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Volumn 162, Issue 7, 2013, Pages 698-710

Sex differences in the genetic risk for schizophrenia: History of the evidence for sex-specific and sex-dependent effects

Author keywords

Genetic transmission; Hormones; Psychoses; Sex chromosomes; Sex specificity

Indexed keywords

METHYL CPG BINDING PROTEIN 2; MICRORNA; MICRORNA 137; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 4; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; ZINC FINGER NUCLEASE;

EID: 84885790133     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.32159     Document Type: Review
Times cited : (77)

References (153)
  • 1
    • 79957485070 scopus 로고    scopus 로고
    • Covariance modeling of MRI brain volumes in memory circuitry in schizophrenia: Sex differences are critical
    • Abbs B, Liang L, Makris N, Tsuang MT, Seidman LJ, Goldstein JM. 2011. Covariance modeling of MRI brain volumes in memory circuitry in schizophrenia: Sex differences are critical. NeuroImage 56(4):1865-1874.
    • (2011) NeuroImage , vol.56 , Issue.4 , pp. 1865-1874
    • Abbs, B.1    Liang, L.2    Makris, N.3    Tsuang, M.T.4    Seidman, L.J.5    Goldstein, J.M.6
  • 3
    • 67749091002 scopus 로고    scopus 로고
    • Searching genetic risk factors for schizophrenia and bipolar disorder: Learn from the past and back to the future
    • Alaerts M, Del-Favero J. 2009. Searching genetic risk factors for schizophrenia and bipolar disorder: Learn from the past and back to the future. Hum Mutat 30(8):1139-1152.
    • (2009) Hum Mutat , vol.30 , Issue.8 , pp. 1139-1152
    • Alaerts, M.1    Del-Favero, J.2
  • 4
    • 0037639116 scopus 로고    scopus 로고
    • Sex differences in the risk of schizophrenia: Evidence from meta-analysis
    • Aleman A, Kahn RS, Selten JP. 2003. Sex differences in the risk of schizophrenia: Evidence from meta-analysis. Arch Gen Psychiatry 60:565-571.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 565-571
    • Aleman, A.1    Kahn, R.S.2    Selten, J.P.3
  • 6
    • 0029819112 scopus 로고    scopus 로고
    • Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease
    • Arolt V, Lencer R, Nolte A, Muller-Myhsok B, Purmann S, Schurmann M, Leutelt J, Pinnow M, Schwinger E. 1996. Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease. Am J Med Genet 67(6):564-579.
    • (1996) Am J Med Genet , vol.67 , Issue.6 , pp. 564-579
    • Arolt, V.1    Lencer, R.2    Nolte, A.3    Muller-Myhsok, B.4    Purmann, S.5    Schurmann, M.6    Leutelt, J.7    Pinnow, M.8    Schwinger, E.9
  • 9
    • 2542424674 scopus 로고    scopus 로고
    • Why genetic investigattion of psychiatric disorders is so difficult
    • Bearden C, Reus V, Freimer N. 2004. Why genetic investigattion of psychiatric disorders is so difficult. Curr Opin Genet Dev 14:280-286.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 280-286
    • Bearden, C.1    Reus, V.2    Freimer, N.3
  • 11
    • 84857039605 scopus 로고    scopus 로고
    • Genome-wide association studies of schizophrenia: Does bigger lead to better results
    • Bergen SE, Petryshen TL. 2012. Genome-wide association studies of schizophrenia: Does bigger lead to better results? Curr Opin Psychiatry 25(2):76-82.
    • (2012) Curr Opin Psychiatry , vol.25 , Issue.2 , pp. 76-82
    • Bergen, S.E.1    Petryshen, T.L.2
  • 12
    • 62649087896 scopus 로고    scopus 로고
    • Polymorphisms in SLC6A4, PAH, GABRB3, and MAOB and modification of psychotic disorder features
    • Bergen SE, Fanous AH, Walsh D, O'Neill FA, Kendler KS. 2009. Polymorphisms in SLC6A4, PAH, GABRB3, and MAOB and modification of psychotic disorder features. Schizophr Res 109(1-3):94-97.
