메뉴 건너뛰기




Volumn 51, Issue 11, 2013, Pages 1347-1354

Polydatin: A review of pharmacology and pharmacokinetics

Author keywords

Cardiovascular effect; Immune regulation; Nerve protection; Plant

Indexed keywords

PICEID; RESVERATROL;

EID: 84885670554     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2013.792849     Document Type: Review
Times cited : (210)

References (95)
  • 1
    • 67649833785 scopus 로고    scopus 로고
    • G-Quadruplex nucleic acids as therapeutic targets
    • Balasubramanian S, Neidle S.2009). G-Quadruplex nucleic acids as therapeutic targets. Curr Opin Chem Biol 13:345-53
    • (2009) Curr Opin Chem Biol , vol.13 , pp. 345-353
    • Balasubramanian, S.1    Neidle, S.2
  • 2
    • 70449527578 scopus 로고    scopus 로고
    • Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci
    • Ban SH, Kwona YR, Pandit S, et al.2010). Effects of a bio-assay guided fraction from Polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci. Fitoterapia 81:30-4
    • (2010) Fitoterapia , vol.81 , pp. 30-34
    • Ban, S.H.1    Kwona, Y.R.2    Pandit, S.3
  • 3
    • 84906995030 scopus 로고    scopus 로고
    • Effects of polydatin on the biological features of cultured fibroblasts
    • Bian HN, Sun CW, Chen HD, et al.2012). Effects of polydatin on the biological features of cultured fibroblasts. Chin J Tissue Eng Res 16: 6111-15
    • (2012) Chin J Tissue Eng Res , vol.16 , pp. 6111-6115
    • Bian, H.N.1    Sun, C.W.2    Chen, H.D.3
  • 4
    • 0035527491 scopus 로고    scopus 로고
    • Neurotensinand EGF-induced metabolic activation of colon carcinoma cells is diminished by dietary flavonoid cyanidin but not by its glycosides
    • Briviba K, Abrahamse SL, Pool-Zobel BL, et al.2001). Neurotensinand EGF-induced metabolic activation of colon carcinoma cells is diminished by dietary flavonoid cyanidin but not by its glycosides. Nutr Cancer 41:172-9
    • (2001) Nutr Cancer , vol.41 , pp. 172-179
    • Briviba, K.1    Abrahamse, S.L.2    Pool-Zobel, B.L.3
  • 5
    • 84869875563 scopus 로고    scopus 로고
    • Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose- induced urate nephropathic mice
    • Chen L, Lan Z, Lin Q, et al.2013). Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose- induced urate nephropathic mice. Food Chem Toxicol 52:28-35
    • (2013) Food Chem Toxicol , vol.52 , pp. 28-35
    • Chen, L.1    Lan, Z.2    Lin, Q.3
  • 6
    • 84867294242 scopus 로고    scopus 로고
    • Effects of polydatin on thrombosis and interactions of platelets to neutrophils
    • Chen P, Hu XL, Lei WY, et al.2006a). Effects of polydatin on thrombosis and interactions of platelets to neutrophils. J Yunnan Univ (Natural Sci) 28:364-8
    • (2006) J Yunnan Univ (Natural Sci) , vol.28 , pp. 364-368
    • Chen, P.1    Hu, X.L.2    Lei, W.Y.3
  • 7
    • 84878266080 scopus 로고    scopus 로고
    • Investigation of polydatin on antithrombotic effects and plasma levels of TXB2 and 6-keto-PGF1a
    • Chen P, Yang LC, Hu XL, et al.2006b). Investigation of polydatin on antithrombotic effects and plasma levels of TXB2 and 6-keto-PGF1a. Nat Prod Res Dev 18:398-400, 404
    • (2006) Nat Prod Res Dev , vol.18 , Issue.398-400 , pp. 404
    • Chen, P.1    Yang, L.C.2    Hu, X.L.3
  • 8
    • 33748470087 scopus 로고    scopus 로고
    • Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia- reperfusion injury
    • Cheng Y, Zhang HT, Sun L, et al.2006c). Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia- reperfusion injury. Brain Res 1110:193-200
    • (2006) Brain Res , vol.1110 , pp. 193-200
    • Cheng, Y.1    Zhang, H.T.2    Sun, L.3
  • 9
    • 84867400028 scopus 로고    scopus 로고
    • Polydatin modulates Ca2+ handling, excitation-contraction coupling and b-adrenergic signaling in rat ventricular myocytes
    • Deng J, Liu W, Wang Y, et al.2012). Polydatin modulates Ca2+ handling, excitation-contraction coupling and b-adrenergic signaling in rat ventricular myocytes. J Mole Cell Card 53:646-56
    • (2012) J Mole Cell Card , vol.53 , pp. 646-656
    • Deng, J.1    Liu, W.2    Wang, Y.3
  • 10
    • 79952234852 scopus 로고    scopus 로고
    • Inhibition of TNFa- mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3 540- Trimethoxystilbene
    • Deng YH, Alex D, Huang HQ, et al.2011). Inhibition of TNFa- mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,40- Trimethoxystilbene. Phytother Res 25:451-7
    • (2011) Phytother Res , vol.25 , pp. 451-457
    • Deng, Y.H.1    Alex, D.2    Huang, H.Q.3
  • 11
    • 67349165065 scopus 로고    scopus 로고
    • Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamsters
    • Du J, Sun LN, Xing WW, et al.2009). Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamsters. Phytomedicine 16:652-8
    • (2009) Phytomedicine , vol.16 , pp. 652-658
    • Du, J.1    Sun, L.N.2    Xing, W.W.3
  • 12
    • 43049146486 scopus 로고    scopus 로고
