-
1
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
10.1126/science.277.5324.370 1:CAS:528:DyaK2sXkvVels7s%3D
-
Antonsson B, Conti F, Ciavatta A, Montessuit S et al (1997) Inhibition of Bax channel-forming activity by Bcl-2. Science 277:370-372
-
(1997)
Science
, vol.277
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
Montessuit, S.4
-
2
-
-
34247895697
-
Voltage-dependent anion channels are dispensable for mitochondrial- dependent cell death
-
10.1038/ncb1575 1:CAS:528:DC%2BD2sXkslyiur8%3D
-
Baines CP, Kaiser RA, Sheiko T, Craigen WJ, Molkentin JD (2007) Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat Cell Biol 9(5):550-5
-
(2007)
Nat Cell Biol
, vol.9
, Issue.5
, pp. 550-555
-
-
Baines, C.P.1
Kaiser, R.A.2
Sheiko, T.3
Craigen, W.J.4
Molkentin, J.D.5
-
3
-
-
4444380912
-
Bax increases the pore size of rat brain mitochondrial voltage-dependent anion channel in the presence of tBid
-
10.1016/j.bbrc.2004.08.094 1:CAS:528:DC%2BD2cXntlOitb8%3D
-
Banerjee J, Ghosh S (2004) Bax increases the pore size of rat brain mitochondrial voltage-dependent anion channel in the presence of tBid. Biochem Biophys Res Commun 323:310-314
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 310-314
-
-
Banerjee, J.1
Ghosh, S.2
-
4
-
-
0034714009
-
Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspase (FLICA): Correlation with DNA fragmentation
-
10.1006/excr.2000.4955 1:CAS:528:DC%2BD3cXls1antr0%3D
-
Bedner E, Smolewski P, Amstad P, Darzynkiewicz Z (2000) Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspase (FLICA): correlation with DNA fragmentation. Exp Cell Res 259:308-313
-
(2000)
Exp Cell Res
, vol.259
, pp. 308-313
-
-
Bedner, E.1
Smolewski, P.2
Amstad, P.3
Darzynkiewicz, Z.4
-
5
-
-
0031563767
-
Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis
-
10.1006/excr.1997.3718 1:CAS:528:DyaK2sXms1Gku7o%3D
-
Binder C, Binder L, Kroemker M, Schultz M, Hiddemann W (1997) Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis. Exp Cell Res 236:223-230
-
(1997)
Exp Cell Res
, vol.236
, pp. 223-230
-
-
Binder, C.1
Binder, L.2
Kroemker, M.3
Schultz, M.4
Hiddemann, W.5
-
6
-
-
0141923652
-
3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation
-
10.1021/jm034107j 1:CAS:528:DC%2BD3sXnt1Kmsrc%3D
-
Bombrun A, Gerber P, Casi G, Terradillos O, Antonsson B, Halazy S (2003) 3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. J Med Chem 46:4365-4368
-
(2003)
J Med Chem
, vol.46
, pp. 4365-4368
-
-
Bombrun, A.1
Gerber, P.2
Casi, G.3
Terradillos, O.4
Antonsson, B.5
Halazy, S.6
-
7
-
-
64849113485
-
Control of mitochondrial apoptosis by the Bcl-2 family
-
10.1242/jcs.031682 1:CAS:528:DC%2BD1MXjs1Wls7w%3D
-
Brunelle JK, Letai A (2009) Control of mitochondrial apoptosis by the Bcl-2 family. J Cell Sci 122:437-441
-
(2009)
J Cell Sci
, vol.122
, pp. 437-441
-
-
Brunelle, J.K.1
Letai, A.2
-
8
-
-
0036479015
-
Mitochondrial involvement in the point of no return in neuronal apoptosis
-
10.1016/S0300-9084(02)01372-X 1:CAS:528:DC%2BD38XktVCqsL0%3D
-
Chang LK, Putcha GV, Deshmukh M, Johnson EM Jr (2002) Mitochondrial involvement in the point of no return in neuronal apoptosis. Biochimie 84:223-231
-
(2002)
Biochimie
, vol.84
, pp. 223-231
-
-
Chang, L.K.1
Putcha, G.V.2
Deshmukh, M.3
Johnson, Jr.E.M.4
-
9
-
-
0026560014
-
Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system
-
10.1126/science.1313189 1:CAS:528:DyaK38XitFalt7c%3D
-
Dressler K, Mathias S, Kolesnick N (1992) Tumor necrosis factor-α activates the sphingomyelin signal transduction pathway in a cell-free system. Science 255:1715-1718
-
(1992)
Science
, vol.255
, pp. 1715-1718
-
-
Dressler, K.1
Mathias, S.2
Kolesnick, N.3
