Crystal structure of TNF-α mutant R31D with greater affinity for receptor R1 compared with R2

Protein Engineering

Volumn 10, Issue 10, 1997, Pages 1101-1107

  Reed, C ^a   Fu, Z Q ^a   Wu, J ^a   Xue, Y N ^a   Harrison, R W ^a   Chen, M J ^a   Weber, I T ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Crystal structure; TNF mutant; TNF receptor model; Tumor necrosis factor

Indexed keywords

ANTINEOPLASTIC AGENT; ARGININE; ASPARTIC ACID; GLUTAMIC ACID; MUTANT PROTEIN; PROTEIN SUBUNIT; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIFFRACTION; HYDROGEN BOND; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR AFFINITY; RECEPTOR BINDING;

BINDING SITES; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; HUMANS; POINT MUTATION; PROTEIN BINDING; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031468692     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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