    • (2009) Schizophr Res , vol.109 , Issue.1-3 , pp. 94-97
    • Bergen, S.E.1    Fanous, A.H.2    Walsh, D.3    O'Neill, F.A.4    Kendler, K.S.5
  • 16
    • 0031939076 scopus 로고    scopus 로고
    • The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study
    • Cannon TD, Kaprio J, Lonnqvist J, Huttunen M, Koskenvuo M. 1998. The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study. Arch Gen Psychiatry 55(1):67-74.
    • (1998) Arch Gen Psychiatry , vol.55 , Issue.1 , pp. 67-74
    • Cannon, T.D.1    Kaprio, J.2    Lonnqvist, J.3    Huttunen, M.4    Koskenvuo, M.5
  • 17
    • 63449115452 scopus 로고    scopus 로고
    • Recent adaptive selection at MAOB and ancestral susceptibility to schizophrenia
    • Carrera N, Sanjuan J, Molto MD, Carracedo A, Costas J. 2009. Recent adaptive selection at MAOB and ancestral susceptibility to schizophrenia. Am J Med Genet Part B 150B(3):369-374.
    • (2009) Am J Med Genet Part B , vol.150 B , Issue.3 , pp. 369-374
    • Carrera, N.1    Sanjuan, J.2    Molto, M.D.3    Carracedo, A.4    Costas, J.5
  • 19
    • 0027318632 scopus 로고
    • Sex and schizophrenia: Effects of diagnostic stringency, and associations with premorbid variables
    • Castle DJ, Wessely S, Murray RM. 1993. Sex and schizophrenia: Effects of diagnostic stringency, and associations with premorbid variables. Br J Psychiatry 162:653-664.
    • (1993) Br J Psychiatry , vol.162 , pp. 653-664
    • Castle, D.J.1    Wessely, S.2    Murray, R.M.3
  • 21
    • 56049088492 scopus 로고    scopus 로고
    • Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia
    • Chen Q, Wang X, O'Neill FA, Walsh D, Kendler KS, Chen X. 2008. Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia? Schizophr Res 106(2-3):200-207.
    • (2008) Schizophr Res , vol.106 , Issue.2-3 , pp. 200-207
    • Chen, Q.1    Wang, X.2    O'Neill, F.A.3    Walsh, D.4    Kendler, K.S.5    Chen, X.6
  • 24
    • 0023757520 scopus 로고
    • Sex chromosomes and psychosis: The case for a pseudoautosomal locus
    • Crow TJ. 1988. Sex chromosomes and psychosis: The case for a pseudoautosomal locus. Br J Psychiatry 153:675-683.
    • (1988) Br J Psychiatry , vol.153 , pp. 675-683
    • Crow, T.J.1
  • 25
    • 33846554380 scopus 로고    scopus 로고
    • How and why genetic linkage has not solved the problem of psychosis: Review and hypothesis
    • Crow TJ. 2007. How and why genetic linkage has not solved the problem of psychosis: Review and hypothesis. Am J Psychiatry 164:13-21.
    • (2007) Am J Psychiatry , vol.164 , pp. 13-21
    • Crow, T.J.1
  • 26
    • 47249128993 scopus 로고    scopus 로고
    • Craddock & Owen vs Kraepelin: 85 years late, mesmerised by "polygenes
    • Crow TJ. 2008. Craddock & Owen vs Kraepelin: 85 years late, mesmerised by "polygenes". Schizophr Res 103(1-3):156-160.
    • (2008) Schizophr Res , vol.103 , Issue.1-3 , pp. 156-160
    • Crow, T.J.1
  • 27
    • 84858289514 scopus 로고    scopus 로고
    • Schizophrenia as variation in the sapiens-specific epigenetic instruction to the embryo
    • Crow TJ. 2012. Schizophrenia as variation in the sapiens-specific epigenetic instruction to the embryo. Clin Genet 81(4):319-324.
