Establishment of a new in vitro test method for evaluation of eye irritancy using a reconstructed human corneal epithelial model, LabCyte CORNEA-MODEL

Toxicology in Vitro

Volumn 27, Issue 8, 2013, Pages 2184-2192

  Katoh, Masakazu ^a   Hamajima, Fumiyasu ^a   Ogasawara, Takahiro ^a   Hata, Ken ichiro ^a  

^a Japan Tissue Engineering Co Ltd   (Japan)

Author keywords

Alternative methods; Eye irritation; In vitro; LabCyte CORNEA MODEL; Ocular; Reconstructed human corneal epithelium

Indexed keywords

1 NAPHTHYLACETIC ACID; 2 PROPANOL; ACETIC ACID; ACETONE; BENZALKONIUM CHLORIDE; BENZYL ALCOHOL; BUTANOL; CHLORHEXIDINE GLUCONATE; CYCLOHEXANOL; DIISOPROPANOLAMINE; DODECYL SULFATE SODIUM; DOMIPHEN BROMIDE; GLYCEROL; GLYCOLIC ACID; HEXANOL; LACTIC ACID; LAURIC ACID; MACROGOL 400; MYRISTIC ACID ISOPROPYL ESTER; OCTANOL; POLYSORBATE; POLYSORBATE 20; PROPYLENE GLYCOL; ROSE BENGAL; SILICIC ACID; SODIUM CHLORIDE; SODIUM HYDROXIDE; TOLUENE; XYLENE;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; EYE IRRITATION; EYE TOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LONG TERM EXPOSURE; PREDICTION; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; QUALITY CONTROL; TOXICITY TESTING; VALIDATION PROCESS;

ALTERNATIVE METHODS; EYE IRRITATION; IN VITRO; LABCYTE CORNEA-MODEL; OCULAR; RECONSTRUCTED HUMAN CORNEAL EPITHELIUM;

ANIMAL TESTING ALTERNATIVES; CELL SURVIVAL; EPITHELIUM, CORNEAL; HUMANS; IRRITANTS; REPRODUCIBILITY OF RESULTS; TOXICITY TESTS, ACUTE;

EID: 84885773067     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.08.008     Document Type: Article

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