    • Antioxidant properties of resveratrol and piceid on lipid peroxidation in micelles and monolamellar liposomes
    • Fabris S, Momo F, Ravagnan G, et al.2008). Antioxidant properties of resveratrol and piceid on lipid peroxidation in micelles and monolamellar liposomes. Biophys Chem 135:76-83
    • (2008) Biophys Chem , vol.135 , pp. 76-83
    • Fabris, S.1    Momo, F.2    Ravagnan, G.3
  • 13
    • 84885597655 scopus 로고    scopus 로고
    • Effects of polydatin on expressions of NFkB and MPO during renal ischemia-reperfusion injury
    • Fei J, Xie K, Tao FS.2009). Effects of polydatin on expressions of NFkB and MPO during renal ischemia-reperfusion injury. J Clin Anesthesiol 25:511-13
    • (2009) J Clin Anesthesiol , vol.25 , pp. 511-513
    • Fei, J.1    Xie, K.2    Tao, F.S.3
  • 14
    • 77956702315 scopus 로고    scopus 로고
    • Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models
    • Gao JP, Chen CX, Gu WL, et al.2010). Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models. Fitoterapia 81:953-60
    • (2010) Fitoterapia , vol.81 , pp. 953-960
    • Gao, J.P.1    Chen, C.X.2    Gu, W.L.3
  • 15
    • 33645060731 scopus 로고    scopus 로고
    • HPLC determination of polydatin in rat biological matrices: Application to pharmacokinetic studies
    • Gao S, Fan G, Hong Z, et al.2006). HPLC determination of polydatin in rat biological matrices: Application to pharmacokinetic studies. J Pharmaceut Biomed 41:240-5
    • (2006) J Pharmaceut Biomed , vol.41 , pp. 240-245
    • Gao, S.1    Fan, G.2    Hong, Z.3
  • 16
    • 34547666877 scopus 로고    scopus 로고
    • Quantitative determination of trans-polydatin, a natural strong antioxidative compound, in rat plasma and cellular environment of a human colon adenocarcinoma cell line for pharmacokinetic studies
    • He H, Zhao Y, Chen X, et al.2007). Quantitative determination of trans-polydatin, a natural strong antioxidative compound, in rat plasma and cellular environment of a human colon adenocarcinoma cell line for pharmacokinetic studies. J Chromatogr B 855:145-51
    • (2007) J Chromatogr B , vol.855 , pp. 145-151
    • He, H.1    Zhao, Y.2    Chen, X.3
  • 17
    • 84867088429 scopus 로고    scopus 로고
    • Polydatin suppresses ultraviolet B-induced cyclooxygenase-2 expression in vitro and in vivo via reduced production of reactive oxygen species
    • He YD, Liu YT, Lin QX, et al.2012). Polydatin suppresses ultraviolet B-induced cyclooxygenase-2 expression in vitro and in vivo via reduced production of reactive oxygen species. Br J Dermatol 167: 941-4
    • (2012) Br J Dermatol , vol.167 , pp. 941-944
    • He, Y.D.1    Liu, Y.T.2    Lin, Q.X.3
  • 18
    • 13244277948 scopus 로고    scopus 로고
    • Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells
    • Henry C, Vitrac X, Decendit A, et al.2005). Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells. J Agric Food Chem 53: 798-803
    • (2005) J Agric Food Chem , vol.53 , pp. 798-803
    • Henry, C.1    Vitrac, X.2    Decendit, A.3
  • 19
    • 33750314574 scopus 로고    scopus 로고
    • Desmoulière A, Girard D, et a.l.
    • Henry-Vitrac C, Desmoulière A, Girard D, et al.2006). Transport, deglycosylation, and metabolism of trans-piceid by small intestinal epithelial cells. Eur J Nutr 45:376-82
    • (2006) Eur J Nutr , vol.45 , pp. 376-382
    • Henry-Vitrac, C.1
  • 20
    • 0031036740 scopus 로고    scopus 로고
    • Bioavailability of flavonoids
    • Hollman PC.1997). Bioavailability of flavonoids. Eur J Clin Nutr 51: S66-9
    • (1997) Eur J Clin Nutr , vol.51
    • Hollman, P.C.1
  • 21
    • 0028793218 scopus 로고
    • Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers
    • Hollman PC, de Vries JH, van Leeuwen SD, et al.1995). Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am J Clin Nutr 62:1276-82
    • (1995) Am J Clin Nutr , vol.62 , pp. 1276-1282
    • Hollman, P.C.1    De Vries, J.H.2    Van Leeuwen, S.D.3
  • 22
    • 0002554364 scopus 로고    scopus 로고
    • Protective effects of polydatin against CCl4-induced injury to primarily cultured rat hepatocytes
    • Huang ZS, Wang ZW, Liu MP, et al.1999). Protective effects of polydatin against CCl4-induced injury to primarily cultured rat hepatocytes. World J Gastroenterol 5:41-4
    • (1999) World J Gastroenterol , vol.5 , pp. 41-44
    • Huang, Z.S.1    Wang, Z.W.2    Liu, M.P.3
  • 23
    • 78449232856 scopus 로고    scopus 로고
    • Inhibition of melanogenesis by piceid isolated from Polygonum cuspidatum
    • Jeong ET, Jin MH, Kim MS, et al.2010). Inhibition of melanogenesis by piceid isolated from Polygonum cuspidatum. Arch Pharm Res 33: 1331-8
    • (2010) Arch Pharm Res , vol.33 , pp. 1331-1338
    • Jeong, E.T.1    Jin, M.H.2    Kim, M.S.3
  • 24
    • 84155166813 scopus 로고    scopus 로고
    • Polydatin modulates inflammation by decreasing NF-kB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood-brain barrier permeability for its neuroprotective effect in pMCAO rat brain