    • (2012) Clin Genet , vol.81 , Issue.4 , pp. 319-324
    • Crow, T.J.1
  • 28
    • 0024361667 scopus 로고
    • Concordance by sex in sibling pairs with schizophrenia is paternally inherited: Evidence for a pseudoautosomal locus
    • Crow TJ, DeLisi LE, Johnstone EC. 1989. Concordance by sex in sibling pairs with schizophrenia is paternally inherited: Evidence for a pseudoautosomal locus. Br J Psychiatry 155:92-97.
    • (1989) Br J Psychiatry , vol.155 , pp. 92-97
    • Crow, T.J.1    DeLisi, L.E.2    Johnstone, E.C.3
  • 33
    • 0024451016 scopus 로고
    • Evidence for a sex chromosome locus for schizophrenia
    • DeLisi LE, Crow TJ. 1989. Evidence for a sex chromosome locus for schizophrenia. Schizophr Bull 15(3):431-440.
    • (1989) Schizophr Bull , vol.15 , Issue.3 , pp. 431-440
    • DeLisi, L.E.1    Crow, T.J.2
  • 37
    • 64849085415 scopus 로고    scopus 로고
    • A longer duration of schizophrenic illness has sex-specific associations within the working memory neural network in schizophrenia
    • Elsabagh S, Premkumar P, Anilkumar A, Kumari V. 2009. A longer duration of schizophrenic illness has sex-specific associations within the working memory neural network in schizophrenia. Behav Brain Res 201(1):41-47.
    • (2009) Behav Brain Res , vol.201 , Issue.1 , pp. 41-47
    • Elsabagh, S.1    Premkumar, P.2    Anilkumar, A.3    Kumari, V.4
  • 40
    • 0015551456 scopus 로고
    • Genetic and environmental factors in schizophrenia. A study of schizophrenic twins and their families
    • Fischer M. 1973. Genetic and environmental factors in schizophrenia. A study of schizophrenic twins and their families. Acta Psychiatr Scand Suppl 238:9-142.
    • (1973) Acta Psychiatr Scand Suppl , vol.238 , pp. 9-142
    • Fischer, M.1
  • 42
    • 0029874880 scopus 로고    scopus 로고
    • A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12A
    • Gill M, Vallada H, Collier D, Sham P, Holmans P, Murray R, McGuffin P, Nanko S, Owen M, Antonarakis S, et al. 1996. A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12A. Am J Med Genet 67(1):40-45.
    • (1996) Am J Med Genet , vol.67 , Issue.1 , pp. 40-45
    • Gill, M.1    Vallada, H.2    Collier, D.3    Sham, P.4    Holmans, P.5    Murray, R.6    McGuffin, P.7    Nanko, S.8    Owen, M.9    Antonarakis, S.10
  • 43
    • 77952107468 scopus 로고    scopus 로고
    • Ser9Gly polymorphism of the DRD3 gene is associated with worse premorbid social functioning and an earlier age of onset in female but not male schizophrenic patients
    • Godlewska BR, Olajossy-Hilkesberger L, Limon J, Landowski J. 2010. Ser9Gly polymorphism of the DRD3 gene is associated with worse premorbid social functioning and an earlier age of onset in female but not male schizophrenic patients. Psychiatry Res 177(1-2):266-267.
    • (2010) Psychiatry Res , vol.177 , Issue.1-2 , pp. 266-267
    • Godlewska, B.R.1    Olajossy-Hilkesberger, L.2    Limon, J.3    Landowski, J.4
  • 44
    • 0003318460 scopus 로고
    • Gender and the familial transmission of schizophrenia
    • Seeman MV, Washington, DC: American Psychiatric Press
    • Goldstein JM. 1995. Gender and the familial transmission of schizophrenia. In: Seeman MV, editor. Gender and psychopathology. Washington, DC: American Psychiatric Press. pp 201-226.
    • (1995) Gender and psychopathology , pp. 201-226
    • Goldstein, J.M.1
  • 45
    • 0023904861 scopus 로고
    • Gender and the expression of schizophrenia
    • Goldstein JM, Link BG. 1988. Gender and the expression of schizophrenia. J Psychiatr Res 22:141-155.
