메뉴 건너뛰기




Volumn 73, Issue 6, 2003, Pages 1355-1367

A Systematic Genomewide Linkage Study in 353 Sib Pairs with Schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 10Q; CHROMOSOME 17P; CHROMOSOME 17Q; CHROMOSOME 22Q; CLINICAL TRIAL; GENE MAPPING; GENETIC LINKAGE; HUMAN; HUMAN GENOME; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; MULTICENTER STUDY; PEDIGREE; PRIORITY JOURNAL; SCHIZOPHRENIA; SIBLING; SIMULATION;

EID: 9144220855     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/380206     Document Type: Article
Times cited : (107)

References (70)
  • 2
    • 0036258079 scopus 로고    scopus 로고
    • Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia
    • Badner JA, Gershon ES (2002) Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 7:405-411
    • (2002) Mol Psychiatry , vol.7 , pp. 405-411
    • Badner, J.A.1    Gershon, E.S.2
  • 4
    • 0030881661 scopus 로고    scopus 로고
    • Accurate inference of relationships in sib-pair linkage studies
    • Boehnke M, Cox NJ (1997) Accurate inference of relationships in sib-pair linkage studies. Am J Hum Genet 61:423-429
    • (1997) Am J Hum Genet , vol.61 , pp. 423-429
    • Boehnke, M.1    Cox, N.J.2
  • 6
    • 0035057742 scopus 로고    scopus 로고
    • Searching for schizophrenia genes
    • Bray NJ, Owen MJ (2001) Searching for schizophrenia genes. Trends Mol Med 7:169-174
    • (2001) Trends Mol Med , vol.7 , pp. 169-174
    • Bray, N.J.1    Owen, M.J.2
  • 7
    • 0032231347 scopus 로고    scopus 로고
    • Estimation of pairwise relationships in the presence of genotyping errors
    • Broman KW, Weber JL (1998) Estimation of pairwise relationships in the presence of genotyping errors. Am J Hum Genet 63:1563-1564
    • (1998) Am J Hum Genet , vol.63 , pp. 1563-1564
    • Broman, K.W.1    Weber, J.L.2
  • 8
    • 0034724924 scopus 로고    scopus 로고
    • Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22
    • Brzustowicz LM, Hodgkinson KA, Chow EW, Honer WG, Bassett AS (2000) Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22. Science 288:678-682
    • (2000) Science , vol.288 , pp. 678-682
    • Brzustowicz, L.M.1    Hodgkinson, K.A.2    Chow, E.W.3    Honer, W.G.4    Bassett, A.S.5
  • 13
    • 0036373344 scopus 로고    scopus 로고
    • A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22-21, 4p16, 6q14-22, 10q26 and 16p13.3
    • Ewald H, Flint T, Kruse TA, Mors O (2002) A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22-21, 4p16, 6q14-22, 10q26 and 16p13.3. Mol Psychiatry 7:734-744
    • (2002) Mol Psychiatry , vol.7 , pp. 734-744
    • Ewald, H.1    Flint, T.2    Kruse, T.A.3    Mors, O.4
  • 14
    • 0030927756 scopus 로고    scopus 로고
    • Relationship estimation in affected sib-pair analysis of late-onset diseases
    • Göring HH, Ott J (1997) Relationship estimation in affected sib-pair analysis of late-onset diseases. Eur J Hum Genet 5:69-77
    • (1997) Eur J Hum Genet , vol.5 , pp. 69-77
    • Göring, H.H.1    Ott, J.2
  • 15
    • 0035209177 scopus 로고    scopus 로고
    • Large upward bias in estimation of locus-specific effects from genomewide scans
    • Göring HH, Terwilliger JD, Blangero J (2001) Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet 69:1357-1369
    • (2001) Am J Hum Genet , vol.69 , pp. 1357-1369
    • Göring, H.H.1    Terwilliger, J.D.2    Blangero, J.3
  • 17
    • 0035089756 scopus 로고    scopus 로고
    • Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23
    • Gurling HM, Kalsi G, Brynjolfson J, Sigmundsson T, Sherrington R, Mankoo BS. Read T, Murphy P, Blaveri E, McQuillin A, Petursson H, Curtis D (2001) Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. Am J Hum Genet 68:661-673
    • (2001) Am J Hum Genet , vol.68 , pp. 661-673
    • Gurling, H.M.1    Kalsi, G.2    Brynjolfson, J.3    Sigmundsson, T.4    Sherrington, R.5    Mankoo, B.S.6    Read, T.7    Murphy, P.8    Blaveri, E.9    McQuillin, A.10    Petursson, H.11    Curtis, D.12
  • 18
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison PJ (1999) The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122:593-624
    • (1999) Brain , vol.122 , pp. 593-624
