Computational design of helical peptides targeting TNFα

Angewandte Chemie - International Edition

Volumn 52, Issue 42, 2013, Pages 11059-11062

  Zhang, Changsheng ^a   Shen, Qi ^b   Tang, Bo ^b   Lai, Luhua ^a  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

computational design; helical peptides; protein protein interactions; protein peptide drug; TNF

Indexed keywords

BINDING CONFORMATIONS; COMPUTATIONAL DESIGN; COMPUTATIONAL STRATEGY; HELICAL PEPTIDE; PEPTIDE INHIBITORS; PROTEIN-PROTEIN INTERACTIONS; THERAPEUTIC TARGETS; TUMOR NECROSIS FACTORS;

DIAGNOSIS;

PEPTIDES;

PEPTIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTATIONAL DESIGN; DRUG ANTAGONISM; HELICAL PEPTIDES; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN-PROTEIN INTERACTIONS; PROTEIN/PEPTIDE DRUG; STRUCTURE ACTIVITY RELATION; TNFΑ;

COMPUTATIONAL DESIGN; HELICAL PEPTIDES; PROTEIN-PROTEIN INTERACTIONS; PROTEIN/PEPTIDE DRUG; TNFΑ;

HUMANS; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885461407     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201305963     Document Type: Article

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