    • (1988) J Psychiatr Res , vol.22 , pp. 141-155
    • Goldstein, J.M.1    Link, B.G.2
  • 48
    • 0027386177 scopus 로고
    • The role of gender in understanding the familial transmission of schizoaffective disorder
    • Goldstein JM, Faraone SV, Chen WJ, Tsuang MT. 1993. The role of gender in understanding the familial transmission of schizoaffective disorder. Br J Psychiatry 163:763-768.
    • (1993) Br J Psychiatry , vol.163 , pp. 763-768
    • Goldstein, J.M.1    Faraone, S.V.2    Chen, W.J.3    Tsuang, M.T.4
  • 49
    • 0029645985 scopus 로고
    • Genetic heterogeneity may in part explain sex differences in the familial risk for schizophrenia
    • Goldstein JM, Faraone SV, Chen WJ, Tsuang MT. 1995. Genetic heterogeneity may in part explain sex differences in the familial risk for schizophrenia. Biol Psychiatry 38:808-813.
    • (1995) Biol Psychiatry , vol.38 , pp. 808-813
    • Goldstein, J.M.1    Faraone, S.V.2    Chen, W.J.3    Tsuang, M.T.4
  • 56
    • 0028113510 scopus 로고
    • Schizophrenia epigenesis: Past, present, and future
    • Gottesman II. 1994. Schizophrenia epigenesis: Past, present, and future. Acta Psychiatr Scand 90:26-33.
    • (1994) Acta Psychiatr Scand , vol.90 , pp. 26-33
    • Gottesman, I.I.1
  • 62
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium, Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P. 2009. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460(7256):748-752.
    • (2009) Nature , vol.460 , Issue.7256 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6    Sklar, P.7
  • 64
    • 0001505296 scopus 로고
    • The genetics of schizophrenia: An overview
    • Tsuang MT, Simpson JC, Amsterdam: Elsevier
    • Kendler KS. 1988. The genetics of schizophrenia: An overview. In: Tsuang MT, Simpson JC, editors. Handbook of schizophrenia: Nosology, epidemiology and genetics. Amsterdam: Elsevier. pp 437-462.
    • (1988) Handbook of schizophrenia: Nosology, epidemiology and genetics , pp. 437-462
    • Kendler, K.S.1
  • 65
    • 0036207456 scopus 로고    scopus 로고
    • A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome
    • Klauck S, Lindsay SJ, Beyer K, Splitt M, Burn J, Poustka A. 2002. A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome. Am J Hum Genet 70:1034-1037.
    • (2002) Am J Hum Genet , vol.70 , pp. 1034-1037
    • Klauck, S.1    Lindsay, S.J.2    Beyer, K.3    Splitt, M.4    Burn, J.5    Poustka, A.6
  • 67
    • 0011369965 scopus 로고
    • An epidemiological-clinical twin study on schizophrenia
    • Rosenthal D, Kesy S, Oxford: Pergamon Press
    • Kringlen E. 1968. An epidemiological-clinical twin study on schizophrenia. In: Rosenthal D, Kesy S, editors. The transmission of schizophrenia. Oxford: Pergamon Press. pp 49-63.
    • (1968) The transmission of schizophrenia , pp. 49-63
    • Kringlen, E.1
  • 70
    • 0018339671 scopus 로고
    • Sex differences in schizophrenia: A commentary
    • Lewine RR. 1979. Sex differences in schizophrenia: A commentary. Schizophr Bull 5(1):4-7.
    • (1979) Schizophr Bull , vol.5 , Issue.1 , pp. 4-7
    • Lewine, R.R.1
  • 71
    • 0021365709 scopus 로고
    • Effect of diagnostic criteria on the ratio of male to female schizophrenic patients
    • Lewine R, Burbach D, Meltzer HY. 1984. Effect of diagnostic criteria on the ratio of male to female schizophrenic patients. Am J Psychiatry 141(1):84-87.
    • (1984) Am J Psychiatry , vol.141 , Issue.1 , pp. 84-87
    • Lewine, R.1    Burbach, D.2    Meltzer, H.Y.3
  • 72
    • 52449136362 scopus 로고
    • Vorlaufiger bericht uber psychiatrische serienuntersuchungen an zwillingen [First report of a series of psychiatric twins]
    • Luxenberger H. 1928. Vorlaufiger bericht uber psychiatrische serienuntersuchungen an zwillingen [First report of a series of psychiatric twins]. Z Gesamte Neurol Psy [J Neurol Psychiatry] 116:297-326.