    • Harrison, P.J.1
  • 19
    • 0028832203 scopus 로고
    • Efficiency of typing unaffected relatives in an affected-sib-pair linkage study with single-locus and multiple tightly linked markers
    • Holmans P, Clayton D (1995) Efficiency of typing unaffected relatives in an affected-sib-pair linkage study with single-locus and multiple tightly linked markers. Am J Hum Genet 57:1221-1232
    • (1995) Am J Hum Genet , vol.57 , pp. 1221-1232
    • Holmans, P.1    Clayton, D.2
  • 23
    • 0029046177 scopus 로고
    • Complete multipoint sib pair analysis of qualitative and quantitative traits
    • Kruglyak L, Lander ES (1995) Complete multipoint sib pair analysis of qualitative and quantitative traits. Am J Hum Genet 57:439-454
    • (1995) Am J Hum Genet , vol.57 , pp. 439-454
    • Kruglyak, L.1    Lander, E.S.2
  • 24
    • 0000803318 scopus 로고
    • Construction of multilocus genetic linkage maps in humans
    • Lander ES, Green P (1987) Construction of multilocus genetic linkage maps in humans. Proc Natl Acad Sci USA 84:2363-2367
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2363-2367
    • Lander, E.S.1    Green, P.2
  • 25
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits - Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L (1995) Genetic dissection of complex traits - guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 28
    • 0038003197 scopus 로고    scopus 로고
    • Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis
    • Levinson DF, Levinson MD, Segurado R, Lewis CM (2003) Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: methods and power analysis. Am J Hum Genet 73:17-33
    • (2003) Am J Hum Genet , vol.73 , pp. 17-33
    • Levinson, D.F.1    Levinson, M.D.2    Segurado, R.3    Lewis, C.M.4
  • 33
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177-182
    • (2003) Nat Genet , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 36
    • 0342963269 scopus 로고    scopus 로고
    • Further evidence of a susceptibility gene for schizophrenia in 6p22-p24: A contribution from the eastern Quebec population
    • Maziade M, Bissonnette L, Rouillard E, Roy MA, Merette C (1997) Further evidence of a susceptibility gene for schizophrenia in 6p22-p24: A contribution from the eastern Quebec population. Am J Med Genet 74:666-667
    • (1997) Am J Med Genet , vol.74 , pp. 666-667
    • Maziade, M.1    Bissonnette, L.2    Rouillard, E.3    Roy, M.A.4    Merette, C.5
  • 37
    • 0023894061 scopus 로고
    • A single dominant gene still cannot account for the transmission of schizophrenia
    • McGue M, Gottesman II (1988) A single dominant gene still cannot account for the transmission of schizophrenia. Arch Gen Psychiatry 45:641-647
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 641-647
    • McGue, M.1    Gottesman, I.I.2
  • 38
    • 0026410654 scopus 로고
    • A polydiagnostic application of operational criteria in studies of psychotic illness: Development and reliability of the OPCRIT system
    • McGuffin P, Farmer A, Harvey I (1991) A polydiagnostic application of operational criteria in studies of psychotic illness: development and reliability of the OPCRIT system. Arch Gen Psychiatry 48:764-770
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 764-770
    • McGuffin, P.1    Farmer, A.2    Harvey, I.3
  • 39
    • 0033912689 scopus 로고    scopus 로고
    • Statistical tests for detection of misspecified relationships by use of genome-screen data
    • McPeek MS, Sun L (2000) Statistical tests for detection of misspecified relationships by use of genome-screen data. Am J Hum Genet 66:1076-1094
    • (2000) Am J Hum Genet , vol.66 , pp. 1076-1094
    • McPeek, M.S.1    Sun, L.2
  • 42
    • 0032882849 scopus 로고    scopus 로고
    • High rates of schizophrenia in adults with velo-cardio-facial syndrome
    • Murphy KC, Jones LA, Owen MJ (1999) High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch Gen Psychiatry 56:940-945
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 940-945
    • Murphy, K.C.1    Jones, L.A.2    Owen, M.J.3
  • 44
    • 0024275813 scopus 로고
    • Is schizophrenia a neurodevelopmental disorder?
