Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: Implications for evidence-based therapy of delayed wound healing in diabetes

American Journal of Physiology - Endocrinology and Metabolism

Volumn 305, Issue 8, 2013, Pages

  Bitar, Milad S ^a   Abdel Halim, Samy M ^b   Al Mulla, Fahd ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

^b Sweden Karolinska Institutet Department of Clinical Sciences Danderyd Hospital Stressrehab FoU Danderyd   (Sweden)

Author keywords

Polymerase I and transcript release factor

Indexed keywords

BETA GALACTOSIDASE; CAVEOLIN 1; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HISTONE H2AX; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMALL INTERFERING RNA; THIOREDOXIN REDUCTASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PTRF; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ANTISENSE THERAPY; ARTICLE; ATTENUATION; CELL AGING; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETIC PATIENT; ENZYME ACTIVITY; EVIDENCE BASED MEDICINE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; TISSUE REPAIR; TOTAL ANTIOXIDANT CAPACITY; WOUND HEALING IMPAIRMENT;

POLYMERASE I AND TRANSCRIPT RELEASE FACTOR;

ANIMALS; CAVEOLIN 1; CELL AGING; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; FEMALE; GENE SILENCING; GLUCOSEPHOSPHATE DEHYDROGENASE; MEMBRANE PROTEINS; MOLECULAR TARGETED THERAPY; OXIDATIVE STRESS; RATS; RATS, INBRED STRAINS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN; THIOREDOXIN-DISULFIDE REDUCTASE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION; WOUND HEALING;

EID: 84885580350     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00189.2013     Document Type: Article

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