    • (1928) Z Gesamte Neurol Psy [J Neurol Psychiatry] , vol.116 , pp. 297-326
    • Luxenberger, H.1
  • 73
    • 84885825653 scopus 로고
    • Die manifestationswahrscheinlichkeit der schizophrenie im lichte der zwillingsforschung [The expression of schizophrenia in twins]
    • Luxenberger H. 1934. Die manifestationswahrscheinlichkeit der schizophrenie im lichte der zwillingsforschung [The expression of schizophrenia in twins]. Z Psych Hyg [J Psychiatr Hyg] 7:174-184.
    • (1934) Z Psych Hyg [J Psychiatr Hyg] , vol.7 , pp. 174-184
    • Luxenberger, H.1
  • 76
    • 78649505227 scopus 로고    scopus 로고
    • Meta-analysis of sex-specific genome-wide association studies
    • Magi R, Lindgren CM, Morris AP. 2010. Meta-analysis of sex-specific genome-wide association studies. Genet Epidemiol 34(8):846-853.
    • (2010) Genet Epidemiol , vol.34 , Issue.8 , pp. 846-853
    • Magi, R.1    Lindgren, C.M.2    Morris, A.P.3
  • 77
    • 84858434210 scopus 로고    scopus 로고
    • CNVs: Harbingers of a rare variant revolution in psychiatric genetics
    • Malhotra D, Sebat J. 2012. CNVs: Harbingers of a rare variant revolution in psychiatric genetics. Cell 148(6):1223-1241.
    • (2012) Cell , vol.148 , Issue.6 , pp. 1223-1241
    • Malhotra, D.1    Sebat, J.2
  • 78
    • 84860791082 scopus 로고    scopus 로고
    • Why schizophrenia genetics needs epigenetics: A review
    • Maric NP, Svrakic DM. 2012. Why schizophrenia genetics needs epigenetics: A review. Psychiatr Danub 24(1):2-18.
    • (2012) Psychiatr Danub , vol.24 , Issue.1 , pp. 2-18
    • Maric, N.P.1    Svrakic, D.M.2
  • 80
    • 55249091422 scopus 로고    scopus 로고
    • Schizophrenia: A concise overview of incidence, prevalence, and mortality
    • McGrath J, Saha S, Chant D, Welham J. 2008. Schizophrenia: A concise overview of incidence, prevalence, and mortality. Epidemiol Rev 30(1):67-76.
    • (2008) Epidemiol Rev , vol.30 , Issue.1 , pp. 67-76
    • McGrath, J.1    Saha, S.2    Chant, D.3    Welham, J.4
  • 81
    • 0019142381 scopus 로고
    • Linkage between glucose-6-phosphate dehydrogenase deficiency and manic-depressive psychosis
    • Mendlewicz J, Linkowski P, Wilmotte J. 1980. Linkage between glucose-6-phosphate dehydrogenase deficiency and manic-depressive psychosis. Br J Psychiatry 137:337-342.
    • (1980) Br J Psychiatry , vol.137 , pp. 337-342
    • Mendlewicz, J.1    Linkowski, P.2    Wilmotte, J.3
  • 83
    • 0028786445 scopus 로고
    • Potential linkage disequilibrium between schizophrenia and locus D22S278 on the long arm of chromosome 22
    • Moises HW, Yang L, Li T, Havsteen B, Fimmers R, Baur MP, Liu X, Gottesman II. 1995b. Potential linkage disequilibrium between schizophrenia and locus D22S278 on the long arm of chromosome 22. Am J Med Genet 60(5):465-467.
    • (1995) Am J Med Genet , vol.60 , Issue.5 , pp. 465-467
    • Moises, H.W.1    Yang, L.2    Li, T.3    Havsteen, B.4    Fimmers, R.5    Baur, M.P.6    Liu, X.7    Gottesman, I.I.8
  • 85
    • 84965222510 scopus 로고
    • The Huxley Lecture on Hereditary Aspects of Nervous and Mental Diseases
    • Mott FW. 1910. The Huxley Lecture on Hereditary Aspects of Nervous and Mental Diseases. Br Med J 2(2597):1013-1020.
