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Volumn 7, Issue 3, 2010, Pages

Alternative polyadenylation of MeCP2: Influence of cis-acting elements and trans-acting factors

Author keywords

3 ; Cis acting elements; MeCP2; Polyadenylation; Trans acting factors; Untranslated region (3 UTR)

Indexed keywords

MECP2 PROTEIN, HUMAN; METHYL CPG BINDING PROTEIN 2; TRANSACTIVATOR PROTEIN;

EID: 85046916288     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.7.3.11564     Document Type: Article
Times cited : (26)

References (34)
  • 1
    • 0036364652 scopus 로고    scopus 로고
    • A history of poly a sequences: From formation to factors to function
    • Edmonds M. A history of poly A sequences: from formation to factors to function. Prog Nucleic Acid Res Mol Biol 2002; 71:285-389.
    • (2002) Prog Nucleic Acid Res Mol Biol , vol.71 , pp. 285-389
    • Edmonds, M.1
  • 2
    • 58149144383 scopus 로고    scopus 로고
    • Alternative polyadenylation: A twist on 3′ end formation
    • Lutz CS. Alternative polyadenylation: a twist on 3′ end formation. ACS Chemical Biol 2008; 3:609-17.
    • (2008) ACS Chemical Biol , vol.3 , pp. 609-617
    • Lutz, C.S.1
  • 3
    • 13744254695 scopus 로고    scopus 로고
    • A large-scale analysis of mRNA polyadenylation of human and mouse genes
    • Tian B, Hu J, Zhang H, Lutz CS. A large-scale analysis of mRNA polyadenylation of human and mouse genes. Nucl Acids Res 2005; 33:201-12.
    • (2005) Nucl Acids Res , vol.33 , pp. 201-212
    • Tian, B.1    Hu, J.2    Zhang, H.3    Lutz, C.S.4
  • 4
    • 0026747761 scopus 로고
    • Purification, sequence and cellular localization of a novel chromosomal protein that binds to methylated DNA
    • Lewis JD, Meehan RR, Henzel WJ, Mauer-Foy I, Jeppesen P, Klein F. Purification, sequence and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 1992; 69:905-14.
    • (1992) Cell , vol.69 , pp. 905-914
    • Lewis, J.D.1    Meehan, R.R.2    Henzel, W.J.3    Mauer-Foy, I.4    Jeppesen, P.5    Klein, F.6
  • 5
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG binding protein 2
    • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG binding protein 2. Nature Genet 1999; 23:185-8.
    • (1999) Nature Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Van Den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 6
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • Chen RZ, Akbarian S, Tudor M, Jaenisch R. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nature Genetics 2001; 27:327-31.
    • (2001) Nature Genetics , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 7
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • Guy J, Hendrich B, Holmes M, Martin JE, Bird A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nature Genet 2001; 27:322-6.
    • (2001) Nature Genet , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 8
    • 0033365401 scopus 로고    scopus 로고
    • Rett syndrom and beyond: Recurrent spontaneous and familial MECP2 mutations at CpG hotspots
    • Wan M, Lee SSJ, Zhang X, Houwink-Manville I, Song HR, Amir RE, et al. Rett syndrom and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots. Am J Hum Genet 1999; 65:1520-9.
    • (1999) Am J Hum Genet , vol.65 , pp. 1520-1529
    • Wan, M.1    Lee, S.S.J.2    Zhang, X.3    Houwink-Manville, I.4    Song, H.R.5    Amir, R.E.6
  • 10
    • 0033763712 scopus 로고    scopus 로고
    • Rett syndrome: A surprising result of mutation in MECP2
    • Dragich J, Houwink-Manville I, Schanen C. Rett syndrome: a surprising result of mutation in MECP2. Hum Mol Genet 2000; 9:2365-75.
    • (2000) Hum Mol Genet , vol.9 , pp. 2365-2375
    • Dragich, J.1    Houwink-Manville, I.2    Schanen, C.3
  • 11
    • 0035118802 scopus 로고    scopus 로고
    • Mutation spectrum in patients with Rett syndrome in the German population: Evidence of hot spot regions
    • Laccone F, Huppke P, Hanefeld F, Meins M. Mutation spectrum in patients with Rett syndrome in the German population: evidence of hot spot regions. Hum Mutation 2001; 17:183-90.
    • (2001) Hum Mutation , vol.17 , pp. 183-190
    • Laccone, F.1    Huppke, P.2    Hanefeld, F.3    Meins, M.4
  • 12
    • 0035853013 scopus 로고    scopus 로고
    • MECP2 gene analysis in classical Rett syndrome and in patients with Rett-like features
