Caffeine inhibits antinociception by acetaminophen in the formalin test by inhibiting spinal adenosine A 1 receptors

European Journal of Pharmacology

Volumn 674, Issue 2-3, 2012, Pages 248-254

  Sawynok, Jana ^a   Reid, Allison R ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Acetaminophen; Adenosine A 1 receptors; Antinociception; Caffeine; Formalin test

Indexed keywords

5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; CAFFEINE; DRINKING WATER; FORMALDEHYDE; PARACETAMOL;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; DRUG RESPONSE; EVOKED RESPONSE; FEMALE; FLUID INTAKE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SPINAL CORD;

ACETAMINOPHEN; ADENOSINE A1 RECEPTOR ANTAGONISTS; ADENOSINE A2 RECEPTOR ANTAGONISTS; ANALGESICS; ANIMALS; CAFFEINE; GENE DELETION; MALE; MICE; PAIN MEASUREMENT; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; SPINAL CORD; TIME FACTORS;

EID: 84855538107     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.10.036     Document Type: Article

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