ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes

DMM Disease Models and Mechanisms

Volumn 5, Issue 3, 2012, Pages 375-388

  Bitar, Milad S ^a   Al Mulla, Fahd ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; INSULIN RECEPTOR SUBSTRATE 1; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE; THIOCTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FEMALE; FIBROBLAST; HYPERCORTISOLISM; INFLAMMATION; INSULIN SENSITIVITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WOUND HEALING IMPAIRMENT;

ANIMALS; DEXAMETHASONE; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; GLUCOSE; HYDROCORTISONE; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-LIKE GROWTH FACTOR I; JNK MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PHENOTYPE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; WOUND HEALING;

RATTUS;

EID: 84860744574     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.007872     Document Type: Article

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