-
10
-
-
33846309212
-
Bcl-2 Family members and apoptosis, taken to heart
-
10.1152/ajpcell.00229.2006 1:CAS:528:DC%2BD2sXisFCrtLs%3D
-
Gustafsson AB, Gottlieb R (2007) Bcl-2 Family members and apoptosis, taken to heart. Am J Physiol Cell Physiol 292:C45-C51
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Gustafsson, A.B.1
Gottlieb, R.2
-
11
-
-
38849156952
-
Heart mitochondria: Gates of life and death
-
10.1093/cvr/cvm005 1:CAS:528:DC%2BD1cXis12ku7w%3D
-
Gustafsson AB, Gottlieb RA (2008) Heart mitochondria: gates of life and death. Cardiovasc Res 77:334-343
-
(2008)
Cardiovasc Res
, vol.77
, pp. 334-343
-
-
Gustafsson, A.B.1
Gottlieb, R.A.2
-
12
-
-
0030826778
-
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischemia/reperfusion injury
-
10.1023/A:1006879618176 1:CAS:528:DyaK2sXmt1eqs7w%3D
-
Halestrap AP, Connern CP, Griffiths EJ, Kerr PM (1997) Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischemia/reperfusion injury. Mol Cell Biochem 174:167-172
-
(1997)
Mol Cell Biochem
, vol.174
, pp. 167-172
-
-
Halestrap, A.P.1
Connern, C.P.2
Griffiths, E.J.3
Kerr, P.M.4
-
13
-
-
30044433263
-
Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia
-
10.1074/jbc.M505843200 1:CAS:528:DC%2BD2MXhtlCmsb7K
-
Hetz C, Vitte PA, Bombrun A, Rostovtseva TK, Montessuit S, Hiver A, Schwarz MK, Church DJ, Korsmeyer SJ, Martinou JC, Antonsson B (2005) Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia. J Biol Chem 280:42960-42970
-
(2005)
J Biol Chem
, vol.280
, pp. 42960-42970
-
-
Hetz, C.1
Vitte, P.A.2
Bombrun, A.3
Rostovtseva, T.K.4
Montessuit, S.5
Hiver, A.6
Schwarz, M.K.7
Church, D.J.8
Korsmeyer, S.J.9
Martinou, J.C.10
Antonsson, B.11
-
14
-
-
69949132846
-
Detergent-activated BAX protein is a monomer
-
10.1074/jbc.M109.023853 1:CAS:528:DC%2BD1MXhtVGhu7bE
-
Ivashyna O, García-Sánz AJ, Ries J, Christenson ET, Schwille P, Schlesinger PH (2009) Detergent-activated BAX protein is a monomer. J Biol Chem 284:23935-23946
-
(2009)
J Biol Chem
, vol.284
, pp. 23935-23946
-
-
Ivashyna, O.1
García-Sánz, A.J.2
Ries, J.3
Christenson, E.T.4
Schwille, P.5
Schlesinger, P.H.6
-
15
-
-
0028078720
-
Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway
-
10.1073/pnas.91.1.73 1:CAS:528:DyaK2cXhtVCmt70%3D
-
Jarvis WD, Kolesnick RN, Fornari FA, Traylor RS, Gewirtz DA, Grant S (1994) Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proc Natl Acad Sci USA 91:73-77
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 73-77
-
-
Jarvis, W.D.1
Kolesnick, R.N.2
Fornari, F.A.3
Traylor, R.S.4
Gewirtz, D.A.5
Grant, S.6
-
16
-
-
0036850312
-
Bid, Bax and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
10.1016/S0092-8674(02)01036-X 1:CAS:528:DC%2BD38XovVakurc%3D
-
Kuwana T, Mackey MR, Perkins G, Ellisman MH, Latterich M, Schneiter R, Green DR, Newmeyer DD (2002) Bid, Bax and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 111:331-342
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
Mackey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
Green, D.R.7
Newmeyer, D.D.8
-
17
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
10.1016/S0092-8674(00)80434-1 1:CAS:528:DyaK2sXnsFGls70%3D
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
18
-
-
0033911968
-
Ceramide mimics tumor necrosis factor-alpha in the induction of cell cycle arrest in endothelial cells. Induction of the tumor suppressor p53 with decrease in retinoblastoma/protein levels
-
10.1046/j.1432-1327.2000.01436.x 1:CAS:528:DC%2BD3cXlt1Gnurw%3D
-
Lopez-Marure R, Ventura JL, Sanchez L, Montaño LF, Zentella A (2000) Ceramide mimics tumor necrosis factor-alpha in the induction of cell cycle arrest in endothelial cells. Induction of the tumor suppressor p53 with decrease in retinoblastoma/protein levels. Eur J Biochem 267:4325-4333