    • Ji H, Zhang X, Du Y, et al.2012). Polydatin modulates inflammation by decreasing NF-kB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood-brain barrier permeability for its neuroprotective effect in pMCAO rat brain. Brain Res Bulletin 87:50-9
    • (2012) Brain Res Bulletin , vol.87 , pp. 50-59
    • Ji, H.1    Zhang, X.2    Du, Y.3
  • 25
    • 84866786718 scopus 로고    scopus 로고
    • The regulative effects of polydatin on toll-like receptor 4 signal transduction pathway in lung ischemia/reperfusion injury in rabbits
    • Jin XF, Xu ZJ, Wang WT, et al.2009). The regulative effects of polydatin on toll-like receptor 4 signal transduction pathway in lung ischemia/reperfusion injury in rabbits. Chin J Appl Physial 25: 41-4
    • (2009) Chin J Appl Physial , vol.25 , pp. 41-44
    • Jin, X.F.1    Xu, Z.J.2    Wang, W.T.3
  • 26
    • 25844520973 scopus 로고    scopus 로고
    • ESHRE guideline for the diagnosis and treatment of endometriosis
    • Kennedy S, Bergqvist A, Chapron C, et al.2005). ESHRE guideline for the diagnosis and treatment of endometriosis. Hum Reprod 20: 2698-704
    • (2005) Hum Reprod , vol.20 , pp. 2698-2704
    • Kennedy, S.1    Bergqvist, A.2    Chapron, C.3
  • 27
    • 0037013315 scopus 로고    scopus 로고
    • Oxyresveratrol and hydroxystilbene compounds. Inhibitory effect on tyrosinase and mechanism of action
    • Kim YM, Yun J, Lee CK, et al.2002). Oxyresveratrol and hydroxystilbene compounds. Inhibitory effect on tyrosinase and mechanism of action. J Biol Chem 227:16340-4
    • (2002) J Biol Chem , vol.227 , pp. 16340-16344
    • Kim, Y.M.1    Yun, J.2    Lee, C.K.3
  • 28
    • 0033761518 scopus 로고    scopus 로고
    • Effects of naturally occurring stilbene glucosides from medicinal plants and wine, on tumour growth and lung metastasis in Lewis lung carcinoma-bearing mice
    • Kimura Y, Okuda H.2000). Effects of naturally occurring stilbene glucosides from medicinal plants and wine, on tumour growth and lung metastasis in Lewis lung carcinoma-bearing mice. J Pharm Pharmacol 52:1287-95
    • (2000) J Pharm Pharmacol , vol.52 , pp. 1287-1295
    • Kimura, Y.1    Okuda, H.2
  • 29
    • 77249090330 scopus 로고    scopus 로고
    • Bioactivity-guided separation of anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum
    • Kwon YR, Son KJ, Pandit S, et al.2010). Bioactivity-guided separation of anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum. Oral Diseases 16:204-9
    • (2010) Oral Diseases , vol.16 , pp. 204-209
    • Kwon, Y.R.1    Son, K.J.2    Pandit, S.3
  • 30
    • 84859432698 scopus 로고    scopus 로고
    • Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation
    • Lanzilli G, Cottarelli A, Nicotera G, et al.2012). Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation. Inflammation 35:240-8
    • (2012) Inflammation , vol.35 , pp. 240-248
    • Lanzilli, G.1    Cottarelli, A.2    Nicotera, G.3
  • 31
    • 77954485188 scopus 로고    scopus 로고
    • Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene
    • Li H, Yuan G.2010). Electrospray ionization mass spectrometry probing of formation and recognition of the G-quadruplex in the proximal promoter of the human vascular endothelial growth factor gene. Rapid Commun Mass Sp 24:2030-4
    • (2010) Rapid Commun Mass Sp , vol.24 , pp. 2030-2034
    • Li, H.1    Yuan, G.2
  • 32
    • 84861800384 scopus 로고    scopus 로고
    • Polydatin protects learning and memory impairments in a rat model of vascular dementia
    • Li RP, Wang ZZ, Sun MX, et al.2012). Polydatin protects learning and memory impairments in a rat model of vascular dementia. Phytomedicine 19:677-81
    • (2012) Phytomedicine , vol.19 , pp. 677-681
    • Li, R.P.1    Wang, Z.Z.2    Sun, M.X.3
  • 33
    • 79952219737 scopus 로고    scopus 로고
    • Effect of polydatin on dynamic changes of excitatory amino acids in cerebrospinal fluid of cerebral hemorrhage rats
    • Liu H, Zhang G, Bie X, et al.2010). Effect of polydatin on dynamic changes of excitatory amino acids in cerebrospinal fluid of cerebral hemorrhage rats. China J Chin Mate Med 35:3038-42
    • (2010) China J Chin Mate Med , vol.35 , pp. 3038-3042
    • Liu, H.1    Zhang, G.2    Bie, X.3
  • 34
    • 80055004410 scopus 로고    scopus 로고
    • Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cells
    • Liu H, Zhao S, Zhang Y, et al.2011). Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cells. J Cell Biochem 112:3695-703
    • (2011) J Cell Biochem , vol.112 , pp. 3695-3703
    • Liu, H.1    Zhao, S.2    Zhang, Y.3
  • 35
    • 0025255537 scopus 로고
    • Influences of 3,40,5-trihydroxystibene 3-beta-mono-D-glucoside on beat rate and injury of cultured newborn rat myocardial cells
    • Luo SF, Yu CL, Zhang PW.1990). Influences of 3,40,5-trihydroxystibene 3-beta-mono-D-glucoside on beat rate and injury of cultured newborn rat myocardial cells. Acta Pharmacol Sin 11:147-50
