-
1
-
-
0029590279
-
Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal
-
Aley, K.O., Green, P.G., Levine, J.D., 1995. Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal. J. Neurosci. 15, 8031-8038.
-
(1995)
J. Neurosci.
, vol.15
, pp. 8031-8038
-
-
Aley, K.O.1
Green, P.G.2
Levine, J.D.3
-
2
-
-
0036258531
-
3 spinal receptor involvement in acute pain in humans
-
3 spinal receptor involvement in acute pain in humans. Anesth. Analg. 94, 1553-1557. (Pubitemid 34556642)
-
(2002)
Anesthesia and Analgesia
, vol.94
, Issue.6
, pp. 1553-1557
-
-
Arcioni, R.1
Della Rocca, M.2
Romano, S.3
Romano, R.4
Pietropaoli, P.5
Gasparetto, A.6
-
3
-
-
34250182092
-
1A and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats
-
DOI 10.1007/s00213-007-0761-8
-
1A and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats. Psychopharmacology 193, 97-105. (Pubitemid 46906628)
-
(2007)
Psychopharmacology
, vol.193
, Issue.1
, pp. 97-105
-
-
Berrocoso, E.1
De Benito, M.D.2
Mico, J.A.3
-
4
-
-
77955306980
-
Differential ATF3 expression in dorsal root ganglion neurons reveal the profile of primary afferents engaged by diverse noxious chemical stimuli
-
Bráz, J.M., Basbaum, A.I., 2010. Differential ATF3 expression in dorsal root ganglion neurons reveal the profile of primary afferents engaged by diverse noxious chemical stimuli. Pain 150, 290-301.
-
(2010)
Pain
, vol.150
, pp. 290-301
-
-
Bráz, J.M.1
Basbaum, A.I.2
-
5
-
-
0028790667
-
Spinal opioid receptors and adenosine release: Neurochemical and behavioural characterization of opioid receptor subtypes
-
Cahill, C.M., White, T.D., Sawynok, J., 1995. Spinal opioid receptors and adenosine release: neurochemical and behavioural characterization of opioid receptor subtypes. J. Pharmacol. Exp. Ther. 275, 84-93.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.275
, pp. 84-93
-
-
Cahill, C.M.1
White, T.D.2
Sawynok, J.3
-
6
-
-
77955579833
-
Tramadol/paracetamol fixed dose combination
-
Dhillon, S., 2010. Tramadol/paracetamol fixed dose combination. Clin. Drug Invest. 30, 711-738.
-
(2010)
Clin. Drug Invest.
, vol.30
, pp. 711-738
-
-
Dhillon, S.1
-
7
-
-
77957773393
-
Tramadol and caffeine produce synergistic interactions on antinociception measured in a formalin model
-
Díaz-Reval, M.I., Carillo-Munguía, N., Martínez- Casas, M., González-Trujano, M.E., 2010. Tramadol and caffeine produce synergistic interactions on antinociception measured in a formalin model. Pharmacol. Biochem. Behav. 97, 357-362.
-
(2010)
Pharmacol. Biochem. Behav.