    • Auranen M, Vanhala R, Vosman M, Levander M, Varilo T, Hietala M, et al. MECP2 gene analysis in classical Rett syndrome and in patients with Rett-like features. Neurology 2001; 56:611-7.
    • (2001) Neurology , vol.56 , pp. 611-617
    • Auranen, M.1    Vanhala, R.2    Vosman, M.3    Levander, M.4    Varilo, T.5    Hietala, M.6
  • 13
    • 0035129277 scopus 로고    scopus 로고
    • A detailed analysis of the MECP2gene: Prevalence of recurrent mutations and gross DNA rearrangements in Rett syndrome patients
    • Bourdon V, Phillipe C, Labrune O, Amsallem D, Arnould C, Jonveaux P. A detailed analysis of the MECP2gene: prevalence of recurrent mutations and gross DNA rearrangements in Rett syndrome patients. Hum Genet 2001; 108:43-50.
    • (2001) Hum Genet , vol.108 , pp. 43-50
    • Bourdon, V.1    Phillipe, C.2    Labrune, O.3    Amsallem, D.4    Arnould, C.5    Jonveaux, P.6
  • 15
    • 3042847437 scopus 로고    scopus 로고
    • MECP2 structural and 3′-UTR variants in schizophrenia, autism and other psychiatric diseases: A possible association with autism
    • Shibayama A, Cook EH Jr, Feng J, Glanzmann C, Yan J, Craddock N, et al. MECP2 structural and 3′-UTR variants in schizophrenia, autism and other psychiatric diseases: a possible association with autism. Am J Med Genet B Neuropsychiatr Genet 2004; 128:50-3.
    • (2004) Am J Med Genet B Neuropsychiatr Genet , vol.128 , pp. 50-53
    • Shibayama, A.1    Cook Jr., E.H.2    Feng, J.3    Glanzmann, C.4    Yan, J.5    Craddock, N.6
  • 16
    • 34247096911 scopus 로고    scopus 로고
    • MeCP2 gene mutation analysis in autistic boys with developmental regression
    • Xi CY, Ma HW, Lu Y, Zhao YJ, Hua TY, Zhao Y, et al. MeCP2 gene mutation analysis in autistic boys with developmental regression. Psychiatric Genetics 2007; 17:113-6.
    • (2007) Psychiatric Genetics , vol.17 , pp. 113-116
    • Xi, C.Y.1    Ma, H.W.2    Lu, Y.3    Zhao, Y.J.4    Hua, T.Y.5    Zhao, Y.6
  • 18
    • 0032776138 scopus 로고    scopus 로고
    • A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3′-untranslated region of the methyl-CpG-binding protein 2 gene (MeCp2) suggests a regulatory role in gene expression
    • Coy JF, Sedlacek Z, Bachner D, Delius H, Poustka A. A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3′-untranslated region of the methyl-CpG-binding protein 2 gene (MeCp2) suggests a regulatory role in gene expression. Hum Mol Genet 1999; 8:1253-62.
    • (1999) Hum Mol Genet , vol.8 , pp. 1253-1262
    • Coy, J.F.1    Sedlacek, Z.2    Bachner, D.3    Delius, H.4    Poustka, A.5
  • 19
    • 15244351322 scopus 로고    scopus 로고
    • Distinct expression profiles of Mecp2 transcripts with different lengths of 3′ UTR in the brain and visceral organs during mouse development
    • Pelka GJ, Watson CM, Christodoulou J, Tam PPL. Distinct expression profiles of Mecp2 transcripts with different lengths of 3′ UTR in the brain and visceral organs during mouse development. Genomics 2005; 85:441-52.
    • (2005) Genomics , vol.85 , pp. 441-452
    • Pelka, G.J.1    Watson, C.M.2    Christodoulou, J.3    Tam, P.P.L.4
  • 21
    • 0029120391 scopus 로고
    • Cleavage site determinants in the mammalian polyadenylation signal
    • Chen F, MacDonald CC, Wilusz J. Cleavage site determinants in the mammalian polyadenylation signal. Nucleic Acids Res 1995; 23:2614-20.
    • (1995) Nucleic Acids Res , vol.23 , pp. 2614-2620
    • Chen, F.1    MacDonald, C.C.2    Wilusz, J.3
  • 22
    • 0030789131 scopus 로고    scopus 로고
    • Alternative poly(A) site selction in complex transcriptional units: Means to an end?
    • Edwalds-GilbertG, Veraldi KL, Milcarek C. Alternative poly(A) site selction in complex transcriptional units: means to an end? Nucleic Acids Res 1997; 25:2547-61.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2547-2561
    • Edwalds-Gilbert, G.1    Veraldi, K.L.2    Milcarek, C.3
  • 23
    • 0037089136 scopus 로고    scopus 로고
    • Downstream sequence elements with different affinities for the hnRNP H/H' protein influence the processing efficiency of mammalian polyadenylation signals
    • Arhin GK, Boots M, Bagga PS, Milcarek C, Wilusz J. Downstream sequence elements with different affinities for the hnRNP H/H' protein influence the processing efficiency of mammalian polyadenylation signals. Nucl Acids Res 2002; 30:1842-50.
