3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome C release via bax channel modulation

Journal of Medicinal Chemistry

Volumn 46, Issue 21, 2003, Pages 4365-4368

  Bombrun, Agnes ^a   Gerber, Patrick ^a   Casi, Giulio ^a   Terradillos, Olivier ^a   Antonsson, Bruno ^a   Halazy, Serge ^a  

^a SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 PROPANOL; 3,6 DIBROMOCARBAZOLE DERIVATIVE; 3,6 DIBROMOCARBAZOLE PIPERAZINE DERIVATIVE; CYTOCHROME C; CYTOCHROME C INHIBITOR; FLUORESCENT DYE; PIPERAZINE DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; DEGENERATIVE DISEASE; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; ISCHEMIA; PROTEIN SECRETION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARBAZOLES; CYTOCHROME C GROUP; ENZYME INHIBITORS; FLUORESCENT DYES; HELA CELLS; HUMANS; INDICATORS AND REAGENTS; LIPOSOMES; MITOCHONDRIA; PIPERAZINES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141923652     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm034107j     Document Type: Article

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