, vol.97
, pp. 357-362
-
-
Díaz-Reval, M.I.1
Carillo-Munguía, N.2
Martínez-Casas, M.3
González-Trujano, M.E.4
-
10
-
-
77954137780
-
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture
-
Goldman, N., Chen, M., Fujita, T., Xu, Q., Liu, W., Jensen, T.K., Pei, Y., Wang, F., Han, X., Chen, J.F., Schnermann, J., Takano, T., Bekar, L., Tieu, K., Nedergaard, M., 2010. Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nat. Neurosci. 13. (883-839).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 883-839
-
-
Goldman, N.1
Chen, M.2
Fujita, T.3
Xu, Q.4
Liu, W.5
Jensen, T.K.6
Pei, Y.7
Wang, F.8
Han, X.9
Chen, J.F.10
Schnermann, J.11
Takano, T.12
Bekar, L.13
Tieu, K.14
Nedergaard, M.15
-
11
-
-
7444229920
-
Clinical pharmacology of tramadol
-
DOI 10.2165/00003088-200443130-00004
-
Grond, S., Sablotzki, A., 2004. Clinical pharmacology of tramadol. Clin. Pharmaco-kinet. 43, 879-923. (Pubitemid 39447033)
-
(2004)
Clinical Pharmacokinetics
, vol.43
, Issue.13
, pp. 879-923
-
-
Grond, S.1
Sablotzki, A.2
-
12
-
-
33750967055
-
Tramadol, fentanyl and sufentanil but not morphine block voltage-operated sodium channels
-
DOI 10.1016/j.pain.2006.07.003, PII S0304395906003617
-
Haeseler, G., Foadi, N., Ahrens, J., Dengler, R., Hecker, H., Leuwer, M., 2006. Tramadol, fentanyl and sufentanil but not morphine block voltage-operated sodium channels. Pain 126, 234-244. (Pubitemid 44751970)
-
(2006)
Pain
, vol.126
, Issue.1-3
, pp. 234-244
-
-
Haeseler, G.1
Foadi, N.2
Ahrens, J.3
Dengler, R.4
Hecker, H.5
Leuwer, M.6
-
13
-
-
0034070287
-
7 receptor antagonist
-
7 receptor antagonist. Br. J. Pharmacol. 130, 539-548. (Pubitemid 30332971)
-
(2000)
British Journal of Pharmacology
, vol.130
, Issue.3
, pp. 539-548
-
-
Hagan, J.J.1
Price, G.W.2
Jeffrey, P.3
Deeks, N.J.4
Stean, T.5
Piper, D.6
Smith, M.I.7
Upton, N.8
Medhurst, A.D.9
Middlemiss, D.N.10
Riley, G.J.11
Lovell, P.J.12
Bromidge, S.M.13
Thomas, D.R.14
-
14
-
-
33847071314
-
Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy
-
DOI 10.1016/j.ejphar.2006.11.047, PII S0014299906013215
-
Hama, A., Sagen, J., 2007. Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy. Eur. J. Pharmacol. 559, 32-37. (Pubitemid 46274643)
-
(2007)
European Journal of Pharmacology
, vol.559
, Issue.1
, pp. 32-37
-
-
Hama, A.1
Sagen, J.2
-
15
-
-
17744375620
-
A, and N-methyl-D-aspartate receptors expressed in Xenopus oocytes
-
DOI 10.1213/01.ANE.0000150961.24747.98
-
Hara, K., Minami, K., Sata, T., 2005. The effects of tramadol and its metabolite on glycine, gamma-aminobutyric acidA, and N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Anesth. Analg. 100, 1400-1405. (Pubitemid 40577394)
-
(2005)
Anesthesia and Analgesia
, vol.100
, Issue.5
, pp. 1400-1405
-
-
Hara, K.1
Minami, K.2
Sata, T.3
-
16
-
-
84862178356
-
PAPupuncture has localized and long-lasting antinoci-ceptive effects in mouse models of acute and chronic pain
-
Hurt, J.K., Zylka, M.J., 2012. PAPupuncture has localized and long-lasting antinoci-ceptive effects in mouse models of acute and chronic pain. Mol. Pain 8, 28.
-
(2012)
Mol. Pain
, vol.8
, pp. 28
-
-
Hurt, J.K.1
Zylka, M.J.2
-
17
-
-
33747047219
-
Mu opioid receptor-dependent and independent components in effects of tramadol
-
DOI 10.1016/j.neuropharm.2006.05.008, PII S002839080600133X
-
Ide, S., Minami, M., Ishihara, K., Uhl, G.R., Sora, I., Ikeda, K., 2006. Mu opioid receptor-dependent and independent components in effects of tramadol. Neuropharmacology 51, 651-658. (Pubitemid 44215970)
-
(2006)
Neuropharmacology
, vol.51
, Issue.3
, pp. 651-658
-
-
Ide, S.1
Minami, M.2
Ishihara, K.3
Uhl, G.R.4
Sora, I.5
Ikeda, K.6
-
18
-
-
72049119133
-
Evidence for the involvement of glutamatergic and neurokinin 1 receptors in the antinociception elicited by tramadol in mice
-
Jesse, C.R., Nogueira, C.W., 2010. Evidence for the involvement of glutamatergic and neurokinin 1 receptors in the antinociception elicited by tramadol in mice. Pharmacology 85, 36-40.
-
(2010)
Pharmacology
, vol.85
, pp. 36-40
-
-
Jesse, C.R.1
Nogueira, C.W.2
-
19
-
-
0026564002
-
Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat
-
Kayser, V., Besson, J.M., Guilbaud, G., 1992. Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat. Eur. J. Pharmacol. 224, 83-88.