    • (1990) Acta Pharmacol Sin , vol.11 , pp. 147-150
    • Luo, S.F.1    Yu, C.L.2    Zhang, P.W.3
  • 36
    • 33751108964 scopus 로고    scopus 로고
    • Determination of piceid in rat plasma and tissues by high-performance liquid chromatographic method with UV detection
    • Lv C, Zhang L, Wang Q, et al.2006). Determination of piceid in rat plasma and tissues by high-performance liquid chromatographic method with UV detection. Biomed Chromatogr 20:1260-6
    • (2006) Biomed Chromatogr , vol.20 , pp. 1260-1266
    • Lv, C.1    Zhang, L.2    Wang, Q.3
  • 37
    • 80052025156 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue distribution of 2 3 540-tetrahydroxystilbene- 2-O-b-D-glucoside from traditional Chinese medicine Polygonum multiflorum following oral administration to rats
    • Lv G, Lou Z, Chen S, et al.2011). Pharmacokinetics and tissue distribution of 2,3,5,40-tetrahydroxystilbene-2-O-b-D-glucoside from traditional Chinese medicine Polygonum multiflorum following oral administration to rats. J Ethnopharmacol 137:449-56
    • (2011) J Ethnopharmacol , vol.137 , pp. 449-456
    • Lv, G.1    Lou, Z.2    Chen, S.3
  • 38
    • 77956234963 scopus 로고    scopus 로고
    • Antioxidant activity of resveratrol in several fish lipid matrices: Effect of acylation and glucosylation
    • Medina I, Alcántara D, González MJ, et al.2010). Antioxidant activity of resveratrol in several fish lipid matrices: Effect of acylation and glucosylation. J Agric Food Chem 58:9778-86
    • (2010) J Agric Food Chem , vol.58 , pp. 9778-9786
    • Medina, I.1    Alcántara, D.2    González, M.J.3
  • 39
    • 84885633761 scopus 로고    scopus 로고
    • Polydatin attenuates hypoxic pulmonary hypertension and reverses remodeling through protein kinase C mechanisms
    • Miao Q, Shi XP, Ye MX, et al.2012). Polydatin attenuates hypoxic pulmonary hypertension and reverses remodeling through protein kinase C mechanisms. Int J Mol Sci 13:7776-87
    • (2012) Int J Mol Sci , vol.13 , pp. 7776-7787
    • Miao, Q.1    Shi, X.P.2    Ye, M.X.3
  • 40
    • 82755193717 scopus 로고    scopus 로고
    • Cardioprotective effect of polydatin against ischemia/reperfusion injury: Roles of protein kinase C and mito KATP activation
    • Miao Q, Wang S, Miao S, et al.2011). Cardioprotective effect of polydatin against ischemia/reperfusion injury: Roles of protein kinase C and mito KATP activation. Phytomedicine 19:8-12
    • (2011) Phytomedicine , vol.19 , pp. 8-12
    • Miao, Q.1    Wang, S.2    Miao, S.3
  • 41
    • 77950867414 scopus 로고    scopus 로고
    • Quantitative structureantioxidant activity relationship of trans-resveratrol oligomers, trans-4,40-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: Trans-piceid, cis-piceid, trans-astringin and transresveratrol- 40-O-b-D-glucopyranoside
    • Mikulski D, Molski M.2010). Quantitative structureantioxidant activity relationship of trans-resveratrol oligomers, trans-4,40-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: Trans-piceid, cis-piceid, trans-astringin and transresveratrol- 40-O-b-D-glucopyranoside. Eur J Med Chem 45:2366-80
    • (2010) Eur J Med Chem , vol.45 , pp. 2366-2380
    • Mikulski, D.1    Molski, M.2
  • 42
    • 84885573783 scopus 로고    scopus 로고
    • Protective effects of polydatin on hepatocyte injury induced by pyrogallic acid in mice
    • Mo ZX, Shao HX, Zheng YS.1999). Protective effects of polydatin on hepatocyte injury induced by pyrogallic acid in mice. Pharm Clin Chin Mater Med 15:6-8
    • (1999) Pharm Clin Chin Mater Med , vol.15 , pp. 6-8
    • Mo, Z.X.1    Shao, H.X.2    Zheng, Y.S.3
  • 43
    • 84855408119 scopus 로고    scopus 로고
    • Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system
    • Pastore S, Lulli D, Fidanza P, et al.2012). Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system. Antioxid Redox Sign 16: 314-28
    • (2012) Antioxid Redox Sign , vol.16 , pp. 314-328
    • Pastore, S.1    Lulli, D.2    Fidanza, P.3
  • 44
    • 80051600588 scopus 로고    scopus 로고
    • Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NF-kB and AhR and EGFR-ERK pathway
    • Potapovich AI, Lulli D, Fidanza P, et al.2011). Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NF-kB and AhR and EGFR-ERK pathway. Toxicol Appl Pharm 255:138-49
    • (2011) Toxicol Appl Pharm , vol.255 , pp. 138-149
    • Potapovich, A.I.1    Lulli, D.2    Fidanza, P.3
  • 45
    • 84867297523 scopus 로고    scopus 로고
    • Effect of polydatin on endothelial function in aorta vascular strips of healthy rabbits treated with ADMA
    • Qin J, Chen YZ, Zhou QX, et al.2004). Effect of polydatin on endothelial function in aorta vascular strips of healthy rabbits treated with ADMA. Chin Tradit Herbal Drugs 35:535-8
    • (2004) Chin Tradit Herbal Drugs , vol.35 , pp. 535-538
    • Qin, J.1    Chen, Y.Z.2    Zhou, Q.X.3
  • 46
    • 84872906695 scopus 로고    scopus 로고