    • (1910) Br Med J , vol.2 , Issue.2597 , pp. 1013-1020
    • Mott, F.W.1
  • 86
    • 84871267120 scopus 로고    scopus 로고
    • The emerging spectrum of allelic variation in schizophrenia: Current evidence and strategies for the identification and functional characterization of common and rare variants
    • Mowry BJ, Gratten J. 2013. The emerging spectrum of allelic variation in schizophrenia: Current evidence and strategies for the identification and functional characterization of common and rare variants. Mol Psychiatry 18(1):38-52.
    • (2013) Mol Psychiatry , vol.18 , Issue.1 , pp. 38-52
    • Mowry, B.J.1    Gratten, J.2
  • 89
    • 0024389626 scopus 로고
    • Gender differences in the etiology and symptoms of schizophrenia: Genetic versus brain injury factor
    • Nasrallah HA, Wilcox JA. 1989. Gender differences in the etiology and symptoms of schizophrenia: Genetic versus brain injury factor. Ann Clin Psychiatry 1(1):51-53.
    • (1989) Ann Clin Psychiatry , vol.1 , Issue.1 , pp. 51-53
    • Nasrallah, H.A.1    Wilcox, J.A.2
  • 91
    • 0023707747 scopus 로고
    • Prevalence of familiality, obstetric complications, and structural brain damage in schizophrenic patients
    • Nimgaonkar VL, Wessely S, Murray RM. 1988. Prevalence of familiality, obstetric complications, and structural brain damage in schizophrenic patients. Br J Psychiatry 153:191-197.
    • (1988) Br J Psychiatry , vol.153 , pp. 191-197
    • Nimgaonkar, V.L.1    Wessely, S.2    Murray, R.M.3
  • 93
    • 77954513019 scopus 로고    scopus 로고
    • Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia
    • Owen MJ, Craddock N, O'Donovan MC. 2010. Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia. Arch Gen Psychiatry 67(7):667-673.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.7 , pp. 667-673
    • Owen, M.J.1    Craddock, N.2    O'Donovan, M.C.3
  • 94
    • 0033580988 scopus 로고    scopus 로고
    • Sixth world congress of psychiatric genetics X chromosome workshop
    • Paterson AD. 1999. Sixth world congress of psychiatric genetics X chromosome workshop. Am J Med Genet 88(3):279-286.
    • (1999) Am J Med Genet , vol.88 , Issue.3 , pp. 279-286
    • Paterson, A.D.1
  • 95
    • 0025733622 scopus 로고
    • Survey of cases of familial mental illness
    • Penrose LS. 1945. Survey of cases of familial mental illness. Eur Arch Psychiatry Clin Neurosci 240(6):315-324.
    • (1945) Eur Arch Psychiatry Clin Neurosci , vol.240 , Issue.6 , pp. 315-324
    • Penrose, L.S.1
  • 97
    • 34548700129 scopus 로고    scopus 로고
    • The association of the HOPA (12bp) polymorphism with schizophrenia in the NIMH Genetics Initiative for Schizophrenia sample
    • Philibert RA, Bohle P, Secrest D, Deaderick J, Sandhu HK, Crowe RR, Black DW. 2007. The association of the HOPA (12bp) polymorphism with schizophrenia in the NIMH Genetics Initiative for Schizophrenia sample. Am J Med Genet Part B 144B(6):743-747.
    • (2007) Am J Med Genet Part B , vol.144 B , Issue.6 , pp. 743-747
    • Philibert, R.A.1    Bohle, P.2    Secrest, D.3    Deaderick, J.4    Sandhu, H.K.5    Crowe, R.R.6    Black, D.W.7
  • 102
    • 0026355571 scopus 로고
    • Estimating effects of proband characteristics on familial risk: II. The association between age at onset and familial risk in the Maryland schizophrenia sample
    • Pulver AE, Liang KY. 1991. Estimating effects of proband characteristics on familial risk: II. The association between age at onset and familial risk in the Maryland schizophrenia sample. Genet Epidemiol 8(5):339-350.
