-
1
-
-
33846002728
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
17222789 10.1016/j.ccr.2006.10.020 1:CAS:528:DC%2BD2sXhtFClsLg%3D
-
Bonnet S, Archer SL, Allalunis-Turner J, et al. (2007) A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 11(1): 37-51
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
-
2
-
-
20544449673
-
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation
-
15806154 10.1038/sj.onc.1208622 1:CAS:528:DC%2BD2MXltFKjt78%3D
-
Buzzai M, Jones RG, Amaravadi RK, et al. (2005) The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene 24(26): 4165-4173
-
(2005)
Oncogene
, vol.24
, Issue.26
, pp. 4165-4173
-
-
Buzzai, M.1
Jones, R.G.2
Amaravadi, R.K.3
-
3
-
-
40749099894
-
Pyruvate-kinase M2 is a phosphotyrosine-binding protein
-
18337815 10.1038/nature06667 1:CAS:528:DC%2BD1cXjt1Gnu7k%3D
-
Christofk HR, Vander Heiden MG, Wu N, et al. (2008) Pyruvate-kinase M2 is a phosphotyrosine-binding protein. Nature 452(7184): 181-186
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 181-186
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Wu, N.3
-
4
-
-
40749163248
-
The M2 splice isoform of pyruvate-kinase is important for cancer metabolism and tumour growth
-
18337823 10.1038/nature06734 1:CAS:528:DC%2BD1cXjt1Gnu74%3D
-
Christofk HR, Vander Heiden MG, Harris MH, et al. (2008) The M2 splice isoform of pyruvate-kinase is important for cancer metabolism and tumour growth. Nature 452(7184): 230-233
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
-
5
-
-
0036176751
-
Positron emission tomography scanning: Current and future applications
-
11818465 10.1146/annurev.med.53.082901.104028 1:CAS:528: DC%2BD38Xitl2msbk%3D
-
Czernin J, Phelps ME (2002) Positron emission tomography scanning: current and future applications. Annu Rev Med 53: 89-112
-
(2002)
Annu Rev Med
, vol.53
, pp. 89-112
-
-
Czernin, J.1
Phelps, M.E.2
-
6
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
18032601 10.1073/pnas.0709747104 1:CAS:528:DC%2BD1cXisVOjtQ%3D%3D
-
DeBerardinis RJ, Mancuso A, Daikhin E, et al. (2007) Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci USA 104(49): 19345-19350
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.49
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
-
7
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
18177721 10.1016/j.cmet.2007.10.002 1:CAS:528:DC%2BD1cXnsFSnsg%3D%3D
-
DeBerardinis RJ, Lum JJ, Hatzivassiliou G, et al. (2008) The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 7(1): 11-20
-
(2008)
Cell Metab
, vol.7
, Issue.1
, pp. 11-20
-
-
Deberardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
-
8
-
-
0020377044
-
Glucose utilization of cerebral gliomas measured by [18F] fluorodeoxyglucose and positron emission tomography
-
6983044 10.1212/WNL.32.12.1323
-
Di Chiro G, DeLaPaz RL, Brooks RA, et al. (1982) Glucose utilization of cerebral gliomas measured by [18F] fluorodeoxyglucose and positron emission tomography. Neurology 32(12): 1323-1329
-
(1982)
Neurology
, vol.32
, Issue.12
, pp. 1323-1329
-
-
Di Chiro, G.1
Delapaz, R.L.2
Brooks, R.A.3
-
9
-
-
57349194139
-
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
-
19029981 10.1038/nm.1890 1:CAS:528:DC%2BD1cXhsVWhu7rI
-
Engelman JA, Chen L, Tan X, et al. (2008) Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med 14(12): 1351-1356
-
(2008)
Nat Med
, vol.14
, Issue.12
, pp. 1351-1356
-
-
Engelman, J.A.1
Chen, L.2
Tan, X.3
-
10
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
-
16766262 10.1016/j.ccr.2006.04.023 1:CAS:528:DC%2BD28Xmt1eksLk%3D
-
