Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamsters

Phytomedicine

Volumn 16, Issue 6-7, 2009, Pages 652-658

  Du, Jian ^a   Sun, Lian Na ^a   Xing, Wei Wei ^a,b   Huang, Bao Kang ^a   Jia, Min ^a   Wu, Jin Zhong ^c   Zhang, Hong ^a   Qin, Lu Ping ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Hamster; Hyperlipidaemias; Lipid lowering; Polydatin; Polygonum cuspidatum

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLANT EXTRACT; POLYDATIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL STRUCTURE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CLINICAL EVALUATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MEGADOSE; HAMSTER; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; LIPID DIET; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; POLYGONUM CUSPIDATUM; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTILIPEMIC AGENTS; BODY WEIGHT; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CRICETINAE; GLUCOSIDES; HYPERLIPIDEMIAS; MALE; MESOCRICETUS; POLYGONUM CUSPIDATUM; STILBENES; TRIGLYCERIDES;

CRICETINAE; POLYGONUM CUSPIDATUM;

EID: 67349165065     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2008.10.001     Document Type: Article

References (32)

1. Browning J.D., and Horton J.D. Molecular mediators of hepatic steatosis and liver injury. J. Clin. Invest. 114 (2004) 147-152
2. Chen L., Han Y.S., Yang F.Q., and Zhang T.Y. High-speed counter-current chromatography separation and purification of resveratrol and piceid from Polygonum cuspidatum. J. Chromatogr. A 907 (2001) 343-346
3. Cho I.J., Ahn J.Y., Kim S., Choi M.S., and Ha T.Y. Resveratrol attenuates the expression of HMG-CoA reductase mRNA in hamsters. Biochem. Biophys. Res. Commun. 367 (2008) 190-194
4. Fei H.H., Xiao Z.D., and Gao W. Effects of giant knotweed rhizome medicine on the expressions of RAGE and VEGF of rats with diabetic nephropathy. J. Shandong Univ. (Health Sci.) 46 (2008) 43-47
5. Folch J., Lees M., and Sloane-Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226 (1957) 497
6. Gao X.P., Zhang W.Y., Zou W.J., Su Z., Ji Y.Q., and Liu Z.R. Screening for α-glucosidase inhibitors from extracts of traditional Chinese medicine. Nat. Prod. Res. Dev. 15 (2003) 536-538
7. Hakimoǧlu F., Kizil G., Kanay Z., Kizil M., and Isi H. The effect of ethanol extract of Hypericum lysimachioides on lipid profile in hypercholesterolemic rabbits and its in vitro antioxidant activity. Atherosclerosis 192 (2007) 113-122
8. Hegated D.M., McGandy R.B., Myers M.L., and Stare F.J. Quantitative effects of dietary fat on serum cholesterol in man. Am. J. Clin. Nutr. 17 (1965) 281-295
9. Ji W., and Gong B.Q. Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats. J. Ethnopharmacol. 113 (2007) 318-324
10. Jin C.H., Liu J., Huang X.L., and Zhao K.S. Influence of piceid on the contractility of myocardial cells. Chin. Pharm. Bull. 16 (2000) 400-402
11. Kazi-Aoul T., and Benmiloud M. The Frledewald formula: another restriction?. Clin. Chem. 331 (1987) 301
12. Khor H.T., and Chieng D.Y. Effect of dietary supplementation of tocotrienols and tocopeerols on serum lipids in the hamster. Nutr. Res. 16 (1996) 1393-1401
13. Kris-Etherton P.M., and Dietschy J. Design criteria for studies examining individual fatty acid effects on cardiovascular disease risk factors: human and animal studies. Am. J. Clin. Nutr. 65 (1997) 1590-1596
14. La-Du B.N., Adkins S., Kuo C.L., and Lipsig D. Studies on human serum paraoxonase/arylesterase. J. Chem. Biol. Interact. 87 (1993) 25-34
15. Leitinger N., Tyner T.R., Oslund L., Rizza C., Subbanagounder G., Lee H., Shih P.T., Mackman N., Tigyi G., Territo M.C., et al. Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils. Proc. Natl. Acad. Sci. 96 (1999) 12010-12015
16. Li R.W., Douglas T.D., Maiyoh G.K., Adeli K., and Theriault A.G. Green tea leaf extract improves lipid and glucose homeostasis in a fructose-fed insulin-resistant hamster model. J. Ethnopharmacol. 104 (2006) 24-31
17. Mackness B., Davies G.K., Turkie W., Lee E., Roberts D.H., Hill E., Roberts C., Durrington P.N., and Mackness M.I. Paraoxonase status in coronary heart disease are activity and concentration more important than genotype?. Arterioscler. Thromb. Vasc. Biol. 21 (2001) 1451-1457
18. Mackness M.I., Arrol S., and Durrington P.N. Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein. FEBS Lett. 286 (1991) 152-154
19. Mackness M.I., Arrol S., Abbott C., and Durrington P.N. Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase. Atherosclerosis 104 (1993) 129-135
20. Mackness M.I., Mackness B., Durrington P.N., Fogelman A.M., Berliner J., Lusis A.J., Navab M., Shih D., Fonarow G.C., and Mackness M.I. Paraoxonase and coronary heart disease. Curr. Opin. Lipidol. 9 (1998) 319-324
21. Martinez-Flores H.E., Chang Y.K., Martinez-Bustos F., and Sgarbieri V. Effect of high fiber products on blood lipids and lipoproteins in hamsters. Nutr. Res. 24 (2004) 85-93
22. Ohlsen S. Reducing hyperlipidaemia and CHD. Pharm. J. 273 (2004) 116-118
23. Rice-Evans C.A., Miller N.J., and Paganga G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 2 (1997) 152-159
24. Shan C.W. Effects of polyatin on platelet aggregation of rabbits. Acta Pharm. Sin. 23 (1988) 394-396
25. Shan C.W., Yang S.Q., He H.D., Shao S.L., and Zhang P.W. Influences of 3,4,5-trihyedroxystilbene-3-β-mono-d-glucoside on rabbits' platelet aggregation and thromboxane B2 production in vitro. Acta. Pharm. Sin. 11 (1990) 527-530
26. Shen Z.M., Yin J.W., and Yuan H.B. The hypoglycemic effect of tannin from Polygonum cuspidatum. Nat. Prod. Res. Dev. 16 (2004) 220-221
27. Watson A.D., Berliner J.A., Hama S.Y., La D.B., Faull K.F., Fogelman A.M., and Navab M. Protective effect of high-density lipoprotein associated paraoxonase: inhibition of the biological activity of minimally oxidised low-density lipoprotein. J. Clin. Invest. 96 (1995) 2882-2891
28. Wilson T., Knight T.J., Beitz D.C., Lewis D.S., and Engen R.L. Resveratrol promotes atherosclerosis in hypercholesterolemic rabbits. Life Sci. 59 (1996) 15-21
29. Windmueller H.G., and Spaeth A.E. De novo synthesis of fatty acid in perfused rat liver as a determinant of plasma lipoprotein production. Arch. Biochem. Biophys. 122 (1967) 362-369
30. Wu X.C., and Lu Y. The pharmacological effects and clinical studies progress of Polygonum cuspidatum. ITCM 22 (2005) 22-25
31. Xue L. Pharmacological research progress of Polygonum cuspidatum. China J. Chin. Mater. Med. 25 (2000) 651-653
32. Zhou C.S., Xiang H.Y., Xiao J.B., and Lei Q.F. Quantitative determination of resveratrol and piceid in Polygonum cuspidatum Sieb. et Zucc. by HPLC. Chin. J. Pharm. Anal. 25 (2005) 534-536