Development of solid dispersions of artemisinin for transdermal delivery

International Journal of Pharmaceutics

Volumn 457, Issue 1, 2013, Pages 197-205

  Shahzad, Yasser ^a   Sohail, Sadia ^b   Arshad, Muhammad Sohail ^b   Hussain, Talib ^a   Shah, Syed Nisar Hussain ^b  

^a UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

^b BAHAUDDIN ZAKARIYA UNIVERSITY   (Pakistan)

Author keywords

Artemisinin; Miscibility; Molecular dynamics; Permeability coefficient; Solid dispersions; Solubility parameter

Indexed keywords

ARTEMISININ; MACROGOL; POVIDONE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SOLUBILITY; INFRARED SPECTROSCOPY; MALE; MISCIBILITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; X RAY DIFFRACTION;

ARTEMISININ; MISCIBILITY; MOLECULAR DYNAMICS; PERMEABILITY COEFFICIENT; SOLID DISPERSIONS; SOLUBILITY PARAMETER;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIMALARIALS; ARTEMISININS; MALE; PERMEABILITY; POLYETHYLENE GLYCOLS; POLYVINYLS; PYRROLIDINES; RABBITS; SKIN; SKIN ABSORPTION;

EID: 84885496637     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.09.027     Document Type: Article

References (40)