    • (2002) Nucl Acids Res , vol.30 , pp. 1842-1850
    • Arhin, G.K.1    Boots, M.2    Bagga, P.S.3    Milcarek, C.4    Wilusz, J.5
  • 24
    • 0035145592 scopus 로고    scopus 로고
    • HnRNP F influences binding of a 64-kilodalton subunit of cleavage stimulation factor to mRNA precursors in mouse B cells
    • Veraldi KL, Arhin GK, Martincic K, Chung-Ganster LH, Wilusz J, Milcarek C. hnRNP F influences binding of a 64-kilodalton subunit of cleavage stimulation factor to mRNA precursors in mouse B cells. Mol Cell Biol 2001; 21:1228-38.
    • (2001) Mol Cell Biol , vol.21 , pp. 1228-1238
    • Veraldi, K.L.1    Arhin, G.K.2    Martincic, K.3    Chung-Ganster, L.H.4    Wilusz, J.5    Milcarek, C.6
  • 25
    • 0032404113 scopus 로고    scopus 로고
    • DSEF-1 is a member of the hnRNP H family of RNA-binding proteins and stimulates pre-mRNA cleavage and polyadenylation in vitro
    • Bagga PS, Arhin GK, Wilusz J. DSEF-1 is a member of the hnRNP H family of RNA-binding proteins and stimulates pre-mRNA cleavage and polyadenylation in vitro. Nucleic Acids Res 1998; 26:5343-50.
    • (1998) Nucleic Acids Res , vol.26 , pp. 5343-5350
    • Bagga, P.S.1    Arhin, G.K.2    Wilusz, J.3
  • 26
    • 30044446861 scopus 로고    scopus 로고
    • The hnRNPs F and H2 bind to similar sequences to influence gene expression
    • Alkan SA, Martincic K, Milcarek C. The hnRNPs F and H2 bind to similar sequences to influence gene expression. Biochem J 2006; 393:361-71.
    • (2006) Biochem J , vol.393 , pp. 361-371
    • Alkan, S.A.1    Martincic, K.2    Milcarek, C.3
  • 27
    • 0032526887 scopus 로고    scopus 로고
    • Auxiliary downstream elements are required for efficient polyadenylation of mammalian pre-mRNAs
    • Chen F, Wilusz J. Auxiliary downstream elements are required for efficient polyadenylation of mammalian pre-mRNAs. Nucleic Acids Res 1998; 26:2891-8.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2891-2898
    • Chen, F.1    Wilusz, J.2
  • 28
    • 0037044739 scopus 로고    scopus 로고
    • Upstream elements present in the 3′ untranslated region of collagen genes influence the processing efficiency of overlapping polyadenylation signals
    • Natalizio BJ, Muniz LC, Arhin GK, Wilusz J, Lutz CS. Upstream elements present in the 3′ untranslated region of collagen genes influence the processing efficiency of overlapping polyadenylation signals. J Biol Chem 2002; 277:42733-40.
    • (2002) J Biol Chem , vol.277 , pp. 42733-42740
    • Natalizio, B.J.1    Muniz, L.C.2    Arhin, G.K.3    Wilusz, J.4    Lutz, C.S.5
  • 29
    • 0028269622 scopus 로고
    • Direct interaction of the U1snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal
    • Lutz CS, Alwine JC. Direct interaction of the U1snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal. Genes & Dev 1994; 8:576-86.
    • (1994) Genes & Dev , vol.8 , pp. 576-586
    • Lutz, C.S.1    Alwine, J.C.2
  • 31
    • 0032953308 scopus 로고    scopus 로고
    • HnRNP H is a component of splicing enhancer complex that activates a c-src alternative exon in neuronal cells
    • Chou MY, Rooke N, Turke CW, Black DL. hnRNP H is a component of splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Mol Cell Biol 1999; 19:69-77.
    • (1999) Mol Cell Biol , vol.19 , pp. 69-77
    • Chou, M.Y.1    Rooke, N.2    Turke, C.W.3    Black, D.L.4
  • 32
    • 0028867814 scopus 로고
    • The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event
    • Min H, Chan RC, Black DL. The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event. Genes Dev 1995; 9:2659-71.
    • (1995) Genes Dev , vol.9 , pp. 2659-2671
    • Min, H.1    Chan, R.C.2    Black, D.L.3
  • 33
    • 77953284100 scopus 로고    scopus 로고
    • Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation
    • epub ahead of print
    • Millevoi S, Vagner S. Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation. Nucl Acids Res 2009; epub ahead of print.
    • (2009) Nucl Acids Res
    • Millevoi, S.1    Vagner, S.2
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-DeltaDeltaC(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-DeltaDeltaC(T)) Method. Methods 2001; 25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.