    • (1991) Genet Epidemiol , vol.8 , Issue.5 , pp. 339-350
    • Pulver, A.E.1    Liang, K.Y.2
  • 109
    • 0025828430 scopus 로고
    • A note on multiple testing procedures in linkage analysis
    • Risch N. 1991. A note on multiple testing procedures in linkage analysis. Am J Hum Genet 48:1058-1064.
    • (1991) Am J Hum Genet , vol.48 , pp. 1058-1064
    • Risch, N.1
  • 111
    • 0001418839 scopus 로고
    • The etiology of so-called schizophrenic psychoses with special reference to their occurrence in twins
    • Rosanoff AJ, Handy LM, Plesset IR, Brush S. 1934. The etiology of so-called schizophrenic psychoses with special reference to their occurrence in twins. Am J Psychiatry 91(2):247-286.
    • (1934) Am J Psychiatry , vol.91 , Issue.2 , pp. 247-286
    • Rosanoff, A.J.1    Handy, L.M.2    Plesset, I.R.3    Brush, S.4
  • 112
    • 0343727231 scopus 로고
    • Familial concordance by sex with respect to schizophrenia
    • Rosenthal D. 1962. Familial concordance by sex with respect to schizophrenia. Psychol Bull 59(5):401-421.
    • (1962) Psychol Bull , vol.59 , Issue.5 , pp. 401-421
    • Rosenthal, D.1
  • 113
    • 77950804485 scopus 로고    scopus 로고
    • Turner syndrome and schizophrenia: A further hint for the role of the X-chromosome in the pathogenesis of schizophrenic disorders
    • Roser P, Kawohl W. 2008. Turner syndrome and schizophrenia: A further hint for the role of the X-chromosome in the pathogenesis of schizophrenic disorders. World J Biol Psychiatry 11:1-4.
    • (2008) World J Biol Psychiatry , vol.11 , pp. 1-4
    • Roser, P.1    Kawohl, W.2
  • 114
    • 77950804485 scopus 로고    scopus 로고
    • Turner syndrome and schizophrenia: A further hint for the role of the X-chromosome in the pathogenesis of schizophrenic disorders
    • Roser P, Kawohl W. 2010. Turner syndrome and schizophrenia: A further hint for the role of the X-chromosome in the pathogenesis of schizophrenic disorders. World J Biol Psychiatry 11(2 Pt 2):239-242.
    • (2010) World J Biol Psychiatry , vol.11 , Issue.2 PART 2 , pp. 239-242
    • Roser, P.1    Kawohl, W.2
  • 116
    • 0018369154 scopus 로고
    • Sex differences in concordance rates for schizophrenia in twins
    • Samuels L. 1979. Sex differences in concordance rates for schizophrenia in twins. Schizophr Bull 5(1):8-10.
    • (1979) Schizophr Bull , vol.5 , Issue.1 , pp. 8-10
    • Samuels, L.1
  • 118
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. 2011. Genome-wide association study identifies five new schizophrenia loci. Nat Genet 43(10):969-976.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 969-976
  • 119
    • 2642611497 scopus 로고
    • Zur erbpathologie der schizophrenie [On inherited pathology of schizophrenia]
    • Schultz B. 1932. Zur erbpathologie der schizophrenie [On inherited pathology of schizophrenia]. Z Gesamte Neurol Psychiatr [J Neurol Psychiatry] 143:175-293.
    • (1932) Z Gesamte Neurol Psychiatr [J Neurol Psychiatry] , vol.143 , pp. 175-293
    • Schultz, B.1
  • 126
    • 84941018335 scopus 로고
    • The monogenic theory of schizophrenia
    • Slater E. 1958. The monogenic theory of schizophrenia. Acta Genet Stat Med 8:50-56.
    • (1958) Acta Genet Stat Med , vol.8 , pp. 50-56
    • Slater, E.1
  • 131
    • 0023219530 scopus 로고
    • Changes in the incidence of schizophrenia
    • Stromgren E. 1987. Changes in the incidence of schizophrenia? Br J Psychiatry 150:1-7.
