events Circulation 115 2007 846 854
93. A. Zittermann, S.S. Schleithoff, and R. Koerfer Regarding article, "Calcium/vitamin D supplementation and cardiovascular events" [letter] Circulation 116 2007 e85
94. M.J. Bolland, P.A. Barber, R.N. Doughty, B. Mason, A. Horne, and R. Ames Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial BMJ 336 2008 262 266
95. M.J. Bolland, A. Avenell, J.A. Baron, A. Grey, G.S. MacLennan, and G.D. Gamble Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis BMJ 341 2010 c3691
96. J.M. Lappe, and R.P. Heaney Why randomized controlled trials of calcium and vitamin D sometimes fail Dermatoendocrinol 4 2012 95 100
97. J.J. Green, D.A. Robinson, G.E. Wilson, R.U. Simpson, and M.V. Westfall Calcitriol modulation of cardiac contractile performance via protein kinase C J Mol Cell Cardiol 41 2006 350 359