-
(2000)
Eur J Biochem
, vol.267
, pp. 4325-4333
-
-
Lopez-Marure, R.1
Ventura, J.L.2
Sanchez, L.3
Montaño, L.F.4
Zentella, A.5
-
19
-
-
0038730445
-
Toxic effects of copper-based antineoplastic drugs (Casiopeinas) on mitochondrial functions
-
10.1016/S0006-2952(03)00212-0 1:CAS:528:DC%2BD3sXkt1ylsLk%3D
-
Marin-Hernandez A, Garcia-Mora I, Ruiz-Ramirez L, Moreno-Sanchez R (2003) Toxic effects of copper-based antineoplastic drugs (Casiopeinas) on mitochondrial functions. Biochem Pharmacol 65:1979-1989
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 1979-1989
-
-
Marin-Hernandez, A.1
Garcia-Mora, I.2
Ruiz-Ramirez, L.3
Moreno-Sanchez, R.4
-
20
-
-
70349237249
-
Bax distribution into mitocondrial detergent-resistant microdomains is related to ceramide and cholesterol content in postinchemic hearts
-
10.1111/j.1742-4658.2009.07239.x
-
Martínez-Abundis E, Correa F, Pavón N, Zazueta C (2009) Bax distribution into mitocondrial detergent-resistant microdomains is related to ceramide and cholesterol content in postinchemic hearts. FEBS J 276:5579-5588
-
(2009)
FEBS J
, vol.276
, pp. 5579-5588
-
-
Martínez-Abundis, E.1
Correa, F.2
Pavón, N.3
Zazueta, C.4
-
21
-
-
36749084628
-
Changes in specific lipids regulate Bax-induced mitochondrial permeability transition
-
10.1111/j.1742-4658.2007.06166.x 1:CAS:528:DC%2BD2sXhsVOnsrfL
-
Martinez-Abundis E, Garcia N, Correa F, Franco M, Zazueta C (2007) Changes in specific lipids regulate Bax-induced mitochondrial permeability transition. FEBS J 274:6500-6510
-
(2007)
FEBS J
, vol.274
, pp. 6500-6510
-
-
Martinez-Abundis, E.1
Garcia, N.2
Correa, F.3
Franco, M.4
Zazueta, C.5
-
22
-
-
0025653206
-
The presence of two classes of high-affinity cyclosporin A binding sites in mitochondria. Evidence that the minor component is involved in the opening of an inner-membrane Ca(2+)-dependent pore
-
10.1111/j.1432-1033.1990.tb15667.x 1:CAS:528:DyaK3MXlvF2rsQ%3D%3D
-
McGuinness O, Yafei N, Costi A, Crompton M (1990) The presence of two classes of high-affinity cyclosporin A binding sites in mitochondria. Evidence that the minor component is involved in the opening of an inner-membrane Ca(2+)-dependent pore. Eur J Biochem 194:671-679
-
(1990)
Eur J Biochem
, vol.194
, pp. 671-679
-
-
McGuinness, O.1
Yafei, N.2
Costi, A.3
Crompton, M.4
-
23
-
-
42449109035
-
Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies
-
10.1073/pnas.0800962105 1:CAS:528:DC%2BD1cXksVKit7s%3D
-
Merlini L, Angelin A, Tiepolo T, Braghetta P, Sabatelli P, Zamparelli A, Ferlini A, Maraldi NM, Bonaldo P, Bernardi P (2008) Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies. Proc Natl Acad Sci USA 105:5225-5229
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5225-5229
-
-
Merlini, L.1
Angelin, A.2
Tiepolo, T.3
Braghetta, P.4
Sabatelli, P.5
Zamparelli, A.6
Ferlini, A.7
Maraldi, N.M.8
Bonaldo, P.9
Bernardi, P.10
-
24
-
-
0032422488
-
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
-
10.1073/pnas.95.25.14681 1:CAS:528:DyaK1cXotVGmt7s%3D
-
Narita M, Shimizu S, Ito T, Chittenden T, Lutz RJ, Matzuda H, Tsujimoto Y (1998) Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci USA 95:14681-14686
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14681-14686
-
-
Narita, M.1
Shimizu, S.2
Ito, T.3
Chittenden, T.4
Lutz, R.J.5
Matzuda, H.6
Tsujimoto, Y.7
-
25
-
-
1442310957
-
Structural biology of the Bcl-2 family of proteins
-
10.1016/j.bbamcr.2003.08.012 1:CAS:528:DC%2BD2cXhslWgu7o%3D
-
Petros AM, Olejniczak ET, Fesik SW (2004) Structural biology of the Bcl-2 family of proteins. Biochem Biophys Acta 1644:83-94
