Detergent-activated BAX protein is a monomer

Journal of Biological Chemistry

Volumn 284, Issue 36, 2009, Pages 23935-23946

  Ivashyna, Olena ^a   García Sáez, Ana J ^b   Ries, Jonas ^b   Christenson, Eric T ^a   Schwille, Petra ^b   Schlesinger, Paul H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOTIC; BAX ACTIVATION; CHEMICAL MECHANISM; CHOLIC ACIDS; FLUORESCENCE CORRELATION SPECTROSCOPY; HIGH MOLECULAR WEIGHT; IN-VITRO; IN-VIVO; INTENSITY DISTRIBUTION; MEMBRANE INSERTION; OCTYL GLUCOSIDES; OUTER MITOCHONDRIAL MEMBRANES; PORE FORMATION; PROTEIN FAMILY; SINGLE-MOLECULE SENSITIVITY; TRITON X-100; TWEEN-20;

ACIDS; AMPHIPHILES; CELL DEATH; CELL MEMBRANES; DYES; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; MICELLES; MOLECULAR WEIGHT; MONOMERS; OLIGOMERIZATION; SOAPS (DETERGENTS);

ACTIVATION ANALYSIS;

3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; CHOLIC ACID; DETERGENT; MONOMER; OCTYL GLUCOSIDE; POLYSORBATE 20; PROTEIN BAX; PROTEIN BCL 2; TRITON X 100;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; CYTOPLASM; FLUORESCENCE CORRELATION SPECTROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE; MOLECULAR WEIGHT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN TRANSPORT;

BCL-2-ASSOCIATED X PROTEIN; DETERGENTS; HELA CELLS; HUMANS; MICELLES; MITOCHONDRIAL MEMBRANES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT;

EID: 69949132846     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.023853     Document Type: Article

References (36)

1. Hsu, Y. T., and Youle, R. J. (1998) J. Biol. Chem. 273, 10777-10783
2. Wolter, K. G., Hsu, Y. T., Smith, C. L., Nechushtan, A., Xi, X. G., and Youle, R. J. (1997) J. Cell Biol. 139, 1281-1292
3. Annis, M. G., Soucie, E. L., Dlugosz, P. J., Cruz-Aguado, J. A., Penn, L. Z., Leber, B., and Andrews, D. W. (2005) EMBO J. 24, 2096-2103
4. Antonsson, B., Montessuit, S., Sanchez, B., and Martinou, J. C. (2001) J. Biol. Chem. 276, 11615-11623
5. Lalier, L., Cartron, P. F., Juin, P., Nedelkina, S., Manon, S., Bechinger, B., and Vallette, F. M. (2007) Apoptosis 12, 887-896
6. Youle, R. J., and Strasser, A. (2008) Nat. Rev. Mol. Cell Biol. 9, 47-59
7. Antonsson, B., Montessuit, S., Lauper, S., Eskes, R., and Martinou, J. C. (2000) Biochem. J. 345, 271-278
8. Suzuki, M., Youle, R. J., and Tjandra, N. (2000) Cell 103, 645-654
9. García-Sáez, A. J., Mingarro, I., Pérez-Payá, E., and Salgado, J. (2004) Biochemistry 43, 10930-10943
10. Lovell, J. F., Billen, L. P., Bindner, S., Shamas-Din, A., Fradin, C., Leber, B., and Andrews, D. W. (2008) Cell 135, 1074-1084
11. le Maire, M., Champeil, P., and Moller, J. V. (2000) Biochim. Biophys. Acta 1508, 86-111
12. Yethon, J. A., Epand, R. F., Leber, B., Epand, R. M., and Andrews, D. W. (2003) J. Biol. Chem. 278, 48935-48941
13. Hsu, Y. T., and Youle, R. J. (1997) J. Biol. Chem. 272, 13829-13834
14. Dewson, G., Snowden, R. T., Almond, J. B., Dyer, M. J., and Cohen, G. M. (2003) Oncogene 22, 2643-2654
15. Hou, Q., and Hsu, Y. T. (2005) Am. J. Physiol. Heart Circ. Physiol. 289, H477-H487
16. Saito, M., Korsmeyer, S. J., and Schlesinger, P. H. (2000) Nat. Cell Biol. 2, 553-555
17. Haustein, E., and Schwille, P. (2004) Curr. Opin. Struct. Biol. 14, 531-540
18. Kask, P., Palo, K., Ullmann, D., and Gall, K. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 13756-13761
19. Tartof, K. D., and Hobbs, C. A. (1987) Focus 9, 12
20. Frezza, C., Cipolat, S., and Scorrano, L. (2007) Nat. Protoc. 2, 287-295
21. Szoka, F., Jr., and Papahadjopoulos, D. (1978) Proc. Natl. Acad. Sci. U.S.A. 75, 4194-4198
22. Christenson, E., Merlin, S., Saito, M., and Schlesinger, P. (2008) J. Mol. Biol. 381, 1168-1183
23. Rika, J., and Binkert, T. (1989) Phys. Rev. A 39, 2646-2652
24. Schwille, P., Meyer-Almes, F. J., and Rigler, R. (1997) Biophys. J. 72, 1878-1886
25. Ohrt, T., Merkle, D., Birkenfeld, K., Echeverri, C. J., and Schwille, P. (2006) Nucleic Acids Res. 34, 1369-1380
26. Kuwana, T., Mackey, M. R., Perkins, G., Ellisman, M. H., Latterich, M., Schneiter, R., Green, D. R., and Newmeyer, D. D. (2002) Cell 111, 331-342
27. Bavdek, A., Gekara, N. O., Priselac, D., Gutiérrez Aguirre, I., Darji, A., Chakraborty, T., Macek, P., Lakey, J. H., Weiss, S., and Anderluh, G. (2007) Biochemistry 46, 4425-4437
28. Anderluh, G., Macek, P., and Lakey, J. H. (2003) Toxicon 42, 225-228
29. Enderlein, J., Gregor, I., Patra, D., and Fitter, J. (2004) Curr. Pharm. Biotechnol. 5, 155-161
30. Meacci, G., Ries, J., Fischer-Friedrich, E., Kahya, N., Schwille, P., and Kruse, K. (2006) Phys. Biol. 3, 255-263
31. Saffarian, S., Li, Y., Elson, E. L., and Pike, L. J. (2007) Biophys. J. 93, 1021-1031
32. Fleming, K. G. (2002) J. Mol. Biol. 323, 563-571
33. Jürgensmeier, J. M., Xie, Z., Deveraux, Q., Ellerby, L., Bredesen, D., and Reed, J. C. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 4997-5002
34. Rodnin, M. V., Posokhov, Y. O., Contino-Pépin, C., Brettmann, J., Kyrychenko, A., Palchevskyy, S. S., Pucci, B., and Ladokhin, A. S. (2008) Biophys. J. 94, 4348-4357
35. Bamber, L., Harding, M., Butler, P. J., and Kunji, E. R. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 16224-16229
36. MacKenzie, K. R., and Fleming, K. G. (2008) Curr. Opin. Struct. Biol. 18, 412-419