    • (1987) Br J Psychiatry , vol.150 , pp. 1-7
    • Stromgren, E.1
  • 133
    • 24944497668 scopus 로고    scopus 로고
    • Gender-specific association of insertion/deletion polymorphisms in the nogo gene and chronic schizophrenia
    • Tan EC, Chong SA, Wang H, Chew-Ping Lim E, Teo YY. 2005. Gender-specific association of insertion/deletion polymorphisms in the nogo gene and chronic schizophrenia. Brain Res Mol Brain Res 139(2):212-216.
    • (2005) Brain Res Mol Brain Res , vol.139 , Issue.2 , pp. 212-216
    • Tan, E.C.1    Chong, S.A.2    Wang, H.3    Chew-Ping Lim, E.4    Teo, Y.Y.5
  • 135
    • 0014061579 scopus 로고
    • A study of pairs of siblings both hospitalized for mental disorder
    • Tsuang MT. 1967. A study of pairs of siblings both hospitalized for mental disorder. Br J Psychiatry 13:283-300.
    • (1967) Br J Psychiatry , vol.13 , pp. 283-300
    • Tsuang, M.T.1
  • 139
    • 33750589017 scopus 로고    scopus 로고
    • Klinefelter's syndrome (karyotype 47,XXY) and schizophrenia-spectrum pathology
    • van Rijn S, Aleman A, Swaab H, Kahn R. 2006. Klinefelter's syndrome (karyotype 47, XXY) and schizophrenia-spectrum pathology. Br J Psychiatry 189:459-460.
    • (2006) Br J Psychiatry , vol.189 , pp. 459-460
    • van Rijn, S.1    Aleman, A.2    Swaab, H.3    Kahn, R.4
  • 140
    • 0018697489 scopus 로고
    • Fertility and sibship size in a psychiatric patient population
    • Vogel HP. 1979. Fertility and sibship size in a psychiatric patient population. Acta Psychiatr Scand 60:483-503.
    • (1979) Acta Psychiatr Scand , vol.60 , pp. 483-503
    • Vogel, H.P.1
  • 142
    • 80051559269 scopus 로고    scopus 로고
    • Genome-wide association analysis of age at onset in schizophrenia in a European-American sample
    • Wang KS, Liu X, Zhang Q, Aragam N, Pan Y. 2011. Genome-wide association analysis of age at onset in schizophrenia in a European-American sample. Am J Med Genet Part B 156B(6):671-680.
    • (2011) Am J Med Genet Part B , vol.156 B , Issue.6 , pp. 671-680
    • Wang, K.S.1    Liu, X.2    Zhang, Q.3    Aragam, N.4    Pan, Y.5
  • 143
    • 33646180128 scopus 로고    scopus 로고
    • A further study of a possible locus for schizophrenia on the X chromosome
    • Wei J, Hemmings G. 2006. A further study of a possible locus for schizophrenia on the X chromosome. Biochem Biophys Res Commun 344:1241-1245.
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 1241-1245
    • Wei, J.1    Hemmings, G.2
  • 150
    • 0023824742 scopus 로고
    • Schizophrenia, just the facts. What do we know, how well do we know it
    • Wyatt RJ, Alexander RC, Egan MF, Kirch DG. 1988. Schizophrenia, just the facts. What do we know, how well do we know it? Schizophr Res 1:3-18.
    • (1988) Schizophr Res , vol.1 , pp. 3-18
    • Wyatt, R.J.1    Alexander, R.C.2    Egan, M.F.3    Kirch, D.G.4
  • 151
    • 80255132087 scopus 로고    scopus 로고
    • Association between schizophrenia and single nucleotide polymorphisms in lipoprotein lipase gene in a Han Chinese population
    • Xie C, Wang ZC, Liu XF, Wang L, Yang MS. 2011. Association between schizophrenia and single nucleotide polymorphisms in lipoprotein lipase gene in a Han Chinese population. Psychiatr Genet 21(6):307-314.
    • (2011) Psychiatr Genet , vol.21 , Issue.6 , pp. 307-314
    • Xie, C.1    Wang, Z.C.2    Liu, X.F.3    Wang, L.4    Yang, M.S.5


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