Fantin VR, St-Pierre J, Leder P (2006) Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9(6): 425-434
-
(2006)
Cancer Cell
, vol.9
, Issue.6
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
11
-
-
69949124867
-
Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
-
19604589 10.1016/j.radonc.2009.06.025 1:CAS:528:DC%2BD1MXhtFajtL7P
-
Feron O (2009) Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Radiother Oncol 92(3): 329-333
-
(2009)
Radiother Oncol
, vol.92
, Issue.3
, pp. 329-333
-
-
Feron, O.1
-
12
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
21376230 10.1016/j.cell.2011.02.013 1:CAS:528:DC%2BC3MXjsFeqtrk%3D
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5): 646-674
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
52649107626
-
Cancer cell metabolism: Warburg and beyond
-
18775299 10.1016/j.cell.2008.08.021 1:CAS:528:DC%2BD1cXhtFCqs7jK
-
Hsu PP, Sabatini DM (2008) Cancer cell metabolism: Warburg and beyond. Cell 134(5): 703-707
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 703-707
-
-
Hsu, P.P.1
Sabatini, D.M.2
-
14
-
-
61849135453
-
Tumor suppressors and cell metabolism: A recipe for cancer growth
-
19270154 10.1101/gad.1756509 1:CAS:528:DC%2BD1MXjsVals78%3D
-
Jones RG, Thompson CB (2009) Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev 23(5): 537-548
-
(2009)
Genes Dev
, vol.23
, Issue.5
, pp. 537-548
-
-
Jones, R.G.1
Thompson, C.B.2
-
15
-
-
0037441913
-
Overexpression of Glut-1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinoma
-
12569601 10.1002/cncr.11159 1:CAS:528:DC%2BD3sXhsFOnsbs%3D
-
Kunkel M, Reichert TE, Benz P, et al. (2003) Overexpression of Glut-1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinoma. Cancer 97(4): 1015-1024
-
(2003)
Cancer
, vol.97
, Issue.4
, pp. 1015-1024
-
-
Kunkel, M.1
Reichert, T.E.2
Benz, P.3
-
16
-
-
1642345520
-
Evaluation of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography for gastric cancer
-
14961197 10.1007/s00268-003-7191-5
-
Mochiki E, Kuwano H, Katoh H, et al. (2004) Evaluation of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography for gastric cancer. World J Surg 28(3): 247-253
-
(2004)
World J Surg
, vol.28
, Issue.3
, pp. 247-253
-
-
Mochiki, E.1
Kuwano, H.2
Katoh, H.3
-
17
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
19460998 10.1126/science.1160809 1:CAS:528:DC%2BD1MXmtVKlsbg%3D
-
Vander-Heiden MG, Cantley LC, Thompson CB (2009) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324(5930): 1029-1033
-
(2009)
Science
, vol.324
, Issue.5930
, pp. 1029-1033
-
-
Vander-Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
18
-
-
12444279265
-
On the origin of cancer cells
-
13298683 10.1126/science.123.3191.309 1:STN:280:DyaG28%2FltV2ktQ%3D%3D
-
Warburg O (1956) On the origin of cancer cells. Science 123(3191): 309-314
-
(1956)
Science
, vol.123
, Issue.3191
, pp. 309-314
-
-
Warburg, O.1
-
19
-
-
85006768050
-
The Metabolism of Tumors in the Body
-
19872213 10.1085/jgp.8.6.519 1:CAS:528:DyaB2sXitlyhuw%3D%3D
-
Warburg O, Wind F, Negelein E (1927) The Metabolism of Tumors in the Body. J Gen Physiol 8(6): 519-530
-
(1927)
J Gen Physiol
, vol.8
, Issue.6
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
20
-
-
0035394516
-
Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas
-
11431362 1:CAS:528:DC%2BD3MXltVCjsrc%3D
-
Wiesener MS, Münchenhagen PM, Berger I, et al. (2001) Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas. Cancer Res 61(13): 5215-5222
-
(2001)
Cancer Res
, vol.61
, Issue.13
, pp. 5215-5222
-
-
Wiesener, M.S.1
Münchenhagen, P.M.2
Berger, I.3
|