    • Polydatin, a natural precursor of resveratrol, induces b-defensin production and reduces inflammatory response
    • Ravagnan G, De Filippis A, Cartení M, et al.2013). Polydatin, a natural precursor of resveratrol, induces b-defensin production and reduces inflammatory response. Inflammation 36:26-34
    • (2013) Inflammation , vol.36 , pp. 26-34
    • Ravagnan, G.1    De Filippis, A.2    Cartení, M.3
  • 47
    • 78651469279 scopus 로고    scopus 로고
    • Study on excretion of stilbene glycoside (THSG) and its beta-cyclodextrin inclusion
    • Ren X, Ouyang H, Wang G, et al.2010). Study on excretion of stilbene glycoside (THSG) and its beta-cyclodextrin inclusion. China J Chin Mater Med 35:2620-3
    • (2010) China J Chin Mater Med , vol.35 , pp. 2620-2623
    • Ren, X.1    Ouyang, H.2    Wang, G.3
  • 48
    • 0041825750 scopus 로고    scopus 로고
    • Glycosylation of resveratrol protects it from enzymic oxidation
    • Reqev-Shoshani G, Shoseyov O, Bilkis I, et al.2003). Glycosylation of resveratrol protects it from enzymic oxidation. Biochem J 374:157-63
    • (2003) Biochem J , vol.374 , pp. 157-163
    • Reqev-Shoshani, G.1    Shoseyov, O.2    Bilkis, I.3
  • 49
    • 27944473247 scopus 로고    scopus 로고
    • Role of peptide primary sequence in polyphenol-protein recognition: An example with neurotensin
    • Richard T, Vitrac X, Merillon JM, et al.2005). Role of peptide primary sequence in polyphenol-protein recognition: An example with neurotensin. Biochim Biophys Acta 1726:238-43
    • (2005) Biochim Biophys Acta , vol.1726 , pp. 238-243
    • Richard, T.1    Vitrac, X.2    Merillon, J.M.3
  • 51
    • 33845334891 scopus 로고    scopus 로고
    • Inhibitory activity of stilbenes on Alzheimer's b-amyloid fibrils in vitro
    • Rivière C, Richard T, Quentin L, et al.2007). Inhibitory activity of stilbenes on Alzheimer's b-amyloid fibrils in vitro. Bioorg Med Chem Lett 15:1160-7
    • (2007) Bioorg Med Chem Lett , vol.15 , pp. 1160-1167
    • Rivière, C.1    Richard, T.2    Quentin, L.3
  • 52
    • 64249166299 scopus 로고    scopus 로고
    • The polyphenol piceid destabilizes preformed amyloid fibrils and oligomers in vitro: Hypothesis on possible molecular mechanisms
    • Rivière C, Delaunay JC, Immel F, et al.2009). The polyphenol piceid destabilizes preformed amyloid fibrils and oligomers in vitro: Hypothesis on possible molecular mechanisms. Neurochem Res 34: 1120-8
    • (2009) Neurochem Res , vol.34 , pp. 1120-1128
    • Rivière, C.1    Delaunay, J.C.2    Immel, F.3
  • 53
    • 0024994218 scopus 로고
    • Influence of 3,40,5- Trihydroxystibene-3-b-mono-D-glucoskle on rabbits' platelet aggregation and thromboxane B2 production in vitro
    • Shan CW, Yang SQ, He HD, et al.1990). Influence of 3,40,5- Trihydroxystibene-3-b-mono-D-glucoskle on rabbits' platelet aggregation and thromboxane B2 production in vitro. Acta Pharmacol Sin 11: 527-30
    • (1990) Acta Pharmacol Sin , vol.11 , pp. 527-530
    • Shan, C.W.1    Yang, S.Q.2    He, H.D.3
  • 54
    • 79955575488 scopus 로고    scopus 로고
    • Hypotensive resuscitation combined with polydatin improve microcirculation and survival in a rabbit model of uncontrolled hemorrhagic shock in pregnancy
    • Sheng C, Yu YH, Zhao KS, et al.2011). Hypotensive resuscitation combined with polydatin improve microcirculation and survival in a rabbit model of uncontrolled hemorrhagic shock in pregnancy. J Surg Res 168:103-10
    • (2011) J Surg Res , vol.168 , pp. 103-110
    • Sheng, C.1    Yu, Y.H.2    Zhao, K.S.3
  • 55
    • 84865703695 scopus 로고    scopus 로고
    • Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice
    • Shi YW, Wang CP, Liu L, et al.2012). Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice. Mol Nutr Food Res 56:1433-44
    • (2012) Mol Nutr Food Res , vol.56 , pp. 1433-1444
    • Shi, Y.W.1    Wang, C.P.2    Liu, L.3
  • 56
    • 4444292329 scopus 로고    scopus 로고
    • Effect of polydatin on phospholipase A2 in lung tissues in rats with endotoxic shock
    • Shu SY, Ling ZY, Wang XY, et al.2004). Effect of polydatin on phospholipase A2 in lung tissues in rats with endotoxic shock. Chin J Traumatol 7:239-43
    • (2004) Chin J Traumatol , vol.7 , pp. 239-243
    • Shu, S.Y.1    Ling, Z.Y.2    Wang, X.Y.3
  • 57
    • 79960606468 scopus 로고    scopus 로고
    • Polydatin up-regulates Clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro
    • Shu SY, Ling ZY, Ye M, et al.2011). Polydatin up-regulates Clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro. BMC Cell Biol 12:31
    • (2011) BMC Cell Biol , vol.12 , pp. 31
    • Shu, S.Y.1    Ling, Z.Y.2    Ye, M.3
  • 58
    • 84867312697 scopus 로고    scopus 로고
    • Comparison of resveratrol and polydatin on antioxidative activities
    • Su D, Zhang BL, Huan ML, et al.2010). Comparison of resveratrol and polydatin on antioxidative activities. Chin Pharma 13:471-3
    • (2010) Chin Pharma , vol.13 , pp. 471-473
    • Su, D.1    Zhang, B.L.2    Huan, M.L.3