-
(1992)
Eur. J. Pharmacol.
, vol.224
, pp. 83-88
-
-
Kayser, V.1
Besson, J.M.2
Guilbaud, G.3
-
20
-
-
84863196254
-
The antinociceptive effect of intrathecal tramadol in rats: The role of alpha 2-adrenoceptors in the spinal cord
-
Li, C, Chen, S.Q., Chen, B.X., Huang, W.Q., Liu, K.X., 2012. The antinociceptive effect of intrathecal tramadol in rats: the role of alpha 2-adrenoceptors in the spinal cord. J. Anesth. 26, 230-235.
-
(2012)
J. Anesth.
, vol.26
, pp. 230-235
-
-
Li, C.1
Chen, S.Q.2
Chen, B.X.3
Huang, W.Q.4
Liu, K.X.5
-
21
-
-
77957917696
-
Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: Involvement of the NO/cGMP/PKG/KATP signaling pathway
-
Lima, FO., Souza, G.R., Verri, W.A., Parada, CA., Ferreira, S.H., Cunha, F.Q., and Cunha., T. M., 2010. Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway. Pain 151, 506-515.
-
(2010)
Pain
, vol.151
, pp. 506-515
-
-
Lima, F.O.1
Souza, G.R.2
Verri, W.A.3
Parada, C.A.4
Ferreira, S.H.5
Cunha, F.Q.6
Cunha, T.M.7
-
22
-
-
84871918958
-
7 and adenosine A1 receptors, as well as peripheral adenosine A1 receptors, are involved in antinociception by systemic administration of amitriptyline
-
7 and adenosine A1 receptors, as well as peripheral adenosine A1 receptors, are involved in antinociception by systemic administration of amitriptyline. Eur. J. Pharmacol. 698, 213-219.
-
(2013)
Eur. J. Pharmacol.
, vol.698
, pp. 213-219
-
-
Liu, J.1
Reid, A.R.2
Sawynok, J.3
-
23
-
-
84873744018
-
7 and adenosine A1 receptors in the spinal cord and adenosine A1 receptors in the periphery
-
7 and adenosine A1 receptors in the spinal cord and adenosine A1 receptors in the periphery. Neurosci. Lett. 536, 64-68.
-
(2013)
Neurosci. Lett.
, vol.536
, pp. 64-68
-
-
Liu, J.1
Reid, A.R.2
Sawynok, J.3
-
24
-
-
44649170362
-
The analgesic drug, tramadol, acts as an agonist of the transient receptor potential vanilloid-1
-
Marincsák, R., Toth, B.I., Czifra, G., Szabó, T., Kovács, L., Bíró, T., 2008. The analgesic drug, tramadol, acts as an agonist of the transient receptor potential vanilloid-1. Anesth. Analg. 106, 1890-1896.
-
(2008)
Anesth. Analg.
, vol.106
, pp. 1890-1896
-
-
Marincsák, R.1
Toth, B.I.2
Czifra, G.3
Szabó, T.4
Kovács, L.5
Bíró, T.6
-
25
-
-
33847310786
-
Local analgesic efficacy of tramadol following intraplantar injection
-
DOI 10.1016/j.ejphar.2006.11.055, PII S0014299906013112
-
Mert, T., Gunes, Y., Gunay, I., 2007. Local analgesic efficacy of tramadol following intraplantar injection. Eur. J. Pharmacol. 558, 68-72. (Pubitemid 46328871)
-
(2007)
European Journal of Pharmacology
, vol.558
, Issue.1-3
, pp. 68-72
-
-
Mert, T.1
Gunes, Y.2
Gunay, I.3
-
26
-
-
63549124479
-
The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats
-
Nakajima, K., Obata, H., Ito, N., Goto, F., Saito, S., 2009. The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats. Eur. J. Pharmacol. 13, 441-447.
-
(2009)
Eur. J. Pharmacol.
