Quantitative determination of trans-polydatin, a natural strong anti-oxidative compound, in rat plasma and cellular environment of a human colon adenocarcinoma cell line for pharmacokinetic studies

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 855, Issue 2 SPEC. ISS., 2007, Pages 145-151

  He, Hui ^a   Zhao, Ying ^a,b   Chen, Xijing ^a   Zheng, Yuanting ^a   Wu, Xiaolan ^a   Wang, Rui ^a   Li, Tingting ^a   Yu, Qiangling ^a   Jing, Jing ^a   Ma, Le ^a   Ren, Weichao ^a   Han, Deen ^a   Wang, Guangji ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

HPLC; Pharmacokinetics; Plasma concentration; trans Polydatin

Indexed keywords

BIOASSAY; CELLS; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHARMACOKINETICS; RATS;

CELL SUSPENSIONS; FREEZE THAW CYCLES; MOBILE PHASE; RAT PLASMA; SUPERNATANT LIQUID;

BIOCHEMISTRY;

ANTIOXIDANT; METHANOL; POLYDATIN; SOLVENT; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CANCER CELL CULTURE; CELL STRAIN CACO 2; CELL SUSPENSION; COLON ADENOCARCINOMA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DETERMINATION; FLOW RATE; FREEZE THAWING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SAMPLING; SUPERNATANT; ULTRAVIOLET RADIATION;

RATTUS;

EID: 34547666877     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.04.035     Document Type: Article

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