1. G.P. Andrews, O.A. Abudiak, and D.S. Jones Physicochemical characterization of hot melt extruded bicalutamide-polyvinylpyrrolidone solid dispersions J. Pharm. Sci. 99 2010 1322 1335
2. M. Ashton, T. Gordi, T.N. Hai, N. Van Huong, N.D. Sy, N.T. Nieu, D.X. Huong, M. Johansson, and L.D. Công Artemisinin pharmacokinetics in healthy adults after 250, 500 and 1000 mg single oral doses Biopharm. Drug Dispos. 19 1998 245 250 (Pubitemid 28218419)
3. H. Bley, B. Fussnegger, and R. Bodmeier Characterization and stability of solid dispersions based on PEG/polymer blends Int. J. Pharm. 390 2010 165 173
4. F. Chamchod, and J.C. Beier Modeling Plasmodium vivax: relapses, treatment, seasonality, and G6PD deficiency J. Theor. Biol. 316 2013 25 34
5. K.L. Chan, K.H. Yuen, S. Jinadasa, K.K. Peh, and W.T. Toh A high-performance liquid chromatography analysis of plasma artemisinin using a glassy carbon electrode for reductive electrochemical detection Planta Med. 63 1997 66 69 (Pubitemid 27112443)
6. D.Q.M. Craig The mechanisms of drug release from solid dispersions in water-soluble polymers Int. J. Pharm. 231 2002 131 144 (Pubitemid 34033673)
7. R.T. Eastman, and D.A. Fidock Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria Nat. Rev. Microbiol. 7 2009 864 874
8. G.L. Flynn, and B. Stewart Percutaneous drug penetration: choosing candidates for transdermal development Drug Dev. Res. 13 1988 169 185 (Pubitemid 19044324)
9. T. Gordi, E. Nielsen, Z. Yu, D. Westerlund, and M. Ashton Direct analysis of artemisinin in plasma and saliva using coupled-column high-performance liquid chromatography with a restricted-access material pre-column J. Chromatogr. B 742 2000 155 162 (Pubitemid 30330933)
10. D.J.W. Grant, and H.G. Brittian H.G.E. Brittian, Physical Characterisation of Pharmaceutical Solids 1995 Marcel Dekker New York
11. D.J. Greenhalgh, A.C. Williams, P. Timmins, and P. York Solubility parameters as predictors of miscibility in solid dispersions J. Pharm. Sci. 88 1999 1182 1190 (Pubitemid 29526305)
12. J. Gupta, C. Nunes, S. Vyas, and S. Jonnalagadda Prediction of solubility parameters and miscibility of pharmaceutical compounds by molecular dynamics simulations J. Phys. Chem. B 115 2011 2014 2023
13. J. Hildebrand, and R. Scott The Solubility of Nonelectrolytes 1950 Reinhold Publ. Corp New York
14. D.L. Klayman Qinghaosu (Artemisinin): an antimalarial drug from China Science 228 1985 1049 1055 (Pubitemid 15227365)
15. M. Langer, M. Höltje, N.A. Urbanetz, B. Brandt, H.D. Höltje, and B.C. Lippold Investigations on the predictability of the formation of glassy solid solutions of drugs in sugar alcohols Int. J. Pharm. 252 2003 167 179 (Pubitemid 36126625)
16. Á.A.N. Lima, J.L. Soares-Sobrinho, J.L. Silva, R.A.C. Corrêa-Júnior, M.A.M. Lyra, F.L.A. Santos, B.G. Oliveira, M.Z. Hernandes, L.A. Rolim, and P.J. Rolim-Neto The use of solid dispersion systems in hydrophilic carriers to increase benznidazole solubility J. Pharm. Sci. 100 2011 2443 2451
17. M. Maniruzzaman, D.J. Morgan, A.P. Mendham, J. Pang, M.J. Snowden, and D. Douroumis Drug-polymer intermolecular interactions in hot-melt extruded solid dispersions Int. J. Pharm. 443 2013 199 208
18. V.M. Meidan, and D. Pritchard A two-layer diffusive model for describing the variability of transdermal drug permeation Eur. J. Pharm. Biopharm. 74 2010 513 517
19. C.F. Rawlinson, A.C. Williams, P. Timmins, and I. Grimsey Polymer-mediated disruption of drug crystallinity Int. J. Pharm. 336 2007 42 48 (Pubitemid 46566483)
20. D. Rigby, H. Sun, and B.E. Eichinger Computer simulations of poly(ethylene oxide): force field, PVT diagram and cyclization behaviour Polym. Int. 44 1997 311 330 (Pubitemid 127618123)
21. N.G. Sahoo, A. Abbas, Z. Judeh, C.M. Li, and K.H. Yuen Solubility enhancement of a poorly water-soluble anti-malarial drug: experimental design and use of a modified multifluid nozzle pilot spray drier J. Pharm. Sci. 98 2009 281 296
22. N.G. Sahoo, M. Kakran, L. Li, Z. Judeh, and R.H. Müller Dissolution enhancement of a poorly water-soluble antimalarial drug by means of a modified multi-fluid nozzle pilot spray drier Mater. Sci. Eng. C 31 2011 391 399
23. M.A. Saleem, S. Bala, and A. Liyakat Aeajaz Effect of different carriers on in vitro permeation of meloxicam through rat skin Indian J. Pharm. Sci. 72 2010 710 718
24. A.T.M. Serajuddln Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs J. Pharm. Sci. 88 1999 1058 1066 (Pubitemid 29480600)
25. S.N.H. Shah, E.R. Mehboob, Y. Shahzad, A. Badshah, V.M. Meidan, and G. Murtaza Developing an efficacious diclofenac diethylamine transdermal formulation J. Food Drug Anal. 20 2012 464 470
26. Y. Shahzad, S.N.H. Shah, M.T. Ansari, R. Riaz, A. Safdar, T. Hussain, and M. Malik Effects of drug-polymer dispersions on solubility and in vitro diffusion of artemisinin across a polydimethylsiloxane membrane Chin. Sci. Bull. 57 2012 1685 1692
27. Y. Shahzad, S.N.H. Shah, S. Atique, M.T. Ansari, F. Bashir, and T. Hussain The evaluation of coated granules to mask the bitter taste of dihydroartemisinin Braz. J. Pharm. Sci. 47 2011 323 330
28. S.M. Soliman, N.S.A. Malak, O.N. El Gazayerly, and A.A.A. Rehim Preparation of celecoxib solid dispersions for dermal application: in vitro characterization and skin irritation test J. Drug Deliv. Sci. Technol. 21 2011 509 516
29. D. Southwell, and B.W. Barry Penetration enhancers for human skin: mode of action of 2-pyrrolidone and dimethylformamide on partition and diffusion of model compounds water, n-alcohols, and caffeine J. Invest. Dermatol. 80 1983 507 514 (Pubitemid 13062264)
30. U.S.H. Svensson, R. Sandström, O. Carlborg, H. Lennernäs, and M. Ashton High in situ rat intestinal permeability of artemisinin unaffected by multiple dosing and with no evidence of P-glycoprotein involvement Drug Metab. Dispos. 27 1999 227 232 (Pubitemid 29072076)
31. S. Thaithong, and G.H. Beale Susceptibility of Thai isolates of Plasmodium falciparum to artemisinine (qinghaosu) and artemether Bull. World Health Organ. 63 1985 617 619 (Pubitemid 16237133)
32. H.A.C. Titulaer, J. Zuidema, and C.B. Lugt Formulation and pharmacokinetics of artemisinin and its derivatives Int. J. Pharm. 69 1991 83 92
33. D.W. Van Krevelen, and P. Hoftyzer Properties of Polymers: Their Estimation and Correlation with Chemical Structure 1976 Elsevier New York
34. A.C. Williams, and B.W. Barry Penetration enhancers Adv. Drug Deliv. Rev. 64 2012 128 137
35. J.W. Wong, and K.H. Yuen Improved oral bioavailability of artemisinin through inclusion complexation with β- and γ-cyclodextrins Int. J. Pharm. 227 2001 177 185 (Pubitemid 32868771)
36. World Health Organization Guidelines for the treatment of malaria Diagnosis of Malaria second ed. 2010 10-11
37. World Health Organization World Malaria Report 2010 World Health Organization Geneva
38. T.-X. Xiang, and B.D. Anderson Molecular dynamics simulation of amorphous indomethacin-poly(vinylpyrrolidone) glasses: solubility and hydrogen bonding interactions J. Pharm. Sci. 102 2013 876 891
39. S.S. Zhao, and M.Y. Zeng Spectrometric high-pressure liquid chromatographic studies on analytical chemistry of Qinghaosu Planta Med. 3 1985 233 237 (Pubitemid 15000784)
40. Q. Zhu, M.T. Harris, and L.S. Taylor Modification of crystallization behavior in drug/polyethylene glycol solid dispersions Mol. Pharm. 9 2012 546 553