  • 59
    • 27244435211 scopus 로고    scopus 로고
    • Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents
    • Sun D, Guo K, Rusche JJ, et al.2005). Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents. Nucleic Acids Res 33: 6070-80
    • (2005) Nucleic Acids Res , vol.33 , pp. 6070-6080
    • Sun, D.1    Guo, K.2    Rusche, J.J.3
  • 60
    • 84885626100 scopus 로고    scopus 로고
    • Effects of polydatin on expression of BDNF in cortex of neonatal rats with hypoxic-ischemic brain damage
    • Sun J, Qu XY, He HM, et al.2012). Effects of polydatin on expression of BDNF in cortex of neonatal rats with hypoxic-ischemic brain damage. Chin J Public Health 28:783-5
    • (2012) Chin J Public Health , vol.28 , pp. 783-785
    • Sun, J.1    Qu, X.Y.2    He, H.M.3
  • 61
    • 84885650148 scopus 로고    scopus 로고
    • In vitro antioxidative effect of polydatin
    • Tian JW, Yang JX.2001). In vitro antioxidative effect of polydatin. Chin Trad Herb Drugs 32:918-20
    • (2001) Chin Trad Herb Drugs , vol.32 , pp. 918-920
    • Tian, J.W.1    Yang, J.X.2
  • 62
    • 0035728851 scopus 로고    scopus 로고
    • Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures
    • Waffo-Téquo P, Hawthorne ME, Cuendet M, et al.2001). Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer 40: 173-9
    • (2001) Nutr Cancer , vol.40 , pp. 173-179
    • Waffo-Téquo, P.1    Hawthorne, M.E.2    Cuendet, M.3
  • 63
    • 78650519957 scopus 로고    scopus 로고
    • Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry
    • Wang D, Zhang Z, Ju J, et al.2011). Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry. J Chromatogr B 879:69-74
    • (2011) J Chromatogr B , vol.879 , pp. 69-74
    • Wang, D.1    Zhang, Z.2    Ju, J.3
  • 64
    • 84155169632 scopus 로고    scopus 로고
    • Protective effects of polydatin against lung ischemia/reperfusion injury and the initial exploration for its mechanism
    • Wang FY, Xu ZJ, Zhang XL, et al.2008). Protective effects of polydatin against lung ischemia/reperfusion injury and the initial exploration for its mechanism. Chin J Appl physiol 24:62-5
    • (2008) Chin J Appl physiol , vol.24 , pp. 62-65
    • Wang, F.Y.1    Xu, Z.J.2    Zhang, X.L.3
  • 65
    • 84885622786 scopus 로고    scopus 로고
    • Protective effect of polydatin on hypoxia-induced injury in rat pulmonary microvascular endothelial cells
    • Wang M, Li ZC, Wang JB.2001). Protective effect of polydatin on hypoxia-induced injury in rat pulmonary microvascular endothelial cells. Northwest Pharmaceut J 26:185-9
    • (2001) Northwest Pharmaceut J , vol.26 , pp. 185-189
    • Wang, M.1    Li, Z.C.2    Wang, J.B.3
  • 66
    • 84859559349 scopus 로고    scopus 로고
    • Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock
    • Wang X, Song R, Bian HN, et al.2012). Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock. Am J Physiol Regul Integr Comp Physiol 302:R805-14
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302
    • Wang, X.1    Song, R.2    Bian, H.N.3
  • 67
    • 84872197349 scopus 로고    scopus 로고
    • Polydatin - A new mitochondria protector for acute severe hemorrhagic shock treatment
    • Wang X, Song R, Chen Y, et al.2013). Polydatin - A new mitochondria protector for acute severe hemorrhagic shock treatment. Expert Opin Investig Drugs 22:169-79
    • (2013) Expert Opin Investig Drugs , vol.22 , pp. 169-179
    • Wang, X.1    Song, R.2    Chen, Y.3
  • 68
    • 31544471630 scopus 로고    scopus 로고
    • Study on decreasing effects of polydatin on blood viscosity in the rat model of acute blood stasis
    • Wang Y, Xue J, Sun XD, et al.2004). Study on decreasing effects of polydatin on blood viscosity in the rat model of acute blood stasis. China Pharm 15:275-7
    • (2004) China Pharm , vol.15 , pp. 275-277
    • Wang, Y.1    Xue, J.2    Sun, X.D.3
  • 69
    • 84865403953 scopus 로고    scopus 로고
    • Multiparameter evaluation of the longevity in C elegans under stress using an integrated microfluidic device
    • Wen H, Shi W, Qin J.2012). Multiparameter evaluation of the longevity in C. elegans under stress using an integrated microfluidic device. Biomed Microdevices 14:721-8
    • (2012) Biomed Microdevices , vol.14 , pp. 721-728
    • Wen, H.1    Shi, W.2    Qin, J.3
  • 70
    • 84872895088 scopus 로고    scopus 로고
    • Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine- sensitized mice
    • Wu MJ, Gong X, Jiang R, et al.2012). Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine- sensitized mice. Int J Immunopathol Pharmacol 25:923-34
    • (2012) Int J Immunopathol Pharmacol , vol.25 , pp. 923-934
    • Wu, M.J.1    Gong, X.2    Jiang, R.3
  • 71
    • 84865293359 scopus 로고    scopus 로고
    • Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-kB signaling pathway in rat glomerular mesangial cells