-
(2004)
Biochem Biophys Acta
, vol.1644
, pp. 83-94
-
-
Petros, A.M.1
Olejniczak, E.T.2
Fesik, S.W.3
-
26
-
-
1842640369
-
Bid, but not Bax, regulates VDAC channels
-
10.1074/jbc.M310593200 1:CAS:528:DC%2BD2cXis1emu7Y%3D
-
Rostovtseva TK, Antonsson B, Suzuki M, Youle RJ, Colombini M, Bezrukov SM (2004) Bid, but not Bax, regulates VDAC channels. J Biol Chem 279:13575-83
-
(2004)
J Biol Chem
, vol.279
, pp. 13575-13583
-
-
Rostovtseva, T.K.1
Antonsson, B.2
Suzuki, M.3
Youle, R.J.4
Colombini, M.5
Bezrukov, S.M.6
-
27
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
10.1093/emboj/17.6.1675 1:CAS:528:DyaK1cXit1Git74%3D
-
Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, Debatin KM, Krammer PH, Peter ME (1998) Two CD95 (APO-1/Fas) signaling pathways. EMBO J 17:1675-1687
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
28
-
-
0031823480
-
Bcl-2 family proteins as ion-channels
-
10.1038/sj.cdd.4400365 1:CAS:528:DyaK1cXjslGhsrc%3D
-
Schendel SL, Montal M, Reed JC (1998) Bcl-2 family proteins as ion-channels. Cell Death Differ 5:372-380
-
(1998)
Cell Death Differ
, vol.5
, pp. 372-380
-
-
Schendel, S.L.1
Montal, M.2
Reed, J.C.3
-
29
-
-
0034697365
-
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytocrome c
-
10.1074/jbc.275.16.12321 1:CAS:528:DC%2BD3cXisl2jurg%3D
-
Shimizu S, Ide T, Yanagida T, Tsujimoto Y (2000) Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytocrome c. J Biol Chem 275:12321-12325
-
(2000)
J Biol Chem
, vol.275
, pp. 12321-12325
-
-
Shimizu, S.1
Ide, T.2
Yanagida, T.3
Tsujimoto, Y.4
-
30
-
-
0037178790
-
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins
-
10.1074/jbc.M200754200 1:CAS:528:DC%2BD38XlvV2is7o%3D
-
Siskind LJ, Kolesnick R, Colombini M (2002) Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins. J Biol Chem 277:26796-26803
-
(2002)
J Biol Chem
, vol.277
, pp. 26796-26803
-
-
Siskind, L.J.1
Kolesnick, R.2
Colombini, M.3
-
31
-
-
0032504575
-
Mitochondria as regulators of apoptosis: Doubt no more
-
10.1016/S0005-2728(98)00110-8 1:CAS:528:DyaK1cXltFWksLY%3D
-
Susin SA, Zamzami N, Kroemer G (1998) Mitochondria as regulators of apoptosis: Doubt no more. Biochim Biophys Acta 1366:151-165
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 151-165
-
-
Susin, S.A.1
Zamzami, N.2
Kroemer, G.3
-
32
-
-
0034525413
-
VDAC regulation by Bcl-2 family of proteins
-
10.1038/sj.cdd.4400780 1:CAS:528:DC%2BD3MXmsFOnsg%3D%3D
-
Tsujimoto Y, Shimizu S (2000) VDAC regulation by Bcl-2 family of proteins. Cell Death Differ 7:1174-1181
-
(2000)
Cell Death Differ
, vol.7
, pp. 1174-1181
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
33
-
-
0036042248
-
Bax releases cytochrome c preferentially from a complex between porin and adenine nucleotide translocator. Hexokinase activity suppresses this effect
-
10.1023/A:1020383108620 1:CAS:528:DC%2BD38Xnt1agt7s%3D
-
Vyssokikh M, Zorova L, Zorov D, Heimlich G, Jurgensmeier J, Brdiczka D (2002) Bax releases cytochrome c preferentially from a complex between porin and adenine nucleotide translocator. Hexokinase activity suppresses this effect. Mol Biol Rep 29:93-96
-
(2002)
Mol Biol Rep
, vol.29
, pp. 93-96
-
-
Vyssokikh, M.1
Zorova, L.2
Zorov, D.3
Heimlich, G.4
Jurgensmeier, J.5
Brdiczka, D.6
-
34
-
-
0032485845
-
Acidic pH promotes dimerization of Bcl-2 family of proteins
-
10.1021/bi973052i 1:CAS:528:DyaK1cXis12lsbw%3D
-
Xie Z, Schendel S, Matsuyama S, Reed J (1998) Acidic pH promotes dimerization of Bcl-2 family of proteins. Biochemistry 37:6410-6418
-
(1998)
Biochemistry
, vol.37
, pp. 6410-6418
-
-
Xie, Z.1
Schendel, S.2
Matsuyama, S.3
Reed, J.4
|