    • Murray RM, Lewis SW (1988) Is schizophrenia a neurodevelopmental disorder? Br Med J 296:63
    • (1988) Br Med J , vol.296 , pp. 63
    • Murray, R.M.1    Lewis, S.W.2
  • 46
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilities in linkage analysis
    • O'Connell JR, Weeks DE (1998) PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63:259-266
    • (1998) Am J Hum Genet , vol.63 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 49
    • 0012150654 scopus 로고    scopus 로고
    • Schizophrenia
    • McGuffin P, Owen MJ, Gottesman II (eds) Oxford University Press, Oxford
    • Owen MJ, O'Donovan MC, Gottesman II (2002) Schizophrenia. In: McGuffin P, Owen MJ, Gottesman II (eds) Psychiatric genetics and genomics. Oxford University Press, Oxford, pp 247-266
    • (2002) Psychiatric Genetics and Genomics , pp. 247-266
    • Owen, M.J.1    O'Donovan, M.C.2    Gottesman, I.I.3
  • 50
    • 0029853761 scopus 로고    scopus 로고
    • Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: Does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder?
    • Papolos DF, Faedda GI, Veit S, Goldberg RB, Morrow B, Kucherlapati R, Shprintzen RJ (1996) Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder? Am J Psychiatry 153:1541-1547
    • (1996) Am J Psychiatry , vol.153 , pp. 1541-1547
    • Papolos, D.F.1    Faedda, G.I.2    Veit, S.3    Goldberg, R.B.4    Morrow, B.5    Kucherlapati, R.6    Shprintzen, R.J.7
  • 52
    • 0025008677 scopus 로고
    • Linkage strategies for genetically complex traits 2. The power of affected relative pairs
    • Risch N (1990) Linkage strategies for genetically complex traits 2. The power of affected relative pairs. Am J Hum Genet 46:229-241
    • (1990) Am J Hum Genet , vol.46 , pp. 229-241
    • Risch, N.1
  • 53
    • 0029845435 scopus 로고    scopus 로고
    • Additional support for schizophrenia linkage on chromosomes 6 and 8: A multicenter study
    • Schizophrenia Linkage Collaborative Group for Chromosomes 3, 6, and 8 (1996) Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study. Am J Med Genet 67:580-594
    • (1996) Am J Med Genet , vol.67 , pp. 580-594
  • 62
    • 0028820161 scopus 로고
    • A potential vulnerability locus for schizophrenia on chromosome 6p24-22 - Evidence for genetic-heterogeneity
    • Straub RE, Maclean CJ, ONeill FA, Burke J, Murphy B, Duke F (1995) A potential vulnerability locus for schizophrenia on chromosome 6p24-22 - evidence for genetic-heterogeneity. Nat Genet 11:287-293
    • (1995) Nat Genet , vol.11 , pp. 287-293
    • Straub, R.E.1    Maclean, C.J.2    ONeill, F.A.3    Burke, J.4    Murphy, B.5    Duke, F.6
  • 63
    • 0002710362 scopus 로고
    • Problems of replicating linkage claims in psychiatry
    • Gershon ES, Cloninger CR (eds) American Psychiatric Press, Washington, DC
    • Suarez BK, Hampe CL, Van Eerdewegh P (1994) Problems of replicating linkage claims in psychiatry. In: Gershon ES, Cloninger CR (eds) Genetic approaches to mental disorders. American Psychiatric Press, Washington, DC, pp 23-46
    • (1994) Genetic Approaches to Mental Disorders , pp. 23-46
    • Suarez, B.K.1    Hampe, C.L.2    Van Eerdewegh, P.3
  • 64
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • Weinberger DR (1987) Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 44:660-669
    • (1987) Arch Gen Psychiatry , vol.44 , pp. 660-669
    • Weinberger, D.R.1
  • 66
    • 0036224396 scopus 로고    scopus 로고
    • Genome scans and microarrays: Converging on genes for schizophrenia?
    • reviews
    • Williams NM, O'Donovan MC, Owen MJ (2002) Genome scans and microarrays: converging on genes for schizophrenia? Genome Biol 3:reviews1011.1-1011.5
    • (2002) Genome Biol , vol.3 , pp. 10111-10115
    • Williams, N.M.1    O'Donovan, M.C.2    Owen, M.J.3
  • 68
    • 0032858459 scopus 로고    scopus 로고
    • A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs
    • Williams NM, Rees MI, Holmans P, Norton N, Cardno AG, Jones LA (1999) A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs. Hum Mol Genet 8:1729-1739
    • (1999) Hum Mol Genet , vol.8 , pp. 1729-1739
    • Williams, N.M.1    Rees, M.I.2    Holmans, P.3    Norton, N.4    Cardno, A.G.5    Jones, L.A.6
  • 69
    • 0025439099 scopus 로고
    • SCAN: Schedules for the clinical assessment in neuropsychiatry
    • Wing JK, Babor T, Brugha T (1990) SCAN: schedules for the clinical assessment in neuropsychiatry. Arch Gen Psychiatry 47:589-593
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 589-593
    • Wing, J.K.1    Babor, T.2    Brugha, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.