    • Xie X, Peng J, Huang K, et al.2012). Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-kB signaling pathway in rat glomerular mesangial cells. Mole Cell Endocrinol 362:183-93
    • (2012) Mole Cell Endocrinol , vol.362 , pp. 183-193
    • Xie, X.1    Peng, J.2    Huang, K.3
  • 72
    • 68049084636 scopus 로고    scopus 로고
    • Effects of polydatin from Polygonum cuspidatum on lipid profile in hyperlipidemic rabbits
    • Xing WW, Wu JZ, Jia M, Du J, Zhang H, Qin LP.2009). Effects of polydatin from Polygonum cuspidatum on lipid profile in hyperlipidemic rabbits. Biomed Pharmacother 63:457-62
    • (2009) Biomed Pharmacother , vol.63 , pp. 457-462
    • Xing, W.W.1    Wu, J.Z.2    Jia, M.3    Du, J.4    Zhang, H.5    Qin, L.P.6
  • 73
    • 80054011960 scopus 로고    scopus 로고
    • Protective effect of polydatin on a PC12 cell model of oxygen-glucose deprivation
    • Xu B, Lin HB, Zhou H, et al.2010). Protective effect of polydatin on a PC12 cell model of oxygen-glucose deprivation. J South Med Univ 30: 1041-3
    • (2010) J South Med Univ , vol.30 , pp. 1041-1043
    • Xu, B.1    Lin, H.B.2    Zhou, H.3
  • 74
    • 84874161011 scopus 로고    scopus 로고
    • Effect of polydatin on learning and memory and expression of NR2B in the prefrontal cortex of rats with chronic alcoholism
    • 235
    • Xu CY, Li S, Hao W, et al.2011). Effect of polydatin on learning and memory and expression of NR2B in the prefrontal cortex of rats with chronic alcoholism. Chin J Appl Physiol 27:213-14, 220, 235
    • (2011) Chin J Appl Physiol , vol.27 , pp. 213-220
    • Xu, C.Y.1    Li, S.2    Hao, W.3
  • 75
    • 84874504213 scopus 로고    scopus 로고
    • Effect of polydatin on expression of cdk5 in the prefrontal cortex of rats with chronic alcoholism
    • Xu CY, Li S, Hao W, et al.2012). Effect of polydatin on expression of cdk5 in the prefrontal cortex of rats with chronic alcoholism. Chin J Appl Physiol 28:158-9, 188
    • (2012) Chin J Appl Physiol , vol.28 , pp. 158-188
    • Xu, C.Y.1    Li, S.2    Hao, W.3
  • 76
    • 84867299664 scopus 로고    scopus 로고
    • Influence of polydatin on myocardial function and ultrastructure of LPS infected rats
    • Xue X, Jin CH, Li L, et al.2008). Influence of polydatin on myocardial function and ultrastructure of LPS infected rats. Chin Practical Med 3: 3-4
    • (2008) Chin Practical Med , vol.3 , pp. 3-4
    • Xue, X.1    Jin, C.H.2    Li, L.3
  • 77
    • 79953031514 scopus 로고    scopus 로고
    • Polydatin ameliorates DSS-induced colitis in mice through inhibition of nuclear factor-kappaB activation
    • Yao J, Wang JY, Liu L, et al.2011). Polydatin ameliorates DSS-induced colitis in mice through inhibition of nuclear factor-kappaB activation. Planta Med 77:421-7
    • (2011) Planta Med , vol.77 , pp. 421-427
    • Yao, J.1    Wang, J.Y.2    Liu, L.3
  • 78
    • 0030990079 scopus 로고    scopus 로고
    • In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man-fact or myth
    • Yee S.1997). In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man-fact or myth. Pharm Res 14:763-6
    • (1997) Pharm Res , vol.14 , pp. 763-766
    • Yee, S.1
  • 79
    • 84867864904 scopus 로고    scopus 로고
    • Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca2+ mobilization
    • Yuan M, Li J, Lv J, et al.2012). Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca2+ mobilization. Toxicol Appl Pharmacol 264: 462-9
    • (2012) Toxicol Appl Pharmacol , vol.264 , pp. 462-469
    • Yuan, M.1    Li, J.2    Lv, J.3
  • 80
    • 84867291928 scopus 로고    scopus 로고
    • Effect of piceid on the dog with an acute myocardial infarction model
    • Zhang DQ, Sun LS, Xu JP.2006). Effect of piceid on the dog with an acute myocardial infarction model. Herald Med 25:510-13
    • (2006) Herald Med , vol.25 , pp. 510-513
    • Zhang, D.Q.1    Sun, L.S.2    Xu, J.P.3
  • 81
    • 84866982898 scopus 로고    scopus 로고
    • Protective effects of polydatin from Polygonum cuspidatum against carbon tetrachloride-induced liver injury in mice
    • Zhang H, Yu CH, Jiang YP, et al.2012a). Protective effects of polydatin from Polygonum cuspidatum against carbon tetrachloride-induced liver injury in mice. Plos One 7:e46574
    • (2012) Plos One , vol.7
    • Zhang, H.1    Yu, C.H.2    Jiang, Y.P.3
  • 82
    • 84865187798 scopus 로고    scopus 로고
    • Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-A and SREBP-1c
    • Zhang J, Tan Y, Yao F, et al.2012b). Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-a and SREBP-1c. Mol Med Report 6:815-20
    • (2012) Mol Med Report , vol.6 , pp. 815-820
    • Zhang, J.1    Tan, Y.2    Yao, F.3
  • 83
    • 84885636253 scopus 로고    scopus 로고
    • Effect of polydatin on nonalcoholic fatty liver disease and the TNF-A level in serum
    • Zhang L, Lv ZP.2010). Effect of polydatin on nonalcoholic fatty liver disease and the TNF-a level in serum. LiShizhen Med Mater Med Res :1007-8
    • (2010) LiShizhen Med Mater Med Res , pp. 1007-1008
    • Zhang, L.1    Lv, Z.P.2