, vol.13
, pp. 441-447
-
-
Nakajima, K.1
Obata, H.2
Ito, N.3
Goto, F.4
Saito, S.5
-
27
-
-
56249135269
-
Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels
-
Nogatomo, K., Kubo, Y., 2008. Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels. Proc. Natl. Acad. Sci. USA 105, 17373-17378.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 17373-17378
-
-
Nogatomo, K.1
Kubo, Y.2
-
28
-
-
33750524000
-
Isobolographic analysis of the dual-site synergism in the antinociceptive response of tramadol in the formalin test in rats
-
DOI 10.1016/j.lfs.2006.07.029, PII S0024320506005947
-
Pozos-Guillén, A.J., Aguirre-Bañueldo, P., Arellano-Guerrero, A., Castañada-Hernández, G., Hoyo-Vadillo, C, Pérez-Urizar, J., 2006. Isobolographic analysis of the dual-site synergism in the antinociceptive response of tramadol in the formalin test in rats. Life Sci. 79, 2275-2282. (Pubitemid 44666068)
-
(2006)
Life Sciences
, vol.79
, Issue.24
, pp. 2275-2282
-
-
Pozos-Guillen, A.J.1
Aguirre-Banuelos, P.2
Arellano-Guerrero, A.3
Castaneda-Hernandez, G.4
Hoyo-Vadillo, C.5
Perez-Urizar, J.6
-
29
-
-
0026512239
-
Opioid and non-opioid components independently contribute to the mechanism of action of tramadol, an "atypical," opioid analgesic
-
Raffa, R.B., Friderichs, E., Reimann, W., Shank, R.P., Codd, E.E., Vaught, J.L, 1992. Opioid and non-opioid components independently contribute to the mechanism of action of tramadol, an "atypical," opioid analgesic. J. Pharmacol. Exp. Ther. 260, 275-285.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.260
, pp. 275-285
-
-
Raffa, R.B.1
Friderichs, E.2
Reimann, W.3
Shank, R.P.4
Codd, E.E.5
Vaught, J.L.6
-
30
-
-
0027429714
-
Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol
-
Raffa, R.B., Friderichs, E., Reimann, W., Shank, R.P., Codd, EE., Vaught, J.L., and Jacoby., H. I., Selve, N., 1993. Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol. J. Pharmacol. Exp. Ther. 267, 331-340. (Pubitemid 23325025)
-
(1993)
Journal of Pharmacology and Experimental Therapeutics
, vol.267
, Issue.1
, pp. 331-340
-
-
Raffa, R.B.1
Friderichs, E.2
Reimann, W.3
Shank, R.P.4
Codd, E.E.5
Vaught, J.L.6
Jacoby, H.I.7
Selve, N.8
-
31
-
-
84857254271
-
AMP is an adenosine A1 receptor agonist
-
Rittiner, J.E., Korboukh, I., Hull-Ryde, EA., Jin, J., Janzen, W.P., Frye, S.V., Zylka, M.J., 2012. AMP is an adenosine A1 receptor agonist. J. Biol. Chem. 287, 5301-5309.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 5301-5309
-
-
Rittiner, J.E.1
Korboukh, I.2
Hull-Ryde, E.A.3
Jin, J.4
Janzen, W.P.5
Frye, S.V.6
Zylka, M.J.7
-
33
-
-
0027183389
-
7) activating cAMP formation
-
7) activating cAMP formation. Proc. Natl. Acad. Sci. USA 90, 8547-8551. (Pubitemid 23277706)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.18
, pp. 8547-8551
-
-
Ruat, M.1
Traiffort, E.2
Leurs, R.3
Tardivel-Lacombe, J.4
Diaz, J.5
Arrang -, J.M.6
Schwartz, J.-C.7
-
34
-
-
84873503433
-
Adenosine and pain
-
Masino, S., Boison, D. (Eds.) Springer, NY
-
Sawynok, J., 2013. Adenosine and Pain. In: Masino, S., Boison, D. (Eds.), Adenosine A Key Link Between Metabolism and Central Nervous System Activity. Springer, NY, pp. 343-360.
-
(2013)
Adenosine a Key Link Between Metabolism and Central Nervous System Activity
, pp. 343-360
-
-
Sawynok, J.1
-
35
-
-
3042633560
-
The formalin test: Characteristics and usefulness of the model
-
Sawynok, J., Liu, X.J., 2004. The formalin test: characteristics and usefulness of the model. Rev. Analg. 7, 145-163.
-
(2004)
Rev. Analg.
