In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic™ HCE model: Application to 435 substances from consumer products industry

Toxicology in Vitro

Volumn 24, Issue 2, 2010, Pages 523-537

  Cotovio, José ^a   Grandidier, Marie Hélène ^a   Lelièvre, Damien ^a   Bremond, Christelle ^b   Amsellem, Carolle ^b   Maloug, Saber ^a   Ovigne, Jean Marc ^a   Loisel Joubert, Sophie ^a   Lee, Aline Van Der ^a   Minondo, Anne Marie ^a   Capallere, Christophe ^c   Bertino, Béatrice ^c   Alépée, Nathalie ^a   Tinois Tessonneaud, Estelle ^b   de Fraissinette, Anne De Brugerolle ^c   Meunier, Jean Roch ^a   Leclaire, Jacques ^a  

^a L ORÉAL RECHERCHE   (France)

^b Episkin SNC   (France)

^c SkinEthic Laboratories   (France)

Author keywords

3 D model; Eye irritancy; In vitro; Ocular; SkinEthic HCE; Validation

Indexed keywords

BETAINE; CETOSTEARYLIC ALCOHOL; CINNAMIC ACID; CITRIC ACID; COSMETIC; DIMETICONE; DODECYLSULFATE AMMONIUM; DYE; FATTY ACID DERIVATIVE; FILLER; GLUCONATE ZINC; GLYCEROL; GLYCEROL STEARATE; HYDROGENATED CASTOR OIL; HYDROXYETHYLCELLULOSE; MINERAL OIL; POLIDOCANOL; POLYURETHAN; PRESERVATIVE; PROPYLENE GLYCOL; SALICYLIC ACID; SILICONE; SOLVENT; SORBATE POTASSIUM; SURFACTANT;

ACCURACY; ARTICLE; CORNEA EPITHELIUM; COSMETIC INDUSTRY; DISEASE MODEL; EUROPEAN UNION; EYE IRRITATION; IN VITRO STUDY; INCUBATION TIME; MEDICAL ASSESSMENT; PREDICTION; RELIABILITY; SENSITIVITY AND SPECIFICITY;

ACUTE TOXICITY TESTS; ANIMAL TESTING ALTERNATIVES; COSMETICS; EPITHELIUM, CORNEAL; HUMANS; IRRITANTS; PREDICTIVE VALUE OF TESTS;

ANIMALIA;

EID: 76749147859     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.11.010     Document Type: Article

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