  • 84
    • 77956695476 scopus 로고    scopus 로고
    • Polydatin attenuates ischemia/reperfusion-induced apoptosis in myocardium of the rat
    • Zhang LP, Ma HJ, Bu HM, et al.2009). Polydatin attenuates ischemia/reperfusion-induced apoptosis in myocardium of the rat. Acta Physiol Sin 61:367-72
    • (2009) Acta Physiol Sin , vol.61 , pp. 367-372
    • Zhang, L.P.1    Ma, H.J.2    Bu, H.M.3
  • 85
    • 84255212372 scopus 로고    scopus 로고
    • Effect of polydatin on action potential in ventricular papillary muscle of rat and the underlying ionic mechanism
    • Zhang LP, Wei Y, Song SL, et al.2011a). Effect of polydatin on action potential in ventricular papillary muscle of rat and the underlying ionic mechanism. Acta Physiol Sin 63:48-54
    • (2011) Acta Physiol Sin , vol.63 , pp. 48-54
    • Zhang, L.P.1    Wei, Y.2    Song, S.L.3
  • 86
    • 67049155079 scopus 로고    scopus 로고
    • Protective effect of polydatin against ischemia/reperfusion injury in rat heart
    • Zhang LP, Yang CY, Wang YP, et al.2008a). Protective effect of polydatin against ischemia/reperfusion injury in rat heart. Acta Physiol Sin 60:161-8
    • (2008) Acta Physiol Sin , vol.60 , pp. 161-168
    • Zhang, L.P.1    Yang, C.Y.2    Wang, Y.P.3
  • 87
    • 55749115742 scopus 로고    scopus 로고
    • Direct determination of polydatin and its metabolite in rat excrement samples by high-performance liquid chromatography
    • Zhang W, Li Q, Zhu M, et al.2008b). Direct determination of polydatin and its metabolite in rat excrement samples by high-performance liquid chromatography. Chem Pharm Bull 56:1592-5
    • (2008) Chem Pharm Bull , vol.56 , pp. 1592-1595
    • Zhang, W.1    Li, Q.2    Zhu, M.3
  • 88
    • 84863244418 scopus 로고    scopus 로고
    • Effects of polydatin on bleomycininduced pulmonary fibrosis in rats
    • Zhang Y, Chen LY, Liang B.2011b). Effects of polydatin on bleomycininduced pulmonary fibrosis in rats. China J Chin Materia Med 24: 3528-34
    • (2011) China J Chin Materia Med , vol.24 , pp. 3528-3534
    • Zhang, Y.1    Chen, L.Y.2    Liang, B.3
  • 89
    • 84867324485 scopus 로고    scopus 로고
    • Effect of polydatin on ultrastructure of cardiac myocytes in rats with adriamycininduced myocardial damage
    • Zhao J, Li HY, Wang ZH, et al.2010). Effect of polydatin on ultrastructure of cardiac myocytes in rats with adriamycininduced myocardial damage. Acta Acad Med CPAPF 19:629-30, 634
    • (2010) Acta Acad Med CPAPF , vol.19 , pp. 629-634
    • Zhao, J.1    Li, H.Y.2    Wang, Z.H.3
  • 90
    • 1642562659 scopus 로고    scopus 로고
    • The mechanism of polydatin in shock treatment
    • Zhao KS, Jin C, Huang X, et al.2003). The mechanism of polydatin in shock treatment. Clin Hemorheol Microcirc 29:211-17
    • (2003) Clin Hemorheol Microcirc , vol.29 , pp. 211-217
    • Zhao, K.S.1    Jin, C.2    Huang, X.3
  • 91
    • 5044236228 scopus 로고    scopus 로고
    • The regulation and its mechanism of polydatin on the b-adrenoreceptor in cardiac myocytes stimulated by lipopolysaccharide
    • Zhao Q, Huang HX, Jin CH.2004). The regulation and its mechanism of polydatin on the b-adrenoreceptor in cardiac myocytes stimulated by lipopolysaccharide. Chin Pharm Bull 20:769-72
    • (2004) Chin Pharm Bull , vol.20 , pp. 769-772
    • Zhao, Q.1    Huang, H.X.2    Jin, C.H.3
  • 92
    • 34547305522 scopus 로고    scopus 로고
    • Metabolism of trans-resveratrol- 3-O-glucoside in vitro in rat tissues
    • Zhou MJ, Chen XY, Zhong DF.2007). Metabolism of trans-resveratrol- 3-O-glucoside in vitro in rat tissues. Acta Pharm Sin 42:520-4
    • (2007) Acta Pharm Sin , vol.42 , pp. 520-524
    • Zhou, M.J.1    Chen, X.Y.2    Zhong, D.F.3
  • 93
    • 67149130341 scopus 로고    scopus 로고
    • Dose-dependent absorption and metabolism of trans-polydatin in rats
    • Zhou S, Yang R, Teng Z, et al.2009). Dose-dependent absorption and metabolism of trans-polydatin in rats. J Agric Food Chem 57: 4572-9
    • (2009) J Agric Food Chem , vol.57 , pp. 4572-4579
    • Zhou, S.1    Yang, R.2    Teng, Z.3
  • 94
    • 34447092985 scopus 로고    scopus 로고
    • Effects of piceid on blood lipid metabolism, nitric oxide and nitricoxide synthase in experimental hyperlipidemia rats
    • Zhu LX, Jin ZY.2005). Effects of piceid on blood lipid metabolism, nitric oxide and nitricoxide synthase in experimental hyperlipidemia rats. Pharm Clin Chin Materia Med 21:16-18
    • (2005) Pharm Clin Chin Materia Med , vol.21 , pp. 16-18
    • Zhu, L.X.1    Jin, Z.Y.2
  • 95
    • 84867297717 scopus 로고    scopus 로고
    • Effect of polydatin on metabolism of blood lipid of hyperlipidemia rats and its antioxidation
    • Patent Med
    • Zhu LX, Jin ZY.2006). Effect of polydatin on metabolism of blood lipid of hyperlipidemia rats and its antioxidation. Chin Trad Patent Med
    • (2006) Chin Trad
    • Zhu, L.X.1    Jin, Z.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.