, vol.7
, pp. 145-163
-
-
Sawynok, J.1
Liu, X.J.2
-
36
-
-
0038689146
-
Adenosine in the spinal cord and periphery: Release and regulation of pain
-
DOI 10.1016/S0301-0082(03)00050-9
-
Sawynok, J., Liu, X.J., 2003. Adenosine in the spinal cord and periphery: release and regulation of pain. Prog. Neurobiol. 69, 313-340. (Pubitemid 36645052)
-
(2003)
Progress in Neurobiology
, vol.69
, Issue.5
, pp. 313-340
-
-
Sawynok, J.1
Liu, X.J.2
-
38
-
-
84855538107
-
Caffeine inhibits antinociception by acetaminophen in the formalin test by inhibiting spinal adenosine A1 receptors
-
Sawynok, J., Reid, A.R., 2012. Caffeine inhibits antinociception by acetaminophen in the formalin test by inhibiting spinal adenosine A1 receptors. Eur. J. Pharmacol. 674, 248-254.
-
(2012)
Eur. J. Pharmacol.
, vol.674
, pp. 248-254
-
-
Sawynok, J.1
Reid, A.R.2
-
39
-
-
77955387987
-
Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phos-phatidylinositol 4,5-bisphospate
-
Sowa, N.A., Street, S.E., Vihko, P., Zylka, M.J., 2010. Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phos-phatidylinositol 4,5-bisphospate. J. Neurosci. 30, 10282-10293.
-
(2010)
J. Neurosci.
, vol.30
, pp. 10282-10293
-
-
Sowa, N.A.1
Street, S.E.2
Vihko, P.3
Zylka, M.J.4
-
40
-
-
0025035996
-
5-Hydroxytryptamine releases adenosine and cyclic AMP from primary afferent nerve terminals in the spinal cord in vivo
-
DOI 10.1016/0006-8993(90)90194-G
-
Sweeney, M.I., White, T.D., Sawynok, J., 1990. 5-Hydroxytryptamine releases adenosine and cyclic AMP from primary afferent nerve terminals in the spinal cord in vivo. Brain Res. 528, 55-61. (Pubitemid 20292937)
-
(1990)
Brain Research
, vol.528
, Issue.1
, pp. 55-61
-
-
Sweeney, M.I.1
White, T.D.2
Sawynok, J.3
-
41
-
-
77953287373
-
Effects of local tramadol administration on peripheral glutamate-induced nociceptive behaviour in mice
-
Wang, J.T.C., Chung, C.C.W., Whitehead, R.A., Schwarz, S.K.W., Ries, CR., MacLeod, B. A., 2010. Effects of local tramadol administration on peripheral glutamate-induced nociceptive behaviour in mice. Can. J. Anesth. 57, 659-663.
-
(2010)
Can. J. Anesth.
, vol.57
, pp. 659-663
-
-
Wang, J.T.C.1
Chung, C.C.W.2
Whitehead, R.A.3
Schwarz, S.K.W.4
Ries, C.R.5
MacLeod, B.A.6
-
42
-
-
42749096009
-
Involvement of serotonin 2A receptors in the analgesic effect of tramadol in mono-arthritic rats
-
Xie, H., Dong, Z.Q., Ma, F., Bauer, W.R., Wang, X., Wu, G.C, 2008. Involvement of serotonin 2A receptors in the analgesic effect of tramadol in mono-arthritic rats. Brain Res. 1210, 76-83.
-
(2008)
Brain Res.
, vol.1210
, pp. 76-83
-
-
Xie, H.1
Dong, Z.Q.2
Ma, F.3
Bauer, W.R.4
Wang, X.5
Wu, G.C.6
-
43
-
-
77649175141
-
7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-desmethyltramadol, via activation of descending serotonergic pathways
-
7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-desmethyltramadol, via activation of descending serotonergic pathways. Anesthesiology 112, 696-710.
-
(2010)
Anesthesiology
, vol.112
, pp. 696-710
-
-
Yaranates, O.1
Dogrul, A.2
Yidirim, V.3
Sahin, A.4
Sizlan, A.5
Seyrek, M.6
Akgül, O.7
Kozak, O.8
Kurt, E.9
Aypar, U.10
-
44
-
-
79954578322
-
Pain-relieving prospects for adenosine receptors and ectonucleo-tidases
-
Zylka, M.J., 2011. Pain-relieving prospects for adenosine receptors and ectonucleo-tidases. Trends Molec. Med. 17, 188-196.
-
(2011)
Trends Molec. Med.
, vol.17
, pp. 188-196
-
-
Zylka, M.J.1
|